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A comprehensive and versatile treatment of an important and complex topic in vehicle design Written by an expert in the field with over 30 years of NVH experience, Noise and Vibration Control of Automotive Body offers nine informative chapters on all of the core knowledge required for noise, vibration, and harshness engineers to do their job properly. It starts with an introduction to noise and vibration problems; transfer of structuralΓÇôborne noise and airborne noise to interior body; key techniques for body noise and vibration control; and noise and vibration control during vehicle development. The book then goes on to cover all the noise and vibration issues relating to the automotive body, including: overall body structure; local body structure; sound package; excitations exerted on the body and transfer functions; wind noise; body sound quality; body squeak and rattle; and the vehicle development process for an automotive body. Vehicle noise and vibration is one of the most important attributes for modern vehicles, and it is extremely important to understand and solve NVH problems. Noise and Vibration Control of Automotive Body offers comprehensive coverage of automotive body noise and vibration analysis and control, making it an excellent guide for body design engineers and testing engineers. Covers all the noise and vibration issues relating to the automotive body Features a thorough set of tables, illustrations, photographs, and examples Introduces automotive body structure and noise and vibration problems Pulls together the diverse topics of body structure, sound package, sound quality, squeak and rattle, and target setting Noise and Vibration Control of Automotive Body is a valuable reference for engineers, designers, researchers, and graduate students in the fields of automotive body design and NVH.
Umfassende Einführung in die Modellierung der Geschwindigkeit enzymatischer Reaktionen unter Berücksichtigung der Wirkungen physikalisch-chemischer ParameterAnalysis of Enzyme Reaction Kinetics ist das zweite zweibändige Referenzwerk in einer einzigartigen 11-bändigen Sammlung zum Thema Enzymreaktor-Engineering. In dieser Publikation werden Geschwindigkeitsausdrücke für enzymatische Reaktionen unter Berücksichtigung der Modulation durch physikalisch-chemische Faktoren angegeben, und es werden Instrumente dargestellt, mit denen sich vorhersagen und kontrollieren lässt, wie schnell Substrate in Produkte umgesetzt werden. Band 1 enthält die von mechanistischen Postulaten mathematisch abgeleiteten Geschwindigkeitsausdrücke, ergänzt um geeignete statistische Verfahren für die Anpassung an Versuchsdaten. Band 2 behandelt die Wirkungen der physikalischen und chemischen Parameter auf die Geschwindigkeit von enzymkatalysierten und Enzymdeaktivierungs-Reaktionen.Analysis of Enzyme Reaction Kinetics in zwei Bänden ist ein umfassendes Referenzwerk für alle, die Enzymreaktionen erforschen oder in diesem Bereich arbeiten, sowie für Fachleute, die sich mit der Kontrolle von Reaktoren beschäftigen.
A comprehensive survey of advanced multilevel converter design, control, operation and gridΓÇôconnected applications Advanced Multilevel Converters and Applications in Grid Integration presents a comprehensive review of the core principles of advanced multilevel converters, which require fewer components and provide higher power conversion efficiency and output power quality. The authors ΓÇô noted experts in the field ΓÇô explain in detail the operation principles and control strategies and present the mathematical expressions and design procedures of their components. The text examines the advantages and disadvantages compared to the classical multilevel and two level power converters. The authors also include examples of the industrial applications of the advanced multilevel converters and offer thoughtful explanations on their control strategies. Advanced Multilevel Converters and Applications in Grid Integration provides a clear understanding of the gap difference between research conducted and the current industrial needs. This important guide: Puts the focus on the new challenges and topics in related areas such as modulation methods, harmonic analysis, voltage balancing and balanced current injection Makes a strong link between the fundamental concepts of power converters and advances multilevel converter topologies and examines their control strategies, together with practical engineering considerations Provides a valid reference for further developments in the multilevel converters design issue Contains simulations files for further study Written for university students in electrical engineering, researchers in areas of multilevel converters, highΓÇôpower converters and engineers and operators in power industry, Advanced Multilevel Converters and Applications in Grid Integration offers a comprehensive review of the core principles of advanced multilevel converters, with contributions from noted experts in the field.
