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Subcellular: Response-Field Dynamics in the Auditory Pathway; D.A. Depireux, et al. Rapid Categorization of Extrafoveal Natural Images: Implications for Biological Models;M. Fabre-Thorpe, et al. Cortical Activity Pattern in Complex Tasks; F. Frisone, et al. Cellular: Resolving the Paradoxical Effect of Activity on Synapse Elimination; M.J. Barber, J.W. Lichtman. Cellular Mechanisms of Calcium Elevation Involved in Long Term Memory; K.T. Blackwell, et al. Temporal Characteristics of V1 Cells Arising from Synaptic Depression; F.S. Chance, et al. Network: An Oscillating Cortical Network Model of Sensory-Motor Timing and Coordination; B. Baird. Pattern-Generator-Driven Development in Self-Organizing Models; J.A. Bednar, R. Miikkulainen. Systems: Finite Element Decomposition of Human Neocortex; D.A. Batte, et al. Path Integration in the Rat Head-Direction Circuit; H.T. Blair, et al. Methodology: The Paperless Laboratory: An Integrated Environment for Data Acquisition, Analysis, Archiving, and Collaboration; T.D. Coates, Jr. The Qualitative Reasoning Neuron: A New Approach to Modeling in Computational Neuroscience; J.L. Krichmar, et al. 93 Additional Articles. Index.

Flavonoids in the Living System: An Introduction; J.A.Manthey, B.S. Buslig. Flavonoids and Arbucular-Mycorrhizal Fungi; H. Vierheilig, et al the Role of Glycosylation in Flavonol-Induced Pollen Germination; L.P. Taylor, et al. Expression of Genes for Enzymes of the Flavonoid Biosynthetic Pathway in the Early Stages of the Rhizobium-Legume Symbiosis; H.I. McKhann, et al. Prospects for the Metabolic Engineering of Bioactive Flavonoids and Related Phenylpropanoid Compounds; R.A. Dixon, et al. Flavonoid Accumulation in Tissue and Cell Culture; Studies in Citrus and other Plant Species; M.A. Berhow. Flavonoids of the Orange Subfamily Aurantioideae; J.A. Manthey, K. Grohmann. Citrus Flavonoids: A Review of Past Biological Activity Against Disease: Discovery of New Flavonoids from Dancy Tangerine Cold Pressed Peel Oil Solids and Leaves; A. Montanari, et al. Differentiation of Soy Sauce Types by HPLC Profile Pattern Recognition: Isolation of Novel Isoflavones; E. Kinoshita, et al. Induction of Oxidative Stress by Redox Active Flavonoids; W.F. Hodnick, et al. Flavonoids in Foods as in Vitro and in Vivo Antioxidants; J.A. Vinson. 7 Additional Chapters. Index.

Signalling and Communication: An Introduction to Section 1; R. Paton. Some Aspects of Gap Junction Dynamics in Embryonic Systems; S. Baigent, et al. Real Time Processing of Nerve Signals for Controlling a Limb Prostheses; M. Bodgan, W. Rosentiel. Stimulus-Secretion Coupling in Pancreatic beta-Cells Explained by Chay's Store-Operated Model; T.R. Chay. Towards Computational Models of Chemotaxis in Escherichia Coli; L. Clarke, R.C. Paton. Three Modes of Calcium-Induced Calcium Release (CICR) in Neurons; D.D. Friel. Theta-Neuron, a One Dimensional Spiking Model that Reproduces in Vitro and in Vivo Spiking Characteristics of Cortical Neurons; B.S. Gutkin, G.B. Ermentrout. Computation and Information: An Introduction to Section 2; R. Paton. Morphomechanical Feedback in Embryonic Development; L.V. Beloussov. Information Processing in Computational Tissues;M.H. Butler, et al. Semiotics of Complex Systems: A Hierarchical Notation for the Mathematical Structure of a Single Cell; J.L.R. Chandler. Localization and Nonlocality in Computation; R. Cottam, et al. Mining the Gene Expression Matrix: Inferring Gene Relationships from Large Scale Gene Expression Data; P. D'haeseleer, et al. Epilogue-Concluding Discussions; M. Holcombe. 18 Additional Chapters. Index.

