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Die 3. englische Auflage von The Handbook of Enology ist eine überarbeitete Übersetzung der 9. französischen Auflage aus dem Jahr 2017. Das zweibändige Referenzwerk beschreibt alle Aspekte der Weinherstellung, detailliert und aus wissenschaftlicher Sicht. Die Autoren, hoch angesehene Önologen, untersuchen die Prozesse der Weinherstellung und entwickeln eine Theorie des perfekten Verfahrens, das die notwendigen Komponenten richtig kombiniert, um einen Qualitätsjahrgang herzustellen. Sie betrachten auch häufige Probleme und zeigen, was hinter den Problemen steckt, um eine Diagnose zu stellen und Lösungen zu ermöglichen.

A complete textbook and reference for engineers to learn the fundamentals of computer programming with modern C++Introduction to Programming with C++ for Engineers is an original presentation teaching the fundamentals of computer programming and modern C++ to engineers and engineering students.Professor Cyganek, a highly regarded expert in his field, walks users through basics of data structures and algorithms with the help of a core subset of C++ and the Standard Library, progressing to the object-oriented domain and advanced C++ features, computer arithmetic, memory management and essentials of parallel programming, showing with real world examples how to complete tasks. He also guides users through the software development process, good programming practices, not shunning from explaining low-level features and the programming tools.Being a textbook, with the summarizing tables and diagrams the book becomes a highly useful reference for C++ programmers at all levels.Introduction to Programming with C++ for Engineers teaches how to program by:* Guiding users from simple techniques with modern C++ and the Standard Library, to more advanced object-oriented design methods and language features* Providing meaningful examples that facilitate understanding of the programming techniques and the C++ language constructions* Fostering good programming practices which create better professional programmers* Minimizing text descriptions, opting instead for comprehensive figures, tables, diagrams, and other explanatory material* Granting access to a complementary website that contains example code and useful links to resources that further improve the reader's coding ability* Including test and exam question for the reader's review at the end of each chapterEngineering students, students of other sciences who rely on computer programming, and professionals in various fields will find this book invaluable when learning to program with C++.

This book covers the area of tribology broadly, providing important introductory chapters to fundamentals, processing, and applications of tribology. The book is designed primarily for easy and cohesive understanding for students and practicing scientists pursuing the area of tribology with focus on materials. This book helps students and practicing scientists alike understand that a comprehensive knowledge about the friction and wear properties of advanced materials is essential to further design and development of new materials.The description of the wear micromechanisms of various materials will provide a strong background to the readers as how to design and develop new tribological materials. This book also places importance on the development of new ceramic composites in the context of tribological applications.Some of the key features of the book include: Fundamentals section highlights the salient issues of ceramic processing and mechanical properties of important oxide and non-oxide ceramic systems; State of the art research findings on important ceramic composites are included and an understanding on the behavior of silicon carbide (SiC) based ceramic composites in dry sliding wear conditions is presented as a case study; Erosion wear behavior of ceramics, in which case studies on high temperature erosion behavior of SiC based composites and zirconium diboride (ZrB2) based composites is also covered; Wear behavior of ceramic coatings is rarely discussed in any tribology related books therefore a case study explaining the abrasion wear behavior of WC-Co coating is provided. Finally an appendix chapter is included in which a collection of several types of questions including multiple choice, short answer and long answer are provided.

Master new, disruptive technologies in the field of auditingAgile Auditing: Fundamentals and Applications introduces readers to the applications and techniques unlocked by tested and proven agile project management principles. This book educates readers on an approach to auditing that emphasizes risk-based auditing, collaboration, and speedy delivery of meaningful assurance assessments while ensuring quality results and a focus on the areas that pose the greatest material risks to the business under audit.The discipline of auditing has been forever changed via the introduction of new technologies, including:* Machine learning* Virtual Conferencing* Process automation* Data analyticsHugely popular in software development, the agile approach is just making its way into the field of audit. This book provides concrete examples and practical solutions for auditors who seek to implement agile techniques and methods.Agile Auditing is perfect for educators, practitioners, and students in the auditing field who are looking for ways to introduce greater levels of efficiency and effectiveness to their discipline.

