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This book focuses on EU-MERCOSUR relations from a diplomatic and trade perspective against the background of the political agreement between the two in 2019. The authors take into consideration that EU-MERCOSUR cooperation developed during recent decades has tried, on the one hand, to build a strategic partnership to respond to the main challenges of international agendas and, on the other, to incorporate in Latin American countries the European new vision of transatlantic regionalism. Starting from a historical perspective of the development of interregionalism between the EU and MERCOSUR, the book goes on to study the geopolitical impacts of Brexit, stagnation of the EU-USA relationship, the COVID-19 pandemic, and of new geopolitical players in EU-LAC interregionalism. It discusses the legal institutional framework of the EU-MERCOSUR relations and provides a comparative view of features of MERCOSUR countries vis-à-vis the European Union. The book also analyses and provides a comprehensive overview of various aspects of interregional trade in the context of the 2019 agreement. Highly topical and authored by experts in this field, this book is of interest to a wide readership in the social sciences and economics: from political sociology to international relations, diplomacy studies and international trade.

This book presents intelligent methods like neural, neuro-fuzzy, machine learning, deep learning and metaheuristic methods and their applications in both volcanology and seismology. The complex system of volcanoes and also earthquakes is a big challenge to identify their behavior using available models, which motivates scientists to apply non-model based methods. As there are lots of seismology and volcanology data sets, i.e., the local and global networks, one solution is using intelligent methods in which data-based algorithms are used.

This book focuses on current frontier-related issues such as humanitarian crises, economic crises, discrimination of migrants in certain countries, different typologies of borders such as land, maritime, air, space, and even cyberspace borders, and environmental protection of water resources at borders. It addresses legal and theoretical considerations and presents empirical cases showing the manifestations of the concept in the real world and its dynamics. Without claiming to exhaust the debate on frontiers, especially given the breadth of the subject and the large number of viewpoints from which the phenomenon can be examined, this book intends to be a helpful source of insights for academics, university students, and others who wish to explore the complex and multifaceted worlds that emerge, particularly in a globalized society, from the interaction between the various actors and scenarios that shape the reality of frontiers.

This book by Jonathan Turner and Anthony Roberts proposes a new theoretical approach for explaining the dynamics of inter-societal systems. The authors argue that inter-societal systems have existed since the beginning of human societies and the dynamics of these systems are a fundamental property of the social universe. However, while world-systems analysis has emphasized this latter point, the authors argue the reluctance to theorize complex abstract models and systems of explanatory propositions on the dynamics driving inter-societal systems hinders scientific explanation of inter-societal dynamics. In this context, the authors critically look at contemporary theorizing and review key theories that have been developed to explain geo-economic, geo-political, and geo-cultural dynamics, from the classic period through present-day world-systems analysis and cliometrics. The book summarizes these theories clearly, emphasizing their strengths and weakness, finally developing a theoreticalsynthesis through new models and propositions on the dynamics of premodern and modern inter-societal systems.Professor Turner¿s decades of experience writing theory books for undergraduates have ensured that this book presents abstract ideas clearly and with examples so that students can understand the arguments. This book is a must-read for all social theory researchers, academics, serious undergraduate students, graduate students, and interested laypersons.

The 3rd edition of this textbook offers clear explanations of optical spectroscopic phenomena and shows how spectroscopic techniques are used in modern chemistry, biochemistry and biophysics.Topics included are: electronic and vibrational absorption fluorescence symmetry operations and normal-mode calculations electron transfer from excited moleculesenergy transferexciton interactions electronic and vibrational circular dichroismcoherence and dephasingultrafast pump-probe and photon-echo spectroscopy single-molecule and fluorescence-correlation spectroscopyRaman scatteringmultiphoton absorption quantum optics and non-linear opticsentropy changes during photoexcitationelectronic and vibrational Stark effects studies of fast processes in single moleculestwo-dimensional electronic and vibrational spectroscopyThis revised and updated edition provides expanded discussions of laser spectroscopy, crystal symmetry, birefringence, non-linear optics, solar cells and light-emitting diodes. The explanations are sufficiently thorough and detailed to be useful for researchers, graduate students and advanced undergraduates in chemistry, biochemistry and biophysics. They are based on time-dependent quantum mechanics, but are developed from first principles so that they can be understood by readers with little prior training in the field. Additional topics and highlights are presented in special boxes in the text. The book is richly illustrated with color figures throughout. Each chapter ends with a section of questions for self-examination.

