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This contributed volume considers the emergence of coworking as centered in labor issues. More specifically, its chapters consider it as a coping mechanism in the worldwide rise of independent modes of work (i.e., self-employment) that leaves more and more workers exposed to precarity as they must organize and manage their own labor. Grounded in this perspective, this volume aims to understand the transformative social and political potentials emerging through coworking as a social and spatial practice. There is a distinct lack of discussion within coworking research on the emancipatory potentials of coworking--and if it is discussed, more cautionary views prevail, highlighting the ambivalence of coworking spaces both as a space of alternative economic practices and as integrated into market economies. The aims of this collection are twofold: First, it aims to make visible the plurality of existing practices around shared resources in coworking and the assemblages of human and non-human actors as agents of change associated with coworking and the re-organization of work and labor power. And second, it aims to develop a more emancipatory narrative for coworking and the role of coworking spaces for workers but also the different spatial contexts in which these spaces are situated. A narrative that does not emphasize entrepreneurship or coworking as the epitome of the 'neoliberal entrepreneurial self' as in the dominant interpretations in the current research, but rather one that centers coworking in the creation of meaningful, careful social relationships, supporting empathy and an ethics that recognizes mutual interdependencies and builds a foundation for social change. So, it is about alternative narratives, emancipation politics and the wider social role that coworking spaces might play in neighborhoods, cities or beyond because they are crucial contexts for the formation and maintenance of social relations. With this specific direction, this collection aims to bring coworking research into a fruitful dialog with other research fields-such as sociology of work, feminist perspectives on care, alternative and diverse economies, "post-capitalist" transformation, critical geography, positioning coworking within a range of progressive alternatives in the articulation of economic and social relationships.

Sleep diseases and cases are both very common (such as sleep respiratory disturbances) and rare (such as narcolepsy), with increasing and alarming prevalence worldwide. As diagnosis is always performed by physicians, physiotherapists often receive the patients referred by other health practitioners.This engaging book focuses on a compilation of case reports and clinical scenarios collected over the years. It intends to show the practical management of different cases in treating sleep disorders by physiotherapists. The reader will have a chance to understand how, in clinical practice, physiotherapists from different countries treat sleep issues, either in conjunction or not with other health professions.Written by worldwide experts, the 30 instructive chapters present the practice of sleep and physical therapy around the globe, as well as the integration of sleep as a imperative topic in health promotion and well-being. They also intend to describe the anamnesis, the clinical history, rationale and process for the physiotherapeutic treatment, patient-centered, and with an interdisciplinary approach. The reader will be able to tie up loose ends of the clinical picture and to connect with the theoretical knowledge, understanding the evidence-based practice in each of the clinical case, thus having the insight to start thinking as a sleep physiotherapist. As the contemporary world is always changing, so is physical therapy on behalf of health in these lightning times.

This open access book on thyroid surgery has been authored by an international team of contributors who present a comprehensive understanding of both benign and malignant thyroid disorders. It also outlines an interdisciplinary approach to their surgical management that reflects the latest changes in surgical techniques. The book reviews the most up-to-date literature available on thyroid surgery and presents it in a concise manner for use in clinical practice. For each thyroid disorder, the book covers etiology, clinical manifestations, diagnostic and localization procedures, as well as surgical and non-surgical treatment options. The operating techniques and postoperative management are explained in detail, while the benefits, risks, controversial issues, and cost-effectiveness of each approach are reviewed. To aid in the understanding of complex information, the book features drawings and photographs. Written in an easy-to-understand style, the book includes tablesand diagrams that highlight best practices and current guidelines, as well as self-assessment material at the end of each section. It serves as an ideal resource for all levels of surgical experience, from a practical reference for endocrine surgeons to a perfect companion for students and residents.

Brain Tumors Hodgkin and non-Hodgkin lymphoma Oral squamous cell carcinoma Testicular cancer Head and neck tumors Prostate cancer Carcinoma of unknown primary Malignant melanoma Thyroid carcinomas Metastatic bone disease Lung cancer Renal cell and urothelial cancer Pancreatic cancer Endocrine/ neuroendocrine tumors Hepatobiliary tumors Breast cancer Colorectal carcinomas Ovarian cancer

