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The starting point of this book is the generally shared observation that in violence-torn areas of limited statehood, the civilian population is often subject to deliberate attacks. This violence often escalates to core crimes such as war crimes, crimes against humanity and even genocide. The International Criminal Court (ICC) could potentially deter such crimes. In order to do so, it largely depends on the cooperation of the states on the territory of which alleged core criminals operate. Since such states are often unwilling or unable to cooperate, the book explores whether the ICC could instead seek assistance from international forces such as UN peace support operations, UN-mandated missions, and belligerent occupants.The book covers, on the one hand, the law and practice of the UN Security Council with regard to mandating international forces to arrest and transfer alleged offenders to the ICC or to other international courts. On the other, it addresses to what extent international forces may or must hand alleged offenders over to the ICC, regardless of such mandates. More precisely, the book examines whether the duties to prosecute genocide, torture, enforced disappearance, grave breaches and other war crimes apply extraterritorially and ¿ if so ¿ whether international forces can discharge these duties by transferring suspects to the ICC.At the same time, the book addresses the limitations to such extraterritorial action: firstly, to what extent the prohibition of the use of force and the principle of territorial sovereignty restrict extraterritorial deprivations of liberty and transfer to the ICC. Secondly, it explores the restrictions and permissions that the law of occupation and other norms of international humanitarian law impose on such apprehensions and transfers. Finally, it discusses how international forces can uphold the right to liberty and security as well as the principle of non-refoulementwhen they extraterritorially apprehend ICC suspects. This also reflects the book¿s relevance with regard to the more general debate on the extraterritorial application of human rights.

This book analyses issues surrounding the efficient integration of demand response programmes in residential communities. It also explores the benefits and energy efficiency co-ordination corresponding to demand response service in a cooperative system. The author explains how sensors, communication technologies, computational ability, and control can be effectively combined to create a demand planification system. Smart appliances (SAs) and other connected devices, together with smart communities (SCs)¿which enable energy consumers to pursue common goals through cooperation and coordinated behaviour within the framework of the Internet of things (IoT)¿have raised expectations regarding deployment of the information and communication technologies (ICTs) to encourage uptake of demand response (DR) energy efficiency programmes. DR programmes pursue a reduced carbon footprint, balanced supply and demand, and behavioural change in consumers. The book provides sustainable evidence of ICT-supported energy management that can help consumers flexibly manage demand through the formation of sustainable SCs that maximise renewable energy use through large-scale cooperative management mechanisms. SCs cooperating securely in identifying consumption patterns can foster sustainable and efficient energy use, with the outcome of benefits for the participants and for the environment.

This book reviews math topics relevant to non-mathematics students and scientists, but which they may not have seen or studied for a while. These math issues can range from reading mathematical symbols, to using complex numbers, dealing with equations involved in calculating medication equivalents, the General Linear Model (GLM) used in e.g. neuroimaging analysis, finding the minimum of a function, independent component analysis, or filtering approaches. Almost every student or scientist, will at some point run into mathematical formulas or ideas in scientific papers that may be hard to understand, given that formal math education may be some years ago. In this book we will explain the theory behind many of these mathematical ideas and expressions and provide readers with the tools to better understand them. We will revisit high school mathematics and extend and relate this to the mathematics you need to understand the math you may encounter in the course of your research. This book will help you understand the math and formulas in the scientific papers you read. To achieve this goal, each chapter mixes theory with practical pen-and-paper exercises such that you (re)gain experience with solving math problems yourself. Mnemonics will be taught whenever possible. To clarify the math and help readers apply it, each chapter provides real-world and scientific examples.In this new edition, two new chapters covering statistics and differential equations have been added, which have been workshopped in the 'authors' popular lecture series in order to maximize the benefit for readers.

This book examines mindfulness-based programs for children and adolescents with diverse needs as well as their parents and other family members. It addresses how a mindfulness approach has been translated to this specific population. Chapters explore theories and evidence in this growing field of interest, adaptations for children and teens with different diagnoses and their families, mindful parenting in relation to the developmental needs of children, implementation issues in everyday life, and the required competencies of mindfulness instructors. Key areas of coverage include:Application of mindfulness-based programs to address the developmental tasks and diverse needs of children and adolescents encountering challenges in mental health and social care.Mindfulness-based programs for parents and teachers and their impacts on children.Implementation science and ethics of mindfulness training across child developmental stages. Mindfulness for Children, Adolescents, and Families is an essential resource for researchers, professors, and graduate students as well as clinicians, therapists, and allied practitioners in developmental psychology, school psychology, child and adolescent psychology, social work, public health, pediatrics, complementary and alternative medicine, and all related disciplines.

This book analyses the British government¿s use of cultural diplomacy in South Africa from 1960 to 1994. Previously, scholarship on UK-South African relations has focussed mainly on political, economic, or military links; this book makes an important and original intervention by emphasising how the British government sought to use cultural ties as part of its diplomacy in South Africa. The book also highlights the controversy these links generated owing to broader international efforts to ostracise South Africa owing to the racist apartheid system in the country at the time. By examining British policy towards educational exchanges, performing arts tours, radio and television broadcasts, and sporting contact, this book provides a dynamic case study from which to analyse Britain¿s use of cultural diplomacy during a period of relative decline, while also adding a new layer to the well-established literature on the UK-South African special relationship.

