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Each volume brings together some of the most pre-eminent scientists working on cancer biology, cancer treatment, cancer diagnosis, cancer prevention and regenerative medicine to share information on currently ongoing work which will help shape future therapies.

This book provides an in-depth description and discussion of different multi-modal diagnostic techniques for cancer detection and treatment using exact optical methods, their comparison, and combination.

This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ¿vectors¿ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis.This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.

This proceedings volume gathers together selected works from the 2018 ¿Asymptotic, Algebraic and Geometric Aspects of Integrable Systems¿ workshop that was held at TSIMF Yau Mathematical Sciences Center in Sanya, China, honoring Nalini Joshi on her 60th birthday. The papers cover recent advances in asymptotic, algebraic and geometric methods in the study of discrete integrable systems.The workshop brought together experts from fields such as asymptotic analysis, representation theory and geometry, creating a platform to exchange current methods, results and novel ideas.This volume's articles reflect these exchanges and can be of special interest to a diverse group of researchers and graduate students interested in learning about current results, new approaches and trends in mathematical physics, in particular those relevant to discrete integrable systems.

This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling.This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained.By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.

Reflecting the diverse and profound changes triggered by the latest wave of economic globalization, this book highlights various governance responses at national, regional and global levels. The topics covered are wide-ranging and include economic history and development, European integration, exchange rate arrangements, industrial and labor economics, international cooperation and multilateralism, and public choice.The book is divided into three parts: The first part, which contains contributions by Barry Eichengreen and Marc Flandreau, is devoted to economic history. The second part examines open economy macroeconomics with a focus on Europe, including contributions by Jurgen von Hagen and Paul Krugman. The third part presents contributions to international political economy, and related interdisciplinary topics. This Festschrift is written in honor of Jorge Braga de Macedo, Professor Emeritus of Economics at the Nova School of Business and Economics and a distinguished Portuguese academic whose work has an impressive global reach. The contributions, written by a selection of international authors, deal with his oeuvre covering the wide range of topics broached in this book, as his publication record amply attests.

The contributing authors, which include distinguished academics, public officials from important national authorities, and market operators, discuss and demonstrate how this technology can be a driver of innovation and yield positive effects in our societies, legal systems and economic/financial system.

This book shares new research findings and practical lessons learned that will foster advances in digital design, communication design, web, multimedia and motion design, graphic design and branding, and other related areas.

Plant growth and development is closely dependent on the plant environment, including the wide-spread presence of organic and inorganic xenobiotics and pollutants. Currently, heavy metals are the most common inorganic environmental pollutants and they have pronounced effects and consequences not only for plants, but also for the ecosystem in which the plants form an integral component. It has been suggested that these contaminants accumulate in agricultural crops, thus entering the food chain and posing a significant health risk. Plants growing in polluted sites exhibit altered metabolism, reduced growth, and decreased biomass production. These pollutants adhere to plant roots and exert physical or chemical toxicity and subsequently cell death in plants. Yet, plants have developed various defence mechanisms to counteract the toxicity induced by heavy metals. Only detailed study of the processes and mechanisms would allow researchers and students to understand the interactions, responses, and adaptations of plants to these pollutants; however, there are several unresolved issues and challenges regarding the interaction and biological e¿ects of heavy metals. Therefore, this volume provides relevant, state-of-the-art findings on environmental phytotoxicity and the mechanisms of such interactions at the cellular and molecular levels. This volume consists of chapters on relevant topics contributed by different experts or group of experts so as to make available a comprehensive treatise designed to provide an in-depth analysis of heavy metals phytotoxicity.This book may serve as a reference to scientists, researchers and students in the fields of toxicology, environmental toxicology, phytotoxicology, plant biology, plant physiology, plant biochemistry and plant molecular biology, and especially those interested in heavy metals toxicology.

This book presents the proceedings of the 4th International Symposium on Materials and Sustainable Development ISMSD2019 (CIMDD2019), will include a 3-day Conference (12 - 14 November).

This book presents the proceedings of the 4th International Symposium on Materials and Sustainable Development ISMSD2019 (CIMDD2019), will include a 3-day Conference (12 - 14 November).

This edited volume seeks to integrate research and scholarship on the topic of embodiment, with the idea being that thinking and feeling are often grounded in more concrete representations related to perception and action.

In the second section, "Adjusting to Place Attachment Disruption During and After a Pandemic," we focus on adaptive processes and responses that could enable people to adjust positively to place attachment disruption.

This book provides an overview of the aviation sector by focusing on all major aspects embedded in the environment (subsystems) and the market of aviation.

This handbook on Artificial Intelligence (AI) in healthcare consists of two volumes. The first volume is dedicated to advances and applications of AI methodologies in specific healthcare problems, while the second volume is concerned with general practicality issues and challenges and future prospects in the healthcare context.

This book highlights the vital necessity for combining sustainable development processes from different areas, with applications in areas such as science, education and production sectors. This book fills in the gap in respect of publications addressing aspects of innovation and sustainable development and focuses on a range of areas, such as I.

This book describes the alarming condition of agriculture in the Anthropocene, when the ethical conception of agriculture as a service of common utility for both society and environment has progressively been marginalized.

This proceedings book presents contributions to the International Conference on Critical Thinking in the Sustainable Rehabilitation and Risk Management of the Built Environment - CRIT-RE-BUILT - held in Iasi, Romania, November 7-9, 2019.

The book describes emerging strategies to circumvent transmission and thermalization losses in solar cells, and thereby redefine the limits of solar power conversion efficiency.