I. The Cauchy Problem.- II. Qualitative Theory of Second Order Linear Partial Differential Equations.- Author Index.

This book provides a comprehensive overview of the molecular basis of developmental and stem cell regulation. It revisits some of the classical models of developmental biology and puts them in context with the findings of modern stem cell research and developmental biology. Biomedical research is embarking on a new era due to new tools, which are exemplified by stem cell technologies, single-cell transcriptome analysis, and live imaging at a single-cell resolution. Publications based on cutting-edge technologies do often not provide the readers with deep biological backgrounds. This causes the risk that precious data are reduced to highly specific descriptions without sufficient biological contexts.Contemporary developmental biology on the other hand as written in many textbooks, is to a significant extent based on conceptions backdated many decades ago, and is not necessarily supported by recent findings. Yet, the prevailing classical notions tend to mislead modern biomedical researches.This book not only presents current models for developmental processes but also reinterprets and re-evaluates classic observations, thus linking classical and modern worlds of developmental biology. Spanning from molecular mechanisms to highly embryological matters it provides a bridge between these different disciplines.Written for advanced students of developmental and stem cell biology, researchers and teaching scholars, this book provides a new road map to modern developmental biology and stem cell biology.

Krankheiten der Leber.- Akute und chronische Virushepatitiden.- Bakterielle und parasitäre Leberkrankheiten.- Leberkrankheiten bei Aids.- Autoimmunhepatitiden und Overlap syndrome.- Primär-biliäre Zirrhose, primär-sklerosierende Cholangitis und "Vanishing-bile-duct"-Syndrom.- Hämochromatose (hereditäre Hämochromatose; sekundäre Eisenüberladungssyndrome).- Morbus Wilson.- ?1-Antitrypsinmangel.- Zystische Fibröse.- Primäre Stoffwechsel- und Speicherkrankheiten.- Porphyrien.- Hyperbilirubinsyndrome.- Medikamentöse/toxische Leberschäden und alkoholische Leberkrankheiten.- Nichtalkoholische Steatohepatitis (NASH).- A Vaskuläre Lebererkrankungen.- B Graft-versus-Host-Krankheit der Leber.- Pulmonale Komplikationen bei Leberkrankheiten.- Leber- und Systemerkrankungen.- Leber: Wechselwirkungen mit dem hämatopoetischen System.- Hep atop athien in der Schwangerschaft.- Krankheiten der Gallenblase und Gallengänge.- Cholezystolithiasis und Choledocholithiasis.- Cholezystitis.- Cholangitis.- Anomalien der Gallenwege und Strikturen.- Sphinkter-Oddi-Dysfunktion.- Aids-assoziierte Cholangitis.- Leberzirrhose und Komplikationen.- Leberzirrhose.- Leberzirrhose und portale Hypertension.- Leberzirrhose und Aszites.- Hepatische Enzephalopathie.- Leberzirrhose und spontan-bakterielle Peritonitis.- Leberzirrhose und Nierenfunktionsstörungen.- Leberzirrhose und Gerinnungsstörungen.- Tumoren der Leber, Gallenblase und Gallenwege.- Benigne Tumoren der Leber, Gallenblase und Gallenwege.- Maligne Tumoren der Leber und Gallenwege.- Lebermetastasen.- Leberveränderungen bei hämatologischen Neoplasien.- Akutes Leberversagen und Transplantation.- Akutes fulminantes Leberversagen.- Indikationen zur Lebertransplantation.- Vorbereitung zur Lebertransplantation.- Intra- und postoperatives Management bei Lebertransplantation.- Nachsorge bei Lebertransplantation.- Pharmakotherapie und Ernährung.- Pharmakotherapie bei vorgeschädigter Leber.- Leber und Ernährung.- Sozialmedizinische Beurteilung bei Leber und Gallekrankheiten.- Sozialmedizinische Aspekte.

This book complements the authors' monograph Cellular Automata and Groups [CAG] (Springer Monographs in Mathematics). It consists of more than 600 fully solved exercises in symbolic dynamics and geometric group theory with connections to geometry and topology, ring and module theory, automata theory and theoretical computer science. Each solution is detailed and entirely self-contained, in the sense that it only requires a standard undergraduate-level background in abstract algebra and general topology, together with results established in [CAG] and in previous exercises. It includes a wealth of gradually worked out examples and counterexamples presented here for the first time in textbook form. Additional comments provide some historical and bibliographical information, including an account of related recent developments and suggestions for further reading. The eight-chapter division from [CAG] is maintained. Each chapter begins with a summary of the main definitions and results contained in the corresponding chapter of [CAG]. The book is suitable either for classroom or individual use.Foreword by Rostislav I. Grigorchuk