Sodium (Na+) Transport and Fluid Clearance Across the Normal and Injured Lungs: Regulation of the Sodium Pump in Hyperoxic Lung Injury; D.H. Ingbar, et al. Lung Edema Clearance During Hyperoxic Lung Injury; J.I. Sznajder, K.M. Ridge. Role of the Pulmonary Surfactant in the Pathogenesis and Treatment of ARDS: Host Defense Capacities of Pulmonary Surfactant; U. Pison, S. Pietschmann. Alterations of Pulmonary Surfactant in ARDS-Pathogenic Role and Therapeutic Perspectives; A. Gunther, et al. Mechanisms and Modification of Acute and Chronic Lung Injury: Gene Therapy for the Acute Respiratory Distress Syndrome; P. Factor. The Use of Recombinant Antioxidants in Neonatal Respiratory Distress Syndrome; J.M. Davis. Ventilatory Strategies for the Management of Acute Respiratory Distress Syndrome (ARDS): The Use of PEEP in the Treatment of ARDS; J. Villar. Tracheal Gas Insufflation; A. Nahum. Nitric Oxide: Friend and Foe: Mechanisms of Nitric Oxide Induced Injury to the Alveolar Epithelium; S. Zhu, et al. Macrophage Killing of Mycoplasmas: Involvement of Surfactant Protein A and Nitric Oxide; J.M. Hickman-Davis, et al. Health Care Legislation: Health and Science Legislation in the United States; W.J. Martin, II. 39 Additional Articles. Index.

Cellular Mechanisms Involved in the Modulation of the Immune System by Drugs of Abuse; S.L. Chang, et al. Immunomodulation of Macrophage Functions by Opioids; R. Gomez-Flores, R.J. Weber. Morphine Accelerates the Progression of Sepsis in an Experimental Sepsis Model; S. Roy, et al. Morphine Depresses Macrophage Numbers and Function in Mouse Spleens; T.K. Eisenstein, et al. Morphine Depresses Macrophage Numbers and Function in Mouse Spleens; T.K. Eisenstein, et al. Centrally-Mediated Opioid-Induced Immunosupression: Elucidation of Sympathetic Nervous System Involvement; W.J. Brinkman, et al. The Expression of Interleukin-1beta Converting Enzyme (ICE) in Rat is Decreased Following Chronic Exposure to Morphine; Gao-de Wu, et al. Opioid Receptor Gene Expression in the Porcine Immune System; M.S. Pampusch, et al. The Effects of Interaction Between Morphine and Interleukin-1 on the Immune Response; S.L. Chang, et al. Morphine Alters the Immune Response to Influenza Virus Infection in Lewis Rats; M.E. Coussons-Read, et al. Orphan Opioid Receptor Oligonucleotide Inhibit HIV-1 Expression in Human Brain Cells; C.C. Chao, et al. Opiate Effects on in Vitro Human Retroviral Infection; S.B.Nyland, et al. FIV: A Lentivirus Model for Opiate Effects on Disease; J.-N. Billaud, T.R. Phillips. 21 Additional Articles. Index.

Keynote Adress. Genetic Predisposition and Kindling Susceptibility in Primates; J.A. Wada. Developmental Patterns. Idiosyncrasies of Limbic Kindling in Developing Rats; K.Z. Haas, et al. Long-Term Effects of Kindling on Learning and Memory in the Developing Brain; M. Sarkisian, et al. Electrophysiological Mechanisms. Long-Lasting Prolongation of NMDA Channel Openings after Kindling; I. Mody, D.N. Lieberman. Morphological and Anatomical Mechanisms. Role of Rhinencephalic Networks in Early Stage Kindling; J.L. Burchfiel. Synaptic Pharmacology and Neurochemistry of Kindling. Regionally Specific Changes in Glatamate and GABAA Receptors, PKC Isozymes, and Ionic Channels in Kindling Epileptogenesis of the Hippocampus of the Rat; F.H. Lopes da Silva, et al. Behavioral Effects of Kindling. Amygdala Kindling and Rodent Anxiety; R. Adamec. Drugs and Kindling. Protective Effect of Brain-Derived Neurotrophic Factor in Hippocampal Kindling; S. Reybiel. Clinical Implications of Kindling. The Syndrome of Mesial Temporal Lobe Epilepsy: A Role for Kindling; J. Engel. 27 additional articles. Index.

