Bøker utgitt av Springer Verlag, Singapore

This atlas presents dermoscopic-histopathological correlations of dermatologic and pathological presentations seen in the Asian subcontinent. The disorders have been explained with the help of state of the art clinical, dermoscopic and pathological figures of various entities in skin of color. The format has been kept simple and easy to understand which is deciphered through dermoscopic and histopathological correlation. This title also emphasizes on atypical presentations and rare dermoscopic features with the help of thorough description covering clinical and pathological manifestations, diagnosis, and differential diagnosis.Written for dermatologists, dermato-pathologists, dermoscopists and residents of dermatology, this atlas is a detailed visual guide to effectively evaluate and diagnose various skin disorders.

The book covers advances in critical care pediatric nephrology, including care of sick children with acute kidney injury. The book contains detailed guidance on point of care ultrasound in children with acute kidney injury and use of biomarkers in critically sick children.This is an annual theme-based book with the current theme of 'point of care ultrasound in critical care pediatric nephrology and newer diagnostics in acute kidney injury'. This is the first book of the set of books to be published annually with a different theme related to critical care pediatric nephrology each year with the collaboration of the Pediatric Continous Renal Replacement Therapy (PCRRT) Foundation and International Collaboration of Nephrologists & Intensivists for Critical Care in Children (ICONIC). This annual updates book contains 20 chapters, written and edited by leading experts in pediatric intensive care, pediatric nephrology and nephrologists specializing in point of care ultrasound from across the globe. It includes top studies in the last few years in critical care pediatric nephrology on point of care ultrasound and diagnostics. Chapters cover scientifically updated information by international experts on each topic. It offers assistance to pediatricians, pediatric nephrologists, pediatric intensivists and residents.

The main focus of this book is providing evidence on and interpreting the risks associated with heated tobacco products (HTPs) in terms of their health effects and social effects; in addition, the author introduces a harm reduction theory related to HTPs and electronic cigarettes. The book also addresses the history of these products, their marketing strategies, and policy implications. These products are new and the accompanying health risks have yet to be determined. However, since Japan accounts for more than 80% of the world¿s market for IQOS, the most popular heated tobacco product, researchers around the globe will be very interested in the outcomes. Written by a leading researcher in the field of tobacco control, Science and Practice for Heated Tobacco Products offers a valuable, unique resource for researchers in the fields of epidemiology, public health, social sciences, addiction, and tobacco research. Since tobacco is associated with a host of diseases including cancers, cardiovascular diseases, diabetes mellitus, and respiratory illnesses, researchers and healthcare workers whose work involves these diseases will find this book both thought provoking and insightful.

This surgical manual provides a step-by-step guide to various surgical procedures for patients with thyroid eye disease (TED). The key surgical steps are covered in detail, with intra-operative photographs. The manual addresses all aspects of TED, including the basic anatomy, surgical preparation, evaluation of imaging, and surgical procedures. TED is commonly encountered by oculoplastic surgeons and general ophthalmologists in their daily practice, and restoration of the normal appearance is vital to patients and their families. Surgical treatments for TED include basic oculoplastic surgery, complex eyelid surgery, strabismus surgery, orbital surgery, and aesthetic procedures.All of the contributing authors are eminent experts with vast experience in treating TED. High-resolution images will help readers understand the key surgical steps, and are combined with a minimal amount of text, reflecting the book's focus on surgical technique. Offering a complete guide that contains all relevant surgical knowledge on TED, presented in a highly practice-oriented format, the book is a must-read for every surgeon whose work involves managing TED.

This surgical manual provides a step-by-step guide to various surgical procedures for patients with thyroid eye disease (TED). The key surgical steps are covered in detail, with intra-operative photographs. The manual addresses all aspects of TED, including the basic anatomy, surgical preparation, evaluation of imaging, and surgical procedures. TED is commonly encountered by oculoplastic surgeons and general ophthalmologists in their daily practice, and restoration of the normal appearance is vital to patients and their families. Surgical treatments for TED include basic oculoplastic surgery, complex eyelid surgery, strabismus surgery, orbital surgery, and aesthetic procedures.All of the contributing authors are eminent experts with vast experience in treating TED. High-resolution images will help readers understand the key surgical steps, and are combined with a minimal amount of text, reflecting the book's focus on surgical technique. Offering a complete guide that contains all relevant surgical knowledge on TED, presented in a highly practice-oriented format, the book is a must-read for every surgeon whose work involves managing TED.