Historically, Donald Trump will be remembered as the first American president to be impeached twice and indicted. He fed the grotesque myth that the election was stolen and summoned his supporters to storm Congress on 6 January 2021 in a bid to thwart the certification of Joe Biden's U.S. presidential election victory. This volume vividly recounts the dramatic narrative of the January 6 Coup in America and how close we came to losing U.S. democracy. For anyone seeking a comprehensive and multidisciplinary global overview of democracy, an astute analysis of the forces that drive the dominance of the (neo)liberal paradigm of the last decades should look no further than this volume. Yet the volume takes the issue further by vigorously documenting the decline of the U.S. treaty process (America's dysfunctional diplomacy and the doctrine of unpredictability). There is an urgent need for a massive infusion of strategic support for democracy in the United States. Because come 2024or thereafter an unfinished work might drag American democracy to a dangerous inflection point. Trump (who has a complete hold on the Republican party, still has a stranglehold on the MAGA base no matter what he does, was instrumental to the breaking of U.S. diplomacy. Undermining the democratic legitimacy of International Law adversely affected U.S. foreign policy. Some federal and lower courts in the judiciary of the United States pose a real threat to Americans' democracy as well. To that end, when 'the principle of truth' loses its relevance and meaning as benchmarks for appraisals and decisions, and becomes a harmful tool for willful propaganda. Everybody should be worried about U.S. democracy. A "real" crisis is coming! U.S. Democracy is at a breaking point. Like a giant modern mirror standing behind democracy itself, this book is a citizen's guide to saving U.S. Democracy. Expertly drawn on global and regional examples and current literature, the volume closes agap in the multidisciplinary field. Quite useful as a valuable resource as it helps us understand the shifting Trump agenda in diverse areas. Essential reference across a range of subjects, bringing together contributions from scholars, and policymakers alike. This extraordinarily well-researched and practically crafted, culture-inclusive text could not be more relevant or timelier. It is a must for everyone. This volume will help to shape the political landscape of the 21st century and will remain a vital source of inspiration for modern-day scholars and political activists.

The technical measurement of individual parameters in an area as complex as music and song has achieved acceptance only in recent years. However important objective parameters of normal voice development may be, they are especially so when patholo- cal deviations have to be recognised and defined. It is nevertheless also possible to a certain extent to describe different qualities of normal voice development in terms of measurable parameters. Hormonal changes have a considerable influence on the ph- ical and mental development of boys and girls. The extent to which this influence affects voice development in the two sexes will be made clear in this work through the observation of a number of parameters. I hope that this will stimulate further investigations of this topic. Possible interesting topics for further research are emphasised in the text. Working with adolescents and documenting their vocal dev- opment has given me a lot of pleasure. Colleagues with different medical specialities have supported me in this task. The practical significance of this work has shown itself in the way the results obtained (the graphs and tables) are used today by laryngo- gists, phoniatricians and music teachers in their daily work, and vii viii Preface the determination of hormonal levels in the course of puberty has been introduced as a routine in choirs.

This memoir chronicles the journey of an academic, tracing a path from primary school in Zambia to a career in higher education as a mathematician and educational leader. Set against the backdrop of the 20th century, the book explores how early influences and historical events shape an individual's life and professional trajectory. The author shares childhood experiences across three parts of Africa, providing an original perspective as a witness to the post-colonial period. Through personal reflections, the memoir delves into the emergence of ideas and collaborations in mathematics and how these shape career choices. It also offers candid observations on the major changes in British higher education since the 1980s. Intended for a general audience, this book provides a compelling read for anyone interested in the experience of becoming a mathematician, and higher education in general.

The Asian Yearbook of International Economic Law (AYIEL) 2023 addresses the rapidly evolving field of international economic law with a special focus on Asia and the Pacific. This region has long been and remains a major engine of the world economy; at the same time, it is characterized by a host of economies with varying developmental levels, economic policies and legal jurisdictions. The AYIEL 2023 therefore focuses on international economic law, especially on security and industrial policy.

This open-access book brings together international experts who shed new light on the status of social enterprises, benefit corporations and other purpose-driven companies. The respective chapters take a multidisciplinary approach (combining law, philosophy, history, sociology and economics) and provide valuable insights on fostering social entrepreneurship and advancing the common good.In recent years, we have witnessed a significant shift of how business activities are conducted, mainly through the rise of social enterprises. In an effort to target social problems at their roots, social entrepreneurs create organizations that bring transformative social changes by considering, among others, ethical, social, and environmental factors. A variety of social enterprise models are emerging internationally and are proving their vitality and importance.But what does the term ¿social enterprise¿ mean? What are its roots? And how does it work in practice within the legal framework of any country? This handbook attempts to answer these questions from a theoretical, historical, and comparative perspective, bringing together 44 contributions written by 71 expert researchers and practitioners in this field. The first part provides an overview of the social enterprise movement, its evolution, and the different forms entities can take to meet global challenges, overcoming the limits of what governments and states can do. The second part focuses on the emergence of benefit corporations and the growing importance of sustainability and societal values, while also analyzing their different legal forms and adaptation to their regulatory environment. In turn, the last part presents the status quo of purpose-driven companies in 36 developed and emerging economies worldwide.This handbook offers food for thought and guidance for everyone interested in this field. It will benefit practitioners and decision-makers involved in social and community organizations, as well as in international development and, more generally speaking, social sciences and economics.

