Bøker utgitt av Springer Nature Singapore

This book focuses on the cohering elements across various texts and traditions of India. It engages with several significant works from the Sanskrit tradition and emphasizes the need to move beyond colonial and postcolonial engagements with the enduring cultural pasts of India. The chapters are grouped in three main parts: accented rhythms, dispersed mnemoscapes and inventive iterations. It addresses questions such as: what enabled cultural communication across very divergent geographical, temporal, locational contexts and among different cultural formations of India over millennia? What is this shareable impulse that pulsates across the domains of dance, sculpture, painting, poetry, dharma, music, medicine, the lore of rivers and the epics?  It explains how modern Indian languages and especially their creative and reflective nodes are unthinkable without the intricately woven textures of these interfaces and their responsive receptions. This book is of interest to philosophers, humanities students, researchers and professors as well as people interested in exploring alternatives to European traditions of thought without an alibi.  

This book, now in a thoroughly revised and updated second edition, provides the latest information on cancer metastasis from the perspective of inflammation and presents new ideas on the complicated mechanisms of metastasis and potential therapeutic targets. Key features include discussion of mechanisms recently identified to be involved in the resolution phase of inflammation, presentation of the latest evidence regarding the roles of endogenous TLR4 ligands in metastasis, and thorough explanation of the concept of homeostatic inflammation and current understanding of the significance of its dysregulation for metastasis. Structure-based thinking is another important element of the book, and it is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, at the center of which cancer is located. Examples of the many additional specific topics covered in this edition include the functional involvement of new types of RNA in cancer, the insights offered by recent advances in bioinformatics, and the potential of a casein kinase 1a inhibitor in the treatment of acute myeloid leukemia. The book will be a valuable update and resource for both experienced and younger researchers.Homeostasis, originated from an idea of internal milieu by Claude Bernard, is eventually maintained by endogenous elements. The essential features of inflammation are leukocyte mobilization and increased vascular permeability, which could take place in many homeostatic or physiological conditions at low levels. Homeostatic inflammation is a concept to explain pathological settings such as metastasis in which irrespective of its level those inflammatory features are misused with endogenous molecules (see Chap. 14,15).As inflammation comprises many biological fields, targeting a single molecule for a disease could potentially make a therapeutic contribution to other diseases. For example, one focus is applied here to the roles of calprotectin in lung metastasis, which is implicated in psychiatric disorders and COVID-19 as shown by recent evidence.

This book provides readers with a comprehensive overview of cold plasma technology for tackling the various food-related hazards in a wide range of food sectors. The principles and characteristics of cold plasma generation in gas and its interaction with liquids, as well as its combating modes of action for common hazards (e.g., bacteria, spores, biofilms, fungi, and fungal toxins) are emphasized in this book. It also presents the applications of cold plasma or its hurdles with other techniques to assure the microbiological safety of the key food classifications, including fruits, vegetables, cereals, grains, meat, aquatic products, liquid food products (e.g., juices, milk), nuts, spices, herbs, and food packaging.This book is useful for researchers to grasp the comprehensive understandings of how food safety can be controlled with cold plasma technology. This book also provides adequate information for engineers in food industry for better development and optimization of the plasma-generating systems. Government institutions that are responsible for food safety regulations can understand more knowledge about the intricacies and influencing factors, which should be considered for regulating the applications of cold plasma technology in food.

This Atlas covers various types of lip and nose deformities and introduces individualized surgical plan for patients. The surgical techniques are classified according to the various types of deformities. Schematic diagrams, pre-operative and post-operative photographs are supplemented by detailed explanations. It consists of four parts: anatomical structure of lips and nose; cosmetic surgery of lips and nose; plastic surgery of nasolabial congenital deformity; plastic surgery of acquired nasolabial defect and deformities.The management of nasolabial deformities and defects crosses many surgical disciplines, and therefore, this book recommended to be read by surgeons of different backgrounds i.e. oral and maxillofacial surgery, plastic surgery, cosmetic surgery, otorhinolaryngology, etc. It can also be used as a reference for anatomy, developmental biology, physiology, linguistics, aesthetics and other basic medical sciences. 

