Bøker utgitt av Springer Nature Singapore

Electromagnetic Meson Production at Low Energies; B.H. Schoch. Parity Violation in Electron Scattering; R.D. McKeown. Polarization in Leptoninduced Reactions; T.W. Donnelly. Quark Structure of the Nucleon and Nucleon Resonances; B. Metsch. Leptonic Production of Baryon Resonances; V.D. Burkert. Structure Functions of the Nucleon; T.J. Ketel. Nuclear Filtering and Quantum Color Transparency: An Introductory Review; J.P. Ralston. Photon and Meson Production in Ultrarelativistic Nucleus-Nucleus Collisions; H. Löhner. Near Threshold Particle Production: A Probe of Resonancematter Formation in Heavy-ion Collisions; V. Metag. Quark Matter and Nuclear Collisions; H. Satz. The String Model of Nuclear Scattering: Theoretical Concepts; K. Werner. Introduction to the Dual Parton Model; A. Capella. Nucleon-Nucleon Bremsstrahlung; K. Nakayama. Index.

Thermal Stability and the Suppression of Convection in a Rotating Fluid on Earth; W.A. Arnold, L.L. Regel. Convective Flows during Crystal Growth in a Centrifuge; V.A. Urpin. Removal of Convective Instabilities in Liquid Metals by Centrifugation; A. Chevy, et al. Growth of GaAs Single Crystals at High Gravity; B. Zhou, et al. Response of Temperature Oscillations in a Tin Melt to Centrifugal Effects; W.J. Ma, et al. Unsteady Thermal Convection of Melts in a 2D Horizontal Boat in a Centrifugal Field with Consideration of the Coriolis Effect; F. Tao, et al. Variation of Effective Impurity Segregation Coefficient in Tellurium Grown under High Gravity; I.I. Farbshtein, et al. Analysis of Impurity Distribution by Galvanomagnetic Method in InSb Obtained under High Gravity Conditions; I.I. Farbshtein, et al. Microstructural Development in PbSn Alloys Subjected to Highgravity during Controlled Directional Solidification; R.N. Grugel, et al. The Role of Thermal Stress in Vertical Bridgman Growth of CdZnTe Crystals; T. Lee, et al. Morphological Stability of Directional Solidification in a Centrifugal Field; V.S. Yuferev. 11 additional articles. Index.

Is There a Link between the Nature of Agents That Trigger Mast Cells and the Induction of Immunoglobulin (IG)E Synthesis?.- Immunogenetic Aspects of IgE-Mediated Responses.- Structure and Function of the Low Affinity IgE Receptor.- Characterization of the Human IgE Fc-Fce RIa Interaction.- The Analysis of Mast Cell Function in Vivo Using Mast Cell-Deficient Mice.- The Immunogenetic Basis of Collagen Induced Arthritis in Mice: An Experimental Model for the Rational Design of Immunomodulatory Treatments of Rheumatoid Arthritis.- Suppression of Experimental Autoimmune Myasthenia Gravis by Epitope-Specific Neonatal Tolerance.- T Cell Reactivity to Self and Allogeneic MHC-Peptides.- Antiribosomal Antibodies in SLE, Infection, and Following Deliberate Immunization.- Cross-Reactions of Anti-Immunoglobulin Sera with Synthetic T-Cell Receptor ? Peptides: Mapping on a 3-Dimension Model.- Stress Proteins in Autoimmunity.- Polyclonal B Cell Activation and B Cell Cross-Reactivity During Autoantibody Production in Systemic Lupus Erythematosus.- Autoantibody Activity and V Gene Usage by B-Cell Malignancies.- Naturally Occurring Human Autoantibodies to Defend T-Cell Receptor and Light Chain Peptides.- Natural Autoantibodies.- Regulatory Autoantibody and Cellular Aging and Removal.- B-Cell Origin of Cold Agglutinins.- Initiation of Autoimmune Type 1 Diabetes and Molecular Cloning of a Gene Encoding for Islet Cell-Specific 37KD Autoantigen.- Mapping of the Polypeptide Chain Organization of the Main Extracellular Domain of the ?-Subunit in Membrane-Bound Acetylcholine Receptor by Anti-Peptide Antibodies Spanning the Entire Domain.

QoS Enhancements and the New Transport Services; A. Danthine, et al. Performance Evaluation and Monitoring of Heterogenous Networks; J. Neuman, et al. Application of High Speed Networks in Hospital Environment; J.R. Rao. On Allocation Schemes for the Interconnection of LANs and Multimedia Sources over Broadband Networks; M. Mateescu. A Superposition of Bursty Sources in a LAN Interconnection Environment; J.M. Karlsson. Interconnecting LANs for Real Time Traffic Application; I. Chlamtac. An Analytical Model for ATM Based Networks which Utilize LookAhead Contention Resolution Switching; J.V. Luciani, C.Y. Roger Chen. Transient Analysis of Nonhomogenous Continuous Time Markov Chains Describing Realistic LAN Systems; A. Rindos, et al. Closed Queueing Network Modeling for End-to-End Performance Analysis of ISO LLC Transport Protocols over Bridged Networks; T. Ikegawa. A Preview of APPN High Performance Routing; J.P. Gray, M.L. Peters. 12 additional articles. Index.

Structure, Expression, and Regulation of the IGF-I Gene.- Differential Regulation of IGF-I Leader Exon Transcription.- Insulin and IGF-I Analogs: Novel Approaches to Improved Insulin Pharmacokinetics.- Analysis of the Interaction of Igf-I Analogs with the IGF-I Receptor and IGF Binding Proteins.- Synthesis and Characterization of IGF-II Analogs: Applications in the Evaluation of IGF Receptor Function and IGF-Independent Actions of IGFBPS.- Towards Identification of a Binding Site on Insulinlike Growth Factor-II for IGF-Binding Proteins.- Transcriptional and Post-Transcriptional Regulation of the Human IGF-II Gene Expression.- Significant Species Differences in Local IGF-I and -II Gene Expression.- Transcriptional Regulation of the Insulin Receptor Gene Promoter.- The Regulation of IGF-I Receptor Gene Expression by Positive and Negative Zinc-Finger Transcription Factors.- Cell Cycle Control by the IGF-1 Receptor and Its Ligands.- The Insulin Receptor Family.- IRR: a Novel Member of the Insulin Receptor Family.- Molecular Properties of Insulin/IGF-1 Hybrid Receptors.- Immunological Studies of Type I IGF Receptors and Insulin Receptors: Haracterisation of Hybrid and Atypical Receptor Subtypes.- Insulin like Growth Factor 1 Receptor Signal Transduction to the Nucleus.- Molecular Cloning of pp120/ ECTO-ATPase, An Endogenous Substrate of the Insulin Receptor Kinase.- The Insulin-like Growth Factor-II/mannose-6-Phosphate Receptor: Structure, Function and Differential Expression.- Parental Imprinting of the Genes for IGF-II and Its Receptor.- Multihormonal Regulation of IGFBP-1 Promoter Activity.- Insulin-like Growth Factor Binding Protein-1: Identification, Purification, and Regulation in Fetal and Adult Life.- Rapid Regulation of Insulin-like Growth Factor Binding Protein-1 Transcription by Insulin In Vito and In Vivo.- IGF Binding Protein-3 and the ACID-labile Subunit: Formation of the Ternary Complex In Vitro and In Vivo.- Role of Post Translational Modifications in Modifying the Biologic Activity of Insulin like Growth Factor Binding Proteins.- Cellular Actions of Insulin-like Growth Factor Binding Protein-3.- Gene Expression of the IGF Binding Proteins during Post-Implantation Embryogenesis of the Mouse: Comparison with the Expression of IGF-I and -II and Their Receptors in Rodent and Human.- Hormonal Regulation of Insulin-like Growth Factor Binding Protein-1 Expression and the Development of Transgenic Mouse Models to Study IGFBP-1 Function.- Limited Proteolysis of Insulin-like Growth Factor Binding Protein-3 (IGFBP-3): A Physiological Mechanism in the Regulation of IGF Bioavailability.- Effects of Insulin-like Growth Factor 1 (IGF-I) Administrations on Serum IGF Binding Proteins (IGFBPS) in Patients with Growth Hormone Deficiency.- Metabolic Effects of rhIGF-1 in Normal Human Subjects.- IGFS and Muscle Differentiation.- IGF-II in the Pathogenesis of Rhabdomyosarcoma: a Prototype of IGFS Involvement in Human Tumorigenesis.- The Physiology and Pathophysiology of IGF-I in the Kidney.- Regulation of IGFBP-4 and -5 Expression in Rat Granulosa Cells.- Insulin-like Growth Factor (IGF) Binding Protein-1 Is an Antigonadotropin: Evidence that Optimal Follicle-Stimulating Hormone Action in Ovarian Granulosa Cells Is Contingent upon Amplification by Endogenously-Derived IGFS.- Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Proteins in the Zucker Fatty Rat: a case for Differential Tissue Regulation.- Characterization of the IGF Regulatory System in Bone.- Regulation of IGF Activity in Bone.