The book covers all aspects of endoscopic biopsies of the stomach inclusive of gastritis and gastropathies. It highlights the best way of handling of endoscopic biopsies in the endoscopic room by the gastroenterologist. It elucidates various steps involved in processing of the biopsy, tissue embedding and paraffin sectioning, approach to interpretation, various precautions that require to be taken while interpreting the biopsies, and the essential background knowledge of the interpreter. The book highlights the importance of the little things for a proper reading like matching of the tissue fragments received and the number of tissue present on a slide after the paraffin section.Chapters cover various forms of gastritis, and the easiest approach for daily routine by avoiding the cumbersome classifications and staging formulated for gastritis. It also discusses the utilization of the right nomenclature for acute and chronic gastritis and various other subtypes of gastritis. Chapters include various rarer and infrequently come across conditions of both acute and chronic gastritis, special form of gastritis and infective conditions. It also includes unusual forms of non-neoplastic gastric pathologies such as, a condition, where the gastric mucosa is affected not only by direct exposure to various irritants but may also be affected by many systemic diseases. It also highlights the frequently observed changes in chronic renal and liver failures. The book is targeted to all the practicing pathologists as well as graduate and post graduate students who are keen to learn about non-neoplastic gastric pathology at various levels.

This edited book describes what fragile bone is, how the condition is assessed, and how it can be treated. It is intended for multi-professional trainees and practitioners in health and social care fields who care for and treat the elderly.Chapters within the book provide the latest advances in cell and molecular biology, morphology, radiology, and the biomechanics of bone in health and disease. The basic concept of ¿Remodeling¿ and ¿Modeling¿ is described for better understanding of the mechanisms of osteoporosis. Methods of identifying and assessing osteoporosis are described, as are risk factors for bone fracture and non-unions. Furthermore, the effects of various drugs used to treat osteoporosis at both material and structural levels of bone and their cost effectiveness are described. Operative treatments for fracture that maintain or improve the quality of life of patients are includedTreatment of Osteoporotic Fracture and Systemic Skeletal Disorders attempts to provide a holistic and translational view of the pathogenesis and treatment of osteoporosis and some other musculoskeletal diseases, with an overview of treatment modalities in various clinical settings.

This book is aimed at illustrating the common complicated ocular trauma with typical signs, examinations, surgical procedures and conservative management to clinical practitioners including the nurses, medical students, residents, fellows and ophthalmologists, and help them make the most appropriate decision on the diagnosis and management of such patients. There are 23 chapters introduced in the book, which covers all types of complicated ocular trauma with brief case reports combined with the most comprehensive pictures. For each disease, a brief introduction, explanation as well as management are offered to the readers. With the illustrative figures and explanations, the goal of making the right diagnose, offering the best advice or treatment to the patients, and understanding surgical procedures would be easily achieved. This book is useful for readers to be fully prepared for the challenge of complicated ocular traumatic cases.This is the fifth volume of the book series Ocular Trauma.

This book presents essential information on the various concepts of biomechanics and kinesiology applied to human body, also describing in depth the understanding of the various physical and mathematical principles applied towards understanding of this science of movement. It tries to simplify this biological movement science by facilitating easy understanding of the various applications of the forces acting on the human body. This book provides a deep insight to the clinical gait analysis and it¿s interpretations with graphical outputs, it also covers important topics such as biomechanics of important human joints such as neck, shoulder, spine, hip, knee and ankle with their recent advances. It also includes chapters on biomechanical instrumentation and their interpretation. Another highlight of the book is chapters on biomechanical motion analysis systems used for athletes. This book offers a valuable resource for medical and paramedical students, researchers and clinicians practicing musculoskeletal and manual therapy, aiding researchers gaining insight to human biomechanics.

Ankylosing Spondylitis is a chronic autoimmune disease that affects about 1-3% of the world population. This debilitating disease affecting primarily young males exerts considerable socio-economic consequences. The exact pathogenesis of AS has not yet been fully understood; therefore, novel, detailed information sources are required. This book offers cutting-edge knowledge about the molecular basic and immunological mechanisms involved in the pathogenesis of Ankylosing Spondylitis. It is one of the scarce scientific resources discussing the environmental factors triggering the disease, along with the clinical manifestations, diagnostic methods, and treatments. This book covers the most recent and reliable researches and developments about spondyloarthropathies in order to provide elaborated, integrated guidance on the molecular mechanisms of Spondyloarthropathies. It will prove helpful for rheumatologists, immunologists, biologists, geneticists, and medical science students who wish to learn more about SpAs.