This peer-reviewed book presents a comprehensive overview of the role space is playing in enabling Latin America to fulfil its developmental aspirations. Following on from the highly acclaimed Parts 1 to 4, it explains how space and its applications can be used to support the development of the full range and diversity of Latin America societies, while being driven by Latin American goals. The Latin American space sector is currently undergoing a phase of rapid and dynamic expansion, with new actors entering the field and with space applications increasingly being used to support the continent's social, economic, and political development. All across Latin America, attention is shifting to space as a fundamental part of the continental development agenda, and the creation of a Latin American space agency is evidence of this. Additionally, while in recent years, significant advances in economic and social development have lifted many of Latin America's people out of poverty, there is still much that needs to be done to fulfil the basic needs of the population and to afford them the dignity they deserve. To this end, space is already being employed in diverse fields of human endeavour to serve Latin America's goals for its future, but there is still a need for further incorporation of space systems and data. This book will appeal to researchers, professionals and students in fields such as space studies, international relations, governance, and social and rural development.

Some Historical and Philosophical Reflections on the Myofibroblast Concept.- Transcriptional Regulation of the Desmin and SM22 Genes in Vascular Smooth Muscle Cells.- Modulation of Myofibroblast and Smooth-Muscle Phenotypes in the Lung.- Role of Platelet-Derived Growth Factors in Angiogenesis and Alveogenesis.- Transforming Growth Factor-? Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis.- Transforming Growth Factor-? Induction of ?-Smooth Muscle Actin is Dependent on the Deformability of the Collagen Matrix.- Signal Transduction Pathways Activated During Fibroblast Contraction of Collagen Matrices.- Extracellular Matrix, Integrins and Focal Adhesions.- What Is New in Mechanical Properties of Tissue-Engineered Organs.- Fibroblast - Cytokine - Extracellular Matrix Interactions in Wound Repair.- Myofibroblastic Differentiation and Extracellular Matrix Deposition in Early Stages of Cholestatic Fibrosis in Rat Liver.- Gene Therapy of Wounds with Growth Factors.- What's New in Human Wound-Healing Myofibroblasts?.- The Myofibroblast in Neoplasia.- The Concept of Organizing Pneumonia.- Endothelial Repair in Atherogenesis.- Glomerulosclerosis: The Role of Interstitial Myofibroblasts in its Progression.- The Myofibroblast as an Inflammatory Cell in Pulmonary Fibrosis.- Cell-Cell and Cell-Matrix Interactions During Breast Cancer Progression.- Hepatocyte Growth Factor Secreted by Human Liver Myofibroblasts Increases Invasiveness of Hepatocellular Carcinoma Cells.- Interplay of Matrix and Myofibroblasts During Hepatic Fibrogenesis.

Kritischer Überblick über Hipparion im Neogen von Rumänien.

This book provides a comprehensive review of the role of molecular imaging in neurodegenerative diseases. A growing field, molecular imaging of neurodegeneration is becoming increasingly relevant with an aging population, and this book serves to provide both an introduction to the concept and background of neurodegeneration and an update on the most recent imaging advances.Throughout, chapters will review current applications of neuroimaging in neurodegenerative disorders, like dementia and movement disorders, and increase knowledge of quantification and semi-quantification methods for neuroimaging. Imaging methods such as PET/CT and PET/MR are covered, as well as more advanced technologies like artificial intelligence algorithms and novel radiotracers. Chapters are also intended to improve competency in reporting and interpretation skills with structured information on current practice. The book concludes with a collection of up to date practice cases for the interpretation of neurodegeneration in nuclear medicine imaging.This is an ideal guide for nuclear medicine physicians, neuroradiologists, neurologists, residents, trainees, and related medical professionals caring for patients with neurodegeneration.