Cell to Organ: Electromechanical Activation.- 1 Regulation of Intracellular Calcium in Cardiac Muscle.- 2 Neuromodulation of Calcium Current by Extracellular ATP in Isolated Ventricular Myocytes.- 3 Intracellular Calcium and Myocardial Function during Ischemia.- 4 Intracellular Signaling in Vascular Smooth Muscle.- 5 Myocardial Energetics.- 6 Mechanisms of Endocardial Endothelium Modulation of Myocardial Performance.- 7 Calcium Kinetic and Mechanical Regulation of the Cardiac Muscle.- 8 Cellular Responses to Electrical Stimulation: A Study Using a Model of the Ventricular Cardiac Action Potential.- 9 Excitation-Contraction Coupling and Contractile Protein Function in Failing and Nonfailing Human Myocardium.- Mechanics and Microcirculation.- 10 Estimation of Myocardial Mechanical Properties with Dynamic Transverse Stiffness.- 11 Intramyocardial Mechanical States: Vessel-Interstitium-Muscle Interface.- 12 Myocardial Mechanics and Coronary Flow Dynamics.- 13 Modeling of Coronary Capillary Flow.- Microstructure: Mechanics and Microcirculation.- 14 Models for Coronary Pressure-Flow Relationships.- 15In VivoMyocardial Microcirculation: Evaluation with a Whole-Body X-Ray CT Method.- 16 Endocardial Coronary Microcirculation of the Beating Heart.- 17 Distribution and Control of Coronary Microvascular Resistance.- 18 Theoretical Analysis of Coronary Blood Flow and Tissue Oxygen Pressure-Control.- Microcirculation and Metabolic Transport.- 19 Adenosine Coronary Vasodilation during Hypoxia Depends on Adrenergic Receptor Activation.- 20 Chaos in Cardiac Signals.- 21 Intramyocardial Fluid Transport Effects on Coronary Flow and Left Ventricular Mechanics.- 22 Metabolic Protection of Post-Ischemic Phosphorylation Potential and Ventricular Performance.- 23 Metabolic and Mechanical Control of the Microcirculation.- Remodeling of Muscle and Vessels.- 24 Asymmetrical Changes in Ventricular Wall Mass by Asynchronous Electrical Activation of the Heart.- 25 Ventricular Remodeling after Myocardial Infarction.- 26 Arterial Remodelling after Percutaneous Transluminal Balloon Angioplasty.- 27 Structural and Functional Remodeling of Poststenotic Arteries in the Rat.- 28 Myocardial Collagen and Its Functional Role.- Cardiac Function and Circulation.- 29 Ventricular-Arterial Interaction: Cardiac Effects of Mean versus Pulsatile Arterial Load.- 30 The Veins and Ventricular Preload.- 31 Why Smaller Animals Have Higher Heart Rates.- 32 Feedback Effects in Heart-Arterial System Interaction.- Integrated Analysis.- 33 The Relationship between Altered Load and Impaired Diastolic Function in Conscious Dogs with Pacing Induced Heart Failure.- 34 Interactions: The Integrated Functioning of Heart and Lungs.- 35 Carotid-Cardiac Interaction: Heart Rate Variability during the Unblocking of the Carotid Artery.- 36 Right and Left Ventricle Interaction and Remodeling in Congenital Heart Disease.- 37 Macroscopic Three-Dimensional Motion Patterns of the Left Ventricle.- 38 Cardiovascular Flow Velocity Measurements by 2D Doppler Imaging for Assessment of Vascular Function.- The Editors.- Contributors.

Fluoropyrimidine Metabolism and Mechanism of Action.- 5-Fluoro-2?-Deoxyuridine: Role of Schedule in its Therapeutic Efficacy.- Comparison of Continuous Infusions and Bolus Injections of 5- Fluorouracil with or without Leucovorin: Implications for Inhibition of Thymidylate Synthase.- Critical Questions for the Future Direction of FU/LV.- Cellular Interactions Between the Natural and Unnatural Isomers of 5-Formyltetrahydrofolate.- Leucovorin as a Prodrug.- Clinical Use of Leucovorin: Intracellular Metabolism.- Some Considerations Concerning the Dose and Schedule of 5FU and Leucovorin: Toxicities of Two Dose Schedules from the Intergroup Colon Adjuvant Trial (INT-0089).- Effects of 5-Fluorouracil on mRNA.- Genetic Variation in Thymidylate Synthase Confers Resistance to 5-Fluorodeoxyuridine.- Experience with 5FU + L-Leucovorin.- 5-Fluorouracil Combined with the Pure [6S]-Stereoisomer of Folinic Acid in High Doses for Treatment of Patients with Advanced Colorectal Carcinoma: A Phase I-II Study of Two Consecutive Regimens.- 5-Fluorouracil Modulation in Colorectal Carcinoma: Experience of German Investigators.- An Overview of Adjuvant Treatment of Colon Cancer.- Dose-Dependent Inhibition of Aspartate Carbamoyltransferase in Peripheral Blood Mononuclear Cells in Patients Receiving N-Phosphonacetyl)-L-Aspartate.- Alternative Approaches to Modulation of Fluoropyrimidines.- Increasing the Efficacy of 5-Fluorouracil with Interferons: Preclinical, Clinical, and Pharmacokinetic Studies.- Enchanced Cytotoxicity of 5-Fluorouracil Combined with [6RS]-Leucovorin and Recombinant Human Interferon-?2a in Colon Carcinoma Cells.- Regulation of Thymidylate Synthase in Human Colon Cancer Cells Treated with 5-Fluorouracil and Interferon-Gamma.- Biochemical Modulation of 5-Fluorouracil by PALA: Mechanism of Action.- Implications of Chronobiology for 5-Fluorouracil (5-FU) Efficacy.- Update on Metabolic Modulation as a Therapeutic Approach for Adult Carcinomas.- Fluorouracil and Leucovorin in Advanced Breast Cancer.- Fluorouracil Modulation in Head and Neck Cancer.- Biomodulation in Head and Neck Carcinomas: Therapeutic Approaches in Europe.- Rationale for the Combination Therapy of 5FU and CDDP.- Biochemical Modulation of Fluoropyrimidines: The "Giscad" Studies.- New Drugs.- Clinical Experience with UFT in Japan.- Clinical Studies of the Modulation of Ftorafur.- The Role of the Reduced-Folate Carrier and Metabolism to Intracellular Polyglutamates for the Activity of ICI D1694.- The History of the Development and Clinical Use of CB 3717 and ICI D1694.- New Sites of Intervention in the Development of New Drugs in Solid Tumors.- P53: A Determinant of the Cell Cycle Response to DNA Damage.- Therapeutic Implications of Molecular Genetics.- Concluding Remarks.- Summary.- Abbreviations.- Author Index.