This book is intended for academic and industrial developers, exploring and developing applications in the area of big data and machine learning, including those that are solving technology requirements, evaluation of methodology advances and algorithm demonstrations.The intent of this book is to provide awareness of algorithms used for machine learning and big data in the academic and professional community. The 17 chapters are divided into 5 sections: Theoretical Fundamentals; Big Data and Pattern Recognition; Machine Learning: Algorithms & Applications; Machine Learning's Next Frontier and Hands-On and Case Study. While it dwells on the foundations of machine learning and big data as a part of analytics, it also focuses on contemporary topics for research and development. In this regard, the book covers machine learning algorithms and their modern applications in developing automated systems.Subjects covered in detail include:* Mathematical foundations of machine learning with various examples.* An empirical study of supervised learning algorithms like Naïve Bayes, KNN and semi-supervised learning algorithms viz. S3VM, Graph-Based, Multiview.* Precise study on unsupervised learning algorithms like GMM, K-mean clustering, Dritchlet process mixture model, X-means and Reinforcement learning algorithm with Q learning, R learning, TD learning, SARSA Learning, and so forth.* Hands-on machine leaning open source tools viz. Apache Mahout, H2O.* Case studies for readers to analyze the prescribed cases and present their solutions or interpretations with intrusion detection in MANETS using machine learning.* Showcase on novel user-cases: Implications of Electronic Governance as well as Pragmatic Study of BD/ML technologies for agriculture, healthcare, social media, industry, banking, insurance and so on.

Patty's Industrial Hygiene has had a reputation for the past 70 years of providing up to date information for the experienced as well as novice industrial hygienist.The field of IH continues to evolve with personnel working for multinational firms, small consulting firms, or self-employed. Currently, industrial hygienists not only have to worry about occupational health and safety concerns of global workforce which is more diverse, they often provide environmental health information for large companies, as well as large and small government agencies.In response to these changes, the 7th edition of Patty's Industrial Hygiene has added new industrial hygiene/safety topics and updated existing ones. This new edition addresses the needs brought about by globalization and the need for many professionals to expand their roles. This 7th Edition used reviewers from different regions of the world to ensure accuracy, comprehension and completeness of the topics covered by the worldwide contributors, and to cover topics of interest globally. Some of these new topics include robotics, sensors, health and safety issues related to new energy technologies, construction, and cannabis.

The Taxable Investor's Manifesto: Wealth Management Strategies to Last a Lifetime is written for every investor with taxable wealth and every advisor who serves them. The Taxable Investor's Manifesto guides readers through a series of related topics, bringing clarity to complexity with an economy of words, while providing valuable and actionable advice at every turn.This remarkable book combines the deep industry knowledge of a seasoned practitioner with the communication skills of a leading educator. Author Stuart E. Lucas is the founder and Chief Investment Officer of Wealth Strategist Partners, a firm that advises complex family enterprises, including his own. He also co-founded the University of Chicago's Private Wealth Management program, now in its fourteenth year.Most investment books only address pre-tax headline returns, but individuals pay taxes. The incentives and disincentives of our tax system can have a dramatic impact on actual investment time horizons and returns. The Manifesto sensibly folds tax incentives into investment strategy in ways that can add profound value over a lifetime to actual results. It includes guidance on:* How to keep a greater percentage of your profits with a higher probability of success and less effort* Why it's important to manage the intersection of investment, tax and estate planning* How to compete for better long-term investment returns against tax-exempt investors.Whether you're a young professional or entrepreneur, a mid-career manager, a senior business executive, or a retiree this book will give you tools to enhance your net worth considerably. If you are an advisor, studying and implementing Lucas's advice will strengthen your business and make your clients happier.