Ocular Surface, Lids, Tears: The Evolution of Lid Margin Changes in Blepharitis; A.J. Bron, J.M. Tiffany. Corneal Transplantation and Eye Banking: Stromal Hydrodelamination Technique in Deep Lamellar Keratoplasty with Complete Removal of Pathologic Stroma; J.Sugita. Corneal Stroma and Endothelium: An Update on Corneal Hydration Control; J. Fischbarg, D.M. Maurice. Refractive Surgery I: Corneal Tattooing to Treat Glare Symptoms Following Radial Keratotomy; G.J. Florakis et al. Molecular Biology, Cellular Biology, and Genetics: Wound Healing Modulators in Tear Fluid T. Tervo, M. Vesaluoma. Contact Lenses: The Effect of Contact Lenses on the Conjunctiva P.C. Donshik. Microbial Keratitis-Viral: The Biology and Pathology of Varicella Zoster Virus in the Ganglion; T.J. Liesegang. Keratoconus: The Case for Eye Rubbing as the Major Cause of Keratoconus; J.H. Krachmer. Non-Microbial Keratitis and Immunology: Abstracts of Conference Presentations. World Corneal Health: Childhood Keratitis: Epidemiological and Microbiological Study; A. Panda et al. Microbial Keratitis-Non-Viral: Refractive Surgery II: 38 additional articles. Index.

Sensorialities: Information Extraction and Perceptual Grouping in the Auditory System; B.C.J. Moore. Ultrasonic Techniques for Environment Perception; D. Dotti. The Vestibular System; E. Mira. Perception and Integration: Integration and Storage of Sensory Motor Information: Computation in the Cerebellum; E. D¿Angelo. Field Computation and Sensory Fusion; V. Sanguineti, et al. Panel Summary-Plasticity and Reconfigurability in Sensory Systems; S. Vallerga, et al. Perception and Decision: Solving by Redundancy and Misunderstanding by Simplification; W. Gerbino. Perception for Decision or Decision for Perception?;B.Y. Zavidovique. Perception and Action: Integrating Reflexes and Voluntary Behaviors: Coordination and Adaptation Controls in Man; G.M. Gauthier, et al. Motion Perception as an Area Process; Y. Hermush, Y. Yeshurun. Perception and Representation: Representation and Integration of Multiple Knowledge Sources: Issues and Questions; C. Castelfranchi. Symbolic, Conceptual and Subconceptual Representations; P. Gardenfors. Percepton and Communication: Picture Icon and Word Icon; J.P. Rossi, G. Querrioux-Coulombier. Panel Summary. Characters, Pixels, and Phonemes; S. Levialdi, et al. 4 Additional Articles. 4 Panel Summaries. Index.

Preface; A. Altman, Y. Waisel. Diversity of Roots: The Place of Roots in Plant Development and the Diversity of Root Types; P.W. Barlow, B. Palma. Induction of Roots and Their Development: Indissociable Chief Actors in the Inductive Phase of Adventitious Rooting; T. Gaspar et al. Hormonal Control of Root Induction and Development: Increased Induction of Adventitious Rooting via Slow Release Auxins and Elicitors; van der Krieken et al. Molecular Biology of Root Development: Auxin Induced Gene Expression During Rooting of Loblolly Pine Stem Cuttings; B. Goldfarb et al. Ecological Aspects of Root Development: Shootborne Roots: An Adaptive Organ in Sand Dunes; A. Danin. Applied Aspects of Root Development: Relations between Early Root Growth and Flower Yield of Clonal Rose Rootstocks; D.P. de Vries, L.A.M. Dubois. Root Products: Insane Roots and Twisted Carrots: Physiology and Biochemistry of Root Specific Metabolites; H.E. Flores. Models and Methods for Root Study: Morphological Structured Model for Hairy Root Culture; I. Berzin et al. Concluding Remarks: A 1996 Overview of the Research Interests from the Jerusalem Symposium T. Gaspar. 71 additional articles. Index.