A guide that explores what enables systems engineers to be effective in their profession and reveals how organizations can help them attain success The Paradoxical Mindset of Systems Engineers offers an inΓÇôdepth look at the proficiencies and personal qualities effective systems engineers require and the positions they should seek for successful careers. The book also gives employers practical strategies and tools to evaluate their systems engineers and advance them to higher performance. The authorsexplore why systems engineers are uncommon and how they can assess, improve, and cleverly leverage their uncommon strengths. These insights for being an ever more effective systems engineer apply equally well to classic engineers and project managers who secondarily do some systems engineering. The authors have written a guide to help systems engineers embrace the values that are most important to themselves and their organizations. Solidly based on interviews with over 350 systems engineers, classic engineers, and managers as well as detailed written career descriptions from 2500 systems engineers ΓÇö The Paradoxical Mindset of Systems Engineers identifies behavioral patterns that effective systems engineers use to achieve success. This important resource: Offers aspiring systems engineers practical methods for success that are built on extensive empirical evidence and underlying theory Shows systems engineers how to visually document their relative strengths and weaknesses, map out their careers, and compare themselves to the best in their organizations ΓÇô a rich set of tools for individuals, mentors, and organizations Offers practical guidance to managers and executives who lead systems engineering workforce improvement initiatives Written for systems engineers, their managers, business executives, those who do some systems engineering but primarily identify with other professions, as well as HR professionals, The Paradoxical Mindset of Systems Engineers offers the most comprehensive career guidance in the field available today.
The first book to be published on the Theta method, outlining under what conditions the method outperforms other forecasting methods This book is the first to detail the Theta method of forecasting ΓÇô one of the most difficultΓÇôtoΓÇôbeat forecasting benchmarks, which topped the biggest forecasting competition in the world in 2000: the M3 competition. Written by two of the leading experts in the forecasting field, it illuminates the exact replication of the method and under what conditions the method outperforms other forecasting methods. Recent developments such as multivariate models are also included, as are a series of practical applications in finance, economics, and healthcare. The book also offers practical tools in MS Excel and guidance, as well as provisional access, for the use of R source code and respective packages. Forecasting with the Theta Method: Theory and Applications includes three main parts. The first part, titled Theory, Methods, Models & Applications details the new theory about the method. The second part, Applications & Performance in Forecasting Competitions, describes empirical results and simulations on the method. The last part roadmaps future research and also include contributions from another leading scholar of the method ΓÇô Dr. Fotios Petropoulos. First ever book to be published on the Theta Method Explores new theory and exact conditions under which methods would outperform most forecasting benchmarks Clearly written with practical applications Employs R ΓÇô open source code with all included implementations Forecasting with the Theta Method: Theory and Applications is a valuable tool for both academics and practitioners involved in forecasting and respective software development.
Research in robust statistics is flourishing, and since the first edition of this book was published many important advances have been made in this area. However, there are relatively few books covering robust statistics, and even fewer that cover the subject in a comprehensive and definitive manner. This new edition will fulfill the need for a good upΓÇôtoΓÇôdate text that presents a broad overview of the theory of robust statistics, integrated with applications and computing. Updated to focus on the use of the popular software package R , it will feature inΓÇôdepth coverage of the key methodology, including regression, multivariate analysis, and time series. The book will be illustrated throughout by a range of examples and applications, and supported by a companion website featuring data sets and R code to allow the reader to reproduce the examples given in the book.
The 78th Glass Problem Conference (GPC) including the 11th Advances in Fusion and Processing of Glass (AFPG) Symposium is organized by the Kazuo Inamori School of Engineering, The New York State College of Ceramics, Alfred University, Alfred, NY 14802 and The Glass Manufacturing Industry Council (GMIC), Westerville, OH 43082. The Program Director was S. K. Sundaram, Inamori Professor of Materials Science and Engineering, Kazuo Inamori School of Engineering, The New York State College of Ceramics, Alfred University, Alfred, NY 14802. The Conference Director was Robert Weisenburger Lipetz, Executive Director, Glass Manufacturing Industry Council (GMIC), Westerville, OH 43082. Donna Banks of the GMIC coordinated the events and provided support. The Conference started with a half-day plenary session followed by technical sessions. The themes and chairs of four half-day technical sessions were as follows: Modeling, Sensors, and Furnace DesignJames Uhlik, Toledo Engineering Company, Inc., Toledo, OH and Michelle Korwin-Edson, Owen Corning Composite Solutions, Granville, OH Refractories & TestingLaura Lowe - North American Refractory Company, Pittsburgh, PA, Larry McCloskey - Anchor Acquisition, LLC, Lancaster, OH, and Laura Lowe - North American Refractory Company, Pittsburgh, PA and Larry McCloskey - Anchor Acquisition, LLC, Lancaster, OH CombustionGlenn Neff, Glass Service USA, Inc., Stuart, FL and Uyi Iyoha, Praxair Inc., Tonawanda, NY Environmental & SafetyPhil Tucker, Johns Manville, Denver, CO and Elmer Sperry, Libbey Glass, Toledo, OH
Electricity distribution is the penultimate stage in the delivery of electricity to end users. The only book that deals with the key topics of interest to distribution system engineers, Electric Distribution Systems presents a comprehensive treatment of the subject with an emphasis on both the practical and academic points of view.