A comprehensive guide to the concepts and applications of queuing theory and traffic theoryNetwork Traffic Engineering: Models and Applications provides an advanced level queuing theory guide for students with a strong mathematical background who are interested in analytic modeling and performance assessment of communication networks.The text begins with the basics of queueing theory before moving on to more advanced levels. The topics covered in the book are derived from the most cutting-edge research, project development, teaching activity, and discussions on the subject. They include applications of queuing and traffic theory in:* LTE networks* Wi-Fi networks* Ad-hoc networks* Automated vehicles* Congestion control on the InternetThe distinguished author seeks to show how insight into practical and real-world problems can be gained by means of quantitative modeling. Perfect for graduate students of computer engineering, computer science, telecommunication engineering, and electrical engineering, Network Traffic Engineering offers a supremely practical approach to a rapidly developing field of study and industry.

Presents the components, challenges, and solutions of wireless automation as enablers for industry 4.0This timely book introduces the state of the art in industrial automation techniques, concentrating on wireless methods for a variety of applications, ranging from simple smart homes to heavy-duty complex industrial setting with robotics accessibility. It covers a wide range of topics including the industrial revolution enablers, applications, challenges, their possible solutions, and future directions.Wireless Automation as an Enabler for the Next Industrial Revolution opens with an introduction to wireless sensor networks and their applications in various domains, emphasizing industrial wireless networks and their future uses. It then takes a look at life-span extension for sensor networks in the industry, followed by a chapter on multiple access and resource sharing for low latency critical industrial networks. Industrial automation is covered next, as is the subject of ultra reliable low latency communications. Other topics include: self healing in wireless networks; cost efficiency optimization for industrial automation; a non event-based approach for non-intrusive load monitoring; wireless networked control; and caching at the edge in low latency wireless networks. The book finishes with a chapter on the application of terahertz sensing at nano-scale for precision agriculture.* Introduces the future evolving dimension in industrial automation and discusses the enablers of the industrial revolution* Places particular emphasis on wireless communication techniques which make industrial automation reliable, efficient, and cost-effective* Covers many of the associated topics and concepts like robotics, AI, internet-of-things, telesurgery, and remote manufacturing* Of great interest to researchers from academia and industry who are looking at the industrial development from various perspectivesWireless Automation as an Enabler for the Next Industrial Revolution is an excellent book for telecom engineers, IoT experts, and industry professionals. It would also greatly benefit researchers, professors, and doctorate and postgraduate students involved in automation and industry 4.0.

Provides clear and comprehensive coverage of recently developed applied biocatalysis for synthetic organic chemists with an emphasis to promote green chemistry in pharmaceutical and process chemistryThis book aims to make biocatalysis more accessible to both academic and industrial synthetic organic chemists. It focuses on current topics within the applied industrial biocatalysis field and includes short but detailed experimental methods on timely novel biocatalytic transformations using new enzymes or new methodologies using known enzymes. The book also features reactions that are "expanding and making the enzyme toolbox available to chemists"--providing readers with comprehensive methodology and detailed key sourcing information of a wide range of enzymes.Chapters in Applied Biocatalysis: The Chemist's Enzyme Toolkit are organized by reaction type and feature a short introductory section describing the current state of the art for each example. Much of the book focuses on processes for which the enzymes are readily available so that organic chemists can synthesize appropriate quantities of chemicals with available materials in a standard chemical laboratory. Advanced methods are included to present examples of new enzymes that might encourage collaboration with suppliers or academic groups and that will educate chemists of rapidly expanding future possibilities.* Focuses on current topics within the applied industrial biocatalysis field* Offers experimental methods on novel biocatalytic transformations using new enzymes or new methodology using known enzymes* Covers the hot topics of enzyme and chemoenzymatic cascades and biocatalysis in flow* Edited by noted experts from both academia and industry with years of experience in the field of biocatalysis--particularly, the industrial applications of enzymesWritten for synthetic organic chemists working in all industries but especially the pharmaceutical industry and for those in academia with an eye for biocatalysis, Applied Biocatalysis: The Chemist's Enzyme Toolkit will also benefit academic groups in chemistry and related sciences that are using enzymes for synthetic purposes, as well as those working in the area of enzymology and molecular biology.

