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  • Spar 13%
    - The Health Scholar's Toolbox
    av April S Fitzgerald
    1 103,-

    Academic medical centers continue to require evidence of scholarly activity for their faculty to maintain their appointment and to advance in promotion/rank. For some, training to know how to obtain evidence of scholarship was obtained through fellowship where information was passed from mentor to mentee in an apprenticeship fashion without a formalized text to follow to obtain the information. In fellowship, information might flow through word-of-mouth or articles handed down out to a mentee. Others in fellowship develop skills by taking classes as part of an additional master's degree program such as a Master of Public Health.For health professionals who enter an academic institution without having gone through a fellowship program, they are still expected to perform scholarly activity but don't have the benefit of having done the apprenticeship to learn the skills, so unless they decide to find a course, obtain a master's degree, or find a fellowship, they have no way to gain the necessary skills and are at risk of losing their appointment and have no hope of progressing in promotion.This text provides a comprehensive toolbox for the academic who needs these skills to survive. It serves as a valuable resource for health professionals - physicians, nurses, pharmacists, physical therapists, and allied professionals - as well as scientists, and students, with the steps necessary to take their educational endeavors from idea to implementation through dissemination. Beginning with the concept of "What is Scholarship", the authors walk the reader through the concepts of how to find your niche, look through the literature to check for a gap, design a question, consider evaluation and outcomes, be aware of ethical considerations, plan a project, look for support, find mentorship, prepare an abstract, present a poster, disseminate a project, and lead a team. All chapters are written by experts in the subject matter.

  • Spar 15%
    - Bedside Approach to the Physical Examination
    av Steven H Yale
    1 451,-

    This book provides a novel method to teach eponymically named physical signs of the alimentary tract and intrabdominal organs. The focus is on the historical aspect of the named signs, how to perform the sign described by the author, and the pathophysiologic mechanisms involved in eliciting a positive test. The goal is to guide the reader to appreciate how these bedside signs provide a more profound understanding of the mechanism of disease. By doing so, they become more than simply rote memorization but an appreciation of how a direct hands-on assessment involving observing, engaging, listening, and touching the patient assists in diagnosis. Hence, these techniques provided the additional benefit of better connecting the practitioner to the patients and maintaining the art of medicine, which is rapidly losing its foothold within the medical community. This book will serve as a teaching tool for learners, teachers, and practicing physicians to preserve the art of the physical examination using a form of a case-based teaching and learning style approach. Illustrations throughout the text provide a visual representation of how to perform the sign. The authors believe this method of teaching and learning is more meaningful to the student in that they will be able to associate the name with the person's historical features, the sign, and its pathophysiologic mechanism(s). Gastrointestinal Eponymic Signs is a must-have resource for medical students, residents, fellows, teaching faculty, and any practicing physician seeking to understand how physical examination signs assist in diagnosis.

  • - Die Entstehung Von Sturmen Und Anderen Atmospharischen Gefahren
    av Helmut Kraus
    723,-