1-Coronavirus Genes: Comparative Aspects.- Sequence Analysis of CCV and its Relationship to FIPV, TGEV and PRCV.- Genomic Organization and Expression of the 3' End of the Canine and Feline Enteric Coronaviruses.- Cloning and Sequence Analysis of the Spike Gene from Several Feline Coronaviruses.- Genomic Organisation of a Virulent Taiwanese Strain of Transmissible Gastroenteritis Virus.- The Use of PCR Genome Mapping for the Characterisation of TGEV Strains.- Evolution and Tropism of Transmissible Gastroenteritis Coronavirus.- Transmissible Gastroenteritis Virus and Porcine Respiratory Coronavirus: Molecular Characterization of the S Gene Using cDNA Probes and Nucleotide Sequence Analysis.- Sequence Analysis of the Nucleocapsid Protein Gene of Porcine Epidemic Diarrhoea Virus.- Genome Organization of Porcine Epidemic Diarrhoea Virus.- Characterization of the Nonstructural and Spike Proteins of the Human Respiratory Coronavirus OC43: Comparison with Bovine Enteric Coronavirus.- Identification, Expression in E. coli and Insect Cells of the Non-Structural Protein NS2 Encoded by mRNA2 of Bovine Coronavirus (BCV).- Characterization of the Human Coronavirus 229E (HCV 229E) Gene 1.- Identification of Coronaviral Conserved Sequences and Application to Viral Genome Amplification.- 2-Transcription, Replication and Genome Engineering.- Studies into the Mechanism for MHV Transcription.- Analysis of the Cis-Acting Elements of Coronavirus Transcription.- Control of TGEV mRNA Transcription.- An Intraleader Open Reading Frame is Selected from a Hypervariable 5' Terminus During Persistent Infection by the Bovine Coronavirus.- Effects of Mouse Hepatitis Virus Infection on Host Cell Metabolism.- The Effect of Amantadine on Mouse Hepatitis Virus Replication.- Analysis of Messenger RNA within Virions of IBV.- Inhibition of Mouse Hepatitis Virus Multiplication by Antisense Oligonucleotide, Antisense RNA, Sense RNA and Ribozyme.- Site-Specific Sequence Repair of Coronavirus Defective Interfering RNA by RNA Recombination and Edited RNA.- Site-Directed Mutagenesis of the Genome of Mouse Hepatitis Virus by Targeted RNA Recombination.- Homologous RNA Recombination Allows Efficient Introduction of Site-Specific Mutations into the Genome of Coronavirus MHV-A59 via Synthetic Co-Replicating RNAs.- 3-Characterization and Functions of Viral Proteins.- Identification of Peplomer Cleavage Site Mutations Arising During Persistence of MHV-A59.- Proteolytic Cleavage of the Murine Coronavirus Surface Glycoprotein is not Required for its Fusion Activity.- Fusogenic Properties of Uncleaved Spike Protein of Murine Coronavirus JHMV.- Characterization of a Monoclonal Antibody Resistant Variant of MHV.- Molecular Mimicry Between S Peplomer Proteins of Coronaviruses (MHV, BCV, TGEV and IBV) and Fc receptor.- Complex Formation Between the Spike Protein and the Membrane Protein During Mouse Hepatitis Virus Assembly.- Preliminary Characterization of a Monoclonal Antibody Specific for a Viral 27 kD Glycoprotein Family Synthesized in Porcine Epidemic Diarrheoa Virus Infected Cells.- Involvement of Lipids in Membrane Binding of Mouse Hepatitis Virus Nucleocapsid Protein.- A Novel Glycoprotein of Feline Infectious Peritonitis Coronavirus Contains a KDEL-Like Endoplasmic Reticulm Retention Signal.- Altered Proteolytic Processing of the Polymerase Polyprotein in RNA(-) Temperature Sensitive Mutants of Mucine Coronavirus.- A Newly Identified MHV-A59 ORF1a Polypeptide p65 is Temperature Sensitive in Two RNA Negative Mutants.- Proteolytic Processing of the N-Terminal Region of the Equine Arteritis Virus Replicase.- 4-Coronaviruses, Toroviruses and Arteriviruses: Common and Distinctive Features.- The Coronaviruslike Superfamily.- Equine Arteritis Virus (EAV) Contains a Unique Set of Four Structural Proteins.- The Coronaviridae now Comprises Two Genera, Coronavirus and Torovirus: Report of the Coronaviridae Study Group.- 5-Cellular Receptors for Coronaviruses.- Coronavirus Receptor S...

Mathematics and Physics 1: New Ways to Use Old Ideas for High Quality Acoustic Images; G. Wade. Mathematics and Physics 2: A Modified Algorithm for Ultrasound Holographic Q Imaging; Q. Zhengdi. Application in Nondestructive Testing: Imaging and Inverse Scattering in Nondestructive Evaluation; K.J. Langenberg, et al. Acoustical and Optoacoustical Microscope: Nearfield Scanning Acoustic Microscopy; A. Kulik, et al. Transducers and Array: Formation and Propagation of Limited Diffraction Beams; J. Lu, J.F. Greenleaf. Application in Medicine and Biology 1: Multidimensional Cardiac Imaging; J.F. Greenleaf, et al. Application in Medicine and Biology 2: A Restoration Method of Ultrasonic Medical Tomogram; K. Zhou, et al. Seismic Imaging: A Method of Diffraction Tomography; K. Nagai, et al. Underwater Acoustical Imaging: A New Generation Side Scan Sonar; P. Alais, et al. 96 additional articles. Index.