A practical approach to environmental chemistry, Elements of Environmental Chemistry, 3rd Edition provides readers with the fundamentals of environmental chemistry and a toolbox for putting them into practice. This is a concise, accessible, and hands-on volume designed for students and professionals working in the chemical and environmental sciences.The 3rd Edition has been completely revised and rearranged. The first chapter on tool skills has been expanded to include thermodynamic considerations and measurement issues. The former chapter on the partitioning of organic compounds has been expanded to cover the fates of organic compounds, with an emphasis on developing the reader?s ?chemical intuition? for predicting a chemical?s fate based on structure. The material on lead, mercury, pesticides, PCBs, dioxins, and flame retardants has been expanded and combined into the last chapter and supplemented with more references to the literature. The problem sets have been extended and now include over 130 problems, some of which can be solved using Excel.

Great relationships don't happen by accident- they take commitment, hard work, and GRIT"You may already know I'm a raving fan of Jon Gordon-and when you add his wonderful wife, Kathryn, you'll see that one plus one is greater than two. In Relationship GRIT, the Gordons hold a lively back-and-forth discussion about the ups and downs of marriage and how to hang in there. Read this book with your significant other and move toward a positive future together."-KEN BLANCHARD, coauthor of The New One Minute Manager(r) and Servant Leadership in ActionRelationships-particularly marriages-are about imperfect people coming together to work on their individual flaws and emerging stronger together. Relationship GRIT will inspire and motivate you to engage in this remarkable and rewarding process. Find the strength you need to confront your past, overcome your flaws, and change for the better to improve you and your relationship.

Bietet erstmals eine umfassende Übersicht über alle Aspekte von auf Pyrrolidon und Caprolactam basierenden Materialien.Das umfassende sechsbändige Werk beschreibt das breite technische Universum der Gamma- und Epsilon-Lactame. Dabei wird die Chemie der kleinen, auf Lactam basierenden Moleküle eingehend untersucht, ihre einzigartigen Eigenschaften werden dargestellt und es wird gezeigt, wie sie eine große Zahl wirtschaftlich wichtiger Anwendungen ermöglicht haben. Von der Synthese über die Produktion bis zur Anwendung werden in diesem umfangreichen Werk die wesentlichen und aktuellen Entwicklungen im Bereich der Gamma- und Epsilon-Lactam-Forschung und -Technologie aufgezeigt und alle wesentlichen Aspekte der auf Pyrrolidon und Caprolactam basierenden Materialien dargestellt, wodurch die Leser einen gründlichen Überblick über das gesamte Fachgebiet erhalten.Das Handbook of Pyrrolidone and Caprolactam Based Materials: Synthesis, Characterization and Industrial Applications stellt in detaillierter und moderner Form dar, welchen Einfluss auf Pyrrolidon und Caprolactam basierende Materialien in der Welt haben und welche potenziellen Möglichkeiten für die Zukunft bestehen.* In Band 1 wird die Chemie der kleinen Lactam-basierten Moleküle mit ihren einzigarten Eigenschaften dargestellt.* In Band 2 werden polymere Materialien wie Polyvinylpyrrolidon und Polyvinylcaprolactam besprochen, zudem gibt der Autor einen Überblick über Homopolymerisation, Copolymerisation, die kontrollierte radikalische Polymerisation und die Polymerisation von Pyrrolidon auf Acrylatbasis.* In Band 3 werden die physikalische Chemie und die molekularen Wechselwirkungen von auf Pyrrolidon und Caprolactam basierenden Materialien untersucht.* In Band 4 wird das bereits in Band 3 angesprochene Thema der Charakterisierung erweitert, u. a. mit einer ausführlichen Darstellung der Magnetresonanztomographie (MRT) und der Fourier-Transform-Infrarot-Spektroskopie (FT-IR), der thermischen und mechanischen Eigenschaften sowie der bildgebenden Verfahren.* In Band 5 befasst sich der Autor mit pharmazeutischen Anwendungen bei Inhaltsstoffen und Materialien sowie mit den antimikrobiellen Eigenschaften und Anwendungen von auf Pyrrolidon und Caprolactam basierenden Materialien und deren Toxikologie.* In Band 6 werden die Bereiche Körperpflege- und Reinigungsprodukte, Hautpflege, transdermale Anwendungen und Wundpflege, Mundhygiene, Klebeanwendungen sowie digitale Anwendungen, darunter die Inkjet-Technologie, behandelt.Das Handbook of Pyrrolidone and Caprolactam Based Materials richtet sich an Forscher und Ingenieure in der Industrie, die sich mit der Entwicklung und Herstellung von Polymeren beschäftigen. Es ist auch für Forscher in der Wissenschaft von Interesse, die in den Bereichen Chemie, Materialwissenschaften sowie Chemieingenieurwesen und Verfahrenstechnik tätig sind.