    1 Einleitung.- 1.1 Wetter: Faszination und Gefahr.- 1.2 Kann man das Wetter leicht verstehen?.- 1.3 Unwetter.- 1.4 Nehmen die atmosphärischen Gefahren zu?.- 2 Einige Grundlagen aus der Meteorologie.- 2.1 Die Zusammensetzung der Luft.- 2.2 Atmosphärische Bewegungssysteme.- 2.3 Der Luftdruck.- 2.4 Der Wind und seine Auswirkungen.- 2.5 Kräfte, die die horizontale Windgeschwindigkeit bestimmen.- 2.5.1 Druckgradientkraft und Corioliskraft.- 2.5.2 Der geostrophische Wind.- 2.5.3 Der Gradientwind.- 2.5.4 Der Einfluss der Reibung.- 2.5.5 Systeme, bei denen die Corioliskraft nur eine kleine Rolle spielt.- 2.5.6 Windprofile in der Atmosphärischen Grenzschicht.- 2.6 Temperaturänderung mit der Höhe.- 2.6.1 Die mittlere Temperaturschichtung.- 2.6.2 Die Temperaturänderung eines trocken auf-oder absteigenden Luftteilchens.- 2.6.3 Die Temperaturänderung eines mit Wasserdampf gesättigten auf-oder absteigenden Luftteilchens.- 2.6.4 Inversionen.- 2.7 Stabilität der Atmosphäre.- 2.8 Änderung der Temperatur in der Horizontalen.- 2.8.1 Warme und kalte Luftsäulen nebeneinander.- 2.8.2 Allmählicher Übergang.- 2.8.3 Fronten.- 2.9 Wolkenteilchen, Niederschlagsteilchen und Niederschlag.- 3 Die Allgemeine Zirkulation der Atmosphäre.- 4 Lokale Stürme (Gewitter).- 4.1 Entstehung der Lokalen Stürme (Gewitter).- 4.1.1 Entwicklung von Cumulus-Wolken.- 4.1.2 Single-cell Storms.- 4.1.3 Multi-cell Storms.- 4.1.4 Supercell Storms.- 4.1.5 Tornados.- 4.1.6 Mesoskalige Konvektive Komplexe.- 4.2 Gefahren und Schäden durch Lokale Stürme.- 4.2.1 Downbursts und Sturm.- 4.2.2 Hagel.- 4.2.3 Starkregen und Überflutungen.- 4.2.4 Blitzschlag.- 4.2.5 Tornados.- 5 Tropische Zyklonen.- 5.1 Das Phänomen.- 5.2 Entstehung.- 5.3 Gefahren und Schäden durch Tropische Zyklonen.- 6 Mittelbreitenzyklonen.- 6.1 Entstehung.- 6.2 Struktur.- 6.3 Zentral-, Rand-und Mesozyklonen.- 6.4 Gefahren und Schäden durch Mittelbreitenzyklonen.- 6.4.1 Stürme.- 6.4.2 Hochwasser, Überflutungen.- 6.4.3 Blizzards.- 6.4.4 Frontgewitter, große Schneefälle, Rauhfrost und Rauheis.- 7 Risiken bei "friedlichem" Wetter.- 7.1 Schwüle.- 7.2 Große Hitze und große Kälte.- 7.3 Nebel.- 7.4 Glätte.- 7.5 Luftverunreinigungen, Smog.- Anhang A: Der Atmosphäre innewohnende Energien.- A.1 Definitionen, Einheiten und Umrechnungen.- A.2 Leistung.- A.3 Energie.- A.4 Energieflussdichten.- A.5 In der Atmosphäre enthaltene Energien (grobe Abschätzungen).- Anhang B: Unterschiedliche Angabe von Windstärken.- Anhang C: Hochwasserschäden weltweit von 1993 bis 2002.- Anhang D: "Wetterversicherungen".- Sachwortverzeichnis.

  • Spar 10%
    - From Mind Maps to Ontologies
    av C Maria Keet
    698,-

    The main aim of this book is to introduce a group of models and modelling of information and knowledge comprehensibly. Such models and the processes for how to create them help to improve the skills to analyse and structure thoughts and ideas, to become more precise, to gain a deeper understanding of the matter being modelled, and to assist with specific tasks where modelling helps, such as reading comprehension and summarisation of text. The book draws ideas and transferrable approaches from the plethora of types of models and the methods, techniques, tools, procedures, and methodologies to create them in computer science. This book covers five principal declarative modelling approaches to model information and knowledge for different, yet related, purposes. It starts with entry-level mind mapping, to proceed to biological models and diagrams, onward to conceptual data models in software development, and from there to ontologies in artificial intelligence and all the way to ontology in philosophy. Each successive chapter about a type of model solves limitations of the preceding one and turns up the analytical skills a notch. These what-and-how for each type of model is followed by an integrative chapter that ties them together, comparing their strengths and key characteristics, ethics in modelling, and how to design a modelling language. In so doing, we'll address key questions such as: what type of models are there? How do you build one? What can you do with a model? Which type of model is best for what purpose? Why do all that modelling? The intended audience for this book is professionals, students, and academics in disciplines where systematic information modelling and knowledge representation is much less common than in computing, such as in commerce, biology, law, and humanities. And if a computer science student or a software developer needs a quick refresher on conceptual data models or a short solid overview of ontologies, then this book will serve them well.

  • av Kurt Michel
    693,-

  • Spar 15%
    - Evolutionary and Quantitative Genetics Brought Up-To-Date
    av José M Álvarez-Castro
    1 682,-

    Genetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked lociArbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted forBoth effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked outPopulations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associationsbetween/among genes and environments)All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.