1 Vascular Analysis of the Carotid Body in the Spontaneously Hypertensive Rat.- 2 Role of the Carotid Sinus Nerve and of Dopamine in the Biochemical Response of Sympathetic Tissues to Long-Term Hypoxia.- 3 The Effects of Almitrine on [3H]5HT and [125I] Endothelin Binding to Central and Peripheral Receptors: An In Vitro Autoradiographic Study in the Cat.- 4 Immunocytochemical and Neurochemical Aspects of Sympathetic Ganglion Chemosensitivity.- 5 Neuronal and Neuroendocrine Markers in the Human Carotid Body in Health and Disease.- 6 The Effects of Chronic Hypoxaemia upon the Structure of the Human Carotid Body.- 7 Dopaminergic and Peptidergic Sensory Innervation of the Rat Carotid Body: Organization and Development.- 8 Effects of Cell-Free Perfusion and Almitrine Bismesylate on the Ultrastructure of Type-1 Cell Mitochondria in the Cat Carotid Body.- 9 Multi-Unit Compartmentation of the Carotid Body Chemoreceptor by Perineurial Cell Sheaths: Immunohistochemistry and Freeze-Fracture Study.- 10 Light and Electronmicroscopical Immunohistochemical Investigation of the Innervation of the Human Carotid Body.- 11 Serotonin (5-Hydroxytryptamine) Expression in Pulmonary Neuro-Endocrine Cells (NE) and a Netumor Cell Line.- 12 Effects of Hypoxia on Cultured Chemoreceptors of the Rat Carotid Body: DNA Synthesis and Mitotic Activity in Glomus Cells.- 13 Localization of Dopamine D2 Receptor mRNA in the Rabbit Carotid Body and Petrosal Ganglion by in situ Hybridization.- 14 Noradrenergic Glomus Cells in the Carotid Body: An Autoradiographic and Immunocytochemical Study in the Rabbit and Rat.- 15 The Modulation of Intracellular pH in Carotid Body Glomus Cells by Extracellular pH and pCO2.- 16 Evidence for Glucose Uptake in the Rabbit Carotid Body.- 17 Effects of Inorganic Calcium Channel Blockers on Carotid Chemosensory Responses in the Cat.- 18 Those Strange Glomus Cells.- 19 Carotid Body Neurotransmission.- 20 Carbonic Anhydrase and the Carotid Body.- 21 Ca2+ Dynamics in Chemoreceptor Cells: An Overview.- 22 Spectrophotometric Analysis of Heme Proteins in Oxygen Sensing Cell Systems.- 23 Neurochemical and Molecular Biological Aspects on the Resetting of the Arterial Chemoreceptors in the Newborn Rat.- 24 Carbonic Anhydrase and Carotid Body Chemoreception in the Presence and Absence of CO2-HCO3-.- 25 Role of Ion-Exchangers in the Cat Carotid Body Chemotransduction.- 26 Dopamine Metabolism in the Rabbit Carotid Body in vitro: Effect of Hypoxia and Hypercapnia.- 27 PO2-Dependence of Phospholipase C in the Cat Carotid Body.- 28 Optical Measurements of Micro-Vascular Oxygen Pressure and Intracellular pH in the Cat Carotid Body: Testing Hypotheses of Oxygen Chemoreception.- 29 Elevation of Cytosolic Calcium Induced by pH Changes in Cultured Carotid Body Glomus Cells.- 30 Role of Carbon Dioxide for Hypoxic Chemotransduction of the Cat Carotid Body.- 31 Metabolic Substrate Dependence of Carotid Chemosensory Responses to Stop-Flow Evoked Hypoxia and to Nicotine.- 32 Effects of Chemosensory Stimulation Membrane Currents Recorded with the Perforated-Patch Method from Cultured Rat Glomus Cells.- 33 Carbonic Anhydrase Near Central Chemoreceptors.- 34 Update on the Bicarbonate Hypothesis.- 35 Regulation of Intracellular pH in Type I Cells of the Neonatal Rat Carotid Body.- 36 Noradrenergic Inhibition of the Goat Carotid Body.- 37 Role of Substance P in Rat Carotid Body Responses to Hypoxia and Capsaicin.- 38 Carotid Sinus Nerve Inhibition Mediated by Atrial Natriuretic Peptide.- 39 Neurotransmitters and Second Messenger Systems in the Carotid Body.- 40 Does Adenosine Stimulate Rat Carotid Body Chemoreceptors?.- 41 Effects of Haloperidol on Cat Carotid Body Chemoreceptionin Vitro.- 42 Effect of Arterial Chemoreceptor Stimulation: Role of Norepinephrine in Hypoxic Chemotransmission.- 43 Carotid Body Denervation and Pulmonary Vascular Resistance in the Rat.- 44 Effects of Chemoreceptor Stimulation by Almitrine Bismesylate on Renal Function in Conscious Rats...

Chemistry. Tetrahydrobiopterin Dependent Hydroxylases. Tetrahydrobiopterin Regenerating Enzymes. Tetrahydrobiopterin Biosynthesis. Tetrahydrobiopterin Regulation. Tetrahydrobiopterin Deficiency. Nitric Oxide Synthase. Other Functions of Tetrahydrobiopterins. Molybdopterin Cofactors. Synthesis and Biological Evaluation of AntiFolates. Dihydrofolate Reductase. Thymidylate Synthase. Folylpolyglutamate Synthetase and Hydrolase. OneCarbon Metabolism. Folate Nutrition and Transport. 165 articles. Index.

Regulation of Insulin Secretion.- Impaired Glucose-Induced Insulin Secretion: Studies in Animal Models with Spontaneous NIDDM.- Perturbation of Islet Metabolism and Insulin Release in NIDDM.- Regulation of Cytoplasmic Free Ca2+ in Insulin-Secreting Cells.- The ß-Cell Sulfonylurea Receptor.- Insulin, Insulin Receptors and Glucose Transporters.- Regulation of Glucose Transporters and the Na/K-ATPase by Insulin in Skeletal Muscle.- Insulin Receptor: Aspects of Its Structure and function.- The Diabetogenes Concept of NIDDM.- Molecular Genetics of NIDDM and the Genes for Insulin and Insulin Receptor.- Autoregulation of Glucose Transport: Effects of Glucose on Glucose Transporter Expression and Cellular Location in Muscle.- Insulin Action in NIDDM.- Insulin Resistance and the Pathogenesis of Non-Insulin Dependent Diabetes Mellitus: Cellular and Molecular Mechanisms.- Indirect Effects of Insulin in Regulating Glucose Fluxes.- The Insulin-Antagonistic Effect of the Counterregulatory Hormones - Clinical and Mechanistic Aspects.- On Insulin Action in Vivo: The Single Gateway Hypothesis.- Gluconeogenesis.- Acute Hormonal Regulation of Gluconeogenesis in the Conscious Dog.- Estimating Gluconeogenic Rates in NIDDM.- Glucose Metabolism during Physical Exercise in Patients with Noninsulin-Dependent (Type II) Diabetes.- Substrates and the Regulation of Hepatic Glycogen Metabolism.- Gluconeogenesis in Type 2 Diabetes.- Obesity, Lipoproteins, Atherogenesis, and NIDDM.- Regulation of Adipose Tissue Lipolysis, Importance for the Metabolic Syndrome.- Cellular and Molecular Factors in Adipose Tissue Growth and Obesity.- Regional Obesity and NIDDM.- Hyperinsulinemia and VLDL Kinetics.- Hyperinsulinism and Dyslipidemias as Coronary Heart Disease Risk Factors in NIDDM.- Potential Impact of New Concepts In NIDDM on Delivery of Care to Diabetic Populations.- A Paradigm to Link Clinical Research to Clinical Practice: The Challenge in Non-Insulin Dependent Diabetes Mellitus.

