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This monograph presents an overview of the lysosome and its different roles in the maintenance of cellular homeostasis. It also provides a description of the various pathophysiologic changes associated with the lysosomal storage disorders. Therapeutic considerations and aspects relating to genetic counselling are covered in the final section. Several diagrams are provided to facilitate greater understanding of relevant themes. Additionally, contextual material is given at the end of each chapter, which elaborates on some of the entries brought up in the discussions. The book is written by an expert in the field who has been engaged in basic and clinical research. It offers a broad perspective and should appeal to both novices and experts in the field who seek a single resource that provides a comprehensive examination of the relevant topics. Issues covered should appeal to both the basic scientist and the clinician.

The use of essential oils by civilisations constitutes a common practice since antiquity. In earlier times, China, India and the Middle East used herbs and oils in cooking, cosmetics, medicine and in religious rituals. These substances come from a secondary metabolism of plants and are associated with several functions necessary for their survival, such as the defense against microorganisms, predators and attraction of pollinators. Essential oils are composed of a complex mixture of biologically active substances, lipophilic and volatile, and in most cases derivatives of terpene compounds and in a lower occurrence - phenylpropanoids. They have been long recognised for their medicinal uses: antibacterial, antifungal, antiviral, insecticidal and their antioxidant properties. The increased interest in alternative natural substances is driving the research community to find new uses and applications of these substances. This book provides research on the historical significance, chemical composition and medicinal uses and benefits of essential oils. Some of the topics discussed include extraction methods of essential oils; an overview of the most relevant essential oil changes regarding plant phenology and plant development; the antibacterial properties of some essential oils; essential oils applications in agriculture; and the use of essential oils as additives in broiler diets.

The first chapter in this fourth volume of "Climate, Energy, and Environment: Issues, Analyses, and Developments" presents current topical research in the study of green building services, which include construction, architecture, engineering, and related activities aimed at creating sustainable structures using environmentally responsible processes and materials. Chapter Two discusses industry trends, global competition, and federal support of U.S. solar photovoltaic manufacturing. Chapter Three identifies the mechanisms behind the surprising decline in U.S. petroleum consumption relative to both recent levels and past projections. Chapter Four discusses the scientific understanding of the effects of ocean acidification; the extent to which federal agencies have implemented the Federal Ocean Acidification Research and Monitoring Act of 2009 (FOARAM); and additional actions, if any, that could be taken to advance the federal response to ocean acidification. Chapter Five provides a summary of recommendation for carbon dioxide storage in unconventional reservoirs workshop. Chapter Six concludes this volume with a description of the issues facing corrections policy and leadership as the impacts of climate change and its related consequences confront departments, agencies, and facilities in coming years.

Critical thinking, being a general competency, is usable in different professions and areas of human life. In most professions, the crucial ability is to be capable of problem-solving and decision-making. If one needs to make a decision, it is the critical thinking aspect that is most helpful in making the right decision. Nowadays, much more important than to know how to find information is the ability to meaningfully process it. Critical thinking includes higher-order cognitive operations, such as interpretation, analysis, evaluation, inference, explanation and self-regulation. The authors of this book examine the theories, methods and challenges of critical thinking and its applications in the real world.