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Health Effects of the Fukushima Nuclear Disaster provides a multidisciplinary retrospective on the health consequences on the population the first decade after the Fukushima nuclear disaster. Sections 1 and 2 of the book begins with an introduction and an overview of the developments surrounding the Fukushima accident. Section 3 discusses topics such as the physical health impact of radiation exposure as well as diseases that resulted from long-term evacuation. Section 4 examines the psychological factors and the social impact of the disaster and how their combined influence affected the physical and mental wellness of the population. The book concludes with Section 5 which covers the mitigation strategy for treatment and care of psychological health issues resulting from the disaster. The book contains expert contributions from those who have first-hand experience in the recovery efforts and are still actively researching the impact of the disaster. Health Effects of the Fukushima Nuclear Disaster provides readers with a coherent, multi-dimensional narrative about the physical, psychosocial, and psychological aspects of the decade-long aftermath of the Fukushima nuclear disaster.

Electrospun and Nanofibrous Membranes: Principles and Applications covers the fundamental basic science and many engineering aspects of electrospun membrane technology and nanofibers, membrane design and membrane processes. The book comprehensively reviews a wide range of applications including pressure-driven processes, MD process, batteries, oil-water separation, air filtration, drug delivery, fuel-cells, and ion-exchange membranes, as well as antimicrobial membranes. Electrospun and Nanofibrous Membranes will be useful for a range of audiences: chemical, polymer, and materials engineers; professors and graduate students working on membrane-based separation technology and electrospun nanofibers; as well as R&D engineers in industry working with applications including water and wastewater treatment, desalination, drug delivery and tissue engineering, new generation of batteries, fuel cells, and air filtration.

Training in clinical chemistry is acquired via different avenues that include didactic lectures on pathophysiology of disease, methodologies and practical aspects of testing, and through attendance of operations meetings, sign-out sessions, seminars and tutorials. There is little instruction on how to apply the vast amount of knowledge gained in the process to practice. In other branches of medicine, cases are regularly presented with clinical information and therapeutic interventions which form the basis of training. Diagnostic Reasoning: Laboratory-Based Case Studies in Clinical Chemistry fills this gap for clinical chemistry. The concise and practical approach of the book, including real-life scenarios, is an excellent resource for pathology trainees, clinical laboratory science students, clinical chemistry fellows, clinical laboratory professionals, and clinicians. These cases help professionals remain competent in the field and be successful in their board exams. The cases are stated as they present, often with no or few clinical details accompanying the sample request with only barcoded samples arriving into the laboratory. In a busy laboratory, thousands of these cases are received daily and it is impossible to review the clinical information associated with the specimens.

Water-Formed Deposits: Fundamentals and Mitigation Strategies wholly presents the important issue of deposits in aqueous systems, both industrial and biological. By analyzing causes, mechanisms and mitigation strategies, the book helps researchers/engineers/end-users gain a fundamental understanding of the issues underlying deposit formation and mitigation. It covers numerous, fundamental aspects of water-formed deposits, while also giving an applications¿ perspective. The book's goal is to assist the reader in his/her understanding of the important issues of scale formation, while also helping with potential solutions.

Sensory Analysis for the Development of Meat Products: Methodological Aspects and Practical Applications highlights the application of sensory analysis in the development of meat products. It presents the background and historical aspects of sensory evaluation on the characterization and development of meat products. Divided into two sections, the book discusses fundamental concepts, methodological approaches, statistical analysis, innovative methods, and presents case studies using these approaches. Chapter include definitions, applications, literature reviews, recent developments, methods and end of chapter glossaries. Researchers in sensory analysis and meat processing, as well as new product developers, will benefit from this comprehensive resource on the topics discussed.

Climate Smart Small-Scale Hydro Power Plants provides empirical guidance to practitioners seeking to optimize design and adapt the operation of small hydro power plants (SHPPs) to mitigate climate change. The work covers current positions, practices and impacts of SHPP as part of a diversifying sustainable energy mix threatened by the uncertain vagaries of climate change - including violent flooding, inconsistent rain fall, poor catchment management, and water flow rises. In addition, it presents an argument for 'climate smart' SHPP planning and design which integrates qualitative and quantitative climate-change context-sensitive aspects into the design of SHPP systems.Chapters review practical examples of hydro-ecological regimes where small hydro power plants play a vital component in the overall energy mix, focusing on social, ecological and economic dimensions of safeguarding, key policies and operational practices. Case studies are used to assess progress and future steps in achieving SHPP climate smart systems, blending comparative review, integration and analysis.

