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  • av Birgit Suberg
    649,-

    Dieses Buch konzentriert sich auf die Rolle des Beirats oder ähnlicher Governance-Gremien in Familienunternehmen und speziell auf Prozesse und Themen von strategischer Bedeutung. Es umfasst alle relevanten Themen, die regelmäßig behandelt werden müssen, wie Strategieentwicklung, Finanzmanagement und Führung. Zu jedem Thema werden die Vor- und Nachteile herausgearbeitet. Dies ist eines der wenigen Bücher, das sich mit Familienunternehmen befasst, von den Governance-Systemen bis hin zur Rolle der Führungskräfte. Die von den Autoren sorgfältig gesammelten Beispiele und die eingehende Diskussion der Themen bieten dem Leser wertvolle Einblicke, um die Wirksamkeit der Unternehmensführung zu bereichern.

  • Spar 14%
    av James Wierzbicki
    1 335,-

  • Spar 16%
    av Thorsten Wahlers
    2 145,-

    This book should represent a guideline for launching an extracorporeal membrane oxygenation (ECMO) program. It describes in detail particularities and special features of planning, setting up, developing, structuring and maintaining of ECMO support program for instable patients with the need of transportation from peripheral hospitals to an experienced ECMO centre for further treatment.Authors have condensed both the current evidence and Guidelines on ECMO and eCPR support and have highlighted in detail the issue of planning, setting up, developing, structuring and maintaining this program with the view to helping other centres launching this life-saving service taking into account their experience in this important field of medicine. In this context, the main benefit of this book is the outstanding and particular aim to educate the reader in developing and maintaining a large-spectrum ECMO program. The volume, richly illustrated and written by KOLs using an expository writing style to promote the readability will appeal to intensivists, anesthesiologists and cardiologists as well as cardiac- and thoracic-surgeons and pneumologists

  • Spar 17%
    av R. Jayakumar
    3 302

    This volume deals with the various fabrication techniques, surface functionalization and biomedical applications of polymeric fibers possessing different scale and structure. It provides an overview of fabrication techniques such as Co-axial, Centrifugal, Melt and Yarning to procure multiscale, tubular and layered fibrous scaffold employed for biomedical applications. The chapters in this volume discusse the surface/chemical functionalization of fibers which enhance the biological properties of the fibrous scaffolds as well as the development of hybrid, layered and external stimuli-responsive fibrous scaffolds that hold potential application in biosensor and other biomedical fields. In addition, recent advances and applications of polymeric multiscale fibers in tissue engineering, regenerative medicine and drug delivery are presented. The potential use of fibrous scaffolds in bone, neural, tendon/ligament and cardiac tissue engineering, nanofibers as an antimicrobial wound dressing, employed in cancer theragnostics and in the treatment of skin/periodontal infections are discussed. The volume provides expert knowledge on the fabrication techniques, development of different scale and hybrid structure fibers, surface functionalization, layered and external stimuli responsive fibrous scaffolds. It will be beneficial to material/biomaterials scientists, bioengineering and biotechnologists by providing a better understanding on the subject of the innovative applications of fibrous scaffolds in drug delivery, tissue engineering, wound dressings and regenerative medicine.

  • Spar 16%
    av Chen-Yu Huang
    2 145,-

    This book explains mechanical and thermal reliability for modern memory packaging, considering materials, processes, and manufacturing.In the past 40 years, memory packaging processes have evolved enormously. This book discusses the reliability and technical challenges of first-level interconnect materials, packaging processes, advanced specialty reliability testing, and characterization of interconnects. It also examines the reliability of wire bonding, lead-free solder joints such as reliability testing and data analyses, design for reliability in hybrid packaging and HBM packaging, and failure analyses. The specialty of this book is that the materials covered are not only for second-level interconnects, but also for packaging assembly on first-level interconnects and for the semiconductor back-end on 2.5D and 3D memory interconnects.This book can be used as a text for college and graduate students who have the potential to become our future leaders, scientists, and engineers in the electronics and semiconductor industry.