Kondo Semiconductors: Kondo Semiconductor CeNiSn (T. Takabatake et al.). Non Fermi-Liquid Ground State in the Heavy Fermion Compounds (F.G. Aliev). 4f and 5f Compounds: Specific Heat of Some Uranium Based Ternary Compounds (T. Fujita et al.). Magnetic Ordering of 122 U and Ce Intermetallic Compounds Described Via an fd Hybridization Model (J.A. Mydosh et al.). Supercoductivity of f electron Systems: Transport and Thermal Properties of Some Selected Heavy Fermion Materials (A. de Visser). Thermal Properties of Heavy Fermion Superconductors (J.P. Brison et al.). Theory: The Ground State of the One Dimensional Kondo Lattice Model (M. Sigrist et al.). Anisotropic Transport Properties of Cerium Kondo Compounds (A.K. Bhattacharjee et al.). Short Presentations: Specific Heat in a Low Carrier Concentration Compound (N. Sato et al.). 23 additional articles. Index.

Stress, the Hypothalamic-Pituitary-Adrenal Axis, and Immune Function; M. Stein, A.H. Miller. Psychological Stress, Immunity and Immune Depression; A. Falek. Opiods, Receptors, and Immunity; M.W. Adler, et al. Consequences of Opiate-Dependency in a Monkey Model of AIDS; R.M. Donahoe, et al. Effects of Opioids on Proliferation of Mature and Immature Immune Cells; H.H Loh, et al. Immune Alterations in Chronic Morphine-Treated Rhesus Monkeys; D.J.J. Carr, C.P. France. Immunosuppressive Effects of Morphine on Immune Responses in Mice; T.K. Eisenstein, et al. MorphineInduced Modulation of Immune Status; D.T. Lysle, et al. Morphine Binding Sites on Human T Lymphocytes; J.J. Madden, et al. Marijuana and Bacterial Infections; T.W. Klein, et al. Effects of Marijuana on Spleen Lymphocytes from Mice of Different Age Groups; S. Pross, et al. Syphilis and Drugs of Abuse; L.J. Paradises, H. Friedman. Marijuana and Host Resistance to Herpesvirus Infection; G.A. Cabral, et al. 24 additional articles. Index.

Plenary Papers.- Systems Science - Addressing Global issues.- Systems Science.- The Actor as a Perfect Citizen.- Information Systems and Systems Science.- Engineering Systems.- Giving Requisite Variety to Strategy and Information Systems.- United Kingdom Higher Education - A Systems Failure?.- Systems Practitioners: Facilitators of the Bringing - Forth of Social Systems.- A Theoretical Framework for an Interpretive-Systemic Study of Public Health Services in Venezuela.- Business Systems.- Metagame Analysis as a Tool for Longitudinal Analysis of Multi-Actorial Decision Processes.- Cultural Contradictions Impeding Global Competitiveness of American High-Technology Firms.- Systems Methodologies and Enabling Technologies: A Role for Group Support Systems?.- The Evaluation of IT Investment.- Heuristic Methods as an Instrument to Develop a Manager.- Suprahuman Systems and Management: Steering in Jeopardy?.- Using an Organisation Wide Consultation Approach for the Creation of Information and Information Technology Strategies.- Complex Systems.- Systems Synthesis.- Mapping Conceptual Models on to the Real World.- Systems Modelling with Natural Language and Fuzzy Logic.- Critical Systems.- Practising Freedom.- Ecology and Evaluation: The Macro-Quality Perspective.- 'Non-Traditional' Logistics - A Step Forward?.- Critical Systems Thinking, Post-Modernism and the Philosophy of Richard Rorty.- Cybernetics.- Nonlinear Dynamics and Fire Risk Assessment.- A Cybernetic View of Quality Management.- Innofusion: Feedback in the Innovation Process.- Organizational Cybernetics.- Moving Management Around the Organisation or How to Make Jobs for the Boys.- Cybernetics & the Social: Conversations with Unspeakable Machines.- Linking SSM with VSM for Information System Management.- Cybernetics in Management.- A Workshop Methodology Based on the "Viable System Model" of Stafford Beer.- Educational Systems.- Reading as a Complex Phenomenon.- Design of Vocational Education Systems: A Systems Science Contribution to the "Competences" Debates.- Designing an MBA Curriculum for Information Systems Managers: An Analysis of Contextual Factors.- Theseus - A Model for Global Connectivity.- Problem-Solving Skills within the Curriculum: A Case for a "Softer" Approach.- Creativity and Science Ecology of Mind: The Future Sight of Science has Begun.- Sport Training as an Open System.- Introducing Systems Thinking into Mathematics Learning.- Systems Education: is There a Mass Delivery Approach?.- Computer-Based Methods of Knowledge Acquisition and Elicitation in Terms of the Subjective Representations and Teaching of Complex Domains.- Developments in the Automation of SSM Tutorials Using Multimedia Technology.- Environmental Systems, Social Systems, and Health Systems.- Systems Science and the Alternatives to the Changes of Soil in Areas of Traditional Agriculture.- A Systems Approach to Environmental Management.- A Systems Approach to Social Innovation.- Automation Technology as a Human Tool for Accomplishing Human Purposes.- Health for All and Community Participation.- Information Systems.- On the Incommensurability of Hard and Soft Systems Approaches to Information Systems Provision.- Knowledge Elicitation: First Step Towards Managing Floating Information in Financial Sectors.- Information Requirements: A Systems and Knowledge Based Approach.- They Shoot Werewolves, Don't They?.- Function-Oriented Data Modelling.- Conceptual Modelling and DBS/KBS Design.- The Algorithmic Nature of Problem Solving.- Syntax and Semantic Analysis of Mission Statements.- Sublimating Methodologies: The Fallacy of' the Right Thing Right'?.- Application-Oriented Tools for Software Development.- How to Deal with Wicked Problems Using a New Type of Information System.- Metaphorical Thinking and Information Systems: The Example of the Mechanistic Metaphor.- Improving the Impact of Systems Thinking on Information Systems Development.- Towards a Multimedia Based New Information Concept.- Tow...

Theory of Ionization and Electron Emission: Theory of Electron Ejection from Matter by Highly Charged Ion Impact; J.H. Macek. Auger Processes at Metallic Surfaces: Auger Processes at Surfaces; A. Niehaus. Kinetic Auger Processes and Shell Effects: Electron Emission from Silicon Induced by Bombardment with Oxygen Ions; E.A. Maydell. Kinetic Electron Emission from Thin Foils: Electron Ejection Induced by Fast Projectiles; G. Schiwietz. Surface Effects in Kinetic Electron Emission: Electron Emission Phenomena in Grazing Collisions of Fast Ions with Surfaces; H. Winter, et al. Spin Polarized Electron Emission: IonInduced Electron Emission from Magnetic and Nonmagnetic Surfaces; C. Rau, et al. Electron Emission and Charging of Insulators: Secondary Electron Emission from Insulators; J. Schou. Ionization Effects in Semiconductors and Insulators: Ionization Tracks; R.E. Johnson. 23 additional articles. Index.

Advances in Superalloys and High Temperature Intermetallics (J.K. Tien et al.). Influence of the Superplastic Metals on the Future of the Metal Forming Industry (G. Torres-Villaseñor). Advanced Aerospace Materials (F.H. Froes et al.). Microalloyed Steels (L. Martínez). Future Ferrous Technologies (H.W. Paxton). Advanced High Temperature Corrosion Sciences (N. Birks et al.). Engineering Materials (V.M. Castaño et al.). Advanced Textile Structural Composites (F.K. Ko). Cracking and Fatigue in FiberReinforced Metal and Ceramic Matrix Composites (A.G. Evans, F.W. Zok). Metallurgy of Permanent Magnet Alloys (L. Rabenberg). Electron Tunneling in Superconductors Ba-K-Bi-O (R. Escudero). Vapor Deposition Processing (S. Purushothaman et al.). Thin Films for Photovoltaic Applications (R. Asomoza et al.). Optical Properties of New Materials (R.G. Barrera). 6 additional articles. Index.