Improve your personal and professional life with compelling strategies and practical adviceDon't Push Too Many Trolleys: And Other Tips from Navigating Life and Business teaches readers ten crucial principles required to succeed in life and business. Written by Ying Tan, Founder and CEO of a multimillion pound financial services company, Don't Push Too Many Trolleys imparts sage advice suitable for anyone, at any stage of their life.The author describes the attitudes, lessons, and traits that allowed him to become one of the youngest Vice Presidents ever at Goldman Sachs. He shows readers how he built a company from the ground up to create one of the most influential and powerful financial services companies in the UK. Full of concrete strategies and practical advice, this book provides:* A deeply personal and humble perspective on success in life and business* Actionable advice that makes a real difference in the pursuit of happiness and wealth* A front-row seat to the economic meltdown of 2008 and how the author managed to survive it with his business intactWritten for entrepreneurs, business people, financial professionals, and anyone else with an interest in improving their personal and professional life by taking full responsibility for their choices and actions, Don't Push Too Many Trolleys is an indispensable addition to the libraries of people across the world.

The most comprehensive, global guide to business model design and innovation for academic and business audiences.Business Model Innovation Strategy: Transformational Concepts and Tools for Entrepreneurial Leaders is centered on a timely, mission-critical strategic issue that both founders of new firms and senior managers of incumbent firms globally need to address as they reimagine their firms in the post COVID-19 world. The book, which draws on over 20 years of the authors collaborative theoretical and rigorous empirical research, has a pragmatic orientation and is filled with examples and illustrations from around the world.This action-oriented book provides leaders with a rigorous and detailed guide to the design and implementation of innovative, and scalable business models for their companies. Faculty and students can use Business Model Innovation Strategy as a textbook in undergraduate, MBA, and EMBA degree courses as well as in executive courses of various designs and lengths. The content of the book has been tested in both degree and non-degree courses at some of the world's leading business schools and has helped students and firm leaders to develop ground-breaking business model innovations.This book will help you:* Learn the basics of business model innovation?including the latest developments in the field* Learn how business model innovation presents new and profitable business opportunities in industries that were considered all but immune to attacks from newcomers* Learn how to determine the viability of your current business model* Explore new possibilities for value creation by redesigning your firm's business model* Receive practical, step-by-step guidance on how to introduce business model innovation in your own company* Become well-versed in an important area of business strategy and entrepreneurshipAuthors Amit and Zott anchored the book on their pioneering research and extensive scholarly and practitioner-oriented publications on the design, implementation, and performance implications of innovative business models. They are the most widely cited researchers in the field of business model innovation, and they teach at the top-ranked Wharton School of the University of Pennsylvania and the prestigious global business school IESE with campuses in Barcelona, Madrid, Munich, New York, and São Paulo.