  • Spar 11%
    av Jack Dongarra, Roman Wyrzykowski, Konrad Karczewski & m.fl.
    756 - 1 335,-

  • Spar 13%
    av Alessandro Balestrino
    1 103,-

    This book reflects the reality of most taxpayers. It provides a comprehensive and up-to-date treatment of optimal tax issues from a household economics perspective. A unified and integrated approach is employed to analyze optimal taxation in a homogeneous way.The author adopts a household production approach to allow a critical understanding of the way tax policy impacts economic agents. This way home activities can be studied with the same toolbox normally employed for the market activities. This is motivated by the fact that in reality most agents act from within a family, and their interaction with the economy at large and tax policy in particular is mediated by the interdependence of the family members¿ choices, although taxation is typically studied in a framework in which the economic agents are isolated individuals. The aim of the book is to provide, a comprehensive treatment of family taxation whithin this approach, focusing on the normativeside ¿ social welfare maximising taxation.As a consequence of the book's analysis, many important and established results in public economics may have to be revised. The book will be useful to both graduate students and researchers alike in that it adopts a rigorous analytical language but also includes ample intuitive explanations.

  • Spar 17%
    av Mariana Amaro
    3 302

    This book provides the reader with an updated comprehensive view of the rapidly developing and fascinating field of fluorescence spectroscopy and microscopy. In recent years, fluorescence spectroscopy and microscopy have experienced rapid technological development, which has enabled the detection and monitoring of single molecules with high spatial and temporal resolution. Thanks to these developments, fluorescence has become an even more popular method in physical, biological and related fields. This book guides the reader through both basic and advanced fluorescence spectroscopy and microscopy approaches with a focus on their applications in membrane and protein biophysics. Each of the four parts: A - Fluorescence Spectroscopy, B - Fluorescence Microscopy, C - Applications of Fluorescence Spectroscopy and Microscopy to biological membranes and D - Applications of Fluorescence Spectroscopy to protein studies are written by experts within the field. The book isintended for both complete beginners who want to quickly orient themselves in the large number of existing fluorescent methods, as well as for advanced readers who are interested in particular methods and their proper use.Chapter ¿Dynamics and Hydration of Proteins Viewed by Fluorescence Methods: Investigations for Protein Engineering and Synthetic Biology¿ is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

  • av Matthew Calarco
    583,-

    Roadkill is a recurrent but often unthought feature of modern life. Yet, consideration of the broader significance of the myriad social, ethical, and political issues related to roadkill has largely gone missing from mainstream scholarship and activism. This neglect persists even in fields such as mobility studies and animal studies that would otherwise seem to have a vested interest in the topic. This book aims to bring roadkill to the foreground of current discussions among scholars and activists in these fields in order to demonstrate that roadkill is a uniquely important site from which to understand and contest the machinations of the dominant social order. It argues that a careful examination of roadkill can help both to uncover the hidden violence of contemporary human-centered systems of mobility and to develop alternative modes of mobility for a renewed social life in common with our more-than-human kin.

  • Spar 16%
    av Dimitrios Lamprou
    2 376,-

    New materials and manufacturing techniques are evolving with the potential to address the challenges associated with the manufacture of medicinal products that will teach new tricks to old drugs. Nano- and microfabrication techniques include manufacturing methods such as additive manufacturing, lithography, micro-moulding, spray drying, and supercritical fluids among many others. The increasing resolution of new techniques allow researchers to produce objects with micrometric resolutions. This book follows a consecutive order, beginning with a background in the current field and limitations in the manufacturing of different pharmaceutical products, moving on the classification of each method by providing recent examples, and future prospective on a variety of traditional and new Nano and microfabrication techniques. A focus on the materials used to prepare these systems and their biocompatibility, including applied topics such as clinical applications and regulatory aspects also covered, offering the reader a holistic view of this rapidly growing field.

  • Spar 15%
    av Stephen P. Day
    1 566,-

    This edited book provides a critical re-reading of the concept of teacher education, in addition to a re-thinking of the sole focus on Initial Teacher Education (ITE), with implications for education policy, theory, and practice. This book presents new investigations that explore the concept of teacher education from ITE to retirement and how this is being enacted within the various distinct European and international education contexts. It demonstrates teaching and teacher education as a deeply contested field within European education and within the different national contexts of Europe. Contributions in this book expose teacher education as a continuum of teacher learning that is set off from the beginning of the teachers¿ own schooling and continues throughout their entire teaching career. The chapters deal with various issues, namely teacher induction and mentoring; teacher agency; teachers as researchers; the role of the head teacher; schools as learning communities; and distinctITE practices. It is intended for postgraduate students and researchers with an interest in teaching and teacher education, educational policies and politics, and educational philosophy, as well as practitioners.