This book introduces the principles and mechanisms of the biological synthesis of nanoparticles from microorganisms, including bacteria, fungi, viruses, algae, and protozoans. It presents optimization processes for synthesis of microbes-mediated nanoparticles. The book also reviews the industrial and agricultural applications of microbially-synthesized nanoparticles. It also presents the medical applications of green nanoparticles, such as treating multidrug-resistant pathogens and cancer treatment. Further, it examines the advantages and prospects for the synthesis of nanoparticles by microorganisms. Lastly, it also presents the utilization of microbial-synthesized nanoparticles in the bioremediation of heavy metals.

This journal-like book series includes edited volumes to rapidly report and spread the latest technological results, new scientific discovery and valuable applied researches in the fields concerning offshore robotics as well as promote international academic exchange. We aim to make it one of the premier comprehensive academic publications of world offshore vehicle and robotics community.The audience of the series will include the scholars, researchers, engineers and students who are interested in fields of autonomous marine vehicles and robotics, including autonomous surface vehicles, autonomous underwater vehicles, remote operation vehicles, marine bionics, marine vehicle modeling, guidance, navigation, control and cooperation and so on.

This volume is the most comprehensive and up-to-date compilation of in-depth analyses on human rights violations committed in war. It offers myriad perspectives on the content and application of legal protections offered to civilians, including women, children and the elderly, and to others who are 'no longer active in the fight.' A series of carefully researched case studies illustrates the extent to which human rights violations occur in recent and current armed conflict, and signals the ways in which these violations are dealt with. Each of the contributing authors has been selected on the basis of their international academic reputation and/or professional standing within the human rights field. Given the alarming numbers of people harmed in recent and current armed conflict, this book will be of great interest to researchers, policymakers and opinion-shapers alike.

The book is presenting a comprehensive information on fundamental, and applied knowledge of Plasmodiophora brassicae Woronin. infecting cruciferous crops, and weeds. Clubroot of crucifers has spread over more than 88 countries of the world with average annual loss of cruciferous crops from 10-15 per cent at global level. It is considered as a disease of cultivation since once introduced in a field, its inoculum piles up year by year in the form of resilient resting spores of P. brassicae which spreads in the field through field operations.  This disease is very unique since the pathogen can survive in the soil in the rhizosphere of non-host plants in addition to its main host cruciferous species, cultivated or wild.  This book complies inclusive information about the disease, its geographical distribution, symptoms, host range, yield losses, and disease assessment scales. The book also explores host-parasite interactions in the form of seed infection, disease cycle, process of infection, pathogenesis, epidemiology and forecasting. Chapters discuss the genetic and molecular mechanisms of host-parasite relationships, management practices including cultural, chemical, biological control practices, and other integrated approaches. The book is immensely useful to researchers, teachers, extension specialists, farmers, and all others who are interested to grow healthy and profitable cruciferous crops all over the world. Also the book serves as additional reading material for undergraduate and graduate students of agriculture and especially plant pathology. National and international agricultural scientists, policy makers will also find this to be a useful read.

This book introduces "e;network pharmacology"e; as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used.In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "e;network target"e; for the first time, which has become the core theory of "e;network pharmacology"e;. The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied.This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.

This book provides insight into the underlying basic theories and concepts in X-ray, light, and neutron scattering. The three scattering principles are systematically presented, together with a unified description based on elastic scattering of electromagnetic waves and the Schrodinger wave from matter. These explanations are presented with an introduction of their common Born approximation using a consistent set of symbols and terminology and with step-by-step derivations of equations.  This book emphasizes the combined applications of these three scattering methods, wherever and whenever possible, as a very powerful methodology for characterization of internal structures of soft matters in the length scale ranging from subnanometers to a few 10 micron meters. These applications include explorations for evolution of hierarchically self-organized internal structures of a variety of soft matters, including cells, under diverse environmental conditions.This book will not only be an excellent resource for graduate students and academic researchers who analyze structures of soft matters and polymers, but it will also be useful for researchers in industries.

This book gathers the proceedings of the 9th International Symposium on Coal Combustion, held in Qingdao, China in July 2019. It provides the latest research results on techniques for pulverized coal combustion and fluidized bed combustion, low-carbon energy and emission controls, and industrial applications. Highlighting research areas that are of great importance in promoting collaboration between related subjects and the technical development of coal-related fields, the book offers a valuable reference guide for researchers and engineers alike. 