Save on expensive professionals with this trusted bestseller!Running your own business is pretty cool, but when it comes to the financial side--accounts and payroll, for instance--it's not so cool! That's why millions of small business owners around the world count on QuickBooks to quickly and easily manage accounting and financial tasks and save big time on hiring expensive professionals.In a friendly, easy-to-follow style, small business guru and bestselling author Stephen L. Nelson checks off all your financial line-item asks, including how to track your profits, plan a perfect budget, simplify tax returns, manage inventory, create invoices, track costs, generate reports, and pretty much any other accounts and financial-planning task that turns up on your desk!* Keep up with the latest QuickBooks changes* Use QuickBooks to track profits and finances* Balance your budget* Back up your data safelyThe fully updated new edition of QuickBooks For Dummies takes the sweat (and the expense) out of cooking the books--and gives you more time to savor the results of your labors!

Use your interpersonal and communication skills as a financial professional to work successfully with clientsEmbark on a journey to further develop your career when you read People-Centric Skills: Interpersonal and Communication Skills for Financial Professionals, 2nd Edition. Business leaders consider employee communication skills and critical thinking abilities as essential elements for success. In their work, all professionals must communicate clearly and rely on their interpersonal skills to be successful.This second edition of People-Centric Skills shares the fictional story of Dalton Zimmer, executive coach and public speaker. Dalton, all the while juggling his business, kids and social life, provides coaching and communication strategies for handling challenging situations faced by his clients.This insightful narrative will help you expand communication and soft skills as a CPA, auditor, financial planner or other financial professional.As Generation Z is entering the work force, the communication gap between Z and Boomers or Generation X is widening significantly. New to the second edition, you'll find a discussion of communication between generations and how to bridge them as a financial professional.You can be a more people-centric leader as you engage with a wide range of clients and associates. This book can be a first step to improving interpersonal and communication skills as you continue to develop in your career.

Integrate Agile methodology into your business with this stunning guide to the latest management techniquesCorporate Agility is the must-have guide on adopting Agile methodology for businesses of all shapes and sizes. This visually stunning book delivers six key lessons that you must learn in order to effectively join the Agile world. You'll learn the ins and outs of the traditional approach, helping you answer the questions "Why Agile?" and "Why now?" You'll also discover new, more efficient Agile strategies that will help you lead your enterprise to increased collaboration, more flexibility, and better business results.Based on the latest practice and research, and drawing on years of experience at the author's own leading consultancy, Corporate Agility features a beautiful 4-color design that helps you visualize powerful strategic ideas, so you can understand and implement them right away. Unlike other books on the market, this title helps you reinterpret key Agile management concepts in a way that will work for your specific needs.* Gain a clear understanding of traditional Agile methodology, the history of Agile, and the benefits to organizations of all shapes and sizes* Discover cutting-edge Agile strategies that push Agile thinking forward and increase performance efficiency* Learn the 6 "Agilessons" that underpin all successful Agile transformations* Follow real-world case studies from leading businesses that have successfully made the leap into Agile operationsOrganizational leaders will love this digestible, forward-thinking guide written by one of America's fastest rising strategic execution gurus.