This volume presents a series of case studies, at different levels of inclusivity, of how organisms exhibit functional convergence as a key evolutionary mechanism resulting in responses to similar environmental constraints in mechanically similar ways. The contributors to this volume have selected and documented cases of convergent evolution of form and function that are perceived to be driven by environmental abiotic and/or biotic challenges that fall within their areas of expertise. Collectively these chapters explore this phenomenon across a broad phylogenetic spectrum. The sequence of chapters follows the organizational principle of increasing phylogenetic inclusivity, rather than the clustering of chapters by perceived similarity of the phenotypic features or biomechanical challenges being considered. This is done to maintain focus on the evolutionary phenomenon that is the primary subject matter of the book, thereby providing a basis for discussion among the readership about whatis necessary and sufficient to justify the recognition of functional convergence. All chapters stress the need for integrative approaches for the elucidation of both pattern and process as they relate to convergence at various taxonomic levels.

This book provides a concerted supply chain perspective for dealing with pandemics on the scale of COVID-19. Specifically, this book describes a new approach, supply chain immunity, to illustrate what is needed to fix our economy and healthcare systems. The authors of this book are experts in supply chain management, health care supply chains, major systems acquisition, and contingency sourcing methods. Based on first-hand experiences working during COVID in the depths of the nation¿s supply chain failures, the authors develop important themes for private and public sector supply chain managers to consider in rebuilding a more immune supply chain. The book is targeted at policy makers, academics, practitioners, and students of disaster response, public policy, healthcare, and supply chain management who are interested in learning contemporary lessons from the COVID-19 pandemic. From the perspective of those who lived through the chaos, the authors furtherexplore the application of novel concepts in joint planning, market intelligence, and governance related to a national pandemic or other global contingency.

This textbook describes the most relevant molecular and biological processes in cancer, how they contribute to the development and progression of individual cancer types in humans, and how insights from molecular cancer research can be applied to improve cancer prevention, diagnostics and treatment. Part I of the textbook summarizes the current fundamental knowledge on the general properties of cancers, the causes of cancer, cancer genetics, genomics and epigenetics. Individual chapters address the functions of DNA damage and repair, oncogenes and tumor suppressors in carcinogenesis and discuss crucial mechanisms in cancer pathogenesis, such as apoptosis and replicative senescence, as well as the most relevant signal transduction pathways and regulatory networks. Part I concludes with a chapter on tumor invasion and metastasis and tumor immunology. In Part II, the most relevant mechanisms acting in individual human cancers (and subtypes) are described in more detail. This central part of the book contains individual sections on the most common human cancers highlighting the diversity in their genetic, molecular and cellular pathogenic mechanisms. How insights from molecular cancer research are translated into improvements in prevention, diagnosis, and treatment is outlined in Part III. This new edition has been extensively revised and includes in particular updated information on cancer genomics, epigenetics, viral carcinogenesis, cancer diagnostics and cancer therapy and a new chapter on lung cancers.Now more than ever, cancer research is an interdisciplinary endeavor that requires a basic knowledge of commonly used terms, facts and concepts. The aim of this book is to provide advanced students and practitioners in various disciplines with this foundation, bridging the gap between standard textbooks of molecular biology, pathology and oncology on the one hand and the specialized cancer literature on the other.

This updated and expanded second edition reviews numerous aspects of the marine microbiome and its possible industrial applications. The marine microbiome is the total of microorganisms and viruses in the ocean and seas and in any connected environment, including the seafloor and marine animals and plants. In the first part of the book, diversity, origin and evolution of the marine microorganisms and viruses are discussed. The microbes presented originate from all three domains of life: Bacteria, Archaea, and Eukarya. The second part sheds some light on the different communities: it describes marine habitats and how their inhabitants control biogeochemical cycles. The third part finally examines the microbial ocean as a global system and evaluates methods of utilizing marine microbial resources. Adopting a translational approach, the book connects academic research with industrial applications, making it a fascinating read and valuable resource for microbiologists from both domains.

