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This volume thoroughly covers the major molecular and immunological techniques utilized for pathogenesis research of Hemophilus influenza, which is the second leading bacterial cause of pneumonia. Techniques are also provided for plasmid analysis, proteomics, genomics, DNA arrays and mutagenesis.

Since the first recognition of outbreaks of cerebrospinal or spotted fever at the end of the nineteenth and the beginning of the twentieth centuries, the menace of the meningococcus has been high on the list of public health prio- ties.

Leading bioethicists and philosophers examine and debate the question of how the health care system should deal with using complimentary and alternative medicines.

This collection of basic and advanced protocols permits biotechnologists to use plants rather than single cell fermentation systems for expressing recombinant proteins.

Leading experts in the use of MRI explain its basic principles and demonstrate its power to understand biological processes with numerous cutting-edge applications.

Probiotics in Pediatric Medicine provides clinicians a tool to understand the current evidence for the role of probiotics in various pediatric disorders related to the gastrointestinal as well as the extra-intestinal tract.

One comment often repeated to me by coworkers in the biotechnology industry deals with their frustration at not understanding how their particular roles fit into their company's overall scheme for developing, manufacturing, and marketing biomedical products.

The chapters discuss the use and interpretation of video-aided quantification of zebrafish behaviors, describe novel assays commonly used to quantify emotionality, learning, memory, and social behaviors in zebrafish, and instruct how to quantify endocrine responses and correlate them with behavior.

The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful.

In this updated third edition, expert physicians assemble user-friendly, clinically-oriented guides to aid in the day-to-day management of the allergic patient. This book is intended for the front-line physician who cares for allergic patients.

This authoritative book investigates a wide range of pain mechanisms. It seeks to lead scientists closer to the ultimate goal of improving the quality of life and relieving the unbearable burden of chronic pain for millions of people throughout the world.

This Methods in Molecular Biology(TM) book covers knowledge dissemination and theoretical assessment of OR structure and function, plus development and use of expression systems and experimental functional analysis. Offers reproducible protocols, tips and more.

A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use.

Patients with chronic pain present a unique set of challenges to the primary care clinician. In this updated book, leading pain specialist Dawn A. Marcus, MD, offers practical and succinct evidence-based approaches to the diagnosis and treatment of pain.

Part of Springer's "The Receptors," series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a key role in the regulation of numerous behaviors.

As part of the Current Clinical Oncology series, Lymphoma: Diagnosis and Treatment will be of value to medical oncologists, hematologists, radiation oncologists, and all physicians involved in the care of patients with lymphoid malignancies.

This comprehensive book, intended for those providing medical care to children, provides an overview of pediatric pain. Each chapter provides an overview of the problem, followed by a "hands on" description of relevant assessment and intervention strategies.

In this book, experts provide a comprehensive review of current knowledge regarding nutrition and dietary management for the complex set of rheumatic conditions.

With all of the misinformation regarding the effects of creatine supplementation on health and sports performance, this book brings together the information on how creatine affects body composition, exercise performance, and health.

In view of the numerous failures of clinical trials aimed at improving stroke therapy, the role and potential benefit of experimentally modeling focal cerebral ischemia in rodents has been debated.

A comprehensive treasury of the key molecular biology methods - ranging from DNA extraction to gene localization in situ - needed to function effectively in the modern laboratory. Each of the 120 highly successful techniques follows the format of the much acclaimed "Methods in Molecular Biology" series.

Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse.

Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a "development cell." That new integrated approach is known as stem-cell biology;

Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a unique, practical resource for health care providers dealing with hyperglycemia in the inpatient setting.

In this essential new volume, Volume 13: Membrane and Desalination Technologies, a panel of expert researchers provide a wealth of information on membrane and desalination technologies.

Lung Pathology: A Consultative Atlas and its companion CD complement each other as a novel and substantive approach to teaching the complex elements of pulmonary pathology.

Applications of Biotechnology in Cardiovascular Therapeutics collects writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease. Selected references are included in each chapter, and the text is supplemented by a variety of useful tables and figures.

Presenting individual research contributions from scientists in the NIAID, this volume provides new research findings in immunology, infectious diseases, and vaccine research. Readers will find the current work in the Division of Intramural Research (DIR) and the Vaccine Research Center (VRC).