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Covers groundwater's role in the hydrologic cycle and in water supply, contamination, and construction issues. This book is suitable for students and instructors in the geosciences (with focuses in hydrology, hydrogeology, and environmental science), and as a reference work for professional researchers.

Deep Learning in Personalized Healthcare and Decision Support discusses the potential of deep learning technologies in the healthcare sector. The book covers the application of deep learning tools and techniques in diverse areas of healthcare, such as medical image classification, telemedicine, clinical decision support system, clinical trials, electronic health records, precision medication, Parkinson disease detection, genomics, and drug discovery. In addition, it discusses the use of DL for fraud detection and internet of things. This is a valuable resource for researchers, graduate students and healthcare professionals who are interested in learning more about deep learning applied to the healthcare sector. Although there is an increasing interest by clinicians and healthcare workers, they still lack enough knowledge to efficiently choose and make use of technologies currently available. This book fills that knowledge gap by bringing together experts from technology and clinical fields to cover the topics in depth.

Starch in Food: Structure, Function and Applications, Third Edition is now fully updated with eleven new chapters covering "hot" areas for starch applications, such as starch-based pickering emulsifiers, starch for structuring gluten-free bread products, and starch microspheres for encapsulation of probiotic bacteria. Sections illustrate how plant starch can be analyzed and modified, including chapters on analysis of starch molecular structure, molar mass and size, the relationship between structure and digestion of starch, sources of starch, including new chapters on cereal, root and tuber and pulse starches, and starch applications, with a new chapter on utilizing starches in product development, in baked products and in gluten-free bread. Starch selection is one of the most complex areas for a product developer, yet starch is key to solving formulation challenges when developing products to meet many of the emerging consumer trends. This book aids the end user on acquiring knowledge on fundamental starch aspects, such as granular and molecular structure and properties, analysis, biosynthesis and general functionality of starch in foods.

Bioengineered Nanomaterials for Wound Healing and Infection Control is a key reference for those working in the fields of materials science, pharmacy, nanotechnology, biomedical engineering and microbiology. Bioengineered nanomaterials have unique physicochemical properties which promote accelerated wound healing and treatment of infections. The biosynthesis of these nanomaterials also offers a clean, safe and renewable alternative to traditional nanomaterials, helping reduce environmental impact alongside antibacterial resistance.

Haemodynamics and Immune Defence: Discoveries in Pharmacology, Second Edition, Volume Three presents selected articles from the historic Discoveries in Pharmacology series that are enhanced with commentary from contemporary scholars who discuss the reception and importance of each chapter along with an updated bibliography on the subject and contributions from those involved in Nobel Prize winning discoveries and pioneering advancements in Pharmacology. This volume brings forth discussions on key discoveries in hemodynamics and immune defense, including chapters on penicillin by Dr. Selwyn and asthma by Dr. Brocklehurst. Academic and industry researchers in pharmacology and medicine, as well as advanced students in the area, will find this useful teaching tool and launch to new discoveries. Chapters can also be used to supplement course material in pharmacology and medical courses. It will also be of interest to those who are interested in the history of medicine.

Global Perspectives of the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans: Zoonotic, Epizootic, and Anthropogenic Transmission Viral Pathogens elaborates on the current knowledge surrounding the transmission of zoonotic RNA viruses from different wild animal species to humans, including updates on the reverse transmission of pathogens to humans across the globe, with coverage of rodents, pigs, birds and primates. This reference goes beyond the phenomena occurring in African and American regions to provide further study of zoonotic pathogens from the entire world, including various parts of Asia such as India. The book comprehensively covers new knowledge on many diverse wild primate species for a global perspective on the phenomena of cross-species transmissions of pathogenic RNA viruses. Against the backdrop of the current global Covid-19 pandemic, this reference helps solve the problem of incomplete knowledge on global epidemiology of zoonotic RNA viruses. RNA viruses have pandemic, epidemic and epizootic potentials caused by Influenza viruses, Avian Influenza viruses, and other infectious viruses.

The coronavirus pandemic that began in 2019 brought to the fore the presence of a significant minority of individuals who strongly oppose vaccination. This opposition is by no means recent. Ever since the very first attempts to immunize individuals, opposition has been intense in some societies. The reasons for this opposition range from religious to political to medical. Although vaccines have eliminated smallpox and largely eliminated polio and measles, opposition to vaccination persists and,  in some countries, has grown stronger. A History of Vaccines and Their Opponents seeks to describe the history of this opposition as well as its changing rationale over the years and in different societies. The discussion may ultimately provide some suggestions for reducing hesitancy in the future.

Recent Advances in Nanocarriers for Pancreatic Cancer Therapy reviews thriving strategies concerning pancreatic cancer therapy, thoroughly describing the most recent developments in emerging modern drug delivery systems focused on, and derived from, nanotechnology. By providing a holistic understanding of the molecular pathways, conventional therapy and novel nanocarriers mediated drug delivery against pancreatic cancer, this work can be considered a complete package. The book offers a solution to the dissemination of data from a broad range of resources by providing an overview of the molecular pathways and conventional therapy of pancreatic cancer, the application of various nanocarriers, and more. This book equips scientists, clinicians and students to make rational treatment approaches based on nanomedicine for improving and extending the human life against pancreatic cancer.