As opposed to conventional electrochemical sensors, nanomaterials-based sensors are active and effective in their action with even a minute concentration of analyte. A number of research studies are bringing about an evolution in their development and advancement because of their unique and effective properties. Nanoscale electrochemical sensors have applications in almost every field of life including the detection of neurochemicals, heavy metals, energy components, body fluids, biological matrices, cancer relevant biomolecules, aromatic hydrocarbons, also in playing their role in food science because of their capability in providing quality control and safety. There is a need to develop these nanomaterials-based electrochemical sensors to be more widely available for accurate sensing of minute concentrations especially in the case of heavy metal detection, biofluids, and other biomaterials. This book outlines the major preparation, fabrication and manufacture of nanomaterials-based electrochemical sensors, as well as detailing their principle medical, environmental and industrial applications in an effort to meet this need.This book is a valuable reference source for materials scientists, engineers, electrochemists, environmental engineers and biomedical engineers who want to understand how nanomaterials-based electrochemical sensors are made, and how they are used.

Approx.620 pages

Early Detection of Alzheimer¿s Disease: Biological and Technological Advances aims to introduce to a wide audience the high global priority problem of detecting AD prior to dementia onset. According to the Alzheimer¿s Association, 5.8 million Americans are living with Alzheimer¿s and care costs will cost the nation approximately $290 billion (2019 Alzheimer¿s Disease Facts and Figures). With the failure of recent AD drug trials, many hypothesize that by the time symptoms appear, it is too late to be treated. Early detection can offer benefits such as more choice of medications, ability to participate in clinical trials, more time for family and for care planning. This book outlines potential solutions to the above problem using opportunities arising from the technology revolution, advances in neuroscience, and molecular biology. Most importantly, it discusses a paradigm shift from a reactive to a proactive diagnostic approach, aiming to detect disease before occurrence of symptoms. Topics covered include the use of sensing technologies (e.g. smartphones, smartwatches, Internet of Things) to detect early disease-related changes, the application of data science (machine learning/AI) to extract otherwise invisible disease features from these datasets and the potential to personalize diagnosis based on tracking changes in individual behaviours. Advances in blood-based biomarkers, brain imaging, and the potential for early diagnosis to aid interventions (lifestyle, dietary, pharmacological) to delay future development of dementia are also discussed.

Building automation systems and digital technologies are highly relevant for the environmental and energy performance of buildings. However, a clear gap remains between architectural engineering and the use of such technologies. Building Automation and Digital Technologies shows how to assimilate automation and digital technologies into making buildings smarter and more environmentally sustainable. This book shows why architects need smart and digital systems in building design and construction and promotes innovative technological tools for improving sustainability. It focuses on the development of automated environmental conditions and how new technology informs architectural engineering. The book also provides new evidence on the impact of building automation systems and digital technologies, such as the Internet of Things, artificial intelligence, and information and communication technology for developing a performance-based approach to the environmental sustainability of buildings, and provides a key reference for architects on how digital technology can inform their practice. Its four chapters cover: developing strategies for improving sustainable and smart buildings; architectural practice and construction technology; creativity and innovation in building automation systems; and the use phase of buildings. Building Automation and Digital Technologies meets a critical need for a sustainable and smart built environment from an architectural perspective, providing an important reference to architects and professionals in related fields by demonstrating the assimilation of the latest information and automation technologies.

Mass Production of Beneficial Organisms: Invertebrates and Entomopathogens, Second Edition explores the latest advancements and technologies for large-scale rearing and manipulation of natural enemies while presenting ways of improving success rate, predictability of biological control procedures, and demonstrating their safe and effective use. Organized into three sections, Parasitoids and Predators, Pathogens, and Invertebrates for Other Applications, this second edition contains important new information on production technology of predatory mites and hymenopteran parasitoids for biological control, application of insects in the food industry and production methods of insects for feed and food, and production of bumble bees for pollination.Beneficial organisms include not only insect predators and parasitoids, but also mite predators, nematodes, fungi, bacteria and viruses. In the past two decades, tremendous advances have been achieved in developing technology for producing these organisms. Despite that and the globally growing research and interest in biological control and biotechnology applications, commercialization of these technologies is still in progress. This is an essential reference and teaching tool for researchers in developed and developing countries working to produce "natural enemies¿ in biological control and integrated pest management programs.