  • Spar 15%
    av Miranda Louwerse
    1 566,-

    This thesis addresses deep questions that cut to the physical and informational essence of central chemical quantities such as transition paths and reaction mechanisms and proposes fundamental new connections between transition-path theory, linear-response theory, nonequilibrium thermodynamics, and information theory. The author investigates slow, energetically efficient driving protocols that drive a system between conformations corresponding to endpoints of a reaction, aiming to find connections between principles of efficient driving and the spontaneous transition mechanism in the absence of driving. First, an alternative perspective of transition-path theory is developed that unifies it with stochastic thermodynamics to describe flows of entropy, energy, and information during the reaction. This also provides an optimization criterion for selecting collective variables. Next, protocols are designed which invert the magnetization of a 3×3 Ising model with minimal energetic cost, and it is determined that using multiple control parameters allows the system to be driven along a fast-relaxing pathway between reaction endpoints. Finally, the author compares these protocols with the spontaneous transition mechanism for magnetization inversion in the same Ising model, finding that designed protocols capture general features of the spontaneous mechanism and energetics given the constraints on the control parameters. This work represents a major step forward in our understanding of rare events and provides a basis for investigating the connection between efficient protocols and spontaneous transition mechanisms which can be further probed in a wider variety of systems.

  • Spar 15%
    - A Comprehensive Guide
    av Tony Yaksh
    2 416,-

    This book is a comprehensive reference of the neuraxial route for the delivery of therapeutics. It reviews the historical evolution of this approach from its inception in the later 1800's to present day. This amply referenced text covers basic discussions of spinal anatomy, embryogenesis, neuraxial vascularity, cerebrospinal fluid flow dynamics and parenchymal molecule movement. The pharmacokinetic and pharmacodynamic properties of different intrathecal agents are explored in detail with particular reference to clinical correlates in pain and spasticity. Particular attention is paid to the issues relevant to preclinical models of intrathecal delivery and the assessment of spinal pathologies arising from acute and chronic intrathecal drug delivery. Chapters provide essential discussions of clinical aspects of patient care, including patient evaluation and screening, trialing and device management, troubleshooting problems and addressing complications, best practices, cost-effectiveness and future of the therapy. Clinicians and researchers who practice intrathecal therapy and study neuraxial mechanisms will find Neuraxial Therapeutics, to be an invaluable guide to this treatment modality.

  • - Folgeband 4: Stoffe A-K
    av Franz V Bruchhausen
    693,-

    Dieser Band des Gebietes Stoffe enthAlt in alphabetischer Reihenfolge als ErgAnzung zum Hauptwerk Monographien A1/4ber Arzneistoffe, Hilfsstoffe, Impfstoffe und Sera sowie Reagenzien. In den Monographien werden Aussagen A1/4ber die Synthese, die Eigenschaften, die Erkennung, die Reinheit, den Gehalt, die Wirkung und die medizinische Anwendung gemacht. Von besonderer Bedeutung sind Stoffe des DAB und von in Europa gA1/4ltigen ArzneibA1/4chern.

  • - Verfassungsrechtliche Grundlagen - Gesetze
    av Friedrich Krzizek
    943,-

  • Spar 14%
    av Isabelle Aubert
    1 335,-

    On the occasion of the 100th anniversary of the foundation of the Institute for Social Research in Frankfurt am Main, in 1923, this book aims at shedding light on the archives of some of the key thinkers of Critical Theory of Society, also well known as "Frankfurt School". To pay homage to this current of thought, this contributed volume aims to make the archives speak for themselves, to show the public the quantity of unpublished material still existing by the authors of the Critical Theory which are now in funds in different parts of the world (in Germany, in Italy, or in the United States), and to show that Critical Theory remains alive 100 years after its inception.The volume starts by presenting the archives of Karl Marx and Friedrich Engels, the thinkers who inspired Critical Theory, and the archives of the Institute for Social Research itself. Then it dedicates separate sections to the archives of Walter Benjamin, Max Horkheimer, Theodor W. Adorno, Friedrich Pollock, Herbert Marcuse, Leo Löwenthal and Jürgen Habermas. The book is composed of chapters written by researchers and editors who worked in the different fonds, as well as chapters written by or interviews with researchers who were or are in charge of some of the archives, or who are especially familiar with the material. The Archives of Critical Theory will be an invaluable tool for researchers in many disciplines working with Critical Theory of Society, such as Sociology, Anthropology, Political Science, Philosophy, History, Education, Law and Cultural Studies, among others. Readers will find information about the content of each archive and the history of its constitution. The various contributions present many ways in which the materials may be explored and explain how such explorations affected or may yet affect the state of the research.