  • Spar 16%
    av Tokuro Matsuo
    2 376,-

    This book aims to share the theory and practice in innovative human/society-oriented information systems. The purpose of information technology is for people, communities, and societies, and we cannot ignore the human behavior and social features to design better information systems. The book includes the selected papers in the International Conference on Applied Informatics and Media Design 2019 (AIMD 2019) held at California State University, Bakersfield, USA, and International Conference on Applied Information Technologies 2021 (AIT 2021) held online, which are focused on information design, human¿computer interaction, and social support systems. The book also contains multi-aspect contributions on applied informatics and media engineering, such as color design, online learning, creativity support, philosophical issues, elder treatment, AI, and business informatics.

  • Spar 15%
    av Alev Yüksel Aydar
    1 682,-

    The plant-based food industry has flourished in recent years, with a steady stream of exciting product launches reaching the worldwide market. Consumers have become interested in a plant-based diet that includes grains, legumes, seeds, nuts, fruits and vegetables. There are a number of factors involved in this trend, including consumer opposition to harming animals, health problems such as lactose intolerance, desire for a healthier lifestyle and environmental awareness.Several books related to plant-based diets and cookbooks have been published for vegans and vegetarians, however there is no research work related to plant-based production, technology, ingredients and their qualitative and nutritional properties based on the results of scientific studies. Future Food: Plant-Based Products is the first book where the comparison of plant-based products with other alternatives are explored in detail. Novel plant-based product formulations, production and results of recent studies are examined in detail in this book.Plant-based products are mainly alternatives to dairy and meat products, and this text includes comprehensive chapters on meat substitutes and plant-based non-dairy products. In the opening chapter the main ingredients and raw materials used to produce a variety of plant-based products are covered along with their qualitative and nutritional properties. Further chapters focus on the health effects of plant-based products and microbiological and safety issues. For researchers seeking a full, up-to-date overview of plant-based product alternatives and their production, health affects and safety aspects, this book meets your needs.

  • Spar 16%
    av Mayken Espinoza-Andaluz
    1 913,-

    The 2022 Congress on Research, Development, and Innovation in Renewable Energies (CIDiER 2022) promotes international collaboration on ideas and dialogue around climate change solutions through research and development that leads to clean energy innovation via renewable energies. The selected papers cover both theoretical and applied research that will strengthen the implementation of renewable energy projects between universities, research centers, and private companies in Latin America.

  • Spar 14%
    av Neeraj Kumar
    1 335,-

    This book focuses on recent developments in the field of two-dimensional nanomaterials for environmental applications. Due to their high surface area and tunable surface chemistry, two-dimensional nanomaterials are currently garnering great interest for environmental remediation applications. This book compiles contributed chapters from active international researchers dealing with the development of state-of-the-art two-dimensional nanomaterials in environmental applications such as water and wastewater treatment, adsorption, photocatalysis, membrane separation, desalination, deionization, environmental pollutants sensing/detection, carbon-dioxide capture and catalytic conversion, microbial treatment, and electrochemical remediation. Each chapter provides an essential and comprehensive overview of the recent advances in material development and application, giving special attention to preparation methods, tunning of physiochemical properties, surface and interface chemistry, structural porosity, assemblies integration for fabrication of devices, and their relationship with overall efficiency. It offers a valuable reference guide for environmental and materials scientists, engineers, and policymakers working towards environmental sustainability.

  • Spar 15%
    av Martin Biel & Christian Wahl-Schott
    1 566,-

    This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level.

  • Spar 15%
    av Helene De Vos
    1 451,-

    This book explores how prison life is normalized in different countries, with a critical and detailed look at ¿Scandinavian exceptionalism¿ ¿ the idea that Scandinavian prisons have exceptionally humane conditions ¿ and compares these prisons to ones in Belgium. It provides a more nuanced, systematic and contextualized comparison of normalization in two countries. Through analyzing policy and legislative documents, participant observation and interviews, it seeks to understand how normalization is implemented differently in prison legislation, policies and practices and compares the two societies for context. It also considers the material prison environment, security, the social environment and the use of time in prison. It provides insights into how normalization can be successfully and holistically implemented in both policy and practice, to contribute to a more ¿pure¿ form of liberty deprivation as punishment without too many unintended effects.