This book focuses on the current status of our understanding of RNA, a key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA, noncoding RNAs, modified nucleosides, and RNA enzymes. The different chapters detail methods to investigate RNA structure and function, the chemistry of modified RNAs, and the latest advances in our understanding of the vast array of biological processes in which RNA is involved.RNA, in one form or another, touches almost everything in a cell. RNA has both structural and catalytic properties. RNA fulfills a broad range of functions. These molecules are no longer seen as passive elements transferring the genetic information from DNA into proteins but regulate the activity of genes during development, cellular differentiation, and changing environments. RNAs are involved in various aspects of cell physiology and disease development. Discoveries of RNA with unexpected diverse functions in healthy and diseased cells, such as the role of RNA as both the source and countermeasure to cancer or severe viral infection, stimulate new trends, passion, and solutions for molecular medicine.In this book, fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, how to determine RNA structure and how to apply RNA in treatment of diseases.This book is an essential resource for researches in academia and industry contributing to the development of new RNA therapeutics. The book is geared toward scientists from the graduate level on up and particularly appeals to active investigators in RNA biology, molecular biology, and biochemistry.

This open access Regional Reader describes population movement circulating within the Mediterranean area, for any reason or from any region, be them European, African, Asian or originating from any of the Mediterranean shores. It showcases a plurality of approaches to and applications of Mediterranean migration, contributing to a regional approach to migration studies, thereby defending this regional approach by scaling Mediterranean migration issues. This book covers a large set of questions related Mediterranean migrations to the migration research agenda, such as: market and economy, politics and policies, super-diversity and intersectionality, media, society, welfare and the environment through five main parts: Geo-political Mediterranean Relations, Governance, Policies and Politics, Mobility drivers and Agency, Cities, History and Social Transformations, and Economy and Labour Markets. This Regional Reader provides an interesting read to scholars, researchers, but also policy makers and civil society organizations' high representatives, international foundations and institutions interested in linking the Mediterranean and migration.

The Lymnaeidae (also known as `pond snails¿) are a species-rich and globally distributed family of freshwater snails, many species of which are known to be hosts of parasitic trematodes (such as the liver fluke, Fasciola hepatica). Written by world-leading experts in the field, this book covers a wealth of topics ranging from the phylogeny and taxonomy of lymnaeid snails to their relationships with helminths and their impact on public and veterinary health. It provides an overview of the species richness, evolution, ecology, biogeography and fossil record of the family. A considerable number of chapters are devoted to the economic and medical importance of lymnaeids, their involvement in the transmission of fascioliasis and other zoonotic diseases. Special chapters deal with the molecular and morphological identification of the Lymnaeidae, their rearing in the laboratory and experimental approaches to their study. This contributed volume is aimed at experts and practitioners in various disciplines: Invertebrate zoology, evolutionary biology, biogeography, aquatic ecology, parasitology, epidemiology and public health. It is also useful for university lecturers, undergraduate and postgraduate students.