This book aims to highlight all the existing information available on first and mid-trimester imaging of palate in prenatal ultrasound and to develop a methodical approach in imaging the palate. As formation of the palate is completed by 11 weeks of gestation and as there are no evolving changes in palatine anatomy at the mid-trimester, diagnosis of palatine clefts can now completely be shifted to late first-trimester. First-trimester evaluation of palate is now gaining importance and a number of techniques have currently been proposed by different authors.This book covers the existing literature and recent 2D and 3D techniques in evaluating palate and helps in the early detection of palatine clefts in the first trimester. Orofacial clefting is one of the most common birth defects and the burden of it in developing countries is substantial. This book helps in improving the counseling options for the obstetrician and the couple early in gestation. It includes 2D and 3D images of various types of palatine clefts and the nuances in imaging the secondary palate extensively. 3D images of the palate also help the multi-disciplinary team especially the maxillofacial surgeons involved in managing orofacial clefts. It also includes videos for easy understanding.This book is a ready reckoner for the imaging specialists and students /trainees involved in prenatal diagnosis. It provides essential information in diagnosing orofacial cleft both to the novice and to the skilled professionals involved in the field of diagnostic fetal ultrasound.

This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.

This book provides practical information on applications of multi-modal EEG monitoring in patients with severely neurologically diseases. The First part systematically introduces the modern EEG techniques, and multi-modal EEG monitoring system for severe neurological illness. In the second part, identification of EEG artifacts and interpretation of common abnormal EEG patterns is presented. Accompanying more than 50 typical cases and 200 EEG records, the following chapters discusses EEG¿s changes and clinical significance in coma, ischemic-hypoxic encephalopathy, status epilepsy, Creutzfeldt-Jakob disease, traumatic brain injury, and other diseases in details. In addition, application of multi-modal EEG in monitoring intracranial pressure and predicting suicide risk is also included. It will be a valuable reference for professionals in neurology, neurosurgery, emergency care, psychiatry, technology specialists of EEG and senior nurses with basic EEG monitoring knowledge.

This volume thoroughly describes the fundamentals of a new multidisciplinary field of study that aims to deepen our understanding of the human body by combining medical image processing, mathematical analysis, and artificial intelligence. Multidisciplinary Computational Anatomy (MCA) offers an advanced diagnosis and therapeutic navigation system to help detect or predict human health problems from the micro-level to macro-level using a four-dimensional, dynamic approach to human anatomy: space, time, function, and pathology. Applying this dynamic and ¿living¿ approach in the clinical setting will promote better planning for ¿ and more accurate, effective, and safe implementation of ¿ medical management. Multidisciplinary Computational Anatomy will appeal not only to clinicians but also to a wide readership in various scientific fields such as basic science, engineering, image processing, and biomedical engineering. All chapters were written by respected specialists and feature abundant color illustrations. Moreover, the findings presented here share new insights into unresolved issues in the diagnosis and treatment of disease, and into the healthy human body.

This book presents the latest knowledge on all aspects of osteoarthritis of the knee. Beyond offering a thorough evidence-based review of the available treatment options, it provides helpful information on such fundamental aspects as anatomy, biomechanics, biochemistry, etiology, pathogenesis, and radiologic assessment. The treatment-oriented chapters cover non-pharmacologic treatment, drug treatment, intra-articular drug and/or cell-based injection therapy, arthroscopic treatment, osteotomy, and joint replacement surgery. The goal is to equip the reader with a sound understanding of both the condition itself and the appropriate treatment strategy in different situations. The importance of taking into account factors such as the degree of arthritis, patient activity, lifestyle, and pain when formulating that strategy is emphasized. The fact that the book extends well beyond the description of surgical treatments means that it will be an excellent source of information and guidance forgeneral clinicians as well as for those who specialize in the management of musculoskeletal disorders.

The upcoming trends in healthcare are intended towards improving the overall quality of life. In the past,management of health issues were limited to clinics and hospitals and managing patient¿s data and analyzing it. This procedure was difficult and time consuming. A great effort was also needed in diagnosing the cause and type of disease, but this all has changed now. As advancement in research and technologies, a positive impact on healthcare is seen. This book assesses the need and era of smart healthcare and delivers content relevant to current age and time. It describes the trend, usage and practicality of IWMDs i.e. Wearable Medical Device or Sensors (WMSs) and Implantable Medical Devices (IMDs) and how they enhance the awareness of daily healthcare.It establishes a relation and conjunction of daily healthcare monitoring with clinical healthcare. A healthcare system is called smart when there is an ability to make decisions, which comes from data analytics. Smart healthcare systems possess capability of data analytics and IoT based services which can be implemented on smart phones using cloud technology. This book discusses various research trends and technologies related to innovations and advancements for smart healthcare systems. It also elaborates challenges, scope upcoming techniques, devices and future directions for smart healthcare systems.The proposed book would in particular benefit researchers interested in interdisciplinary sciences, It would also be of value to faculty, research communities, and researchers from diverse disciplines who aspire to create new and innovative research initiatives.