This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy.

The book highlights various pediatric cataract surgeries. It covers variants of pediatric cataract along with other rare morphologies. It covers selected challenging clinical situations along with surgical management steps. Additionally, it includes the management of surgical complications. The book provides relevant concise text supported by clinical pictures and includes 50 short videos. This book is a collection of clinical images and videos over 2 decades. Chapters cover recent advances in the field of pediatric cataract, such as ultrasound biomicroscopy, intraoperative rhexis assistant, operative room aberrometry. The accompanying video describes the surgical procedures with a voiceover lucidly explaining every step. It discusses unique cases of buphthalmous with cataract, anterior segment dysgenesis, persistent fetal vasculature and pre-existing persistent capsular defect with their latest management techniques.This book is relevant for practicing ophthalmologists and students alike.

This book presents high-quality papers from the Fifth International Conference on Microelectronics, Computing & Communication Systems (MCCS 2020). It discusses the latest technological trends and advances in MEMS and nanoelectronics, wireless communication, optical communication, instrumentation, signal processing, image processing, bioengineering, green energy, hybrid vehicles, environmental science, weather forecasting, cloud computing, renewable energy, RFID, CMOS sensors, actuators, transducers, telemetry systems, embedded systems and sensor network applications. It includes papers based on original theoretical, practical and experimental simulations, development, applications, measurements and testing. The applications and solutions discussed here provide excellent reference material for future product development.

This book covers various current and emerging topics in construction management and real estate. Papers selected in this book cover a wide variety of topics such as new-type urbanization, planning and construction of smart city and eco-city, urban-rural infrastructure development, land use and development, housing market and housing policy, new theory and practice of construction project management, big data application, smart construction and BIM, international construction (i.e., belt and road project), green building, off-site prefabrication, rural rejuvenation and eco-civilization and other topics related to construction management and real estate. These papers provide useful references to both scholars and practitioners. This book is the documentation of "e;The 24th International Symposium on Advancement of Construction Management and Real Estate,"e; which was held in Chongqing, China.

This comprehensive, up-to-date reference work compiles the scientific research on the relationship between various forms of cancer and reactive oxygen species (ROS). It is well known that ROS play a key role in the various steps leading to malignancy, this includes increase in DNA mutation rates. The book brings together exciting reviews, written by leading experts all over the world.The book is divided into four broad sections. Each section describes the role of oxidative stress and underlying mechanisms and pathways, at various stages of cancer, including its role in carcinogenesis, cancer progression and metastasis. Further, the book describes how the reactive oxygen species (ROS) modulate gene expression and signal transduction pathways in cancer. The book discusses the ways to interfere with the cancer progression, and design of anti-cancer drugs. The book provides an integrated approach for better understanding of the development phases of oxidative stress-induced cancers, and mainly the current perspectives about mechanistic aspects of cancer initiation, progression and metastasis.It is a highly resourceful book and would be extremely important to clinicians, students and researchers in the field of cancer genetics, therapeutics and oncology.

This book contains an up-to-date survey and self-contained chapters on complex slant submanifolds and geometry, authored by internationally renowned researchers. The book discusses a wide range of topics, including slant surfaces, slant submersions, nearly Kaehler, locally conformal Kaehler, and quaternion Kaehler manifolds. It provides several classification results of minimal slant surfaces, quasi-minimal slant surfaces, slant surfaces with parallel mean curvature vector, pseudo-umbilical slant surfaces, and biharmonic and quasi biharmonic slant surfaces in Lorentzian complex space forms. Furthermore, this book includes new results on slant submanifolds of para-Hermitian manifolds. This book also includes recent results on slant lightlike submanifolds of indefinite Hermitian manifolds, which are of extensive use in general theory of relativity and potential applications in radiation and electromagnetic fields. Various open problems and conjectures on slant surfaces in complex space forms are also included in the book. It presents detailed information on the most recent advances in the area, making it valuable for scientists, educators and graduate students.