  • Spar 15%
    av Vic Velanovich
    1 451,-

    This unique book is a major contribution to the literature on persuasion in communication, and on doctor-patient communication, in particular. Written by a physician-scientist with deep experience on the topic, the book offers a comprehensive analysis of what makes an argument in medicine persuasive, outlining the characteristics of an argument that causes people to accept that the conclusion(s) of an argument are true. Although the book focuses on medical arguments in particular, the general approach offered by the author is appropriate for any informal argument. The central emphasis is that although sound logical construction and true premises are required to establish the logical truth of a conclusion, this is insufficient for persuasion to occur. Although formal logic can exist independent of human reception, real-world arguments must have both an arguer (the individual constructing the argument) and an audience (individuals listening and evaluating the argument).Whether the audience is capable of changing their world view is as important as the logical construction of the argument, maintains the author. To illustrate all points, a plethora of examples in medical research and in diagnosis and treatment decisions are presented. Medical Persuasion: Understanding the Impact on Medical Argumentation is a unique contribution to the clinical literature and will be of immense interest to medical practitioners, researchers, and philosophers as a way of gaining insights into constructing arguments for their peers and patients. In addition, medical trainees will gain important insights in the production of medical knowledge and medical practices, and even students in the social sciences and humanities will find the work valuable as a conduit to gaining insight into the reception of an argument.

  • Spar 15%
    av Raj Mani
    1 451,-

    This book describes how chronic wounds follow a completely different healing trajectory to acute wounds and discusses the factors associated with these poor healing trajectories. These factors include age, chronic inflammation, phenotypic changes in such cells as macrophages, fibroblasts, and keratinocytes, colder, alkaline wound milieu, wound related hypoxemia, and diabetes. Other factors implicated include reperfusion injury, poor patient compliance, presence of undiagnosed and therefore unmanaged biofilms and wound pain.The past decades have yielded reliable evidence-based guidelines and standardized care, but the healing of diabetic foot wounds continues to be unpredictable notwithstanding these advances, while the recurrence rates are also high. The benefits of technology in wound diagnosis are evidence-based and the use of this technology also features in guidelines. However, the same argument cannot be extended to adjuvant devices to facilitate wound closure even though many devices potentially benefit wound healing. Chronic Wound Management describes how innovation is based on technology that itself informs evidence, the gap between the evidence available, the performance of technology and how do we bridge this gap. It reviews the lessons learnt from the COVID-19 pandemic and whether traditional medicine systems offer us real or imaginary benefits. Consequently, this book is an important addition to the literature in the area and an essential read for all healthcare professionals working with these patients.

  • Spar 14%
    av Kimani Njogu & Alamin Mazrui
    1 335,-

    This monograph examines the roles and functions of Swahili in war/conflict situations, and the impact of wars on the destiny of the language. Covering a period of over a century, the monograph explores this sociolinguistic theme in the context of six wars/conflicts: the Maji Maji resistance against German rule, the two World Wars, the anti-colonial resistance to British colonialism, the wars of the Great Lakes region, the cold wars, and the ongoing war against terrorism. In geographical focus, some of the war situations explored here are ¿local,¿ others are ¿transnational,¿ and others still rather ¿global¿ in scope and ramifications. In the final analysis, the monograph provides important snapshots of the conflict-based history of the Swahili language, demonstrating once again that language is a malleable tool that can be appropriated and galvanized to serve the interests of either party in a conflict and sometimes as a means of creating hegemonic and anti-hegemonic meanings.

  • Spar 15%
    av Allen Coin
    1 566,-

    In this volume the authors explore the landscape of thought on the ethical and policy implications of Brain Computer Interface (BCI) technology. BCI technology is a promising and rapidly advancing research area. Recent developments in the technology, based on animal and human studies, allow for the restoration and potential augmentation of faculties of perception and physical movement, and even the transfer of information between brains. Brain activity can be interpreted through both invasive and non-invasive monitoring devices, allowing for novel, therapeutic solutions for individuals with disabilities and for other non-medical applications. However, a number of ethical and policy issues have been identified from the use of BCI technology, with the potential for near-future advancements in the technology to raise unique new ethical and policy questions that society has never grappled with before. The volume has three parts: 1) Past, Present and Future of BCI technology, 2) Ethical and Philosophical Issues and 3) Legal and Policy Implications. The rich and detailed picture of the field of BCI ethics with contributors from various fields and backgrounds, from academia and from the commercial sphere may serve as an introductory textbook into the neuroethics of BCI, or as a resource for neuroscientists, engineers, and medical practitioners to gain additional insight into the ethical and policy implications of their work.

  • av Han Wang
    641,-

    This book constitutes the conference proceedings of the 10th Pacific Rim Symposium on Image and Video Technology, PSIVT 2022, held in Bintan Island, Indonesia, in November 2022.A total of 15 papers were carefully reviewed and selected from 18 submissions. The main conference focuses on theoretical advances or practical implementations in image and video technology.