Establishing an effective partnership and achieving improved outcomes for investors and management teams during the hold cyclePrivate equity represents a productive and fast-growing asset class--building businesses, creating jobs, and providing unlimited opportunity for investors and management teams alike, particularly if they know how to work together in candid and effective partnerships. Restructuring the Hold demonstrates how investors and managers can best work together to optimize company performance and the associated rewards and opportunities for everyone, not just the investors.Through brief references to the parable of the Gramm Company, a middle market portfolio company, readers will follow the disappointments and triumphs of a management team experiencing their first hold period under private equity ownership, from the day they get purchased through the day they get sold. Restructuring the Hold provides the reader both general knowledge and more detailed better practices and frameworks relating to specific time periods during the hold. Within this book readers will find:* An examination of a typical middle-market private equity hold period* Guidance for newly acquired management teams on what to expect during the hold period* Descriptions of better practice operating cadence between investors and management teams* Examples of effective partnerships between investors and management teams* Discussions of topics relevant to typical hold periods, including organizational structures, operations improvement, selling pipelines and acquisition integrationsWith guidance from Restructuring the Hold, private equity principals and portfolio company executives can take steps toward greater collaboration and better outcomes. Through updated practices and strong relationships, they can partner effectively to improve portfolio company performance, which will lead to better outcomes for both investors and management teams.

Starting from the practical viewpoint of, "I would rather be approximately right than perfectly wrong" this book provides a commonsense comprehensive framework for small business valuation that offers solutions to common problems faced by valuators and consultants both in performing valuations and providing ancillary advisory services to business owners, sellers, and buyers. If you conduct small business valuations, you may be seeking guidance on topics and problems specific to your work. Focus on What Matters: A Different Way of Valuing a Small Business fills a previous void in valuation resources. It provides a practical and comprehensive framework for small and very small business valuation (Companies under $10 million of revenues and often under $5 million of revenues), with a specialized focus on the topics and problems that confront valuators of these businesses.Larger businesses typically have at least Reviewed Accrual Accounting statements as a valuation starting point. However, smaller businesses rarely have properly reviewed and updated financials. Focus on What Matters looks at the issue of less reliable data, which affects every part of the business valuation. You'll find valuation solutions for facing this challenge.As a small business valuator, you can get direction on working with financial statements of lower quality. You can also consider answers to key questions as you explore how to value each small business.* Is this a small business or a job?* How much research and documentation do you need to comply with standards?* How can you use cash basis statements when businesses have large receivables and poor cutoffs?* Should you use the market method or income method of valuation?* Techniques that improve reliability of the market method multiplier* How might you tax affect using the income method with the advent of the Estate of Jones and Section 199A?* Do you have to provide an opinion of value or will a calculation work?* How do you calculate personal goodwill?* As a valuation professional how can you bring value to owners and buyers preparing to enter into a business sale transaction?* How does the SBA loan process work and why is it essential to current small business values?* What is the business brokerage or sale process and how does it work?* How do owners increase business value prior to a business sale?This book examines these and other questions you may encounter in your valuation process. You'll also find helpful solutions to common issues that arise when a small business is valued.

Animal Models for the Development of Cancer ImmunotherapyProvides readers with a clear understanding of the value and challenges of using common and emerging preclinical models in cancer immunotherapy research and development.Animal models are essential tools for studying a range of issues in preclinical and clinical research on therapies targeting cancerous tumors. As clinical trials of advances in cancer immunotherapy are predicted to outpace preclinical research in the near future, there remains an urgent need to develop better animal models for preclinical evaluation of novel modulators. Animal Models for the Development of Cancer Immunotherapy provides a detailed overview of different preclinical model systems for development of novel cancer immunotherapies while highlighting how key aspects of individual models translate into clinical findings.Covering the introduction, development, and therapeutic applications of animal models for cancer immunotherapy, this comprehensive volume helps pharmacologists identify suitable animal models, design pharmacological or translational studies, and advance their mechanistic understanding of therapeutic agents, and increase the possibility of success for novel immunotherapies in clinical settings. Chapters written by prominent leaders in the field address specific models that evaluate immuno-oncology drugs are supported by in-depth case studies and extensive references throughout.* Emphasizes the importance of modeling tumor metastasis in preclinical models for efficient translation of findings into the clinic* Explores recently discovered mechanisms of resistance and their preclinical modeling* Highlights the unique characteristics and features of autologous and allogeneic approaches for humanization of mouse models* Reviews development of bone marrow-liver-thymus (BLT) immune humanized mice and emerging alternative models such as genetically engineered mouse models (GEMM)* Discusses alternative animal models for cancer research such as severe combined immunodeficiency (SCID) pigsAnimal Models for the Development of Cancer Immunotherapy is an essential resource for scientists and researchers in the pharmaceutical and biotechnology industries, medicinal chemists and biochemists, cell and molecular biologists, pharmacologists, immunologists, and clinicians.