The idea of structure-preserving algorithms appeared in the 1980's. The new paradigm brought many innovative changes. The new paradigm wanted to identify the long-time behaviour of the solutions or the existence of conservation laws or some other qualitative feature of the dynamics. Another area that has kept growing in importance within Geometric Numerical Integration is the study of highly-oscillatory problems: problems where the solutions are periodic or quasiperiodic and have to be studied in time intervals that include an extremely large number of periods. As is known, these equations cannot be solved efficiently using conventional methods. A further study of novel geometric integrators has become increasingly important in recent years. The objective of this monograph is to explore further geometric integrators for highly oscillatory problems that can be formulated as systems of ordinary and partial differential equations.Facing challenging scientific computational problems, this book presents some new perspectives of the subject matter based on theoretical derivations and mathematical analysis, and provides high-performance numerical simulations. In order to show the long-time numerical behaviour of the simulation, all the integrators presented in this monograph have been tested and verified on highly oscillatory systems from a wide range of applications in the field of science and engineering. They are more efficient than existing schemes in the literature for differential equations that have highly oscillatory solutions. This book is useful to researchers, teachers, students and engineers who are interested in Geometric Integrators and their long-time behaviour analysis for differential equations with highly oscillatory solutions. 

The book examines the role of artificial intelligence during the COVID-19 pandemic, including its application in i) early warnings and alerts, ii) tracking and prediction, iii) data dashboards, iv) diagnosis and prognosis, v) treatments, and cures, and vi) social control. It explores the use of artificial intelligence in the context of population screening and assessing infection risks, and presents mathematical models for epidemic prediction of COVID-19. Furthermore, the book discusses artificial intelligence-mediated diagnosis, and how machine learning can help in the development of drugs to treat the disease. Lastly, it analyzes various artificial intelligence-based models to improve the critical care of COVID-19 patients.

This book presents select papers from the International Conference on Energy, Material Sciences and Mechanical Engineering (EMSME) - 2020. The book covers the three core areas of energy, material sciences and mechanical engineering.  The topics covered include non-conventional energy resources, energy harvesting, polymers, composites, 2D materials, systems engineering, materials engineering, micro-machining, renewable energy, industrial engineering and additive manufacturing. This book will be useful to researchers and professionals working in the areas of mechanical and industrial engineering, materials applications, and energy technology.

This book presents state of the art knowledge on new techniques and materials that can improve functional and aesthetic results in wound healing while reducing invasiveness, based on the author's extensive personal experience. The aim is to equip the practitioner with all the information required in order to select a strategy that will accelerate wound healing and minimize both the risk of complications and scar formation after the wound has fully healed. The opening chapters set the stage by providing an overview of wound healing, including brief descriptions of the anatomy of the skin, the wound healing process, and advanced wound dressings. A full description follows of the various methodologies employed in repairing acute wounds with the goal of achieving optimal functional and cosmetic outcomes while utilizing the safest and least invasive method. Treatment protocols that have proven successful in closing nonhealing and/or delayed healing chronic wounds are then presented. In addition, a chapter addresses aesthetic procedures using advanced technology in wound healing. The closing chapter presents author¿s experience with the establishment a hospital wound dressing team. The text is complemented by a comprehensive collection of full-color photos. Since the publication of the second edition, there have been many notable advances in wound healing research. The third edition is expanded and updated to reflect the advancements and new information. Key revisions include new chapters and/or sections on recently developed dressings such as a bioelectric dressing, a fluorescence imaging device of bacteria, usefulness of fibrin glue to support wound healing, graft of 3D-printed micronized adipose tissue, significance of skin hydration level for wound healing, novel staged excision technique to reduce scar length, newly developed risk scoring system to predict wound healing outcomes in diabetic patients, expanded coverage of cell therapy, new devices such as extracorporeal shock wave therapy, and automated SVF cell isolation system.

This book presents a new organizing framework for studying democratic recession and autocratization in Southeast Asia. By introducing a new concept, ¿democratic backlash,¿ the book details how democratic recession inevitably provokes resistance that often forms the nucleus of new democratic movements, and in doing so, argues that it is important to identify these reverse trends that may eventually become dominant.The book contributes to current literature which thus far has sought to understand the causes and consequences of the decline in democracy around the world. Previous literature has focused primarily on advanced democracies, or alternatively, on large scale quantitative comparison. As such, this book helps fill a research gap with its focus on Southeast Asia, employing a comparative case study approach.Chapter authors are experts on Southeast Asia, a region that has experienced democratic recession and autocratization in a variety of ways, from rising populism to military coups.