Get familiar with business sustainability in AsiaBusiness Sustainability in Asia offers 12 chapters that cover different aspects of business sustainability with a keen focus on its implications in Asia. Anyone who is involved with business sustainability and corporate governance, the financial reporting process, investment decisions, legal and financial advising, assurance functions, and corporate governance education will be interested in this book.It examines business sustainability performance, reporting and assurance and their integration into strategy, governance, risk assessment, performance management, and the reporting process of disclosing governance, ethics, social, environmental, and economic sustainable performance. The book also highlights how people, businesses, and resources collaborate in a business sustainability and accountability model.* Develop an awareness and understanding of the main themes, perspectives, frameworks, and issues pertaining to corporate governance and business sustainability in Asia* Covers a variety of issues relevant to business sustainability in Asia* Authored by an expert who has written extensively on the subject* Understand why organizations worldwide recognize the importance of sustainability performanceIf you're a business leader, executive, auditor, or student looking to familiarize yourself with this emerging subject, Business Sustainability in Asia has you covered.
New modes of practice are now emerging in architecture. Rural Studio, Exyzt, Muf, Assemble and many more have led the way by challenging conventional ideas of 'The Architect' and reclaiming the notion of architecture as something public that should work ultimately towards the collective good. This quiet revolution is born out of a crisis in the profession and a wider vacuum in the political, environmental and economic situation. On the one hand, architecture as a profession has seen its influence diminish rapidly over the last 50 years through privatisation and the dominance of finance, while on the other hand it has also lacked collective courage and readiness to evolve. Without necessarily being aware of each other, studios around the world are now redefining the profession of architecture as something more proactive, self-aware and political. They are broadening their skill sets and becoming deeply involved in their projects, initiating them themselves, financing them and running them. Though much of this work is dealing with local issues at a relatively small scale, it is inherently ambitious with global application.* Contributors include: Shumi Bose, Indy Johar, Alison Killing, Douglas Murphy, and Finn Williams* Featured architects: Aterlier d'Architecture Autogérée (AAA), adamo-faiden; Baupiloten, Grupo Toma, Hector, Inteligencias Colectivas, raumlaborberlin, studioBASAR, Studio GutGut, Taller Ken, and We Made That.
A comprehensive resource to the origin, properties, and analysis of natural gas and its constituentsHandbook of Natural Gas Analysis is a comprehensive guide that includes information on the origin and analysis of natural gas, the standard test methods, and procedures that help with the predictability of gas composition and behavior during gas cleaning operations and use. The author--a noted expert on the topic--also explores the properties and behavior of the various components of natural gas and gas condensate.All chapters are written as stand-alone chapters and they cover a wealth of topics including history and uses; origin and production; composition and properties; recovery, storage, and transportation; properties and analysis of gas stream and gas condensate. The text is designed to help with the identification of quality criteria appropriate analysis and testing that fall under the umbrella of ASTM International. ASTM is an organization that is recognized globally across borders, disciplines and industries and works to improve performance in manufacturing and materials and products. This important guide:* Contains detailed information on natural gas and its constituents* Offers an analysis of methane, gas hydrates, ethane, propane, butane, and gas condensate* Includes information on the behavior of natural gas to aid in the planning for recovery, storage, transportation, and use* Covers the test methods that are applicable to natural gas and its constituents* Written in accessible and easy-to-understand termsWritten for scientists, engineers, analytical chemists who work with natural gas as well as other scientists and engineers in the industry, Handbook of Natural Gas Analysis offers a guide to the analysis, standard test methods, and procedures that aid in the predictability of gas composition and behavior during gas cleaning operations and use.