The Lectures: Conjugated Polymers in Layered Hosts; M.G. Kanatzidis, et al. Staging in Intercalated Graphites, Polymers, and Fullerenes; E.J. Mele. Seminars and Communications: Size-Mismatch Melting in Two Dimensions; N. Mousseau, M.F. Thorpe. Tight Binding Molecular Dynamics for Intercalation Chemistry; M. Menon, et al. Local Oscillator Model for Superconducting Fullerenes; Z. Gedik, S. Ciraci. Some Optical Properties of Fullerenes; B. Friedman. Photoluminescence of Solid State Fullerenes; H.J. Byrne, et al. Magnetic Properties of Alkali Metal Intercalated Fullerides; P. Byszewski, et al. Charge Transport and Percolation in Conducting Polymers; J. Voit. Overview on the Chemistry of Intercalation in Graphite of Binary Metallic Alloys; P. Lagrange. Mineralomimetic Inclusion Behavior of Cadmium Cyanide Systems; T. Iwamoto, et al. 36 additional articles. Index.

Background.- Aging, Comorbidity, and Breast Cancer Survival: An Epidemiologic View.- Squamous Cell Cancer of the Cervix, Immune Senescence and HPV: Is Cervical Cancer an Age-Related Neoplasm?.- Genetics and Epigenetics.- Genetic and Molecular Basis for Cellular Senescence.- A Single Gene Change Can Extend Yeast Life Span: The Role of ras in Cellular Senescence.- A Comparison of the Properties of Human P53 Mutant Alleles.- Gene Structure and Expression in Colorectal Cancer.- Influence of Physiological Changes in the Immune Constitutions in Aging and Cancer.- Tumors and Aging: The Influence of Age-Associated Immune Changes upon Tumor Growth and Spread.- T Cell Differentiation and Functional Maturation in Aging Mice.- Molecular Biology of Age-Related Changes in Some Types of Cancer.- I. Breast Cancer.- Cytogenetics and Clinical Correlations in Breast Cancer.- Breast Cancer: Influence of Endocrine Hormones, Growth Factors and Genetic Alterations.- Regulation of Estrogen Receptor Expression in Breast Cancer.- Aging and Development of Ovarian Epithelial Carcinoma: The Relevance of Changes in Ovarian Stromal Androgen Production.- II. Prostate Cancer.- Prostatic Cancer: An Age-Old Problem.- Stromal-Epithelial Paracrine Interactions in the Neoplastic Rat and Human Prostate.- Heparin-Binding Fibroblast Growth Factors and Prostate Cancer.- Molecular Epidemiology and Treatment Modality in Patients of Different Ages with Leukemias.- Age Related Changes in Adults with Acute Leukemia.- Significance of Chromosomal Chances in Patients of Different Age Groups with Acute Leukemia.- Glucocorticoid Receptors in Leukemias, Lymphomas and Myelomas of Young And Old.- Drug Resistance.- General Aspects of Cancer Chemotherapy in the Aged.- Drug Resistance and Cancer.- Summation and Synthesis.- From the Cancer Cell Biology Point of View.- From the Immunology Point of View.- From the Aging Point of View.- Participants and Contributors.

General Introduction: Dendritic cells: Antigen presentation, accessory function and clinical relevance.- Endocytic activity of dendritic cells is similar to other antigen presenting cells.- Immunocytochemical characterization of dendritic cells.- Requirements of exogenous protein antigens for presentation to CD4+ T lymphocytes by MHC Class II-positive APC.- Modulation of MHC Class II determinants on rat Langerhans cells during short term culture.- A dendritic cell specific determinant present in endosomes is involved in the presentation of protein antigens.- Dendritic cells are potent antigen-presenting cells for microbial superantigen.- Divergent T-cell cytokine profiles induced by dendritic cells from different tissues.- Adhesion molecules: Co-stimulators and Co-mitogens in dendritic cell - T cell interaction.- Dendritic cell dependent expression of IgA by clones in T/B microcultures.- Adhesion molecules in tonsil DC-T cell interactions.- Dendritic cells have reduced cell surface membrane glycoproteins including CD43 determinants.- The effect of human dendritic cells on the lectin-induced responsiveness of CD4+ T cells to IL-2 and IL-4.- Analysis of cytokine and cytokine receptor production by human dendritic cells.- Costimulating factors and signals relevant for antigen presenting cell function.- Distinct T cell stimulation mechanism and phenotype of human blood dendritic cells.- The role of dendritic cells in the regulation of T cell cytokine synthesis.- The role of dendritic cells as co-stimulators in tolerance induction.- The influence of dendritic cells on T-cell cytokine production.- Phenotypical and functional characterization of dendritic cells in the human peritoneal cavity.- Dendritic cells isolated from rat and human non-lymphoid tissue are very potent accessory cells.- Antigen presenting capacity of peritoneal macrophages and dendritic cells.- T-cell repertoire development in MHC class II deficient humans.- Rat thymic dendritic cells.- Rat thymic dendriticCells: flow cytometry analysis.- Ultrastructure of interdigitating cells in the rat thymus during Cyclosporin A treatment.- T cell tolerance and antigen presenting cell function in the thymus.- Tolerizing mice to human leukocytes: A step toward the production of monoclonal antibodies specific for human dendritic cells.- Morphological and functional differences between HLA-Dr+ peripheral blood dendritic cells and HLA Dr+ IFN-alpha producing cells.- Three monoclonal antibodies to antigen presenting cells in the rat with differential influence on cellular interactions.- The MHC expression of dendritic cells from mouse spleen isolated by centrifugal elutriation is unregulated during short term culture.- II-6 and its high affinity receptor during differentiation of monocytes into Langerhans cells.- Phagocytosis of antigens by Langerhans cells.- Dissection of human Langerhans cell allostimulatory function. Modulation by interferon-?.- Human in vitro T cell sensitization using hapten-modified epidermal Langerhans cells.- Monocyte-derived Langerhans cells from different species - morphological and functional characterization.- A serial section study of mice Langerhans cell granules after DNFB painting.- Skin dendritic cell-lymphocyte interactions in autologous system.- Induction of the low affinity receptor for IgE (Fc?RII/CD23) on human blood dendritic cells by interleukin-4.- Fc? RI mediates IGE-binding to human epidermal Langerhans cells.- Murine epidermal Langerhans cells as a model to study tissue dendritic cells.- Differentiation of dendritic cells in cultures of rat and mouse bone marrow cells.- TNF and GM-CSF dependent growth of an early progenitor of dendritic Langerhans cells in human bone marrow.- Human bone marrow contains potent stimulatory cells for the allogeneic MLR with the phenotype of dendritic cells.- Recombinant GM-CSF induces in vitro differentiation of dendritic cells from mouse bone marrow.- Signals required for differentiating dendritic cells...

An Overview of Developments in Research on Recovery from Brain Injury.- Recovery of Function: Nutritional Factor.- Neural Transplantation and Recovery of Function: Animal Studies.- Neural Implants and Recovery of Function: Human Work.- Environmental Approaches to Recovery of Function from Brain Damage: A Review of Animal Studies (1981 to 1991).- Neuropsychological Rehabilitation.- Hemidecortication and Recovery of Function: Animal Studies.- A Review of Cognitive Outcome after Hemidecortication in Humans.- Compensatory Mechanisms - Neural and Behavioral: Evidence from Prenatal Damage to the Forebrain Commissures.- Mechanisms Underlying Recovery from Cortical Injury: Reflections on Progress and Directions for the Future.- Research on Recovery: Ends and Means.- Author Index.