  • Spar 16%
    av Benoist Schaal
    2 376,-

    The 15th Meeting on Chemical Signals in Vertebrates (CSiV) reunited participants from 20 countries from 5 continents who "electronically commuted" to Dijon, France, during three days (3-5 November 2021). This virtual meeting was a great opportunity to share information on how amphibians, reptiles, birds, and mammals communicate through chemosignals and integrate their environment through chemical cues. Scientists from varied disciplines ranging from biology and psychology to chemistry and biostatistics attended the meeting to share their research on how vertebrates produce and release chemical cues and signals, how they detect, discriminate, process, and interpret them; how they respond to them behaviorally, physiologically, and/or neurally in adaptive ways; how the typical or atypical environment modulates such chemocommunication loops, and chemoreception in general. In total, this 2021 CSiV meeting presented important new findings, representative of the growing points in the rapidly expanding field of research on chemocommunication among vertebrates. As appreciated by D Müller-Schwarze (a well-known pioneer in the field and the founding father of the book series in question) in his foreword to the meeting, "Our field has broadened to new horizons: besides multicomponent cues, we now learn about multisource and multifunction chemical signals. The range of study animals and settings has become richer, and we have learned enough that practical applications are becoming realistic." This proceedings documents key presentations from this virtual conference.

  • Spar 12%
    av Alfred Göpfert
    930,-

    This book discusses basic tools of partially ordered spaces and applies them to variational methods in Nonlinear Analysis and for optimizing problems. This book is aimed at graduate students and research mathematicians.

  • av Hede Helfrich
    351,-

    This textbook of cross-cultural or cultural psychology clarifies exciting questions about differences and similarities between cultures: Are people of other cultural origins different from us? Or are similar deep structures of thinking, feeling, and acting hidden beneath the surface of the exotic or threatening foreign? But why do conspicuous differences in behaviour occur, and how can they be explained? - In our globalised world, in which members of different cultures meet more and more frequently due to economic relations, internet communication and migration movements, these topics are increasingly discussed emotionally - cultural psychology responds to this with scientifically sound contributions. In addition, it sees itself as an interdisciplinary discipline that critically examines the supposedly universal psychological laws of perception, feeling and thinking that have been established in Western culture.

  • Spar 15%
    av Ranjita Shegokar
    1 682,-

    The Peritoneal cavity (PC) is the key metastatic site for intra-abdominal malignancies (e.g., GI tract and rectal cancer). PC sites can be used to target several other diseases where lymphatic drug delivery is desired without dumping large amounts of the drug. Till recently, it was thought that treatment with curative intent was impossible but that was challenged by the introduction of cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC), and PIPAC (pressurized intraperitoneal aerosol chemotherapy). Recently, a growing number of preclinical and clinical studies advocate intraperitoneal (IP) chemotherapy as an alternative post-operative therapy for cancer. Although their effectiveness has been proven both experimentally and clinically, there is still little understanding of the role of drug delivery systems (DDS) in targeting drugs in the intraperitoneal (IP) cavity.There are two main challenges one posed by IP cavity where the residence time of a small molecular weight drug (In summary, challenges like delivery to IP cavity, tumor or organ-specific targeting, efficient tissue penetration, optimal cellular uptake and intracellular residence of a drug, biocompatibility, toxicity, etc can be easily solved by smartly designing functional drug delivery systems (both nano and micro). Nanotechnologies have always fascinated humans for several decades and are now widely explored in the biomedical field. Diverse types of nanoparticles are being explored around the world, some examples include biodegradable nanoparticles, green nanoparticles, polymeric nanoparticles, lipid nanoparticles, metal nanoparticles, graphene, carbon nanotubes, and several others. Now a day's nanoparticles are gaining interest for drug targeting of chemotherapeutic drugs, immunotherapy, and gene delivery. Whereas microparticles can be explored for delayed drug delivery to the peritoneal cavity due to relatively slow removal from IP fluid. Hydrogels or other adhesive drug delivery may help to enhance peritoneal adhesions; thereby maintaining the balance between benefit and risk. Overall, drug delivery systems are key in IP targeting. That means drug delivery specialist and clinician needs to be connected to get the best out of this route of drug administration.The present book is a link between pharmaceutical scientists (drug formulators), clinicians, toxicologists, and regulatory experts. This book also provides a new perspective to researchers to divert or guide their research in an optimal way. Exploring Drug Delivery to the Peritoneum serves as a platform for upcoming technologies especially in the medical devices sector to face up and show potential in delivering drugs. It is a chance for commercial partners like insurance companies and the pharma industry to explore this direction.

