Bøker utgitt av Springer-Verlag New York Inc.

Providing a true integration of pathology with clinical management, this volume presents a practical, comprehensive text on benign and malignant disease of the adult bladder.

The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified.

This book provides a concise, state-of-the art review of the surgical treatment of metabolic syndrome and diabetes mellitus.

Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials.

This book is devoted to grain legumes and include eight chapters devoted to the breeding of specific grain legume crops and five general chapters dealing with important topics which are common to most of the species in focus.

This book is unique in covering a wide range of design and analysis issues in genetic studies of rare variants, taking advantage of collaboration of the editors with many experts in the field through large-scale international consortia including the UK10K Project, GO-T2D and T2D-GENES. Chapters provide details of state-of-the-art methodology for rare variant detection and calling, imputation and analysis in samples of unrelated individuals and families. The book also covers analytical issues associated with the study of rare variants, such as the impact of fine-scale population structure, and with combining information on rare variants across studies in a meta-analysis framework.Genetic association studies have in the last few years substantially enhanced our understanding of factors underlying traits of high medical importance, such as body mass index, lipid levels, blood pressure and many others. There is growing empirical evidence that low-frequency and rare variants play animportant role in complex human phenotypes. This book covers multiple aspects of study design, analysis and interpretation for complex trait studies focusing on rare sequence variation. In many areas of genomic research, including complex trait association studies, technology is in danger of outstripping our capacity to analyse and interpret the vast amounts of data generated. The field of statistical genetics in the whole-genome sequencing era is still in its infancy, but powerful methods to analyse the aggregation of low-frequency and rare variants are now starting to emerge.The chapter Functional Annotation of Rare Genetic Variants is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This volume focuses on the whisker system, which is an exquisite model to experimentally approach sensorimotor integration in the mammalian brain.In this book, authors examine the whisker system on many different levels, ranging from the building blocks and neuronal circuits to sensorimotor behavior.

Reoperative Hand Surgery is a major contribution to the literature, offering a wide range of reoperative options for challenging problems that face the reconstructive hand surgeon after failed primary surgery.

Optical Interconnects in Future Data Center Networks covers optical networks and how they can be used to provide high bandwidth, energy efficient interconnects for future data centers with increased communication bandwidth requirements.

Management of the Patient at High Risk for Breast Cancer provides a state-of-the art review of patients who are at high risk for breast cancer, how to identify them, the tools available for risk assessment and quantification and indications for genetic counseling and testing.

Policing in Central and Eastern Europe has changed greatly since the fall of the Berlin Wall. Some Central and Eastern European countries are constituent members of the European Union, while others have been trying to harmonize with the EU and international requirements for a more democratic policing and developments in accordance with Western European and international policing standards, especially in regard to issues of legality and legitimacy.  Changes in the police training system (basic and advanced), internationalization of policing due to transnationalization of crime and deviance, new police organizational structures and agencies have impacted new cultures of policing (from exclusively state to plural policing).    This timely volume examines developments in the last two decade to learn the nature of these changes within Central and Eastern Europe, and their impact on police culture, as well as on society as a whole. The development of police research has varied widely throughout Central and Eastern Europe: in some countries, it has developed significantly, while in others it is still in its infancy. This work will allow for a transfer of ideas and models of police organization and policing is also need to be studies closely, with an aim to provide consistent and comparable data across all of the countries discussed. For the twenty countries covered, this systematic work provides: short country-based information on police organization and social control, crime and disorder trends in the last 20 years with an on policing, police training and police educational systems, changes in policing in the last 20 years, police and the media, present trends in policing (public and private, multilateral, plural policing), policing urban and rural communities, recent research trends in research on policing ¿ specificities of research on police and policing (researchers and the police, inclusion of police researchers in policymaking and police practice) and future developments in policing.

This book describes computing innovation, using non-volatile memory for a sustainable world. It appeals to both computing engineers and device engineers by describing a new means of lower power computing innovation, without sacrificing performance over conventional low-voltage operation.

Textbook of Laser Refractive Cataract Surgery is a comprehensive reference for the general ophthalmologist and cataract surgeon regarding the explosive new technology in femtosecond laser cataract surgery.

This book offers thorough coverage of emergencies in dermatology, from the basics of critical care for dermatologic emergencies, to neonatal and pediatric emergencies, infectious emergencies, drug eruptions and HIV-AIDS-related emergencies, among many others.

The Handbook of Crisis Intervention and Developmental Disabilities synthesizes a substantive range of evidence-based research on clinical treatments as well as organizational processes and policy. This comprehensive resource examines the concept of behavioral crisis in children and adults with special needs and provides a data-rich trove of research-into-practice findings. Emphasizing continuum-of-care options and evidence-based best practices, the volume examines crisis interventions across diverse treatment settings, including public and private schools, nonacademic residential settings as well as outpatient and home-based programs. Key coverage includes:Assessment of problem behaviors.Co-occurring psychiatric disorders in individuals with intellectual disabilities.Family members¿ involvement in prevention and intervention.Intensive treatment in pediatric feeding disorders.Therapeutic restraint and protective holding.Effective evaluation of psychotropic drug effects.The Handbook of Crisis Intervention and Developmental Disabilities is a must-have resource for researchers, scientist-practitioners, and graduate students in clinical child, school, developmental, and counseling psychology, clinical social work, behavior therapy/analysis, and special education as well as other related professionals working across a continuum of service deliverysettings.

Color Atlas of Fetal and Neonatal Histology serves as a comprehensive atlas of the developmental histology of the major organs from 15 weeks gestation to the neonatal period. In addition, there are many color photomicrographs at key developmental stages to assist the reader in identifying appropriate histologic changes at each developmental stage.

Interstitial lung diseases comprise a significant part of any respiratory medicine practice. Organized in an easy to follow format, each disease specific chapter includes tables outlining diagnostic approach, differential diagnosis, disease monitoring, and treatment.

Diagnostic Pathology of Ovarian Tumors offers a focus on the pathology of ovarian neoplasia with detailed clinically relevant information for practicing pathologists not found in other more general volumes of gynecologic pathology.

Mechanical Self-Assembly: Science and Applications introduces a novel category of self-assembly driven by mechanical forces.

Addressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature.

This unique book provides a retrospective analysis of the changes in survival outcomes at the University of Texas, M.D. Anderson Cancer Center is the only book to concurrently present longitudinal data on survival outcomes across the spectrum of rare and common cancers.

Coverage is given to progress in a variety of clinical settings, including programs of organ and function preservation, curative treatments, unresectable disease, adjuvant treatments in high-risk patients, and recurrent/metastatic disease.

It covers the spectrum of redo cardiac operations, including coronary artery bypass, mitral valve repair, reoperation for prosthetic mitral valve endocarditis, aortic arch reoperation, descending and thoracoabdominal aortic reoperation, and reoperations following endovascular aortic repair.

this book presents the latest advances in graphene nanoelectronics and the potential benefits of using graphene in a wide variety of electronic applications. The book also provides details on various methods to grow graphene, including epitaxial, CVD, and chemical methods.

Self-expandable stents were initially placed for the treatment of cardiovascular diseases but now play an integral role in the relief of benign and malignant obstruction of the gastrointestinal tract and biliary system.