1 Zusammenfassung.- Konzept der Studie.- Möglichkeiten und Grenzen der Kombination beider Ansätze.- Ergebnisse.- Sachbilanz Top-down-Ansatz (Momentaufnahme 1991).- Sachbilanz Bottom-up-Ansatz (Bestandsmodell).- Gegenüberstellung der Ergebnisse.- Eingebrachte Problemstoffe.- Trendfortschreibung.- Leitbilder für den Baubereich.- 2 Methodischer Ansatz.- 2.1 Bottom-up-Ansatz: Das Modell des Gebäudebestands.- 2.1.1 Stoffflußrelevante Beschreibung des Bestandes in Nutzungs-und Altersklassen.- 2.1.2 Aufbau des Dynamischen Gebäudebestandsmodells.- 2.1.3 Zustand des Bestands - Alterung von Gebäuden.- 2.2 Top-down-Ansatz.- 2.2.1 Berechnung kumulierter Größen im Top-down-Ansatz.- 2.2.2 Vor-und Nachteile des Top-down-Ansatzes.- 2.2.3 Ergänzende Erläuterungen zur Vorgehensweise und Datenbasis beim Top-down-Ansatz.- 2.3 Methodik und Datenbasis für die Bestimmung der eingebrachten Problemstoffe.- 2.3.1 Vorgehensweise.- 2.3.2 Datenquellen und Datenqualität.- 2.4 Systemgrenzen.- 2.5 Gegenüberstellung des Top-down und Bottom-up-Ansatzes.- 2.6 Sachbilanz.- 2.7 Szenario.- 3 Ergebnisse der Sachbilanz.- 3.1 Bottom-up-Ansatz.- 3.1.1 Stofflager.- 3.1.2 Stoffströme.- 3.1.3 Flächen.- 3.1.4 Energie.- 3.1.5 Emissionen und Umweltindikatoren.- 3.1.6 Kosten.- 3.2 Stoffströme, Energieströme, Luftschadstoffemissionen und Kosten - Top-down-Ansatz.- 3.2.1 Methodik.- 3.2.2 Erstellung der Sachbilanzen.- 3.2.3 Bestimmung jährlich anfallender Mengen an Abfällen aus den Bereichen "Bauen und Wohnen" für verschiedene Jahre, Angaben über weiterverwertete und weiterverwendete Anteile.- 3.2.4 Die Kosten im Sektor "Bauen und Wohnen" im Spiegel der Statistik.- 3.2.5 Zusammenfassung der Ergebnisse.- 3.3 Eingebrachte Problemstoffe.- 3.3.1 Aufgabenstellung.- 3.3.2 Allgemeiner Untersuchungsgang.- 3.3.3 Vorgehensweise und Begrenzungen.- 3.3.4 Stofflisten und Problemstofffrachten.- 3.3.5 Ausgewählte Stoffe.- 3.3.6 Ausgewählte Tätigkeitsbereiche und zugeordnete Problemstoffe.- 3.3.7 Problemstoffe im Bauschutt.- 3.3.8 Zusammenfassung und Kommentar.- 3.4 Bilanzierung und Diskussion der Ergebnisse der Bottom-up und Top-down-Ansätze.- 3.4.1 Stoffströme.- 3.4.2 Energie und Umweltbelastungen.- 3.5 Vergleich mit anderen Studien.- 3.5.1 Stoffströme.- 3.5.2 Kosten.- 3.6 Internationaler Vergleich.- 3.7 Landschafts-und Bodenverbrauch.- 3.7.1 Flächeninanspruchnahme durch Wohnungsbauflächen.- 3.7.2 Katasterdaten.- 3.7.3 Baufertigstellungen und Baugenehmigungen.- 3.7.4 Städtebauliche Strukturtypen und ihr Flächenbedarf.- 4 Szenario.- 4.1 Modellannahmen.- 4.2 Diskussion der Ergebnisse.- 4.3 Kommentar zum Szenario.- 5 Strategische Überlegungen zur Bestandsbewirtschaftung.- 6 Forschungsbedarf.- 6.1 Methodische Probleme.- 6.2 Untersuchungsbereich.- 6.3 Regionale Erfassung.- 6.4 Gebäudebestand.- 6.4.1 Beschreibung der Gebäude.- 6.4.2 Abriß, Entsorgung, Recycling.- 6.5 Externe Kosten.- 6.6 Bautätigkeit und Baukosten.- 6.7 Ökobilanzen von Baustoffen.- 6.8 Problemstoffe.- 6.9 Datenlage.- 7 Ziele, Maßnahmen und Instrumente für eine nachhaltige Entwicklung im Sektor "Bauen und Wohnen".- 7.1 Nachhaltigkeit im Bereich Bauen und Wohnen - Ziele und gegenwärtige Entwicklungstrends.- 7.2 Handlungsfelder für eine nachhaltige Politik im Sektor "Bauen und Wohnen".- 7.3 Perspektiven zur Fortschreibung des Bestands.- Anhang A: GISBAU-Inhaltsstoffe.- Anhang B: BUWAL-Zusatzstoffe.- Anhang C: Problemstoffe im Bauschutt.