  • Spar 16%
    av Clark a Rosen
    2 376,-

    This book provides the laryngeal surgeon with essential background information on laryngological disorders, step-by-step surgical information, and key pearls and pitfalls for laryngeal surgery. The field of laryngeal surgery for voice, swallowing, and airway pathologic conditions has dramatically changed over the last 20 years, and the impetus for this book was to reflect these major paradigm shifts and bring together in one place the essential information on the rapidly growing and changing field of laryngeal surgery. Introductory chapters provide a foundation for the diagnosis and preoperative management of laryngeal pathological conditions. These are followed by the procedural chapters, which encompass a wide range of laryngeal procedures. They have been organized around the broad categories of phonomicrosurgery, awake laryngeal surgery, laryngeal framework surgery, and open airway reconstruction. Each procedural chapter is brief, consisting of five to ten pages, and presents progressive instructions for different laryngeal surgical approaches. The individual steps of the procedure are clearly demonstrated through a series of high-quality intraoperative photos and schematic illustrations. In addition, key aspects of certain procedures are accompanied by a short video. All pertinent information regarding equipment, instrumentation, post-operative care, and possible complications associated with the surgical approach is summarized in bullet format at the end of each chapter. Most of the laryngeal procedures feature an expert commentator who has provided unique insights on important steps and different approaches to the described surgical procedure to provide the reader a variety of perspectives. Operative Techniques in Laryngology is aimed at general otolaryngologists, residents, laryngology fellows, and laryngologists. The emergence and growth of laryngology as a sub-specialty of otolaryngology has established this field as an important partof general otolaryngology training.

  • - Exploring the Approaches of United Nations Security Council Member-States
    av Judith Nora Hardt
    1 090,-

    The speed and scale of climate change presents unique and potentially monumental security implications for individuals, future generations, international institutions and states. Long-dominant security paradigms and policies may no longer be appropriate for dealing with these new security risks of the Anthropocene. In response to this phenomenon, this book investigates how states have reacted to these new challenges and how their different understandings of the climate-security nexus might shape global actions on climate change. It focuses on the perceptions, framings, and policies of climate security by members of the United Nations Security Council (UNSC), the world's highest ranking multilateral security forum. Empirically, the book presents detailed, bottom-up case studies from local authors of every UNSC member state in 2020. It combines this with an innovative theoretical approach spanning national, human and ecological security that helps to capture the complex dynamics of state-led approaches to dealing with security in the Anthropocene. This book therefore offers readers a compelling picture of climate-security politics in the UNSC, beyond Council debates and resolutions. By comparing and contrasting how different framings of climate security impact various policy sectors of members states, the authors are able to assess the barriers and opportunities for addressing climate security locally and globally."This timely contribution to the literature on climate security examines the under-analysed relationship between the policy approaches of key countries at the national, and at the international level. Policy alignment at multiple levels of governance will be critical if we are to respond adequately to the ubiquitous challenges posed by climate change and variability." Shirley Scott, Head of School and Professor, School of Humanities and Social Sciences, UNSW Canberra at the Australian Defence Force Academy (Australia)."Climate change is increasingly considered a problem of 'security', yet what that means remains deeply contested. Behind the rhetoric of 'climate crisis', threats and 'emergencies', UN Security Council members offer profoundly different ideas about what climate change - and security - mean, and what should be done about it. This book brilliantly lays out the hidden or overlooked divergences of interests and perspectives on 'climate security' that are playing out in the world's most central security institution, as it grapples with securing a climate unstable world."Olaf Corry, Professor of Global Security Challenges, Faculty of Social Sciences, School of Politics and International Studies, University of Leeds (United Kingdom)."Security is a contested concept, whose scope and direction are subject to change. The prime value of this volume is the systematic documentation of the dynamics in defining what security is about in reaction to ever dramatic climate change. The book's focus on a somewhat representative sample of states - the members of the Security Council - provides robust evidence that even though many governments remain reluctant to retreat from traditional perceptions of security, there is a large and growing acceptance of the need to adjust priorities in providing security in response to climate change and its consequences."Michael Brzoska, Professor and Senior Research Fellow, IFSH Institute for Peace Research and Security Policy, Universität Hamburg (Germany)."The climate security literature has often been labelled as West-centric with little recognition of knowledge production processes, and different historical, socio-economic, and political exp