  • Spar 14%
    av Ryosuke Yokoe
    1 335,-

    The relationship between alcohol consumption and liver cirrhosis has long been contested by doctors and medical professionals, creating numerous implications for the public reputation of alcohol in Britain. Despite this, it was not until the 1970s that cirrhosis came to be understood as an ¿alcoholic disease¿. This book contextualises developments in this debate through the twentieth century by examining the significant influence that medical expertise had on policy responses to alcohol misuse, as well as the social reputation of alcohol consumption. It demonstrates how the degree to which drinking was seen to be responsible for liver disease directly shaped how different groups, such as the temperance movement and the drinks industry, exaggerated or downplayed the destructive properties of alcohol. Covering a series of themes including the science of disease causation, the social standing of medical expertise, and alcohol and public health policy, this book argues that in order toproperly understand the trajectory of debates around drinking we need to consider the twentieth-century ¿alcohol problem¿ as primarily a medical issue. Contrary to the tendency by existing works to disassociate perceptions and responses to alcohol use from the objective knowledge of its effects on the body, this book shows that medical understandings of liver disease influenced how alcohol was conceptualised in relation to its harms. Offering a fresh perspective on the interaction between scientific knowledge and policy during the twentieth century, this book provides insights for those researching the social, political and cultural history of modern Britain, as well as historians of medicine and health.

  • Spar 13%
    av Arthur Langer & Arka Mukherjee
    988,-

    Most existing companies struggle currently because they lack the tools and strategies to move product departments into independent platforms that can be retrofitted to form dynamic new products based on consumer demands. This book provides managers and professionals with the necessary approaches for designing software and hardware architectures to support data platform organizations. Specifically, it demonstrates how to automate the decomposition of existing platforms into smaller parts that can be reused to form new variations. This task requires significant analysis and design methodologies and procedures to create an infrastructure based on data as opposed to products. These new knowledge bases allow data-centric professionals to pursue actions that can better predict and respond to the unexpected. Featuring case examples from companies such as Lego, FedEx, General Electric (GE), Pfizer, P&G and more, this book is appropriate for C-level executives engagedin the digital transformation of their firms; entrepreneurs of digital platform companies; and senior software engineers that need to design Internet of Things (IoT) devices and integrate them with block chain and multi-cloud architectures. In addition, this book is also useful for graduate-level coursework in data science.

  • Spar 16%
    av Falk Huettmann
    1 913,-

    This book aims to present a reality view for Papua New Guinea based on many years of first-hand field work and research accounts. It further assesses sustainability in the light of 47,000 years of a self-sustained type of civilization without bad global impacts. This book contrasts the modern sustainable development failures from the colonial times onwards, as promoted by the ¿western world¿, namely Australia, the UK, EU and the U.S as well as Japan and now, China, in times of globalization, Trump¿ism and royal governance (Papua New Guinea is still part of the British Dominion and of the Antarctic Treaty etc). This assessment and book is the first of its kind also employing modern data analysis, Landscape Ecology principles (patterns and processes, telecoupling) and Geographic Information Systems (GIS) with Open Access data focusing on ecological economics, marxism, socialism and contrasting it with current capitalism and neoliberalism that Papua New Guinea is fully exposed to. Throughout the 31 book chapters various aspects are covered how a further insistence on the ¿new¿ Sustainable Development Goals (SDGs) and so-called Development Aid will result in unwanted side effects and perverse outcomes for Papua New Guinea and for the world in times of wider ¿global change¿ and unprecedented man-made crisis.

  • Spar 15%
    av Susan T. Verghese
    1 566,-

    This case-based book comprehensively covers the clinically significant problems that can occur in children in the immediate postoperative period after surgery after admission to Post Anesthesia Care Unit. Chapter authors first focus on how clinical monitoring and safety of post-op patients can and must continue after hand off to the PACU team and then describe 24 interesting clinical scenarios that needed urgent intervention in PACU. The goal of this book is to teach members of the perioperative teams around the globe how to keep anesthesia stat calls to a minimum. Anesthesia STAT! Acute Pediatric Emergencies in PACU features contributions from leaders in pediatric anesthesiology and be an indispensable guide for the perioperative and postoperative team in preventing potential problems during the post-anesthetic period.