Methods and Procedures for Preparing Resealed Erythrocytes: IHP Entrapment into Human Erythrocytes; A. Mosca, et al. Resealed Erythrocytes as a Tool for Basic Studies: ATP Monitoring in Human Red Blood Cells with Luciferase Introduced Intracellularly; V.M. Vitvitsky, et al. Resealed Erythrocytes as a Cellular Bioreactors: Acetaldehayde Oxidation by Aldehyde Dehydrogenase Loaded Erythrocytes; P. Ninfali, et al. Resealed Erythrocytes as Advanced Drug Delivery Systems: Erythrocytes as Carriers of New Anti-Opioid Prodrugs; S. Noel-Hocquet, et al. Site Specific Targeting of Resealed Erythrocytes: Erythrocytes as Carriers of Ricin A Chain; N. Chestier, et al. Human and Veterinary Studies Using Resealed Erythrocytes: Susceptibility of Carrier Erythrocytes to a Natural Hemolytic System; H.J. Kirch, et al. 36 additional articles. Index.

Introductory Address.- The New Biology and Vaccine Research.- Keynote Presentation.- Mucosal Immunity To Vaccines: Current Concepts for Vaccine Development and Immune Response Analysis.- Session I: Oral Diseases and Host Immune Responses.- Prospects for Human Mucosal Vaccines.- Bacterial Diseases of the Oral Tissues.- Oral Virus Infections: The Potential for Gene Transfer in Treatment and Prevention.- Session II: Update on Vaccines and Vaccine Development.- Bacterial Mucosal Vaccines.- A General Overview of Viral Vaccine Development.- Session III: Vaccines and the Mucosal Immune System.- An Update on the "Jennerian" and Modified "Jennerian" Approach to Vaccination of Infants and Young Children Against Rota Virus Diarrhea.- Induction of Mucosal and Serum Immune Responses to a Specific Antigen of Peridontal Bacteria.- IgA1 Proteases and Host-Parasite Relationships in the Oral Cavity.- Transport of Iga Immune Complexes Across Epithelial Membranes: New Concepts n Mucosal Immunity.- Effect of Mucosal Microenvironment on Immune Response to Viruses.- Session IV: Optimizing Mucosal and Systemic Immune Responses.- Induction of T Helper Cells and Cytokines For Mucosal IgA Responses.- Cytokine Production and T Cell Receptor Expression by Salivary Gland T Cell and Intraepithelial T Lymphocytes for the Regulation of the IgA Response.- Immunological Adjuvants.- Session V: Delivery Systems and Immune Analysis.- M Cell-Mediated Antigen Transport and Monoclonal IgA Antibodies For MucosalImmune Protection.- A Mechanism of Passive Immunization with Monoclonal Antibodies to a 185,000Mr Streptococcal Antigen.- Delivery of Antigens by Recombinant Avirulent Salmonella Strains.- Use of Recombinant BCG as a Vaccine Delivery Vehicle.- Vaccinia Virus Recombinants as Potential Herpes Simplex Virus Vaccines.- Liposomes and Conjugate Vaccines for Antigen Delivery and Induction of Mucosal Immune Responses.- Peroral Immunization with a Cholera Toxin-Linked Bacterial Protein Antigen and Synthetic Peptide.- Peptomers as Vaccine Candidates.- Session VI: Target Antigen Selection and Vaccine Development.- Structural and Functional Studies of Herpes Simplex Virus Glycoprotein D.- Molecular, Immunological and Functional Characterization of the Major Surfae Adhesin of Streptococcus Mutans.- Reacitve Antigens of the Periodontopathic Bacterium Actinobacillus Actinmycetemcomitans.- Immunization with Fimbrial Protein and Peptide Protects Against Porphyromonas Gingivalis- Induced Periodontal Tissue Destruction.- Vaccine Development: Progression from Target Antigen to Product.- Session VII: Immunological Correlates of Protection.- Significance of Immune Responses to Oral Antigens in Dental Diseases.- Laboratory Correlates of Protection and Protective Immunity to Bordetella Pertussis.- Future Directions.- Challenges and Opportunities in Vaccine Research.- Summary and Recommendations for Future Research.- Speakers and Moderators.- Author Index.

Modern Power Devices: Technology for High Power Devices (T. Ohmi). The MosControlled Thyristor and its Limits (F. Bauer). High Power Reverse Conducting GTO (P. Streit). Review of Power Device Concepts (R. Sittig). Simulation: Tool Integration for Power Device Modeling Including 3D Aspects (R.W. Dutton, J.D. Plummer). Use of CAD Tools in Power Device Optimization (W. Fichter et al.). Modeling the Limit of Stable Device Behavior (K. Lilja). Circuits and Control Concepts: Comparative Study of High Power Devices in Converter Circuits (H.Ch. Skudelny et al.). HVDC Valves with Light Triggered Thyristors (B.E. Danielsson). Intelligent Power Integrated Circuits (J.M. Peter). Future Trends: New Circuit Topologies (T.A. Lipo, D.M. Divan). Advanced Power Modules for Drives and Automation (H.J. Krokoszinsky, S. Kjellnäs). Power Electronics in Electrical Power Transmission Systems (A. Ekström). New Materials Beyond Silcon (B.J. Baliga). Index.