The latest edition of this volume features an extensively revised and expanded collection of immunohematology and transfusion medicine case studies, comprised of clinical vignettes and antibody panels with questions following each case. Arranged in a workbook format, the text presents cases based on real patient problems and covers a number of common issues and challenging problems in blood banking and transfusion practice. Discussion and resolution of each case is provided in a separate answer section, including up-to-date information on pertinent advances in the field. This third edition updates information on existing case chapters and references and adds a variety of new case chapters. The enhanced title of this edition reflects upon the wider array of covered topics, including in-depth case studies of hemostasis and a second section with blood donation and cellular therapy topics. New features include a key to covered topics for each case and a case-difficulty rating scale. Written by experts in the field, Immunohematology, Transfusion Medicine, Hemostasis, and Cellular Therapy: A Case Study Approach, Third Edition is an interactive tool that makes blood banking and transfusion medicine memorable, practical, and relevant to residents, fellows, laboratory technologists, and anyone interested in gaining and updating their knowledge in the field

This textbook provides up-to-date content in the fields of system engineering, system safety and functional safety, with up-to-date examples from the automotive, industrial and aerospace domains, with respect to the growing complexity of the field and the increased utilization of complex hardware and software in vehicle designs. The book covers practical functional safety insights concerning the required standards (e.g. IEC 61508, IEC 62061, ISO 13849, ISO 26262), but also inherent system safety process as a key factor towards the mitigation of systematic faults. Readers will be equipped with a broad understanding of safety and functional safety, with balanced theoretical and practical views in this area.The book covers the specific topics of introduction to system engineering, overall system safety and its relation to functional safety. Functional safety is introduced in all the required concepts, terminology and safety analysis methods. Basic fault-tolerance concepts arecovered, including the design considerations to achieve functional safety. The book also gives an introduction to the required system safety processes and the applications of relevant functional safety standards.

This comprehensive textbook explores the boreal forests of Northern Europe, Finland, Sweden and Norway. Students will gain an overview of the forest ecosystem and the services it provides for modern society. From the production of timber, to the supply of food products or their use as a recreational space for human wellbeing - our forests serve many needs. Accordingly, the respective chapters cover various types of ecosystem service, e.g. supporting, provisioning, regulating and cultural services.The book's main focus is on the management of boreal forests for the production of these ecosystem services. Addressing modern challenges, e.g. managing vulnerable boreal forests for adaptation to climate change, is an important aspect throughout the volume. Traditional forest management has to adapt and evolve in order to meet the increasing risk of abiotic and biotic damages to our forest biomass. Future forestry graduates will have to face more and more of these challenges; consequently, the book provides them with a wealth of scientific knowhow and possible counter-strategies.Forestry students in the Northern Hemisphere, be it in Europe, North America or Asia, will find this book an excellent reference guide. To make the content more accessible, it has been enriched with a clear structure, numerous illustrations and learning objectives.

This Handbook aims to provide a unique and convenient one-volume reference work, exhibiting the latest interdisciplinary explorations in this urgently burgeoning field of intellectual and practical importance. Due to its immense range and diversity, environmental politics and theory necessarily encompasses: empirical, normative, policy, political, organizational, and activist discussions unfolding across many disciplines. It is a challenge for its practitioners, let alone newcomers, to keep informed about the ongoing developments in this fast-changing area of study and to comprehend all of their implications. Through the planned volume¿s extensive scope of contributions emphasizing environmental policy issues, normative prescriptions, and implementation strategies, the next generation of thinkers and activists will have very useful profiles of the theories, concepts, organizations, and movements central to environmental politics and theory. It is the editors¿ aspiration that this volume will become a go-to resource on the myriad perspectives relevant to studying and improving the environment for advanced researchers as well as an introduction to new students seeking to understand the basic foundations and recommended resolutions to many of our environmental challenges. Environmental politics is more than theory alone, so the Handbook also considers theory-action connections by highlighting the past and current: thinkers, activists, social organizations, and movements that have worked to guide contemporary societies toward a more environmentally sustainable and just global order.Chapter ¿Eco-Anxiety and the Responses of Ecological Citizenship and Mindfulness¿ is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book is a collection of contributions covering the major subjects in numerical simulation of space and astrophysical plasma. It introduces the different approaches and methods to model plasma, the necessary computational codes, and applications in the field. The book is rooted in the previous work Space Plasma Simulation (Springer, 2003) and includes the latest developments. It is divided into three parts and all chapters start with an introduction motivating the topic and its use in research and ends with a discussion of its applications. The chapters of the first part contain tutorials of the different basic approaches needed to perform space plasma simulations. This part is particularly useful for graduate students to master the subject. The second part presents more advanced materials for students and researchers who already work with pre-existing codes but want to implement the recent progresses made in the field. The last part of the bookdiscusses developments in the area for researchers who are actively working on advanced simulation approaches like higher order schemes and artificial intelligence, agent-based technologies for multiscale and multi-dimensional systems, which represent the recent innovative contributions made in space plasma research.

