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The focus of these conference proceedings is on research, development, and applications in the fields of numerical geometry, scientific computing and numerical simulation, particularly in mesh generation and related problems. In addition, this year¿s special focus is on Delaunay triangulations and their applications, celebrating the 130th birthday of Boris Delaunay.In terms of content, the book strikes a balance between engineering algorithms and mathematical foundations. It presents an overview of recent advances in numerical geometry, grid generation and adaptation in terms of mathematical foundations, algorithm and software development and applications.The specific topics covered include: quasi-conformal and quasi-isometric mappings, hyperelastic deformations, multidimensional generalisations of the equidistribution principle, discrete differential geometry, spatial and metric encodings, Voronoi-Delaunay theory for tilings and partitions, duality in mathematical programming and numerical geometry, mesh-based optimisation and optimal control methods. Further aspects examined include iterative solvers for variational problems and algorithm and software development. The applications of the methods discussed are multidisciplinary and include problems from mathematics, physics, biology, chemistry, material science, and engineering.

This book presents the Proceedings of The 6th Brazilian Technology Symposium (BTSym'20). The book discusses the current technological issues on Systems Engineering, Mathematics and Physical Sciences, such as the Transmission Line, Protein-Modified Mortars, Electromagnetic Properties, Clock Domains, Chebyshev Polynomials, Satellite Control Systems, Hough Transform, Watershed Transform, Blood Smear Images, Toxoplasma Gondi, Operation System Developments, MIMO Systems, Geothermal-Photovoltaic Energy Systems, Mineral Flotation Application, CMOS Techniques, Frameworks Developments, Physiological Parameters Applications, Brain¿Computer Interface, Artificial Neural Networks, Computational Vision, Security Applications, FPGA Applications, IoT, Residential Automation, Data Acquisition, Industry 4.0, Cyber-Physical Systems, Digital Image Processing, Patters Recognition, Machine Learning, Photocatalytic Process, Physical¿Chemical Analysis, Smoothing Filters, Frequency Synthesizers, Voltage-Controlled Ring Oscillator, Difference Amplifier, Photocatalysis, Photodegradation, current technological issues on Human, Smart and Sustainable Future of Cities, such as the Digital Transformation, Data Science, Hydrothermal Dispatch, Project Knowledge Transfer, Immunization Programs, Efficiency and Predictive Methods, PMBOK Applications, Logistics Process, IoT, Data Acquisition, Industry 4.0, Cyber-Physical Systems, Fingerspelling Recognition, Cognitive Ergonomics, Ecosystem Services, Environmental, Ecosystem Services Valuation, Solid Waste and University Extension.

This book, the first of its kind, surveys the career of the renowned Australian-German theatre and opera director Barrie Kosky. Its nine chapters provide multidisciplinary analyses of Barrie Kosky¿s working practices and stage productions, from the beginning of his career in Melbourne to his current roles as Head of the Komische Oper Berlin and as a guest director in international demand. Specialists in theatre studies, opera studies, musical theatre studies, aesthetics, and arts administration offer in-depth accounts of Kosky¿s unusually wide-ranging engagements with the performing arts ¿ as a director of spoken theatre, operas, musicals, operettas, as an adaptor, a performer, a writer, and an arts manager. Further, this book includes contributions from theatre practitioners with first-hand experience of collaborating with Kosky in the 1990s, who draw on interviews with members of Gilgul, Australiäs first Jewish theatre company, to document this formative period in Kosky¿s career. The book investigates the ways in which Kosky has created transnational theatres, through introducing European themes and theatre techniques to his Australian work or through bringing fresh voices to the national dialogue in Germany¿s theatre landscape. An appendix contains a timeline and guide to Kosky¿s productions to date.

This book provides researchers in the fields of organic chemistry, organometallic chemistry and homogeneous catalysis with an overview of significant recent developments in the area of metal-ligand cooperativity, with a focus on pincer architectures. The various contributions highlight the widespread impact of M¿L co-operativity phenomena on modern organometallic chemistry and catalyst development. The development of efficient and selective catalytic transformations relies on the understanding and fine control of the various elementary reactions that constitutes a catalytic cycle. Co-operative ligands, which actively participate in bond making and bond breaking together to the metal they support, open up new avenues in this area. In particular, buttressing a weak or reactive metal-ligand bond by flanking coordinating arms in a pincer ligand design is proving a versatile strategy to access robust metal complexes that exhibit unusual and selective reactivity patterns.