Explores the complex physico-chemical processes involved in active volcanism and dynamic magmatismUnderstanding the magmatic processes responsible for the chemical and textural signatures of volcanic products and igneous rocks is crucial for monitoring, forecasting, and mitigating the impacts of volcanic activity.Dynamic Magma Evolution is a compilation of recent geochemical, petrological, physical, and thermodynamic studies. It combines field research, experimental results, theoretical approaches, unconventional and novel techniques, and computational modeling to present the latest developments in the field.Volume highlights include:* Crystallization and degassing processes in magmatic environments* Bubble and mineral nucleation and growth induced by cooling and decompression* Kinetic processes during magma ascent to the surface* Magma mixing, mingling, and recharge dynamics* Geo-speedometer measurement of volcanic events* Changes in magma rheology induced by mineral and volatile contentThe American Geophysical Union promotes discovery in Earth and space science for the benefit of humanity. Its publications disseminate scientific knowledge and provide resources for researchers, students, and professionals.

FOUNDATIONS OF CHEMISTRYA foundation-level guide to chemistry for physical, life sciences and engineering studentsFoundations of Chemistry: An Introductory Course for Science Students fills a gap in the literature to provide a basic chemistry text aimed at physical sciences, life sciences and engineering students. The authors, noted experts on the topic, offer concise explanations of chemistry theory and the principles that are typically reviewed in most one year foundation chemistry courses and first year degree-level chemistry courses for non-chemists.The authors also include illustrative examples and information on the most recent applications in the field. Foundations of Chemistry is an important text that outlines the basic principles in each area of chemistry - physical, inorganic and organic - building on prior knowledge to quickly expand and develop a student's knowledge and understanding.Key features include:* Worked examples showcase core concepts and practice questions.* Margin comments signpost students to knowledge covered elsewhere and are used to highlight key learning objectives.* Chapter summaries list the main concepts and learning points.

The first book to comprehensively address the theory, kinematic modelling, numerical simulation and applications of vibration assisted machiningVibration Assisted Machining: Theory, Modelling and Applications covers all key aspects of vibration assisted machining, including cutting kinematics and dynamics, the effect of workpiece materials and wear of cutting tools. It also addresses practical applications for these techniques. Case studies provide detailed guidance on the design, modeling and testing of VAM systems. Experimental machining methods are also included, alongside considerations of state-of-the-art research developments on cutting force modeling and surface texture generation.Advances in computational modelling, surface metrology and manufacturing science over the past few decades have led to tremendous benefits for industry. This is the first comprehensive book dedicated to design, modelling, simulation and integration of vibration assisted machining system and processes, enabling wider industrial application of the technology. This book enables engineering students and professionals in manufacturing to understand and implement the latest vibration assisted machining techniques. Highlights include:* Comprehensive coverage of the theory, kinematics modelling, numerical simulation and applications of vibration assisted machining (VAM)* Case studies with detailed guidance on design, modelling and testing of VAM systems, as well as experimental machining methods* Discussion of state-of-the-art research developments on cutting force modelling and surface texture generation* Coverage of the history of VAM, its current applications and future directions for the technologyVibration Assisted Machining: Theory, Modelling and Applications provides engineering students, researchers, manufacturing engineers, production supervisors, tooling engineers, planning and application engineers and machine tool designers with the fundamentals of vibration assisted machining, along with methodologies for developing and implementing the technology to solve practical industry problems.