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Hepatic alterations during chemotherapy

Om Hepatic alterations during chemotherapy

Acute lymphoid leukemia (ALL) is a malignant disorder characterized by uncontrolled clonal growth and proliferation of immature lymphoid cells of B or T lineage. These leukemic cells invade the bone marrow and spread to the peripheral blood, spleen, lymph nodes and other tissues and become clinically detectable. The origin of this disease is still unknown, however, it is associated with genetic and environmental factors such as exposure to ionizing radiation, chemical agents and alkylating agents. It is the most frequent malignant disease in childhood (80% of all leukemias in children) with an annual incidence of 2-3 cases per 100,000 children.hepatotoxicity is a frequent cause of treatment discontinuation in the maintenance phase of acute lymphoid leukemia. This discontinuation of treatment increases the possibility of hematologic relapse by up to 10%.

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  • Språk:
  • Engelsk
  • ISBN:
  • 9786207131235
  • Bindende:
  • Paperback
  • Utgitt:
  • 5. mars 2024
  • Dimensjoner:
  • 152x229x3 mm.
  • Vekt:
  • 91 g.
  Gratis frakt
Leveringstid: 2-4 uker
Forventet levering: 27. desember 2024
Utvidet returrett til 31. januar 2025

Beskrivelse av Hepatic alterations during chemotherapy

Acute lymphoid leukemia (ALL) is a malignant disorder characterized by uncontrolled clonal growth and proliferation of immature lymphoid cells of B or T lineage. These leukemic cells invade the bone marrow and spread to the peripheral blood, spleen, lymph nodes and other tissues and become clinically detectable. The origin of this disease is still unknown, however, it is associated with genetic and environmental factors such as exposure to ionizing radiation, chemical agents and alkylating agents. It is the most frequent malignant disease in childhood (80% of all leukemias in children) with an annual incidence of 2-3 cases per 100,000 children.hepatotoxicity is a frequent cause of treatment discontinuation in the maintenance phase of acute lymphoid leukemia. This discontinuation of treatment increases the possibility of hematologic relapse by up to 10%.

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