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In turn, this will lead to new therapeutic strategies as well as drug development projects by the pharmaceutical industry.This book presents a series of reviews describing studies that have resulted in identification of new potential drug targets for age-related disorders.

This book blends the science of biology, medicine, bioinorganic chemistry, bioorganic chemistry, material and physical sciences, biomedical engineering, electrical, mechanical, and chemical science to present a comprehensive range of advancements.

This book gives insights in the vivid research area of early mathematics learning. The research foci of the chapters comprise children's mathematical reasoning, early years mathematics teaching, and the role of parents for children's mathematical development.

Set in both the socio-economic and ideas contexts, these controversies show the eminently conventional and political nature of the CPI and, therefore, of many other macroeconomic indicators, such as growth or productivity.

This book constitutes selected and revised papers from the Second International Conference on Research and Education in Urban History in the Age of Digital Libraries, UHDL 2019, held in Dresden, Germany, in October 2021. The 11 full papers presented in this volume were thoroughly reviewed and selected from 41 submissions.

Sufficient dimension reduction through independence and conditional mean independence measures - Yuexiao Dong.- Model-based inverse regression and its applications - Tao Wang and Lixing Zhu.- Cook''s Fisher Lectureship revisited for semi-supervised data reduction - Jae Keun Yoo.- Global testing under sparse alternatives for single index models - Qian Lin, Zhigen Zhao, and Jin Liu.- Supervised dimension reduction for spatian data - Christoph Muehlmann, Hanna Oja, and Klaus Nordhausen.- Sufficient dimension folding with categorical predictors - Yuanwen Wang, Yuan Xue, Qingcong Yuan, and Xiangrong Yin.

This volume explores options for a sustainable maritime domain, including maritime transportation, such as, Maritime Spatial Planning (MSP), maritime education and training, maritime traffic and advisory systems, maritime security.

This book brings together the expertise of two authors involved in initiating the development of Online Family Dispute Resolution (OFDR), while also examining the unique Australian system.

This volume presents lectures given at the Wisla 19 Summer School: Differential Geometry, Differential Equations, and Mathematical Physics, which took place from August 19 - 29th, 2019 in Wisla, Poland, and was organized by the Baltic Institute of Mathematics.

This book, for the first time, has gathered native descriptions of Hot and Cold theory in different traditional medicines, including traditional Chinese medicine, Persian (Humoral, Unani) medicine, Ayurvedic medicine and Latin American and Caribbean medicines.

 This book summarizes the latest research on advanced intelligent systems in the fields of energy and electrical engineering, presented at the second edition of the International Conference on Advanced Intelligent Systems for Sustainable Development (AI2SDΓÇÖ2019), held in Marrakech from 8 to 11 July 2019, Morocco. This book is intended for researchers, professionals and anyone interested in the development of advanced intelligent systems in the electrical engineering sector. The solutions featured focus on three main areas: motion control in complex electromechanical systems, including sensorless control; fault diagnosis and fault-tolerant control of electric drives; and new control algorithms for power electronics converters. In addition, the book includes a range of research using new technologies and advanced approaches. Offering a platform for researchers in the field of energy to share their work related to the problem of management and optimization of energy, which is a major current concern, the book mainly focuses on areas that go hand in hand with the Industrial Revolution 4.0, such as solar energy computing systems, smart grids, hydroelectric power computing systems, thermal and recycling computing systems, eco-design intelligent computing systems, renewable energy for IT equipment, modeling green technology, and renewable energy systems in smart cities. The authors of each chapter report the state of the art in the topics addressed and the results of their own research, laboratory experiments, and successful applications in order to share the concept of advanced intelligent systems and appropriate tools and techniques for modeling, storage management, as well as decision support in the field of electrical engineering. Further, the book discusses a number of future trends and the potential for linking control theory, power electronics, artificial neural networks, embedded controllers and signal processing.

This book investigates why and how cycle and walking paths can help to promote the regeneration of marginalized areas facing depopulation and economic decline.