Systematically summarizes the current status and recent advances in bimetallic structures, their shapeΓÇôcontrolled synthesis, properties, and applications Intensive researches are currently being carried out on bimetallic nanostructures, focusing on a number of fundamental, physical, and chemical questions regarding their synthesis and properties. This book presents a systematic and comprehensive summary of the current status and recent advances in this field, supporting readers in the synthesis of model bimetallic nanoparticles, and the exploration and interpretation of their properties. Bimetallic Nanostructures: ShapeΓÇôControlled Synthesis for Catalysis, Plasmonics and Sensing Applications is divided into three parts. Part 1 introduces basic chemical and physical knowledge of bimetallic structures, including fundamentals, computational models, and in situ characterization techniques. Part 2 summarizes recent developments in synthetic methods, characterization, and properties of bimetallic structures from the perspective of morphology effect, including zeroΓÇôdimensional nanomaterials, oneΓÇôdimensional nanomaterials, and twoΓÇôdimensional nanomaterials. Part 3 discusses applications in electrocatalysis, heterogeneous catalysis, plasmonics and sensing. Comprehensive reference for an important multidisciplinary research field Thoroughly summarizes the present state and latest developments in bimetallic structures Helps researchers find optimal synthetic methods and explore new phenomena in surface science and synthetic chemistry of bimetallic nanostructures Bimetallic Nanostructures: ShapeΓÇôControlled Synthesis for Catalysis, Plasmonics and Sensing Applications is an excellent source or reference for researchers and advanced students. Academic researchers in nanoscience, nanocatalysis, and surface plasmonics, and those working in industry in areas involving nanotechnology, catalysis and optoelectronics, will find this book of interest.
Summarizes and surveys current LTE technical specifications and implementation options for engineers and newly qualified support staffConcentrating on three mobile communication technologies, GSM, 3G-WCDMA, and LTE--while majorly focusing on Radio Access Network (RAN) technology--this book describes principles of mobile radio technologies that are used in mobile phones and service providers' infrastructure supporting their operation. It introduces some basic concepts of mobile network engineering used in design and rollout of the mobile network. It then follows up with principles, design constraints, and more advanced insights into radio interface protocol stack, operation, and dimensioning for three major mobile network technologies: Global System Mobile (GSM) and third (3G) and fourth generation (4G) mobile technologies. The concluding sections of the book are concerned with further developments toward next generation of mobile network (5G). Those include some of the major features of 5G such as a New Radio, NG-RAN distributed architecture, and network slicing. The last section describes some key concepts that may bring significant enhancements in future technology and services experienced by customers.Introduction to Mobile Network Engineering: GSM, 3G-WCDMA, LTE and the Road to 5G covers the types of Mobile Network by Multiple Access Scheme; the cellular system; radio propagation; mobile radio channel; radio network planning; EGPRS - GPRS/EDGE; Third Generation Network (3G), UMTS; High Speed Packet data access (HSPA); 4G-Long Term Evolution (LTE) system; LTE-A; and Release 15 for 5G.* Focuses on Radio Access Network technologies which empower communications in current and emerging mobile network systems* Presents a mix of introductory and advanced reading, with a generalist view on current mobile network technologies* Written at a level that enables readers to understand principles of radio network deployment and operation* Based on the author's post-graduate lecture course on Wireless Engineering* Fully illustrated with tables, figures, photographs, working examples with problems and solutions, and section summaries highlighting the key features of each technology describedWritten as a modified and expanded set of lectures on wireless engineering taught by the author, Introduction to Mobile Network Engineering: GSM, 3G-WCDMA, LTE and the Road to 5G is an ideal text for post-graduate and graduate students studying wireless engineering, and industry professionals requiring an introduction or refresher to existing technologies.
Moran's Principles of Engineering Thermodynamics, SI Version, continues to offer a comprehensive and rigorous treatment of classical thermodynamics, while retaining an engineering perspective. With concise, applications-oriented discussion of topics and self-test problems, this book encourages students to monitor their own learning. This classic text provides a solid foundation for subsequent studies in fields such as fluid mechanics, heat transfer and statistical thermodynamics, and prepares students to effectively apply thermodynamics in the practice of engineering. This edition is revised with additional examples and end-of-chapter problems to increase student comprehension.
The updated third edition of the definitive text on health social work Thoroughly revised and updated, the third edition of Handbook of Health Social Work is an authoritative text that offers a comprehensive review of the diverse field of health social work. With contributions from a panel of international experts in the field, the book is theory driven and solidly grounded in evidence-based practice. The contributors explore both the foundation of social work practice and offer guidance on effective strategies, policies, and program development. The text provides information that is essential to the operations of social workers in health care including the conceptual underpinnings and the development of the profession. The authors explore practice issues such as theories of health behavior, assessment, communication and the intersections between health and mental health. The authors also examine a wide range of examples of social work practices including settings that involve older adults, nephrology, oncology, and chronic diseases such as diabetes, heart disease, HIV/AIDS, genetics, end of life care, pain management and palliative care, as well as alternative treatments, and traditional healers. This is the only handbook of its kind that unites the body of health social work and: Offers a wellness, rather than psychopathological perspective and contains treatment models that are evidence-based Includes learning exercises, further resources, research suggestions, and life-course information Contains new chapters on topics such as international health, insurance and payment systems, and implementation of evidence-based practice Presents information on emerging topics such as health policy in an age of reform, and genomics and the social environment Reviews new trends in social work and health care including genetics, trans-disciplinary care, and international, national, and state changes in policy Written for social work educators, administrators, students, and practitioners, the revised third edition of Handbook of Health Social Work offers in one volume the entire body of health social work knowledge.