  • Spar 15%
    av M. D. Miller
    1 798

    This book offers a practical approach to conducting research in foreign languages on topics with a global nexus. It introduces the problem researchers face when getting started with a research problem, such as setting up the research environment and establishing goals for the research. The researcher then needs to prepares and to conduct foreign-language research by generating key terms and searching the right places where the information they seek is most likely to be stored. Using the appropriate advanced search operators, the researcher narrows down the search results to the desired sources, thereby eliminating the irrelevant sources. Specialized knowledge of country-specific domains advances the specificity and relevance of the researcher¿s efforts. The methods and tools demonstrated in this book are applicable to a variety of academic and practical fields. A doctor may ask ¿what are other experts in my field saying about ABC disease?¿ A sommelier may ask ¿where else in the world are XYZ grape varietals grown?¿ A businessman may ask ¿who are my global competitors in my market?¿ A doctoral student may ask ¿have any other students at universities abroad ever written a dissertation about my topic, too?¿ With the tools and techniques demonstrated in this book, all of these questions are answerable. This book concludes with chapters on translation and citation methods, and includes three case studies that demonstrate the practical use of the methods discussed above. This book targets academic researchers as well as students and faculty. This book will also be a good fit as an assigned reading for a college course on thesis/dissertation research.

  • Spar 16%
    av Eduardo A. Haddad
    1 913,-

    This book examines regional structural challenges on Colombiäs path to sustainable social cohesion and regionally inclusive growth. These challenges can be divided into three main groups: (i) those that focus on competitiveness and the supply side, (ii) those that arise from critical business cycle issues on the demand side, and (iii) those concerning environmental sustainability, employment and social inclusion. The contributions, written by experts on Latin American economics and regional science, apply quantitative simulations based on a unified general equilibrium framework and address a wide range of topics, including: Colombiäs competitive integration in global markets, human capital profiles, regional economic disparities and public and private mechanisms of interregional income transfer. The challenges entailed by such high-profile and long-term issues as productivity growth and climate change are also analyzed. In addition, the book positions Colombiäs experiences in an international comparative context. It argues that many other Latin American countries face similar challenges and provide evidence to substantiate this claim. By doing so, it offers valuable policy lessons for Latin American countries with similar difficulties.

  • Spar 15%
    av Andrés Santa-María
    1 451,-

    This book gives insight into the ongoing work of the forum on Philosophy, Engineering and Technology (fPET), which brings together philosophers and engineers from all over the world to discuss philosophical issues of engineering across disciplinary boundaries. Drawing on presentations and conversations at the fPET 2020 online conference hosted by the Universidad Técnica Federico Santa María in Chile, the chapters establish connections and describe discoveries that have so far been neglected in the discussions held within the young discipline of philosophy of engineering. This volume appeals to students and researchers in the field, through twenty-four proposals brought forward by leading scholars and emerging voices. Pertinent themes covered are:the broader engagement of engineers in problem-solving beyond the scope of their own professionthe exploration of new goals for technology development and the implementation of strategies to reach these goalsthe need for philosophical content and unique pedagogical approaches to engineering education, digital transformations, artificial intelligence and the ethics of online collaboration in social mediacritical revisions of fundamental terminology and theoretical modelling of key concepts in engineering design, ethics, innovation and the anthropology of technology

  • Spar 16%
    av Mark E. Warchol
    1 913,-

    This volume provides a detailed update on progress in the field of hair cell regeneration. This topic is of considerable interest to academicians, clinicians, and commercial entities, including students of auditory and vestibular neuroscience, audiologists, otologists, and industry, all of whom may have interest in hair cell regeneration as a potential future therapy for hearing and balance dysfunction. In 2008, Springer published a SHAR volume on this subject (Hair Cell Regeneration, Repair, and Protection, Editors Richard Salvi and Richard Fay). Since that time, there has been considerable advancement in this field.This book provides a historical perspective on the field, but the emphasis is on more "prospective" views of the various facets of regeneration research, in the hope that the volume will stimulate new projects and approaches, focusing on the limitations of current knowledge and describing promising strategies for future work. The book will include thefollowing key features of hair cell regeneration:¿ Cellular and molecular control hair cell regeneration in non-mammalian species (in particular zebrafish and chickens) ¿ Our current understanding of the capacity for hair cell replacement in mammals (rodents and humans). ¿ Signals controlling pro-regenerative behaviors in supporting cells, the hair cell progenitors. ¿ New techniques that have been applied to study the genetic and epigenetic regulation of hair cell regeneration in mammals and non-mammals. ¿ Contributions of stem cells toward building new tools to explore how hair cell regeneration is controlled and toward developing cells and tissue for therapeutic transplantation. ¿ Studies that have applied gene and drug therapy to promote regeneration in mammals.

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