This book gathers the latest advances, innovations, and applications in urban and regional planning processes and science, as presented by international researchers at the 11th International Conference on Innovation in Urban and Regional Planning (INPUT), held in Catania, Italy, on September 8-10, 2021. The overarching theme of the conference INPUT 2021 was ¿Integrating Nature-Based Solutions in Planning Science and Practice¿, with contributes focusing on functionality of urban ecosystems toward more healthier and resilient cities, planning solutions for socio-ecological systems, technologies and hybrid models for spatial planning, geodesign, urban metabolism, computational planning, ecosystems services, green infrastructure, climate change adaptation and mitigation, rural landscapes, cultural heritage, and accessibility for urban planning. The conference brought together international scholars in the field of planning, civil engineering and architecture, ecology and social science, to build and consolidate the knowledge and evidence on NBS in urban and regional planning.

This book expands on the subject matter of ¿Computational Electromagnetics and Model-Based Inversion: A Modern Paradigm for Eddy-Current Nondestructive Evaluation.¿ It includes (a) voxel-based inversion methods, which are generalizations of model-based algorithms; (b) a complete electromagnetic model of advanced composites (and other novel exotic materials), stressing the highly anisotropic nature of these materials, as well as giving a number of applications to nondestructive evaluation; and (c) an up-to-date discussion of stochastic integral equations and propagation-of-uncertainty models in nondestructive evaluation. As such, the book combines research started twenty-five years ago in advanced composites and voxel-based algorithms, but published in scattered journal articles, as well as recent research in stochastic integral equations. All of these areas are of considerable interest to the aerospace, nuclear power, civil infrastructure, materials characterization and biomedical industries. The book covers the topic of computational electromagnetics in eddy-current nondestructive evaluation (NDE) by emphasizing three distinct topics: (a) fundamental mathematical principles of volume-integral equations as a subset of computational electromagnetics, (b) mathematical algorithms applied to signal-processing and inverse scattering problems, and (c) applications of these two topics to problems in which real and model data are used. It is therefore more than an academic exercise and is valuable to users of eddy-current NDE technology in industries as varied as nuclear power, aerospace, materials characterization and biomedical imaging.

The topic of this book, Collectins, is a family of proteins whose major function is in innate immunity, where Collectins act as pattern recognition receptors (PRRs). In general they recognize targets such as microbial surfaces and apoptotic cells, and once bound to a target, Collectins promote the clearance of microorganisms and damaged host tissue. New cell-surface proteins and glycoproteins, which act as Collectin receptors, are currently being identified. Some Collectins, particularly MBL, activate the complement system, which enhances the ability of antibodies to fight pathogens, via three MBL-associated proteases, the MASPs. Additionally, recent research has begun to show wider-ranging activities of Collectins, such as: · Their role in metabolism, and therefore their involvement in lifestyle diseases such as obesity and cardiovascular disease.· Their ability to modulate the adaptive immune response, as well as to recognize and trigger apoptosis of cancer cells, which makes them effective in the annihilation of cancer cells with multiple mutations.· The regulation of their expression by gonadal steroid hormones implicates them with critical roles in both male and female fertility.· Altered levels of Collectins have been associated with various autoimmune diseases.This book brings together current knowledge of the structure, functions and biological activities of Collectins, to describe their integral role in human health.

This book is open access under a CC BY 4.0 license.By 2050, human population is expected to reach 9.7 billion. The demand for increased food production needs to be met from ever reducing resources of land, water and other environmental constraints. Rice remains the staple food source for a majority of the global populations, but especially in Asia where ninety percent of rice is grown and consumed. Climate change continues to impose abiotic and biotic stresses that curtail rice quality and yields. Researchers have been challenged to provide innovative solutions to maintain, or even increase, rice production. Amongst them, the ¿green super rice¿ breeding strategy has been successful for leading the development and release of multiple abiotic and biotic stress tolerant rice varieties. Recent advances in plant molecular biology and biotechnologies have led to the identification of stress responsive genes and signaling pathways, which open up new paradigms to augment rice productivity. Accordingly, transcription factors, protein kinases and enzymes for generating protective metabolites and proteins all contribute to an intricate network of events that guard and maintain cellular integrity. In addition, various quantitative trait loci associated with elevated stress tolerance have been cloned, resulting in the detection of novel genes for biotic and abiotic stress resistance. Mechanistic understanding of the genetic basis of traits, such as N and P use, is allowing rice researchers to engineer nutrient-efficient rice varieties, which would result in higher yields with lower inputs. Likewise, the research in micronutrients biosynthesis opens doors to genetic engineering of metabolic pathways to enhance micronutrients production. With third generation sequencing techniques on the horizon, exciting progress can be expected to vastly improve molecular markers for gene-trait associations forecast with increasing accuracy. This book emphasizes on the areas of rice science that attempt to overcome the foremost limitations in rice production. Our intention is to highlight research advances in the fields of physiology, molecular breeding and genetics, with a special focus on increasing productivity, improving biotic and abiotic stress tolerance and nutritional quality of rice.