The book covers all aspects of eye health in South-East Asia from public health to health system to education to industry in 6 sections. The World Health Organization (WHO) South-East Asia region comprises of 11 countries - Bangladesh, Bhutan, DPR Korea, India, Indonesia, Maldives, Myanmar, Nepal, Sri Lanka, Thailand and Timor-Leste. This region is home to 26% of world population; there is a disproportionate amount of blindness (30.6%) and visual impairment (36%).This is a first of its kind book that discusses common conditions of visual impairment and blindness in the South-East Asia region. In addition, the book documents the current eye care industry in the region and the contribution of all eye health INGOs in eye care program planning and service delivery for many decades. Majority of the countries in the South-East Asia region are categorized in ¿middle-income country¿ group. This book discusses the common challenges in these countries such as, suboptimal public expenditure in health, acute shortage of skilled eye health workforce, and rudimentary health industry. The book covers the following 6 sections:1. Geographic description and health indices of the region2. Health system evolved over years, including universal eye health, health financing and health management information system (HMIS)3. Common eye problems including non-communicable disease NCD (and diabetic retinopathy), neglected tropical disease NTD (and Trachoma)4. Health workforce in the region that includes ophthalmologists, optometrists, and allied ophthalmic personnel5. Eye health support in the region of 13 international non-government organizations (INGOs) working for decades6. Eye health industry in the region that includes spectacles, ophthalmic devices and equipment and the pharma industry The book would be a useful resource for ophthalmologists, all public health personnel and policy makers in eye health in the South-East Asia region specifically and all ophthalmologists and scientists interested in public health all over the world as well as for program planning to reach the 'Health for All' strategy by 2030 (United Nations Sustainable Development Goal, SDG 2030).

This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, novel biomarkers, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments for possible functional cure of HBV infection.In this second edition, authors provides recent updates in epidemiology, biomarkers, antivirus therapy, and novel therapy for functional cure of chronic hepatitis B virus infection.The book is a valuable resource for medical students, physicians, and researchers who are interested in management of patients with chronic HBV infection and investigation HBV infection.

This book provides step-by-step illustrated descriptions of diverse vocal fold injection techniques, including some not previously described. The aim is to provide laryngologists in general, and especially those who are less experienced, with the detailed understanding and guidance needed in order to achieve optimal outcomes. Highly experienced experts describe approaches via the transoral, transnasal, and transcutaneous routes and offer guidance on indications, injection materials, pre- and postoperative care, and the management of complications. Special considerations that must be borne in mind when employing different vocal fold injection techniques, in different settings, are also carefully explained. In offering comprehensive, up-to-date information on this minimally invasive and cost-effective procedure, Vocal Fold Injection will be an essential aid for practitioners.

This book is designed to provide a crisp and necessary information for all the under-graduate and post-graduate medical students, Oral and Maxillofacial Surgeons, ENT Surgeons, General Surgeons, General Dentists and other health care workers who deal with TMDs in their practise. It includes contributions from eminent surgeons across the world who treat TMJ disorders and diseases using various conventional to modern state of the art techniques.Temporomandibular joint disorders (TMDs) are familiar yet difficult to diagnose in routine practice due to the complexity of the joint and its surrounding structures. The symptoms usually associated with TMDs present with pain, joint sounds such as click or crepitus, difficulty during mastication, reduced mouth opening are some of the many presentations. Definite diagnosis of the TMDs can be challenging as the patients present with varying symptoms. These disorders of the joint can vary from a simple disc displacement to complex pathologies. Management of the TMDs can be tricky and hence need a thorough evaluation of the joint and surrounding structures. There has been a tremendous leap in managing these disorders from simple conservative management to several advanced surgeries to salvage the joint. This compilation highlights all the relevant details regarding TMDs and its management which will offer utmost details to practising surgeons who often deal with TMDs. This book will be a delight to read for all the clinicians and surgeons who are interested in treating the small yet complex jaw joint in the facial region.