Climate change is one of the most controversial and argued issues in the world today, and it has been for years. It has been politicized by politicians on all sides, some scientists have used the study of it for their own material gain above true scientific discovery, and some scientific theories surrounding it have been believed even though proven false. But there is not, by any means, complete agreement among all scientists throughout the world on this issue.Written by two of the world's most well-respected environmental and petroleum engineers, this book is meant to be one voice in the scientific literature on this important subject. Other books, also available from Wiley-Scrivener, take the opposite stance, but it is important, in our scientific journey, to listen to all voices and rely on facts, rather than opinions. We trust the reader to make his or her decisions based on all of the facts, and not just some of them.
The 97th volume in this series for organic chemists in industry presents critical discussions of widely used organic reactions or particular phases of a reaction. The material is treated from a preparative viewpoint, with emphasis on limitations, interfering influences, effects of structure and the selection of experimental techniques. The work includes tables that contain all possible examples of the reaction under consideration. Detailed procedures illustrate the significant modifications of each method.
"Healthcare markets are in need of redesign. This timely Handbook showcases what analytics have to offer." --Alvin E. Roth, Nobel Laureate in Economics Craig and Susan McCaw Professor of Economics at Stanford University How can analytics scholars and healthcare professionals access the most exciting and important healthcare topics and tools for the 21st century? Editors Tinglong Dai and Sridhar Tayur, aided by a team of internationally acclaimed experts, have curated this timely volume to help newcomers and seasoned researchers alike to rapidly comprehend a diverse set of thrusts and tools in this rapidly growing cross-disciplinary field. The Handbook covers a wide range of macro-, meso- and micro-level thrusts--such as market design, competing interests, global health, personalized medicine, residential care and concierge medicine, among others--and structures what has been a highly fragmented research area into a coherent scientific discipline. The handbook also provides an easy-to-comprehend introduction to five essential research tools--Markov decision process, game theory and information economics, queueing games, econometric methods, and data science--by illustrating their uses and applicability on examples from diverse healthcare settings, thus connecting tools with thrusts. The primary audience of the Handbook includes analytics scholars interested in healthcare and healthcare practitioners interested in analytics. This Handbook: Instills analytics scholars with a way of thinking that incorporates behavioral, incentive, and policy considerations in various healthcare settings. This change in perspective--a shift in gaze away from narrow, local and one-off operational improvement efforts that do not replicate, scale or remain sustainable--can lead to new knowledge and innovative solutions that society has been seeking so desperately. Facilitates collaboration between healthcare experts and analytics scholar to frame and tackle their pressing concerns through appropriate modern mathematical tools designed for this very purpose. The handbook is designed to be accessible to the independent reader, and it may be used in a variety of settings, from a short lecture series on specific topics to a semester-long course.
A comprehensive guide to understanding, assessing, and responding to terrorism in this modern age This book provides readers with a thorough understanding of the types of attacks that may be perpetrated, and how to identify potential targets, conduct a meaningful vulnerability analysis, and apply protective measures to secure personnel and facilities. The new edition of Understanding, Assessing, and Responding to Terrorism updates existing material and includes several new topics that have emerged, including information on new international terrorist groups as well as a new chapter on Regulations and Standards. A vulnerability analysis methodology, consisting of several steps—which include the techniques necessary to conduct a vulnerability analysis—is introduced and applied through several sample scenarios. By using easily customized templates for the screening process, valuation of a critical asset as a target, vulnerability analysis, security procedures, emergency response procedures, and training programs, the book offers a practical step–by–step process to help reduce risk. Each different type of terrorism is briefly discussed—however, the book focuses on those potential attacks that may involve weapons of mass destruction. There is a discussion of what physical and administrative enhancements can be implemented to improve a facility′s ability to devalue, detect, deter, deny, delay, defend, respond, and recover to a real or threatened terrorist attack—whether it be at a facility, or in the community. Techniques on how personnel safety and security can be improved through the implementation of counter–terrorism programs are also outlined. An overview of the major counter–terrorism regulations and standards are presented, along with the significant governmental efforts that have been implemented to help prevent terrorist attacks and foster preparedness at both private and public sector facilities and for personnel. Understanding, Assessing, and Responding to Terrorism, Second Edition: Updates existing material, plus includes several new topics that have emerged including information on new international terrorist groups, new terrorist tactics, cyber terrorism, and Regulations and Standards Outlines techniques for improving facility and personnel safety and security through the implementation of counter–terrorism programs Unites the emergency response/public sector community with the private sector over infrastructure protection, thus allowing for easier communication between them Includes questions/exercises at the end of each chapter and a solutions manual to facilitate its use as a textbook Understanding, Assessing, and Responding to Terrorism, Second Edition is a must–have reference for private and public sector risk managers, safety engineers, security professionals, facility managers, emergency responders, and others charged with protecting facilities and personnel from all types of hazards (accidental, intentional, and natural).