Despite its complexity, innovation is often depicted within academic literature as a phenomenon that is innately good and always necessary. This thought-provoking volume presents a more nuanced view ¿ through a number of paired chapters for and against, as well as more general critiques of innovation and several suggested new lines of inquiry, the book will be of interest to all with a broader interest in innovation.

This second edition provides new and updated methods for establishing reliable and reproducible experimental models of cardiovascular diseases. Chapters detail practical protocols from expert laboratories focusing on cardiovascular research, that would be critical in exploring novel discoveries in cardiac biology, and the development of effective therapeutic approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Experimental Models of Cardiovascular Diseases: Methods and Protocols, Second Edition aims to provide detailed and practical protocols that will be valuable tools for researchers in cardiology to conduct their research.

This fully updated volume explores N-Methyl-D-aspartate receptors (NMDARs), and the structure-function relations, principles, and rules that govern how NMDARs operate in brain processing under normal and pathological conditions. With chapters from leading laboratories around the world, this book examines the expression and purification of diverse NMDA receptor subtypes, gene targeting and generation of conditional NMDAR mutant mouse lines, studies of NMDARs in zebrafish, electrophysiological studies, NMDARs modeling in silico, drug development with artificial intelligence, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, NMDA Receptors: Methods and Protocols, SecondEdition serves as an ideal guide to the diversity of possible approaches in the field of NMDARs and the progress that has been made in recent years.

This volume explores recent innovations across the entire pipeline of imaging signal transduction, cell preparation, cellular manipulation, image acquisition, and computational analysis. The chapters in this book cover topics such as rapid preparation of living Drosophila pupal macrophages for ex vivo imaging; controlling the potency of T cell activation using an optically tuneable chimeric antigen receptor; in situ imaging of proteins using DNA-PAINT super-resolution microscopy; reconstructing signaling networks using biosensor barcoding; and morphological, spatial, and dynamic models for cellular components. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and authoritative, Imaging Cell Signaling is a valuable resource that provides guidance to researchers looking to learn how to effectively tailor design projects to image, manipulate, and model signal transduction.

This second edition provides new and updated chapters covering computational and mathematical techniques and concepts related to the field of comparative genomics. The topics covered in the chapters range from those that address general techniques and concepts that apply to all organisms to others that are specialized and apply to specific biological systems such as viruses, bacteria, nematodes, and insects. Well-known comparative genomics web-based platforms are also covered in specific chapters. Written in the highly successful Methods in Molecular Biology series format, many chapters include introductions to their respective topics and step-by-step comparison procedures, demonstrated on actual sets of genome sequences.Authoritative and cutting-edge, Comparative Genomics: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.

This comprehensive volume provides balanced and easily readable chapters on contemporary topics around discourse production in patients with neurogenic disorders. Discourse broadly refers to a unit of language longer than a single sentence, typically used in a spoken or written format to express ideas, feelings, and opinions or to interact with others. As the field of research in speech-language pathology, aphasia and related neurogenic disorders, and clinical decision-making to manage neurogenic impairments is rapidly expanding, there has been an increased focus on discourse analysis and therapy to enable patients to speak well again. Various user groups and people with lived experience (e.g., aphasia, dementia, traumatic brain injury, right hemisphere damage, etc.) are also increasingly focused on the impact of neurogenic impairments on domains of conversation and changes in language skills beyond the smaller linguistic components of single words and sentences that are traditionally supported by speech-language therapy. The first part of this book details and discusses the basic principles, historical perspectives (history and developmental milestones), neural basis, and recent evolutions and advancement of discourse analysis in speakers with acquired communication disorders. The second part of the book outlines and illustrates current methods for discourse elicitation and analysis across different clinical populations. Recent leaps forward in technology that can assist in the recording, processing, and analysis of discourse will be highlighted. The final part of book reviews and summarizes key developments of various evidenced-based training strategies, interventions, and treatment programs, as well as utilization of innovative technology to clinically improve neurogenic disordered discourse.¿This is an ideal guide for researchers, clinicians, and students in the field of communication sciences and disorders, speech and language therapy, gerontology, (neuro-)linguistics, psychology, and related fields in clinical medicine.

Sustainable Engineering: Concepts and Practices provides insights into current perspectives on sustainable engineering research. It highlights the drivers, motivations, and challenges affecting the development and adoption of sustainable engineering in various sectors of the economy and how they impact sustainable development. Contributions from researchers representing multiple branches of engineering in academia, government laboratories, and industry present alternative approaches to traditional engineering practices. These approaches effect change, making the design, construction, production, and management of products, processes, and systems more environmentally friendly, socially beneficial, and economically profitable. The book will be a trusted reference for graduate students, practicing engineers, and other professionals interested in developing or using sustainable products and systems.

The volume is part of World Geomorphological Landscapes series and shows characteristic landscapes and landforms of Poland. It consists of two parts, general and regional. The first part includes overviews of geological history, Quaternary, climate and its impact on landforms, geomorphological division of the country, geoheritage and geoconservation. The second part comprises more nearly 40 region-specific studies to show the diversity of landscapes, from high-mountain relief through medium-altitude forested ranges, limestone uplands and loess plateaus, lowland landscapes moulded by past ice sheets, rivers and aeolian processes, to coastal sceneries. Selected examples of anthropogenically modified landscapes are also considered. Each chapter is accompanied by photographs, maps and diagrams. The volume is intended primarily for geographers and Quaternary geologists, but will be also of interest to anyone interested in natural landscapes and their conservation.