These proceedings of the 2018 XIII International Symposium on Spermatology focus on comparative biology, and encourages discussion and the exchange of ideas. The aim of this Symposium was to provide a unique opportunity and bring together scientists from a wide spectrum of research fields ¿ human, domestic animals and other mammals, vertebrates, insects, and plants. The underlying focus is on the function of the spermatozoon ¿ a common feature for sexual reproduction, but extremely varied. By exploring the variability, a better understanding of male reproductive functions can develop. These proceedings address the mechanisms of physiology and pathophysiology, rather than diagnosis and treatment. The symposium featured keynote lectures by invited speakers, followed by presentations on specific aspects of the general topic of the session. Experimental studies are given priority over clinical studies of patient populations. The proceedings comprise both keynote speakers' texts and selected free communications. Posters were considered for publication in the proceedings, and the volume includes exhibited materials on the work of prominent spermatologists, highlighting their important past achievements in the field.

Digital technologies are currently dramatically changing healthcare. This book introduces the reader to the latest digital innovations in healthcare in fields such as artificial intelligence, points out new ways in patient care and describes the limits of its application. It also offers essential guidance in the form of structured and authoritative contributions by domain experts spanning from artificial intelligence to hospital management to radiology to dentistry to preventive medicine. Furthermore, it shares ideas and experiences of industry veterans, in particular on how IT-driven solutions could solve long-standing issues in the fields of healthcare and hospitalization. It also gives advice on what new digital technologies to consider for becoming a healthcare market leader in the future. Taken together, these contributions provide a ¿road map¿ to guide decision makers, physicians, academics, industry representatives and other interested readers to understand the large impact of digital technology on healthcare today and its enormous potential for future development.

Integrated Science: Science without Borders¿ is the first volume of the INTEGRATED SCIENCE Book series, aiming to publish the results of the most updated ideas and reviews in transdisciplinary fields and to highlight the integration of discrete disciplines, including formal sciences, physical-chemical sciences and engineering, biological sciences, medical sciences, and social sciences. This volume primarily focuses on the research involving the integration of two or more academic fields offering an innovative, borderless view, which is one of the main focuses of the Universal Scientific Education and Research Network (USERN).The whole world is suffering from complex problems; these are borderless problems; thus, a borderless solution could merely solve such complex issues. Transdisciplinarity is a domain, that researchers work jointly, using a shared conceptual framework, drawing together disciplinary-specific theories, concepts, and approaches to address common problems. Lack of confidence, lack of expertise, complexities of healthcare, the confusing nature of healthcare environments, and lack of organization and standardization are the obstacles of successful scientific communication. Consequently, this book provides an overview of the essential elements of transdisciplinary studies and integrated science. The unique aspect of this book -privileging it from other books- is covering all aspects of science as harmonies of a single symphony.

This book presents state-of-the-art knowledge concerning water quality in Poland. It offers a wide variety of cases and issues on water resource quality management. The book also presents different methods and strategies to effectively use the most advanced water resource quality problems such as water pollution, whether physical, chemical, or biological, of surface water resources and groundwater resources.The authors pay exceptional attention to water quality monitoring in agricultural, urban catchments, and water reservoirs. More light into the water quality is required to assess water's physicochemical status accurately and plan suitable protection actions against recognized threats.This book addresses the needs of professional engineers, researchers, policy planners, decision-makers, stakeholders, and anyone looking to learn more about the quality situation of water resources in Poland and other similar countries and regions.

