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This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer.It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression.The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeutic rationale.
Contents.- Preface.- List of Abbreviations.- List of Figures.- List of Tables.- Preface.- Chapter I: Introduction to Service Science.- Chapter II: Service Science And Sustainability.- Chapter III: Service sustainability paradigm as a basis for transformative service society.- Chapter IV: Inland Port in Malaysia: Logistical Revisit.- Chapter V: Think Global, Act Local: Strategies to Develop a Sustainable Mobility Program in Promoting Socioeconomic Development for a Better Quality Education,- Chapter VI: Media Psychology in New Era Communication.- Chapter VII: Critical Success Factors for Adopting Servitization Strategy.- Reference.- List of authors (author brief).- Index.
This book presents a theoretical study on aspect in Chinese, including both situation and viewpoint aspects. Unlike previous studies, which have largely classified linguistic units into different situation types, this study defines a set of ontological event types that are conceptually universal and on the basis of which different languages employ various linguistic devices to describe such events. To do so, it focuses on a particular component of events, namely the viewpoint aspect. It includes and discusses a wealth of examples to show how such ontological events are realized in Chinese. In addition, the study discusses how Chinese modal verbs and adverbs affect the distribution of viewpoint aspects associated with certain situation types.In turn, the book demonstrates how the proposed linguistic theory can be used in a computational context. Simply identifying events in terms of the verbs and their arguments is insufficient for real situations such as understanding the factivity and the logical/temporal relations between events. The proposed framework offers the possibility of analyzing events in Chinese text, yielding deep semantic information.
Sustainable development is the most important challenge facing humanity in the 21st century. The global economic growth in the recent past has indeed exhibited marked progress in many countries. Nevertheless, the issues of income disparity, poverty, gender gaps, and malnutrition are not uncommon in the global landscape, in spite of the upward growth of the economy and technological advances. This grim picture is further exacerbated by our growing human population, unmindful resource use, ever-increasing consumption trends, and changing climate. In order to protect humanity and preserve the planet, the United Nations issued the ¿2030 agenda for sustainable development,¿ which includes but is not limited to sustainable production and consumption practices, e.g. in a sustainable bioeconomy. The hallmark of the sustainable bioeconomy is a paradigm shift from a fossil-fuel-based economy to a biological-based one, which is driven by the virtues of sustainability, efficient utilization of resources, and ¿circular economy.¿ As the sustainable bioeconomy is based on the efficient utilization of biological resources and societal transformations, it holds the immense potential to achieve the UN¿s Sustainable Development Goals. This book shares valuable insights into the linkages between the sustainable bioeconomy and Sustainable Development Goals, making it an essential read for policymakers, researchers and students of environmental studies.
This open access book presents selected papers from International Symposium on Mathematics, Quantum Theory, and Cryptography (MQC), which was held on September 25-27, 2019 in Fukuoka, Japan.
Converting biomass to biofuels involves hydrolyzing cellulose to sugars using cost-intensive commercial enzymes - an expensive step that makes large-scale production economically non-viable.
This book discusses the building of comprehensive community support systems, which constitutes a key issue in social security reforms in Japan. The book comprises three parts: (I) Mapping Social Security in Japan, (II) Community-Based Integrated Care Systems in Japan, and (III) A Prospect of Community-Based Inclusive Society in Japan.
This book presents selected papers from the 4th Conference of the Transportation Research Group of India. It provides a comprehensive analysis of themes spanning the field of transportation encompassing economics, financial management, social equity, green technologies, operations research, big data analysis, econometrics and structural mechanics.
This book investigates in detail the deep learning (DL) techniques in electromagnetic (EM) near-field scattering problems, assessing its potential to replace traditional numerical solvers in real-time forecast scenarios.
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