"I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better."Farah Magrabi, Macquarie University, Australia"The reader will find intriguing not only the title but also the content of the book. I'm also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion."Elena Andresen, Oregon Health & Science University, USA"This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally."Gerald Pepe, Eastern Virginia Medical School, USA"This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts."Zoltán Néda, Babe_-Bolyai University, Romania"I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature."David Fleming, University of Missouri, USAA comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovationThis vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers.The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource:* Highlights the research phase from design to discovery that precedes innovation disclosure* Offers a step by step explanation of how to improve innovation* Offers solutions for improving research and innovation productivity in the life sciences* Contains a variety of statistical databases and a vast number of stories about individual discoveries* Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutionsWritten for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading to biomedical innovation and identifies the best practices of innovative scientists and laboratories.
Wichtiges Referenzwerk zu organischen Kristallen in der Arzneimittelentwicklung.Da es sich bei der Mehrheit der pharmazeutischen Festkörperstoffe um organische Kristalle handelt, sind der Umgang mit und die Verarbeitung von diesen Stoffen kritische Aspekte bei der Arzneimittelentwicklung. Pharmaceutical Crystals: Science and Engineering führt in die Welt der organischen Kristalle ein und untersucht deren wichtige Rolle bei der Entwicklung und Herstellung von Medikamenten. Die Inhalte stammen von führenden Forscher und Fachexperten, die Grundlagenwissen vermitteln und die Verbindung zwischen pharmazeutisch relevanten Eigenschaften und der Struktur von Kristallen herstellen.Das Werk ist ausführlich und behandelt eine Vielzahl von Themen, z. B.: Kristallisation, molekulare Wechselwirkungen, Polymorphismus, analytische Methoden, Verarbeitung und chemische Stabilität. Die Autoren zeigen, wie man Lösungen für die Auswahl von pharmazeutischen Formen und Kristallisationsprozesse findet. Das Fachbuch ist eine unschätzbare Hilfe zur Verbesserung des Entwicklungsprozesses von kleinen Wirkstoffmolekülen.- Bietet einen Überblick über die wichtigsten Aspekte der Festkörperchemie und deren Rolle bei der Wirkstoffentwicklung.- Stellt Lösungen für die Auswahl von pharmazeutischen Formen und Kristallisationsprozesse vor.- Ausgewogen Darstellung - wissenschaftliche Grundlagen und pharmazeutische Anwendungen.- Behandelt die Kristallographie, molekulare Wechselwirkungen, Polymorphismus, Analysemethoden, Verarbeitung und chemische Stabilität.
Real-world tools to build your venture, grow your business, and avoid mistakesStartup, Scaleup, Screwup is an expert guide for emerging and established businesses to accelerate growth, facilitate scalability, and keep pace with the rapidly changing economic landscape. The contemporary marketplace is more dynamic than ever before--increased global competition, the impact of digital transformation, and disruptive innovation factors require businesses to implement agile management and business strategies to compete and thrive. This indispensable book provides business leaders and entrepreneurs the tools and guidance to meet growth and scalability challenges head on.Equal parts motivation and practical application, this book answers the questions every business leader asks from the startup ventures to established companies. Covering topics including funding options, employee hiring, product-market validation, remote team management, agile scaling, and the business lifecycle, this essential resource provides a solid approach to grow at the right pace and stay lean. This book will enable you to:* Apply 42 effective tools to sustain and accelerate your business growth* Avoid the mistakes and pitfalls associated with rapid business growth or organizational change* Develop a clear growth plan to integrate into your overall business model* Structure your business for rapid scaling and efficient managementStartup, Scaleup, Screwup: 42 Tools to Accelerate Lean & Agile Business Growth is a must-read for entrepreneurs, founders, managers, and senior executives. Author Jurgen Appelo shares his wisdom on the creative economy, agile management, innovation marketing, and organizational change to provide a comprehensive guide to business growth. Practical methods and expert advice make this book an essential addition to any business professional's library.