Introduction: Serpins: From the Way It Was to the Way It Is; J. Travis. Serpins: A Mechanistic Class of Their Own; S.R. Stone, et al. Coagulation: Antithrombin-A Bloody Important Serpin; I. Björk, S.T. Olson. Heparin Cofactor II; D.M. Tollefsen. Neurobiology and Cancer: Regulation of Neurons and Astrocytes by Thrombin and Protease Nexin-l: Relationship to Brain Injury; D.D. Cunningham, F.M. Donovan. Maspin: A Tumor Suppressing Serpin; R. Sager, et al.. Fibrinolysis: The Role of Reactive-Center Loop Mobility in the Serpin Inhibitory Mechanism; D.A. Lawrence. Substrate Specificity of Tissue Type Plasminogen Activator; E.L. Madison. Development and Reproduction: Biology of Progesterone-Induced Uterine Serpins; P.J. Hansen, W.-J. Liu. Serpins from an Insect, Manduca sexta; M.R. Kanost, H. Jiang. Inflammation: Serpins and Programmed Cell Death; G.S. Salvesen. Noninhibitor Serpins: Structure-Function Studies on PEDF: A Noninhibitory Serpin with Neurotropic Activity; S.P. Becerra. Abstracts: Coagulation, Neurobiology and Cancer. Fibrinolysis, Development and Reproduction. Inflammation and Noninhibitor Serpins. 10 Additional Articles. Index.

Clinical neuropsychology for infants and young children is an emerging field that contains as much promise as it does perplexing practical and theoretical questions. Infant and Early Childhood Neuropsychology is a groundbreaking study that provides an assessment framework and diagnostic clues for clinicians and researchers, as well as the first documentation and description of this new field for students. The clearly written text translates neuroanatomic issues into clinical applications for professionals charged with making neuropsychological assessments of infants and young children.

Introduction. Mono(ADP-ribosyl)Transferases and Related Enzymes: Emerging Gene Families; F. Koch-Nolte, F. Haag. Mono-ADP-ribosylation in Prokaryotes. Crystal Structure of Diphtheria Toxin Bound to Nicotinamide Adenine Dinucleotide; C.E. Bell, D. Eisenberg. Molecular Approaches to Eukaryotic Mono(ADP-ribosyl)Transferases. Sequence and Structural Links Between Distant ADp-ribosyltransferase Families; F. Bazan, F. Koch-Nolte. Moni(ADP-ribosyl)Transferases in the Immune System. Regulation of Cytotoxic T Cell Functions by a GPI-anchored Ecto-ADP-ribosyltransferase; J. Wang, et al. Mono-ADP-ribosylation in Other Animal Tissues. An ADP-Ribosyltransferase from Bovine Erythrocytes Apparently Specific for Cysteine Residues; S. van Heyningen, B. Saxty. Physiology of GPI-Anchored Proteins. Cell Surface Dynamics of GPI-anchored Proteins; F.R. Maxfield, S. Mayor. Relationship of ADP-Ribosyltransferases to NAD+ Glycohydrolases and ADP-ribosyl Cyclases. ADp-Ribose in Glycation and Glycoxidation Reactions; E.L. Jacobson, et al. Special Lecture Commemorating the Retirement of Professor Heinz-Günter Thiele. Appendix. 28 Additional Lectures. 24 Poster Reports. Index.

Evaluating the Statistical Significance of Multiple Distinct Local Alignments; S.F. Altscul. Hidden Markov Models for Human Genes: Periodic Patterns in Exon Sequence; S. Brunak. Identification of Muscle-Specific Transcriptional Regulatory Regions; J.W. Fickett. A Systematic Analysis of Gene Functions by the Metabolic Pathway Database; M. Kanehisa. Polymer Dynamics of DNA, Chromatin and Chromosomes; J. Langowski. Is Whole Human Genome Sequencing Feasible?; E.W. Myers. Sequence patterns Diagnostic of Structure and Function; T.F. Smith. Recognizing Functional Domains in Biological Sequences; G.D. Stormo. Stochastic Modelling in Molecular Genetics; P. Tautu. The Integrated Genomic Database (IGD): Enhancing the Productivity of Gene Mapping Projects; S.P. Bryant. Error Analysis of Genetic Linkage Data; R. Cottingham. Managing Accelerating Data Growth in the Genome Database; K.H. Fasman. Advances in Statistical Methods for Linkage Analysis; D.E. Weeks. Exploring Heterogeneous Molecular Biology Databases in the Context of the Object-Protocol Model; V.M. Markowitz. Comprehensive Genome Information Systems; O. Ritter. Visualizing the Genome; D.B. Searls. Data Management for Ligand-Based Drug Design; K. Aberer. 7 Additional Articles. Index.