New Strategies Targeting Cancer Metabolism: Anticancer Drugs, Synthetic Analogues and Antitumor Agents presents up-to-date synthetic strategies for three categories of antimetabolites: antifolates, purines and pyrimidines, the main classes of antimetabolites which are integrated into various pharmaceutical agents. Many of these antimetabolites are considered potent chemotherapeutic agents which have great potential impact on medical research. These main classes of antimetabolites are used in the treatment of critical diseases including cancer, malignancies, autoimmune diseases, and many other non-malignant diseases. Antineoplastic drugs such as alkylating agents which have significant effects are described. Novel synthetic strategies for many anticancer alkylating agents including nitrogen mustards, chlorambucil, melphalan, ifosamide, oxaliplatin and temozolomide are explored. Natural products have offered some of the most significant drugs for treating cancer, as many drugs currently in clinical use are derived from natural products as camptothecins, vinca alkaloids, and derivatives of podophyllotoxin. They provide a contribution that is essential for modern drug discovery and development. In this book, insights into a broad array of novel compounds are reviewed, well-recognized synthetic approaches are emphasized for further anticancer drug development and discovery, and the biological evaluation of novel synthesized compounds are included. This comprehensive reference is a valuable resource for medical chemists working in drug discovery and development, as well as pharmacologists and biochemists working in related fields.

RNA Therapeutics: The Evolving Landscape of RNA Therapeutics provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery. International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation and protein function. Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation, the therapy development process from the lab to the clinic, and novel RNA-based therapies currently in development.

Intensification of Sorption Processes: Active and Passive Mechanisms introduces a number of selected, advanced topics in sorption processes/process intensification, covering both theoretical and applicable aspects. The first part of the book is devoted to the study of sorption processes based on active mechanisms, including ultrasonic, microwave, high-gravity, electrical and magnetic fields, while the second part covers passive mechanisms like nanostructures and nanofluids, membrane, supercritical fluids and sorption processes based on geometry design and equipment structure. The focus of the book is on key aspects of novel process intensification technologies (processes and equipment), i.e., absorption and adsorption, working principles, and design and applications.

Smart Urban Mobility: Transport Planning in the Age of Big Data and Digital Twins explores the data-driven paradigm shift in urban mobility planning and examines how well-established practices and strong data analytics efforts can be better aligned to fit transport planning practices and "smart" mobility management needs. The book provides a comprehensive survey of the major big data and technology resources derived from smart cities research which are collectively poised to transform urban mobility. Chapters highlight the important aspects of each data source affecting applicability, along with the outcomes of smart mobility measures and campaigns.Transport planners, urban policymakers, public administrators, city managers, data scientists, and consulting companies managing smart city interventions and data-driven urban transformation projects will gain a better understanding of this up-and-coming research from this book's detailed overview and numerous practical examples and best practices for operational deployment.

Solar Activity, Events, and Galactic Cosmic Radiation: Effects on the Earth's Atmosphere: An Introduction give students and researchers in Atmospheric Science, Solar Physics and Climatology a more concise perspective on the Earth's atmospheres and how they are affected by solar emissions. It reviews a wide range of topics relating to the effects from solar activity on the Earth's climate, including impacts on the energy budget, the effect of emissions on tides and dynamics, how solar emissions change on different time scales, and the ramifications of modeling paleoclimates. By providing greater insight on how solar emissions change as they travel through the atmosphere, this book guides the reader on how to present these emissions, along with observations and indices.

Antioxidants Effects in Health: The Bright and the Dark Side examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants¿ historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.

Approx.340 pages

Approx.164 pages

Handbook of Economic Stagnation takes a broad view, including contributions from orthodox and heterodox economists who examine situations in countries and worldwide regions, including Japan and the Euro area. To be sure, stagnation is periodically relieved by short economic bursts usually brought on by unsustainable asset price bubbles. Once the bubbles burst, stagnation returns. This book's fresh, comprehensive approach to the topic makes it the premier source for anyone affected by these cycles.

Statistical Modeling using Local Gaussian Approximation extends powerful characteristics of the Gaussian distribution, perhaps, the most well-known and most used distribution in statistics, to a large class of non-Gaussian and nonlinear situations through local approximation. This extension enables the reader to follow new methods in assessing dependence and conditional dependence, in estimating probability and spectral density functions, and in discrimination. Chapters in this release cover Parametric, nonparametric, locally parametric, Dependence, Local Gaussian correlation and dependence, Local Gaussian correlation and the copula, Applications in finance, and more. Additional chapters explores Measuring dependence and testing for independence, Time series dependence and spectral analysis, Multivariate density estimation, Conditional density estimation, The local Gaussian partial correlation, Regression and conditional regression quantiles, and a A local Gaussian Fisher discriminant.