Raman spectroscopy is an analytical technique used for solving problems in a wide variety of applications. This book provides detailed information and worked examples on how to carry out Raman experiments and interpret Raman spectra. The author also covers Resonance Raman and SERS, which are two emerging areas of Raman.
Thorough Overview Identifies and Addresses Critical Gaps in the Treatment of Several Chronic Diseases With increasing numbers of patients suffering from Immune-Mediated Inflammatory Diseases (IMIDs), and with the increasing reliance on biopharmaceuticals to treat them, it is imperative that researchers and medical practitioners have a thorough understanding of the absorption, distribution, metabolism and excretion (ADME) of therapeutic proteins as well as translational pharmacokinetic/pharmacodynamic (PK/PD) modeling for them. This comprehensive volume answers that need to be addressed. Featuring eighteen chapters from world-renowned experts and opinion leaders in pharmacology, translational medicine and immunology, editors Honghui Zhou and Diane R. Mould have curated a much-needed collection of research on the advanced applications of pharmacometrics and systems pharmacology to the development of biotherapeutics and individualized treatment strategies for the treatment of IMIDs. Authors discuss the pathophysiology of autoimmune diseases in addition to both theoretical and practical aspects of quantitative pharmacology for therapeutic proteins, current translational medicine research methodologies and novel thinking in treatment paradigm strategies for IMIDs. Other notable features include: Contributions from well-known authors representing leading academic research centers, specialized contract research organizations and pharmaceutical industries whose pipelines include therapeutic proteins Chapters on a wide range of topics (e.g., pathophysiology of autoimmune diseases, biomarkers in ulcerative colitis, model-based meta-analysis use in the development of therapeutic proteins) Case studies of applying quantitative pharmacology approaches to guiding therapeutic protein drug development in IMIDs such as psoriasis, inflammatory bowel disease, multiple sclerosis, and lupus Zhou and Mould's timely contribution to the critical study of biopharmaceuticals is a valuable resource for any academic and industry researcher working in pharmacokinetics, pharmacology, biochemistry, or biotechnology as well as the many clinicians seeking the safest and most effective treatments for patients dealing with chronic immune disorders.
Develop the skillset essential to successful securitisation swaps managementSecuritisation Swaps is a complete practitioner's guide to this unique and complex class of derivatives. This detailed examination follows the entire life cycle of securitisation swaps to give quants, structurers, traders, originators, issuers and lawyers a common reference for understanding their shared objective. Broad in scope to provide a common-ground perspective -- yet detailed enough to promote full understanding -- the discussion takes a distinctly cross-disciplinary approach that encompasses the multi-faceted knowledge base required to successfully execute these complex trades.Despite the fact that the size of the market is trillions of dollars in notional principal, securitisation swaps have thus far been neglected in both academic and practitioner literature. The numerous stakeholders that work together on these complex deals will all greatly benefit from a thorough understanding of their underlying risks and gain deep insight into the perspectives of each stakeholder. This invaluable guide provides multi-disciplinary insight that allows practitioners to:* Manage securitisation swaps more effectively, from pre-trade structuring and modelling to post-trade risk management and accounting* Understand the elements of securitisation and covered bonds, and how swaps mitigate risk in these types of transactions* Explore how securitisation swaps differ from other derivatives and delve into their three specific risk factors -- swap prepayment risk, swap extension risk and downgrade risk* Learn practical methods and strategies of risk management, accounting, pricing and transaction executionWhen securitisation trades go wrong, they become front-page news -- but when each participant understands accurate modelling, risk mitigation, optimal structuring, costs, pricing, commercial backgrounds and other integral practices, they are able to work together to achieve a shared objective. Securitisation Swaps provides the essential knowledge that streamlines and safeguards these important trades.
