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Wheat Quality for Improving Processing and Human Health brings together an international group of leading wheat scientists to outline highly relevant and diverse aspects and the latest advances in understanding of the world¿s most consumed cereal. Topics covered include LMW glutenins, starch-related proteins, and the impact of processing on composition and consumer health. Individual chapters focus on important factors such as FODMAPs, protein structure, dough viscoelasticity and fumonisins. The environmental effects on allergen content are comprehensively covered, as are phenolic compounds and molecular markers. The major quality screening tools and genetic resources are reviewed in depth. Gluten is a major focus of this work with chapters dedicated to health effects, analytical methods and standards, proteomics and mutant proteins. Starting in 2015, wheat quality scientists from across the globe have united to develop the Expert Working Group for Improving Wheat Quality for Processing and Health under the umbrella of the Wheat Initiative. This joint effort provides a framework to establish strategic research and organisation priorities for wheat research at the international level in both developed and developing countries. This Expert Working Group aims to maintain and improve wheat quality for processing and health under varying environmental conditions. The Group focuses on a broad range of wheat quality issues including seed proteins, carbohydrates, nutrition quality and micronutrient content, grain processing and food safety. Bioactive compounds are also considered, both those with negative effects such as allergens and mycotoxins, and those with positive effects such as antioxidants and fibre. The Group also works in the development of germplasm sets and other tools that promote wheat quality research.Wheat quality specialists working on the wheat value chain, and nutritionists will find this book a useful resourceto increase and update their knowledge of wheat quality, nutrition and health issues.

This book celebrates the contributions of John Weidman and his colleagues to the understanding of student socialization in higher education. It includes innovative chapters reflecting new approaches to higher education student socialization with respect to students of color, gender, STEM, and students in higher education systems outside the USA. Specifically, the book examines socialization between and within in a range of groups, including national, international and minority students, parents, doctoral students, early career faculty, and scholarly practitioners. The book assesses methodological approaches and suggests directions for reformulating theory and practice. Using sociological perspectives to address issues and concerns at both the undergraduate and graduate levels, the book gives renewed life to the college impact literature. It includes revisions and expansions of the original Weidman frameworks based on the synthesis of existing research with new work reflectingunique perspectives by a variety of authors. John Weidman has been an indisputable force in the study and understanding of student socialization in higher education. This new book by Weidman and his coeditor, Linda DeAngelo, represents an undeniably significant and welcomed expansion of the original ¿Weidman model¿ of student socialization. In updating and revising the original model, chapter authors give attention to various contemporary issues such as student diversity, gender differences, early career experiences, and internationalism. Whether one samples only some of the articles that constitute this book or reads all of them, the professional payoff will be substantial. Kenneth A. Feldman, Professor of Sociology, Stony Brook UniversityJohn Weidman has made a number of groundbreaking contributions to our understanding of student socialization in postsecondary education. This book, edited with Linda DeAngelo, brings together a group of fine scholars whose contributions will push our understanding even further. It is a significant addition to the college impact literature.Ernest T. Pascarella, Petersen Chair in Higher Education, University of Iowa

This edited volume offers solutions on the challenges of religious pluralisation from a European perspective. It gives special attention to interreligious dialogue and interfaith relations as specific means of dealing with plurality. In particular, the contributors describe innovative scientific approaches and broad political and social scopes of action for addressing the diversity of beliefs, practices, and traditions. In total, more than 25 essays bring together interdisciplinary and international research perspectives. The papers cover a wide thematic range. They highlight how religious pluralisation effects such fields as theology, politics, civil society, education, and communication/media. The contributors not only illustrate academic debates about religious diversity but they also look at the political and social scope for dealing with such. Coverage spans numerous countries, and beliefs, from Buddhism to Judaism.This book features presentationsfrom the Herrenhausen Conference on "Religious Pluralisation - A Challenge for Modern Societies," held in Hanover, Germany, October 2016. This insightful collection will benefit students and researchers with an interest in religion and laicism, interreligious dialogue, governance of religious diversity, and religion in the public sphere.