The book provides various EdgeAI concepts related to its architecture, key performance indicators, and enabling technologies after introducing algorithmic government, large-scale decision-making, and computing issues in the cloud and fog. With advancements in technology, artificial intelligence has permeated our personal lives and the fields of economy, socio-culture, and politics. The integration of artificial intelligence (AI) into decision-making for public services is changing how governments operate worldwide. This book discusses how algorithms help the government in various ways, including virtual assistants for busy civil servants, automated public services, and algorithmic decision-making processes. In such cases, the implementation of algorithms will occur on a massive scale and possibly affect the lives of entire communities. The cloud-centric architecture of artificial intelligence brings out challenges of latency, overhead communication, and significant privacy risks. Due to the sheer volume of data generated by IoT devices, the data analysis must be performed at the forefront of the network. This introduces the need for edge computing in algorithmic government. EdgeAI, the confluence of edge computing and AI, is the primary focus of this book. It also discusses how one can incorporate these concepts in algorithmic government through conceptual framework and decision points. Finally, the research work emphasizes some design challenges in edge computing from applications viewpoint. This book will be helpful for data engineers, data scientists, cloud engineers, data management experts, public policymakers, administrators, research scholars and academicians.

This book traces the development of U.S-led global nuclear non-proliferation diplomacy during the three decades since the Eisenhower¿s ¿Atoms for Peace¿ in 1953. The U.S. non-proliferation efforts had diverse obstacles. It had to prevent nuclear states¿ export of nuclear technology while dissuading non-nuclear states from developing nuclear weapons. In addition, building non-proliferation regime was not always its top foreign policy priority. To understand the complex process of non-proliferation, the book examines the relations among three different actors in the nuclear field: a global non-proliferation regime builder (U.S.), a potential nuclear proliferator (France) and a would-be nuclear state (Republic of Korea). In tracing how they developed nuclear strategies, conflicting and compromising with one another, the book pays special attention to how the transforming Cold War structure in the 1970s not only affected foreign policies of the involved countries but also complicated theirrelationship. The exploration ultimately highlights the multidimensional nature of international discussion on nuclear non-proliferation as the ROK¿s nuclear development attempts, U.S. non-proliferation efforts, and the U.S.-France nuclear technology cooperation in the 1970s were all deeply connected.

This book explores the contextual, particularly cultural-related, factors that may impact reading outcomes of young Indigenous learners in their early years, underpinned by the conceptual framework of cultural capital originated by Bourdieu. By drawing upon a participatory and exploratory case study, conducted at a regional school in Australia over a period of six months, it highlights the challenges that Indigenous students face in reading, and how the contextual factors contribute to Indigenous students¿ development in reading skills and their reading performance. This book helps readers to gain a better and deeper understanding of Indigenous culture, the importance of the role that culture plays in Indigenous children¿s literacy education, and how it shapes the way they learn and think.

This edited book focuses on ROS synthesis, potential applications, toxicity, and preservations. It explores the recently proposed hormonal response and biomolecules targeted in regulation of ROS. Chapters cover resistance and susceptibility to plant pathogen, strategies involving phytoprotectants, and life span of nematode affected by ROS. This book includes a compilation of recently written, integrated, and illustrated reviews describing latest information on ROS. Chapters incorporate both theoretical and practical aspects of plant ROS.Reactive oxygen species (ROS) are key signaling molecules involved in the redox equilibrium and biological processes. In plants, ROS play an important role in biotic and abiotic stress sensing, integration of diverse environmental signals, and commencement of stress-response networks, thus contributing to the establishment of defense mechanisms and plant resilience. Critical amount of ROS is required by plants for regular operation of vital physiological mechanisms.This book brings together a compilation of latest research work on reactive oxygen species and their emerging importance. The book is a useful read for students, researchers, and scientists in the field of agri-life sciences.