  • av Manu L N G Malbrain
    467 - 583,-

    This open access book, published by Springer under the Open Access CC BY 4.0 Licence in collaboration with the International Fluid Academy (IFA, www.fluidacademy.org), explores rationalized intravenous fluid therapy for critically ill patients. Despite being commonly prescribed in inpatient settings, intravenous fluids are often administered without evidence-based guidelines, neglecting essential considerations such as the fact they are drugs, that need proper dosing, duration, indications, contraindications, side effects, and de-escalation. This book fills this knowledge gap. Each chapter starts with a clinical vignette and a related question, followed by a concise summary abstract, key learning points, main text, and a conclusion that addresses the clinical question and provides relevant take-home messages. Additionally, every chapter includes an IFA commentary referencing the latest literature and evidence. The book begins with an introductory chapter that provides definitions and terminology, followed by four sections. The first section covers the fundamentals of intravenous fluid therapy, including fluid compartments in sick patients, fluid bolus dynamics, heart-lung interactions, fluid challenge, fluid responsiveness, arterial blood gas analysis based on traditional and Stewart concepts, and electrolyte physiology relevant to clinical issues. The second section discusses commercially available intravenous fluids, while the third section focuses on fluid therapy in specific clinical situations. The final section introduces the concepts of fluid stewardship and appropriate fluid prescription. Aligned with the International Fluid Academy's mission to enhance education and promote research on fluid management and monitoring, ultimately improving patient survival rates, this book contributes significantly to establishing fluid stewardship at the bedside. It provides valuable support for physicians, nurses, pharmacists, and healthcare professionals across various clinical disciplines working in emergency rooms, operating rooms, or intensive care units, aiding their everyday clinical practice.

  • Spar 16%
    - Structure, Function, and Plasticity
    av Alberto A Rasia-Filho
    1 913,-

    This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system. The density, shape, and function of spines may indicate the cellular connectivity and synaptic plasticity in normal and pathological conditions. This field has undergone dramatic advances in terms of techniques and experimental findings from in vitro to in vivo data, from animal models to human neurons, and computational models using artificial intelligence. To address these cutting-edge findings, the book provides state-of-the-art, comprehensive coverage with chapters written by the leading international researchers in the field. The authors consider the multiple implications for the study of dendritic spines with broad implications in the neurosciences and related areas.

  • av Vikas Prasad
    467 - 583,-

    This open access book is written by world-renowned experts on radiomolecular precision oncology to celebrate the work, life, principles and ideology of Richard P Baum.It includes commentaries, reviews and some thought provoking novel ideas on radionuclide precision oncology, covering topics such as various aspects of theranostics and molecular radiotherapy like radiolabeled peptides, radiolabeled antibodies, dosimetry, and quality control as well as the diagnosis and treatment of specific tumor types. Featuring contributions by biologists, physicists, chemists, mathematicians, geneticists, and physicians from a range of specialties, this Festschrift is highly interdisciplinary and will be a valuable resource for future precision oncologists.

  • - Limits of Pure Dynamic Programming
    av Stasys Jukna
    525,-

    This book presents an enticing introduction to tropical circuits and their use as a rigorous mathematical model for dynamic programming (DP), which is one of the most fundamental algorithmic paradigms for solving combinatorial, discrete optimization problems. In DP, an optimization problem is broken up into smaller subproblems that are solved recursively. Many classical DP algorithms are pure in that they only use the basic (min, +) or (max, +) operations in their recursion equations. In tropical circuits, these operations are used as gates. Thanks to the rigorous combinatorial nature of tropical circuits, elements from the Boolean and arithmetic circuit complexity can be used to obtain lower bounds for tropical circuits, which play a crucial role in understanding the limitations and capabilities of these computational models. This book aims to offer a toolbox for proving lower bounds on the size of tropical circuits.In this work, the reader will find lower-bound ideas and methods that have emerged in the last few years, with detailed proofs. Largely self-contained, this book is meant to be approachable by graduate students in mathematics and computer science with a special interest in circuit complexity.