Modeling of Oxygen Transport to Skeletal Muscle: Blood Flow Distribution, Shunt, and Diffusion.- The Haldane Effect of Rabbit Blood Under Different Acid-Base Conditions.- Interaction of Blood Flow, Diffusive Transport and Cell Metabolism in Isovolemic Anemia.- The Role of Wall Shear Stress in Microvascular Network Adaptation.- Changes in Tissue Histology Associated with Adaptation and Acclimation to Hypoxia.- Transcutaneous Measurements of Skin O2 Supply and Blood Gases.- Relating Measuring Signals from PO2 Electrodes to Tissue PO2: A Theoretical Study.- A New Catheter for Quasi-Continuous Measurement of Arterial Partial Oxygen Pressure.- Continuous Intra-Arterial PO2 Monitoring During Thoracic Surgery.- Construction, Calibration and Evaluation of PO2 Electrodes for Chronical Implantation in the Rabbit Brain Cortex.- Photothrombosis in Rabbit Brain Cortex: Follow Up by Continuous pO2 Measurement.- Intravitreal and Intraretinal Oxygen Tension in the Rat Eye.- Brain Oxygenation State: Preparation of Isolated Perfused Rat Brain and Near-Infrared Spectrophotometry.- The Simultaneous Measurement of the Redox State of Cytochrome Oxidase in Heart and Brain of Rat In Vivo by NIR.- Picosecond Time of Flight Measurement of Living Tissue: Time Resolved Beer-Lambert Law.- Cerebral Oxygenation State in Chemically-Induced Seizures in the Rat: Study by Near Infrared Spectrophotometry.- Experimentally Measured Optical Pathlengths for the Adult Head, Calf and Forearm and the Head of the Newborn Infant as a Function of Inter Optode Spacing.- Near-Infrared Imaging in vivo (I): Image Restoration Technique Applicable to the NIR Projection Images.- Muscle Oxygenation by Fast Near Infrared Spectrophotometry (NIRS) in Ischemic Forearm.- Near-Infrared Imaging in vivo (II): 2-Dimensional Visualization of Tissue Oxygenation State.- Monitoring of the Oxygen Pressure in the Blood of Live Animals Using the Oxygen Dependent Quenching of Phosphorescence.- Nuclear Magnetic Resonance Spectroscopy and the Study of Tissue Oxygen Metabolism: A Review.- On-Line Oxygen Uptake Measurement (VO2): A Computer Feed-Back Controlled Rebreathing Circuit for Long Term Oxygen Uptake Registration.- Oxygen Delivery (DEL O2) Dependent and Independent Oxygen Consumption (VO2).- Microtopographic Analysis of Oxidative Stress in Organ Microcirculatory Units.- Cytochrome P-450 Under Conditions of Oxidative Stress: Role of Antioxidant Recycling in the Protection Mechanisms.- Ischemia-Reperfusion Injury and Free Radical Involvement in Gastric Mucosal Disorders.- Influence of Anti-Inflammatory Drugs and Free Radical Scavengers on Intestinal Ischemia Induced Oxidative Tissue Damage.- Influence of Free Radical Scavengers on Myeloperoxidase Activity and Lipid Peroxidation in Acute Skin Grafts.- Morphometric Methods for the Evaluation of Capillary Grouping Patterns in Rat Heart.- Estimation of the Oxygen Gradient Across Phospholipid Bilayers of Mitochondria from Reperfused Rabbit Hearts after Ischemia.- The Oxygen Dependence of Mitochondrial Oxidative Phosphorylation and Its Role in Regulation of Coronary Blood Flow.- Oxygen Penetration in and Release from Lung Surfactant.- Improvement of Pulmonary Gas Exchange After Surfactant Replacement in Rats With Pneumocystis Carinii Pneumonia.- Attenuation of Hypoxic Pulmonary Vasoconstriction in Acute Oleic Acid Lung Injury: Significance of Vasodilator Prostanoids.- 99mTc-DTPA Clearance: A Sensitive Method for Early Detection of An Impending Disturbance in Gas Exchange.- Acute Respiratory Failure During Pneumonia Induced by Sendai Virus.- Estimation of Respiratory Mechanics in Dogs with Acute Lung Injury.- Effect of Hyperventilation on Oxygenation of the Brain Cortex of Neonates.- Hypoxia and the "Reaction Theory" of Central Respiratory Chemosensitivity.- Oxygenation of Mammary Tumors: From Isotransplanted Rodent Tumors to Primary Malignancies in Patients.- Measurements of Tumor Blood Flow Using Intraperitoneal Deuterium and 2H-NMR Spectroscopy....

Part A: Heat and Mass Transfer in Helium II: A Brief History of Cryogenics; R.G. Scurlock. Applications of Helium II: A Liquid/Gas Phase Separator for HeI and HeII; P.J. Shirron, et al. Heat Transfer in Cryogenc Fluids; Heat Exchangers; Thermoacoustic Oscillations. Insulation. Applications of Superconductivity: Magnet Stability; Coil Protection. Applications of Superconductivity: Magnets and Other Devices. Applications of Superconductivity: Cryogenic Techniques. Refrigeration for Electronics. Refrigeration of Superconducting Systems. Part B: Compressors, Expanders, Pumps for Liquid Helium. Magnetic Refrigerators. Pulse Tube Refrigerators. Cryocoolers. Properties of Cryogenic Fluids. Cryogenic Applications: Transportation. Cryogenic Applications: Space Science and Technology. Cryogenic Applications: Equipment for Space. Cryogenic Instrumentation. Miscellaneous Cryogenic Techniques and Applications. 170 additional articles. Index.

A Perspective of Resonant Tunneling; L.L. Chang. Materials and Band-Structure Effects: Epitaxial Growth of Atomically Smooth GaAs/AlxGa1xAs Interfaces for Resonant Tunneling; K. Ploog. MBE Growth of High Performance GaAs/GaAlAs and InGaAs/GaAlAs Double Barrier Quantum Well Structures for Resonant Tunneling Devices; H. Riechert, et al. Tunneling in Polytype InAs-AlSb-GaSb Heterostructures; K.F. Longenbach, et al. Scattering and Dynamic Effects: Scattering processes, Coherent and Incoherent Transport in Resonant Tunneling Structures; B. Vinter, et al. Quantum Coherence and Phase Randomization in Series Resistors; M. Büttiker. Charge Buildup, Intrinsic Bistability and Energy Relaxation in Resoant Tunneling Structures: High Pressure and Magnetic Field Studies; L. Eaves, et al. Multiple-Barrier and Low-Dimensional Systems: Miniband Transport and Resonant Tunneling in Superlattices; J.F. Palmier. Transport in Superlattices: Observation of Negative Differential Conductance by Field Induced Localization and Its Equivalence with the Esaki-Tsu Mechanism: Scattering Controlled Resonances in Superlattices; F. Capasso, et al. Device Structures: High-Frequency Oscillators Based on Resonant Tunneling; T.C.L.G> Sollner, et al. 39 additional articles. Index.

Development of the Primate Visual System throughout Life; P. Rakic. Animal Modes of LifeSpan Development; W. Hodos. Ontogenetic Clues to the Phylogeny of the Visual System; B. Fritzsch. Aging and Spatial Contrast Sensitivity; C. Owsley. Synaptic Plasticity in the Adult Vertebrate Retina; M.B.A. Djamgoz. Development of the Visual Cortex Deprived of Retinal Cues; R.O. Kuljis. Cellular and Molecular Aspects of Neuronal Differentiation; G. Augusti-Tocco, et al. Visual System in Some Somatic Diseases; F.F. Demircioglu. Effects of Intraocular Activity Blockade on the Morphology of Developing LGN Neurons in the Cat; K. Herrmann. A Neural Network Model for Stripe Formation in Primate Visual Cortex; W. Cowan, M.J. Zuckerman. Stereo Matching Using Relaxation Labeling Based on Edge and Orientation Features; J.S. Jin. Twentyfour additional articles. Index.

Architecture and Hardware Support for AI Processing: VLSI Design of a 3D Highly Parallel MessagePassing Architecture (J.L. Bechennec et al.). Architectural Design of the Rewrite Rule Machine Ensemble (H. Aida et al.). A Dataflow Architecture for AI (J. DelgadoFrias et al.). Machines for Prolog: An Extended Prolog Instruction Set for RISC Processors (A. Krall). A VLSI Engine for Structured Logic Programming (P. Civera et al.). Performance Evaluation of a VLSI Associative Unifier in a WAM Based Environment (P. Civera et al.). Analogue and Pulse Stream Neural Networks: Computational Capabilities of BiologicallyRealistic Analog Processing Elements (C. Fields et al.). Analog VLSI Models of Mean Field Networks (C. Schneider et al.). An Analogue Neuron Suitable for a Data Frame Architecture (W.A.J. Waller et al.). Digital Implementations of Neural Networks: The VLSI Implementation of the sigma Architecture (S.R. Williams et al.). A Cascadable VLSI Architecture for the Realization of Large Binary Associative Networks (W. Poechmueller et al.). Digital VLSI Implementations of an Associative memory Based on Neural Networks (U. Rückert). Arrays for Neural Networks: A Highly Parallel Digital Architecture for Neural Network Emulation (D. Hammerstrom). 26 additional articles. Index.