This volume covers various aspects of the fundamentals, synthesis, analysis, design, monitoring, and control of metals, materials, and metallurgical processes and phenomena. Topics represented include but are not limited to: ¿ Experimental, analytical, physical, and computer modeling of physical chemistry and thermodynamics ¿ Modeling of the transport phenomena in materials processing and metallurgical processes involving iron, steel, nonferrous metals, and composites ¿ Second-phase particles in metals and processes and the fundamentals (experimental studies or theoretical studies) on the nucleation, growth, motion, and removal of these particles from the molten metal or reactors ¿ Physical chemistry, thermodynamics, and kinetics for the production and refining of rare-earth metals ¿ Control of industrial processes in the field of extraction and processing of metals and materials

This volume summarises recent developments and highlights new techniques which will define possible future directions for small molecule X-ray crystallography. It provides an insight into how specific aspects of crystallography are developing and shows how they may interact or integrate with other areas of science.The development of more sophisticated equipment and the massive rise in computing power has made it possible to solve the three-dimensional structure of an organic molecule within hours if not minutes. This successful trajectory has resulted in the ability to study ever more complex molecules and use smaller and smaller crystals. The structural parameters for over a million organic and organometallic compounds are now archived in the most commonly used database and this wealth of information creates a new set of problems for future generations of scientists. The volume provides some insight into how users of crystallographic structural data banks can navigatetheir way through a world where ¿big datä has become the norm. The coupling of crystallography to quantum chemical calculations provides detailed information about electron distributions in crystals affording a much more detailed analysis of bonding than has been possible previously. In quantum crystallography, quantum mechanical wavefunctions are used to extract information about bonding and properties from the measured X-ray structure factors. The advent of quantum crystallography has resulted in form and structure factors derived from quantum mechanics which have been used in advanced refinement and wavefunction fitting. This volume describes how quantum mechanically derived atomic form factors and structure factors are constructed to allow the improved description of the diffraction experiment. It further discusses recent developments in this field and illustrates their applications with a wide range of examples.This volume will be of interest to chemists and crystallographers with an interest in the synthesis, characterisation and physical and catalytic properties of solid-state materials. It will also be relevant for the community of computational chemists who study chemical systems. Postgraduate students entering the field will benefit from a historical introduction to the way in which scientists have used the data derived from crystallography to develop new structural and bonding models.

This volume summarises recent developments and possible future directions for small molecule X-ray crystallography. It reviews specific areas of crystallography which are rapidly developing and places them in a historical context. The interdisciplinary nature of the technique is emphasised throughout. It introduces and describes the chemical crystallographic and synchrotron facilities which have been at the cutting edge of the subject in recent decades. The introduction of new computer-based algorithms has proved to be very influential and stimulated and accelerated the growth of new areas of science. The challenges which will arise from the acquisition of ever larger databases are considered and the potential impact of artificial intelligence techniques stressed. Recent advances in the refinement and analysis of X-ray crystal structures are highlighted.In addition the recent developments in time resolved single crystal X-ray crystallography arediscussed. Recent years have demonstrated how this technique has provided important mechanistic information on solid-state reactions and complements information from traditional spectroscopic measurements. The volume highlights how the prospect of being able to routinely ¿watch¿ chemical processes as they occur provides an exciting possibility for the future. Recent advances in X-ray sources and detectors that have also contributed to the possibility of dynamic single-crystal X-ray diffraction methods are presented. The coupling of crystallography and quantum chemical calculations provides detailed information about electron distributions in crystals and has resulted in a more detailed understanding of chemical bonding.The volume will be of interest to chemists and crystallographers with an interest in the synthesis, characterisation and physical and catalytic properties of solid-state materials. Postgraduate students entering the field will benefit from a historical introduction to the subject and a description of those techniques which are currently used. Since X-ray crystallography is used so widely in modern chemistry it will serve to alert senior chemists to those developments which will become routine in coming decades. It will also be of interest to the broad community of computational chemists who study chemical systems.

This book opens with an introduction to the main purpose and tasks of the GIANA challenge, as well as a summary and an analysis of the results and performance obtained by the 20 participating teams. The early and accurate diagnosis of gastrointestinal diseases is critical for increasing the chances of patient survival, and efficient screening is vital for locating precursor lesions. Video colonoscopy and wireless capsule endoscopy (WCE) are the gold-standard tools for colon and intestinal tract screening, respectively. Yet these tools still present some drawbacks, such as lesion miss rate, lack of in vivo diagnosis capabilities, and perforation risk. To mitigate these, computer-aided detection/diagnosis systems can play a key role in assisting clinicians in the different stages of the exploration.This book presents the latest, state-of-the-art approaches in this field, and also tackles the clinical considerations required to efficiently deploy these systems in the exploration room. The coverage draws upon results from the Gastrointestinal Image Analysis (GIANA) Challenge, part of the EndoVis satellite events of the conferences MICCAI 2017 and 2018. Each method proposed to address the different subtasks of the challenges is detailed in a separate chapter, offering a deep insight into this topic of interest for public health.This book appeals to researchers, practitioners, and lecturers spanning both the computer vision and gastroenterology communities.