I Esophagus.- 1 Squamous Cell Carcinoma of the Esophagus.- Summary.- Epidemiology.- Etiology.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis and Follow-Up.- Future Perspectives.- 2 Adenocarcinoma of the Esophagus.- Summary.- Epidemiology.- Etiology and Pathogenesis.- Symptoms and Clinical Signs.- Diagnosis.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis.- Future Perspectives.- 3 Other Tumors of the Esophagus.- Summary.- Mesenchymal Tumors of the Esophagus.- Endocrine Tumors of the Esophagus.- Lymphoma of the Esophagus.- Secondary Tumors of the Esophagus.- Melanoma of the Esophagus.- II Stomach.- 4 Gastric Cancer.- Summary.- Epidemiology.- Etiology and Pathogenesis.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis.- Follow-Up.- Future Perspectives.- 5 Lymphoma of the Stomach.- Summary.- Epidemiology.- Etiology and Pathogenesis.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis and Follow-Up.- Future Perspectives.- 6 Gastric Tumors Other than Adenocarcinoma and Lymphoma.- Summary.- Epithelial Tumors.- Mesenchymal Tumors of the Stomach.- III Small Intestine.- 7 Neoplasms of the Small Intestine.- Summary.- Epidemiology.- Etiology.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis and Follow-Up.- Future Perspectives.- IV Colon and Rectum.- 8 Colorectal Cancer.- Summary.- Epidemiology.- Etiology and Pathogenesis.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Future Perspectives.- 9 Sporadic Adenomas of the Large Intestine.- Summary.- Epidemiology.- Etiology and Pathogenesis.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Treatment.- Future Perspectives.- 10 Hereditary Polyposis Syndromes.- Summary.- Adenomatous Polyposis Syndromes.- Hamartomatous Polyposis Syndromes.- Juvenile Polyposis Syndrome (JPS).- Hereditary Mixed Polyposis Syndrome (HMPS).- 11 Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome).- Summary.- Epidemiology.- Etiology and Pathogenesis.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis.- Follow-Up.- Future Perspectives.- 12 Colorectal Cancer in Inflammatory Bowel Disease.- Summary.- Epidemiology.- Etiology and Pathogenesis.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis and Follow-Up.- Future Perspectives.- V Anal Canal.- 13 Anal Carcinoma.- Summary.- Epidemiology.- Etiology and Pathogenesis.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis.- Follow-Up.- Future Perspectives.- VI Pancreas.- 14 Neoplastic Lesions of the Pancreas.- Summary.- Adenocarcinoma of the Pancreas.- Cystic Carcinoma of the Pancreas.- Other Tumors.- VII Neuroendocrine Gastro-Entero-Pancreatic Tumors.- 15 Neuroendocrine Gastro-Entero-Pancreatic (GEP) Tumors.- Summary.- Definition.- Classification.- Epidemiology.- Etiology.- General Pathophysiology.- Histopathology.- Molecular Pathogenesis.- Growth Characteristics and Metastatic Spread and Secondary Non-Endocrine Malignancies.- Staging of Endocrine GEP Tumors.- Clinical Entities: Symptoms and Laboratory Findings.- General Aspect of Management.- VIII Biliary System and Papilla of Vater.- 16 Carcinoma of the Gallbladder and Bile Ducts.- Summary.- Epidemiology.- Etiology.- Symptoms and Clinical Signs.- Diagnostics.- Histological Classification and Molecular Genetics.- Staging.- Treatment.- Prognosis and Follow-Up.- Future Perspectives.- 17 Benign Tumors of the Biliary Sys...

This book compiles cross-cultural studies on alienation undertaken by the late Dr. Melvin Seeman, including relevant historical and theoretical contexts and analyses related to the ongoing development of the alienation model and its counterparts in the behavioral sciences. Chapters track the development of this model across a half-century of interdisciplinary research, encompassing various research partnerships over the years.

The book focuses on the modus operandi of the Committee on the Rights of Persons with Disabilities (CRPD Committee), the Convention on the Rights of Persons with Disabilities (CRPD) monitoring body, and its main tasks, namely monitoring functions and interpreting the CRPD provisions. Unlike other doctrinal contributions, it analyses all aspects of the CRPD Committee, including those of an institutional nature (membership, sessions, methods of voting, relationships with other organs, and others).The target audience of the book is composed of academics and students of international human rights law. Furthermore, it serves as a guide for civil servants, NGOs, DPOs, practitioners and other stakeholders involved in implementing disability rights.

Epigenetic alterations are heritable changes that play a key role in human development and tissue-specific gene expression patterns. These changes can lead to alterations involved in tumor formation, imprinting, and metabolic disorders. Recent advances can help us understand the importance of epigenetic changes in both cancer development and tumor progression. In addition, epigenetic alterations may also be useful diagnostic and prognostic markers for the analysis of tumor progression.Split into two parts, the book opens with a comprehensive overview of the identification and analysis of epigenetic changes in cancer and the consequences of such changes during tumor development. The second part focusses on cancer specific epigenetic alterations and discusses the potential use of epigenetic markers as biomarkers in diagnosis, early cancer progression, and prognosis. Moreover, it reviews the therapeutic potential of epigenetic drugs. Given its scope, Cancer Epigenetics is an indispensable resource not only for researchers working in the field of human epigenetics and cancer research but also for advanced students seeking for an introduction into epigenetic mechanisms.