  • - Efficient Consumer Response (Ecr) in Konsumg Ternetzen
    av Dieter Ahlert
    693,-

    Kooperationen und Verikalisierung in der Konsumgüterdistribution: Die kundenorientierte Neugestaltung des Wertschöpfungsprozeß-Management durch ECR-Kooperationen: D. Ahlert, S. Borchert: Das Beziehungsgeflecht zwischen vertikalem Marketing und der kundenorientierten Neugestaltung von Wertschöpfungsketten.- Die Implementierung des Total Quality Management in ECR-Kooperationen.- Die Situation in der deutschen Lebensmittelbranche als Initialbranche für wertschöpfungsprozeßverändernde ECR-Kooperationen.- Die Ausgestaltung des ECR-Konzeptes als wertschöpfungskettenverändernde Kooperation in der Lebensmitteldistribution.- Zum Status quo des ECR-Konzeptes in der Praxis der Konsumgüterdistribution: H. Meffert: Trends im Konsumentenverhalten - Implikationen für Efficient Consumer Response.- M. Großweischede: Category Management aus Sicht der Lieferanten des Lebensmitteleinzelhandels - Grundlagen und ausgewählte Ergebnisse einer empirischen Studie.- H. Wiezorek: ECR - eine gemeinsame Aufgabe von Hersteller und Handel.- G. Wagener: ECR und die Enabling Technologies - EAN-Standards in Kommunikation und Logistik.- F. Speer: Category Management: Vom verbraucherorientierten Ansatz zum Equity Management.- K. Eierhoff: Efficient Consumer Response (ECR) - ein neuer Weg in der Kooperation zwischen Industrie und Handel.- U. Kalmbach: ECR - Positive Erfahrungen dargestellt am Beispiel der REWE AG.- F. Bruin: Efficient Consumer Response bei Albert Heijn - The State of the Art.- H. Milde: Category Management aus der Perspektive eines Marktforschungsinstitutes.- M. Kaldik: Dienstleistungen eines Marktforschungsinstituts im Rahmen einer Catergory-Management-Kooperation zwischen Hersteller und Händler.- S. Marlow, J. Mebus: Trading Information Exchange - Creating the Intelligent Supply Chain.

  • Spar 15%
    - Practical Manual for Patient Management
    av Paul Clift
    1 451,-

    This book provides a concise, practically applicable guide to the management of patients born with a univentricular heart defect. It describes the anatomy and epidemiology of the univentricular heart, while guidance is provided on how to manage both fetal and neonatal patients with this defect, as well as those in later childhood and adulthood. The utilization of the Fontan operation for patients with a univentricular heart is described in detail. Management of early and late Fontan failure is also discussed, and the pregnant patient is also described, enabling the reader to develop a deep understanding of how to manage these patients in their daily practice. Univentricular Congenital Heart Defects: Practical Manual for Patient Management comprehensively reviews the management of univentricular heart defects and the use of Fontan-type surgery. It is a valuable resource for the experienced practitioner seeking a manual on the latest available techniques and for trainees who want to develop a thorough understanding of how to manage patients with these congenital heart defects.

  • - Die Lage einer Wohnung und eines Wohngebäudes
    av Georg Conditt Sokratis Dimitriou
    943,-

  • av Tanya M Peres
    583,-

    This volume presents an overview of methodologies to identify and study foodways in the archaeological record. It also includes definitions, information, and examples for students and professionals to understand the basic analytical approaches, methods, and themes critical to archaeological studies of foodways. One of the main goals of this book is to show that foodways can help us better understand many aspects of a culture and can be studied from the material culture recovered from archaeological sites. It is important to stress that foodways are, and should be, studied by more than zooarchaeologists and paleoethnobotanists. Foodways encompass the biological and cultural need for sustenance, and thus are a research area that incorporates a multitude of artifact types, analytical specialties, and research questions.Foodways are a tangled web of ideas and behaviors that structure diet, subsistence strategies, cuisines, and the use of food to express identity. While foodstuffs are primary components to foodways, the consumption of material foods is inherently social. Food, dishes, and cuisines are expressions of the people, culture, and time in which they are created. Foodways Archaeology is devoted specifically to the archaeological study of the intersection of food, culture, history, and traditions as viewed in the archaeological record.

  • Spar 14%
    - Indigenous Empowerment and Community Development Through World Heritage
    av Geneviève Susemihl
    1 335,-

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