This book covers the International Conference on Engineering Research and Applications (ICERA 2021), which took place at Thai Nguyen University of Technology, Thai Nguyen, Vietnam on December 1-2, 2021, and provided an international forum to disseminate information on latest theories and practices in engineering research and applications.

This Open Access book presents an international group of scholars seeking to understand how youth from different cultures relate to modern multidimensional concepts of citizenship, and the roles that education and society have in shaping the views of the world's future citizens.

This edited volume provides managers, as well as students, with the best practices in effectively leading the 21st century workforce and managing change. It applies positive principles arising from the newly emerging fields of positive psychology, positive change, and positive organizational studies to the field of leadership and change;

This book focuses on quinoa, providing background information on its history, summarizing recent genetic and genomic advances, and offering directions for future research.

A follow-up to Emerging Issues and Controversies in Infectious Diseases, this volume provides a comprehensive review of topical issues in infectious diseases, highlighting the controversies related to the newest findings and recommendations.

The two-volume set IFIP AICT 591 and 592 constitutes the refereed proceedings of the International IFIP WG 5.7 Conference on Advances in Production Management Systems, APMS 2020, held in Novi Sad, Serbia, in August/September 2020.The 164 papers presented were carefully reviewed and selected from 199 submissions.

This book provides insights into smart ways of computer log data analysis, with the goal of spotting adversarial actions.

This book presents the latest advances in computational intelligence and data analytics for sustainable future smart cities. It focuses on computational intelligence and data analytics to bring together the smart city and sustainable city endeavors.

This book presents experimental and numerical findings on reducing shock-induced separation by applying transition upstream the shock wave.

This open access book focuses on processing, modeling, and visualization of anisotropy information, which are often addressed by employing sophisticated mathematical constructs such as tensors and other higher-order descriptors. It also discusses adaptations of such constructs to problems encountered in seemingly dissimilar areas of medical imaging, physical sciences, and engineering. Featuring original research contributions as well as insightful reviews for scientists interested in handling anisotropy information, it covers topics such as pertinent geometric and algebraic properties of tensors and tensor fields, challenges faced in processing and visualizing different types of data, statistical techniques for data processing, and specific applications like mapping white-matter fiber tracts in the brain.The book helps readers grasp the current challenges in the field and provides information on the techniques devised to address them. Further, it facilitates the transfer of knowledge between different disciplines in order to advance the research frontiers in these areas.This multidisciplinary book presents, in part, the outcomes of the seventh in a series of Dagstuhl seminars devoted to visualization and processing of tensor fields and higher-order descriptors, which was held in Dagstuhl, Germany, on October 28¿November 2, 2018.

Changes in atmospheric carbon dioxide concentrations and global climate conditions have altered photosynthesis and plant respiration across both geologic and contemporary time scales.

This book presents the facet theoretical framework as a tool for facilitating the conception of complex animal behaviour research and the design of research procedures through employing mapping sentences.

The five-volume set IFIP AICT 630, 631, 632, 633, and 634 constitutes the refereed proceedings of the International IFIP WG 5.7 Conference on Advances in Production Management Systems, APMS 2021, held in Nantes, France, in September 2021.*The 378 papers presented were carefully reviewed and selected from 529 submissions.

This book, planned by the International Society for Frontotemporal Dementias, is distinctive as it opens a window to a wide landscape about the biology of FTD. Thus, the book represents a moment of reflection on the present state of our knowledge of FTD and a collective vision toward scientific progress.

This book presents a comprehensive collection of case studies on augmented reality and virtual realty (AR/VR) applications in various industries. Augmented reality and virtual reality are changing the business landscape, providing opportunities for businesses to offer unique services and experiences to their customers.

Since proteoglycans modulate cell adhesion and migration they are important organizers of the extracellular matrix within the proper stem cell niche.

This book provides a collection of contributed chapters, delivering a comprehensive overview of topics related to the synthesis and crystal growth of nitride compounds under supercritical ammonia conditions.

This book examines the global movement of putting more emphasis on students' social and emotional development in education. a discussion in which attention is given to political and ethical questions about the desirability of treating social and emotional attributes as educational goals.