Der Blick zu den Sternen.- Ovids gewölbter Himmel.- Der Sonnenwagen.- Jupiter und Kallisto.- Jupiter und Europa.- Perseus und Andromeda.- Der Sternenhimmel im Jahreskreis.- Der Himmel im Frühling.- Sternzug: "Deichsellinie bis Spica".- Der Himmel im Sommer.- Sternzüge: "Fünfsternreihe" und "Großes Dreieck".- Der Himmel im Herbst.- Sternzug: "Kolurlinie".- Der Himmel im Winter.- Sternzüge: "Großer Wagen und Polarstern" und "Großes Sechseck um Orion".- Himmelskarten für das ganze Jahr.- Tabellen.- Karten.- Sternbilder und überliefertes Wissen.- Adler.- Andromeda.- Bärenhüter.- Becher.- Delphin.- Drache.- Fische.- Fuhrmann.- Großer Bär.- Großer Hund.- Hase.- Herkules.- Jungfrau.- Kassiopeia.- Kleiner Bär.- Kleiner Hund.- Krebs.- Leier.- Löwe.- Nördliche Krone.- Nördliche Wasserschlange.- Orion.- Pegasus.- Perseus.- Rabe.- Schlange, Schlangenträger.- Schütze.- Schwan.- Skorpion.- Steinbock.- Stier.- Waage.- Walfisch.- Wassermann.- Widder.- Zwillinge.- Wissenschaftliche Bilder.- Das Universum antiker Astronomen.- Beobachtung der Sonne.- Beobachtung der Sterne.- Die Bewegung der Sonne vor dem Fixsternhintergrund.- Die Deutung der Beobachtungen als Zwei-Kugel-Universum.- Die Bewegung von Planeten vor dem Fixsternhintergrund.- Kopernikanisches Universum.- Die Philosophie der Bilder.- Das naturwissenschaftliche Bild.- Zeiten "normaler Wissenschaft".- Selbst und Sein.- Quellen und weiterführende Literatur.- Quellenhinweise.- Schrifttum.- Frühe Quellen über Sternbilder und Mythen.- Menschen, Götter und Dämonen.- Namen und Kurzbeschreibungen.- Ähnliche oder nahezu äquivalente Gottheiten.- Symbole, Kennzeichen und Eigenschaften.- Funktion, Tätigkeit und Aufgabe.- Die Lage des Mondes und der Planeten auf der Ekliptik.- Himmelskarten und besondere Objekte.- Danksagung.- International gebräuchliche Fachbezeichnungen und Sternbildabkürzungen.- Verzeichnis der Sterne und Sternbilder.- Verzeichnis zur Mythologie.- Gesamtverzeichnis.

This textbook presents a range of classical philosophical approaches in order to show that they are unsuitable as a foundation for human rights. Only the conception of human dignity -based on the Kantian distinction between price and dignity - can provide a sufficient basis. The derivation of human rights from the principle of human dignity allows us to identify the most crucial characteristic of human rights, namely the protection of personhood. This in turn makes it possible (1) to distinguish between real moral human rights and spurious ones, (2) to assess the scope of protection for many codified human rights according to the criteria of "core" and "yard," and (3) offers a point of departure for creating new, unwritten human rights. This philosophical basis supports a substantial reassessment of the case law on human rights, which will ultimately allow us to improve it with regard to legal certainty, clarity and cogency.In the second edition, errors have been corrected in numerous places, the text has been made clearer and easier to understand. In addition, more recent human rights issues have been newly included, especially those related to the Corona epidemic and climate change. The textbook is primarily intended for advanced law students who are interested in a deeper understanding of human rights. It is also suitable for humanities students, and for anyone in the political or social arena whose work involves human rights and their enforcement.Each chapter is divided into four parts: Abstracts, Lecture, Recommended Reading, and Questions to check reader comprehension. Sample answers are included at the end of the book.

Einführung zur psychosomatischen Frauenheilkunde; Zur Arzt-Patient-Beziehung in der Frauenheilkunde; Aspekte der psychosomatischen Geburtshilfe; Symptome in der Schwangerschaft mit einer möglichen Psychogenese; Psychosomatische Aspekte der Geburt; Psychosomatische Aspekte des Wochenbetts; Psychosomatische Gynäkologie; Symptome und Krankheitsbilder in der Psychosomatischen Gynäkologie; Psychosomatische Aspekte kritischer Zeitabschnitte; Askekte der angwandten psychsomatischen Frauenheilkunde; Entwicklungen und Zukunftstendenzen in der psychosomatischen Geburtshilfe und Gynäkologie

This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 49th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2022). Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.

Historische Entwicklung des Begriffs 'Restless Legs Syndrom'. Chronologischer Abriß wichtiger Forschungsergebnisse.- Klinische Sympomatik des RLS. Definitionskriterien.- Sekundäre oder symptomatische Formen des RLS.- Familiäre Formen des RLS.- Diagnostik und Differentialdiagnose.- Spezielle neurophysiologische Diagnostik.- Zirkadiane Rhythmik des RLS.- Kernspintomographie und weitere bildgebende Untersuchungen bei RLS.- Pathophysiologie und Ätiologie des RLS.- Allgemeine Therapieprinzipien des idiopathischen und sekundären RLS.- Spezielle Therapie des idiopathischen und urämischen RLS. Praktische Therapieempfehlungen bei RLS. ' '