This book is a contribution to the research community towards thinking and reflecting on what Responsible Machine Translation really means. It was conceived as an open dialogue across disciplines, from philosophy to law, with the ultimate goal of providing a wide spectrum of topics to reflect on. It covers aspects related to the development of Machine translation systems, as well as its use in different scenarios, and the societal impact that it may have. This text appeals to students and researchers in linguistics, translation, natural language processing, philosophy, and law as well as professionals working in these fields.

This volume examines evolving trends and transnational perspectives on public interpretation of archaeological and cultural heritage, as well as levels of communication, from local to regional, national and international. It is presented in the context of the evolution of cultural heritage studies from the 20th century "e;expert approach"e; to the 21st century "e;people-centered approach,"e; with public participation and community involvement at all phases of the decision-making process. Our premise is not just about bringing in community members to be partners in decision making processes; some projects are being initiated by the community--not the heritage experts. In some instances, community members are central in initiating and bringing about change rather than the archaeologists or heritage specialists. In several cases in the book, descendants take the lead in changing heritage narratives.The book addresses several central questions: Do these actions represent new emphases, or more fundamental pedagogical shifts, in interpretation? Are they resulting in more effective interpretation in facilitating emotional and intellectual connections and meanings for audiences? Are they revealing silenced histories? Can they contribute to, or help mediate, dialogues among a diversity of cultures? Can they be shared experiences as examples of good practice at national and international levels? What are the interpretation and presentation challenges for the future?Cultural heritage, as an expression of a diversity of cultures, can be an important mediator between pasts and futures. In the past, people in power from the dominant ethnic, racial, socio-economic, gender, and religious groups determined the heritage message. Minorities were often silenced; their participation in the building and growth of a city, county, or nation's history was overlooked. New philosophical/methodological trends in public interpretation are reshaping the messages delivered at archaeological/cultural heritage sites worldwide. The role of the experts, as well as the participatory engagement of audiences and stakeholders are being redefined and reassessed.  This book explores these processes, their results and effects on the future.

This book focuses on childhood psoriasis; it comprehensively discusses various concepts and topics related to this widespread auto-immune disease, including its pathogenesis, clinical aspects, the most recent and proven therapeutic approaches as well as the management of the psychological burden generated in younger patients. By highlighting the latest information on the pathogenic mechanisms, this unique book illustrates the great variety of clinical manifestations of this condition in pediatric patients, which are often very different from those in adults and later onset cases. It describes state-of-the-art therapeutic approaches and the advantages and limitations of latest treatment options available, and also presents all comorbidities of the disease in childhood, focusing on cardiovascular and metabolic disorders, as well as on the psychological impact of the disease in both children and adolescents. Including over 90 original full-color illustrations, this book raises dermatologists' and pediatricians' awareness of this disease, which is increasingly being diagnosed during childhood. It also provides practical tools for best management. This clear, concise guide is intended for dermatologists, pediatricians, clinicians and researchers as well as residents in dermatology and pediatrics, but will appeal to all readers wanting to update their understanding of psoriasis in childhood.

The volume comprises a variety of research approaches that seek to explore and understand employees' learning and development through and for work. Working life reveals challenges through technological, economic and societal development that can only rudimentarily be addressed by formal education and training. Workplace learning becomes more and more important for employees and enterprises to successfully cope with these challenges.Workplace learning is a steadily growing field of educational research but it lacks so far a scholastic canon - there is rather a diversity of research approaches. This volume reflects this diversity by bringing together researchers from different countries and different theoretical backgrounds, presenting their current research on topics that all are relevant for understanding presages, processes and outcomes of workplace learning. Hence, this volume is of relevance for researchers as well as practitioners in the field and policy makers.

This book provides a systematic account of media and communication development in Soviet society from the October Revolution to the death of Stalin. Summarizing earlier research and drawing upon previously unpublished archival materials, it covers the main aspects of public and private interaction in the Soviet Union, from public broadcast to kitchen gossip. The first part of the volume covers visual, auditory and tactile channels, such as posters, maps and monuments. The second deals with media, featuring public gatherings, personal letters, telegraph, telephone, film and radio. The concluding part surveys major boundaries and flows structuring the Soviet communicate environment. The broad scope of contributions to this volume will be of great interest to students and researchers working on the Soviet Union, and twentieth-century media and communication more broadly.