The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T-cell engager (BITES), Dual Variable Domain (DVD) antibodies, and fusion proteins that are currently being used as therapeutic agents for immunology, oncology and other disease conditions. Regulatory agencies have raised the bar for the development and manufacture of antibody-based products, expecting to see the use of Quality by Design (QbD) elements demonstrating an in-depth understanding of product and process based on sound science. Drug delivery systems have become an increasingly important part of the therapy and most biopharmaceuticals for self-administration are being marketed as combination products. A survey of the market indicates that there is a strong need for a new book that will provide ¿one stop shopping¿ for the latest information and knowledge of the scientific and engineering advances madeover the last few years in the area of biopharmaceutical product development. The new book entitled Development of Biopharmaceutical Drug Device Products is a reference text for scientists and engineers in the biopharmaceutical industry, academia or regulatory agencies. With insightful chapters from experts in the field, this new book reviews first principles, covers recent technological advancements and provides case studies and regulatory strategies relating to the development and manufacture of antibody-based products. It covers topics such as the importance of early preformulation studies during drug discovery to influence molecular selection for development, formulation strategies for new modalities, and the analytical techniques used to characterize them. It also addresses important considerations for later stage development such as the development of robust formulations and processes, including process engineering and modeling of manufacturing unit operations, the design of analytical comparability studies, and characterization of primary containers (pre-filled syringes and vials).Finally, the latter half of the book reviews key considerations to ensure the development and approval of a patient-centered delivery system design. This involves the evolving regulatory framework with perspectives from both the US and EU industry experts, the role of international standards, design control/risk management, human factors and its importance in the product development and regulatory approval process, as well as review of the risk-based approach to bridging between devices used in clinical trials and the to-be-marketed device. Finally, case studies are provided throughout.The typical readership would have biology and/or engineering degrees and would include researchers, scientific leaders, industry specialists and technology developers working in the biopharmaceutical field.

This textbook provides a thorough introduction and overview of the design and engineering of state-of-the-art prosthetics and assistive technologies. Innovations in prosthetics are increasingly made by cross-disciplinary thinking, and the author introduces the application of biomedical, mechanical, electrical, computer, and materials engineering principles to the design of artificial limbs. Coverage includes the fundamentals of biomechanics, biomechanical modeling and measurements, the basics of anatomy and physiology of limb defects, and the historical development of prosthetic design. This book stimulates the innovative thinking necessary for advancing limb restoration, and will be essential reading for students, as well as researchers, professional engineers and prosthetists, involved in the design and manufacture of artificial limbs.Learning enhanced by the exercises, including physical modeling with MATLAB and Simulink;Includes appendices with relevant equations and parameters for reference;Introduction to the design and engineering of prosthetics and assistive technologies.

Data processing has become essential to modern civilization. The original data for this processing comes from measurements or from experts, and both sources are subject to uncertainty. Traditionally, probabilistic methods have been used to process uncertainty. However, in many practical situations, we do not know the corresponding probabilities: in measurements, we often only know the upper bound on the measurement errors; this is known as interval uncertainty. In turn, expert estimates often include imprecise (fuzzy) words from natural language such as "small"; this is known as fuzzy uncertainty. In this book, leading specialists on interval, fuzzy, probabilistic uncertainty and their combination describe state-of-the-art developments in their research areas. Accordingly, the book offers a valuable guide for researchers and practitioners interested in data processing under uncertainty, and an introduction to the latest trends and techniques in this area, suitablefor graduate students.

This volume provides a comprehensive overview of the major applications and potential of fungal biotechnology. The respective chapters report on the latest advances and opportunities in each topic area, proposing new and sustainable solutions to some of the major challenges faced by modern society. Aimed at researchers and biotechnologists in academia and industry, it represents essential reading for anyone interested in fungal biotechnology, as well as those working within the broader area of microbial biotechnology. Written in an accessible language, the book also offers a valuable reference resource for decision-makers in government and at non-governmental organizations who are involved in the development of cleaner technologies and the global bioeconomy. The 21st century is characterized by a number of critical challenges in terms of human health, developing a sustainable bioeconomy, facilitating agricultural production, and establishing practices that support a cleanerenvironment. While there are chemical solutions to some of these challenges, developing bio-based approaches is becoming increasingly important. Filamentous fungi, ¿the forgotten kingdom,¿ are a group of unique organisms whose full potential has yet to be revealed. Some key properties, such as their exceptional capacity to secrete proteins into the external environment, have already been successfully harnessed for the production of industrial enzymes and cellulosic biofuels. Many further aspects discussed here ¿such as feeding the hungry with fungal protein, and the potential applications of the various small molecules produced by fungi ¿warrant further exploration. In turn, the book covers the use of fungal cell factories to produce foreign molecules, e.g. for therapeutics. Strategies including molecular approaches to strain improvement, and recent advances in high-throughput technologies, which are key to finding better products and producers, are also addressed. Lastly, the book discusses the advent of synthetic biology, which is destined to greatly expand the scope of fungal biotechnology.The chapter ¿Fungal Biotechnology in Space: Why and How?¿ is available open access under a Creative Commons Attribution 4.0 International License at link.springer.com.