The third medical atlas in this new series on the human body and filled with detailed pictures, this atlas details the topographical and pathotopographical anatomy of the chest, abdomen, lumbar region, and retroperitoneal space, a useful reference for medical professionals and students alike. Written by an experienced and well-respected physician and professor, this new volume, building on the previous volume, Ultrasonic Topographical and Pathotopographical Anatomy, and its sequel, Topographical and Pathotopographical Medical Atlas of the Head and Neck, also available from Wiley-Scrivener, presents the ultrasonic topographical and pathotopographical anatomy of the chest, abdomen, lumbar region, and retroperitoneal space, offering further detail into these important areas for use by medical professionals. This series of atlases of topographic and pathotopographic human anatomy is a fundamental and practically important series designed for doctors of all specializations and students of medical schools. Here you can find almost everything that is connected with the topographic and pathotopographic human anatomy, including original graphs of logical structures of topographic anatomy and development of congenital abnormalities, topography of different areas in layers, pathotopography, and computer and magnetic resonance imaging (MRI) of topographic and pathotopographic anatomy. Also you can find here new theoretical and practical sections of topographic anatomy developed by the author himself which are published for the first time. They are practically important for mastering the technique of operative interventions and denying the possibility of iatrogenic complications during operations. This important new volume will be valuable to physicians, junior physicians, medical residents, lecturers in medicine, and medical students alike, either as a textbook or as a reference. It is a must-have for any physician's library. This groundbreaking new volume: Using the same technology as the first two atlases by the same author, solves the problem of visualization of topographical and pathotopographical anatomy Builds on the author's previous book, Ultrasonic Topographical and Pathotopographical Anatomy and the sequel, focusing solely on the areas of the chest, abdomen, and surrounding regions Goes beyond previous attempts, which are often drawings, by using state-of-the-art technology to show detailed physiological areas Is for medical professionals of all types and levels, from students and professors to working doctors and other medical professionals doing research and development AUDIENCE: Physicians, interns, junior physicians, medical residents, medical students, specialists in surgery, traumatology, neurosurgery, oncology, urology, obstetrics and gynecology, dental surgery, anesthesiology, and other medical specialists concerned with different topographical and anatomical structures.
Get on the right college path with the next-generation ACCUPLACERThe next-generation ACCUPLACER is a compilation of computerized assessments that's designed to evaluate a student's skills in reading, writing, mathematics, and computer abilities. Next-generation ACCUPLACER determines how prepared students are for college courses, and places them in the appropriate course level where they will best succeed and grow as a learner.Next-Generation ACCUPLACER For Dummies with Online Practice is the one-stop guide for students who want to get a head start on scoring well on the important college placement tests for reading, writing, and math. With tips, tricks, and plenty of practice questions in the book, plus two full-length practice tests online, it helps you know what to expect and perform your absolute best on test day.* Identify knowledge gaps and areas of strength* Find skill-building support with tools that improve your readiness for college* Get placed into the right college course* Discover preparation tactics and opportunities for individual successIf you're looking for a one-stop resource for preparing for the next-generation ACCUPLACER, the book starts here!
The bestselling beginner's guide to Microsoft WordWhether you've used older versions of this popular program or have never processed a single word, this hands-on guide gets you going with the latest version of Microsoft Word. In no time, you'll begin editing, formatting, proofing, and dressing up your Word documents like a pro.In this leading book about the world's number one word processing application, Dan Gookin talks about using Microsoft Word in friendly, easy-to-follow terms. Focusing on the needs of the beginning Word user, it provides everything you need to know about Word--without any painful jargon.* Covers the new and improved features found in the latest version of Word* Create your own templates* Explains why you can't always trust the spell checker* Offers little-known keyboard shortcutsIf you're new to Word and want to spend more time on your actual work rather than figuring out how to make it work for you, this new edition of Word X For Dummies has you covered.
Now updated and revised to cover the latest features of Microsoft Office 2019The world's leading suite of business productivity software, Microsoft Office helps users complete common business tasks, including word processing, email, presentations, data management and analysis, and much more. Whether you need accessible instruction on Word, Excel, PowerPoint, Outlook, or Access--or all of the above--this handy reference makes it easier.In Office X For Dummies, you'll get help with typing and formatting text in Word, creating and navigating an Excel spreadsheet, creating a powerful PowerPoint presentation, adding color, pictures, and sound to a presentation, configuring email with Outlook, designing an Access database, and more. Information is presented in the straightforward but fun language that has defined the Dummies series for more than twenty years.* Get insight into common tasks and advanced tools* Find full coverage of each application in the suite* Benefit from updated information based on the newest software release* Make your work life easier and more efficientlyIf you need to make sense of Office X and don't have time to waste, this is the trusted reference you'll want to keep close at hand!
One book that does the work of nineKnowing your way around Microsoft Office requires you to be part mathematician, part storyteller, and part graphic designer--with some scheduling wizard and database architect sprinkled in. So what do you do if these talents don't come naturally to you?Fear not! Office 2019 All-in-One For Dummies fills in the gaps and helps you create easy-to-read Word documents, smash numbers in Excel, tell your tale with PowerPoint, and keep it all organized with Outlook. With additional books covering Access, OneNote, and common Office tasks, this is the only Office book you need on your shelf.* Get insight into tools common to all Office applications* Find full coverage of Word, Excel, PowerPoint, Outlook, and Access* Benefit from updated information based on the newest software release* Discover the tricks Office pros use to enhance efficiencyIf you need to make sense of Office 2019and don't have time to waste, this is the all-in-one reference you'll want to keep close by!
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