Pharmaceutical Biotechnology in Drug Development summarizes key concepts and the latest developments of biotechnology applied to the development of biopharmaceuticals. Chapters present a comprehensive collection of introductory biotechnology technologies and their modern concepts and cover pharmacokinetic and pharmacodynamic behavior of biopharmaceuticals and modification techniques of amino acids and nucleic acid. Other sections focus on topics such as gene therapy, immunological preparations and nanoparticles which are the major contributions of pharmaceutical biotechnology. Final chapters discuss emerging techniques in the field of pharmaceutical biotechnology to meet current patient and health care demand. This book is an essential reference useful for pharmaceutical scientists, clinicians and academic researchers who want easy access to up-to-date practices of pharmaceutical biotechnology. Corporate researchers will also benefit from this book's succinct and objective content structure.

Precision Agriculture: Evolution, Insights and Emerging Trends presents a complete guide from foundational concepts to the economic, commercial and environmental implications of the approach. Showcasing recent research improvements, future trends, and highlighting innovative use of machine vision, artificial intelligence, UAVs, drones, IoT and data analytics to promote sustainable agriculture, the book brings the reader up-to-date with understanding and implementing this targeted practice. From the basic elements of agronomy to insights on reflectance and remote sensing indices, chapters use summary abstracts, case studies and real-world examples of implementing the tools of precision agriculture (PA) to demonstrate the latest advances. It includes explanations on the origin of the intra-plot variability of a culture (spatial and temporal), different types of existing sensors, controllers and site-specific management. The book further explores yield monitoring, weed, disease and pest control, automated irrigation systems, PA tools for variable rate application of inputs within the field, and data processing methods. By also exploring the economic profitability of precision farming approaches, and its utility for sustainable agriculture, Precision Agriculture: Evolution, Insights and Emerging Trends is a truly comprehensive view of this important approach to improving global agriculture production. Scientists, researchers, policymakers, graduate and postgraduate students, and engineers in the related fields of agriculture, computer science and engineering will benefit from this book.

Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied. Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness. Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity. A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed. Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout this book, importance is placed on inference-moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness.

Yasargil Microneurosurgery Study Guide is designed for effective learning and study of the neurosurgical principles contained in seminal microneurosurgery textbooks. From normal microsurgical anatomy to aneurysms, arteriovenous malformations, and CNS tumor microsurgery, this study guide provides a question-and-answer format to knowledge of the background, anatomy, and techniques of microneurosurgery. This work is a practical guide to the application of microneurosurgery to a variety of brain conditions, including intracranial aneurysms, extrinsic and intrinsic tumors, while providing guidance on instrumentation and equipment, neuroanesthesia, complications, and more. This practical book is ideal for neurosurgeons, neurologists, neuroanatomists, and other technical experts with a clinical interest in brain microsurgery.

Medical and Healthcare Robotics: New Paradigms and Recent Advances provides an overview and exclusive insights into current trends, the most recent innovations, and concerns in medical robotics. The book covers the major areas of medical robotics, including rehabilitation devices, artificial organs, assistive technologies, service robotics, and robotic devices for surgery, exploration, diagnosis, therapy, and training. It highlights the limitations and the importance of robotics and artificial intelligence for medical and healthcare applications. The book is a timely and comprehensive reference guide for undergraduate-level students, graduate students, and researchers in the fields of electrical engineering, mechanical engineering, mechatronics, control systems engineering, and biomedical engineering. It can be useful for master's programs, leading consultants, and industrial companies. The book can be of high interest for physicians and physiotherapists and all technical people in the medical and biomedical fields.

Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures.

Textile reinforcement forms (preforms) play an important role in determining the properties of the final composite and product. The preform formation process provides precise control of the fiber architecture and orientation using a suitable textile manufacturing technique. While the techniques employed for preparing glass and carbon preforms are well-known, there is still a gap in understanding on how to prepare natural preforms for composite reinforcements. Multiscale Textile Preforms and Structures for Natural Fiber Composites will bridge this gap by presenting unified knowledge on the relevant preform preparation techniques and resulting fiber architectures. Emphasis is on the structural parameters of each preform and their effect on the final composite properties. This book assembles information and knowledge on natural fiber reinforcement forms, including conventional forms, such as spun yarn, woven, knitted, nonwoven, braided, and comingled. These are illustrated and classified into one-, two-, and three-dimensional reinforcements. This book also includes information on nonconventional preform formation techniques such as unidirectional tapes, pre-impregnated preforms, spread tows, and tailored fiber placement.

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. This will be a complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.

Electricity Cost Modeling Calculation: Regulations, Technology, and the Role of Renewable Energy, Second Edition delivers an updated view on pricing models, regulation, technology and the role renewable energy is starting to take in electricity. Starting with fundamental concepts on market structure and the increase in international regulations, the book includes cubic cost modeling cases and updated literature reviews for deeper research. Other sections cover more advanced quantitative methods such as load forecasting, updated rate designs, and the marginal cost of electricity in the United States. Includes applications will help reduce greenhouse gas emissions, thus making the reference relevant for today''s power markets. This book gives today''s engineers a practical guide on the latest techniques in electricity pricing and applications for today''s markets. Provides readers with updated, international regulations and the role of renewable energy sources Bridges the gap between foundational concepts and advanced quantitative aspects, including updated practical case studies Helps readers understand the appropriate rate/tariff structure for efficient use of electricity and renewable options

Molecular Biology, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics, along with expanded coverage of RNAi, CRISPR, and more ensuring topical content for a new class of students. This volume effectively introduces basic concepts that are followed by more specific applications as the text evolves. Moreover, as part of the Academic Cell line of textbooks, this book contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles form the basis of case studies found in the associated online study guide that is designed to tie current topics to the scientific community. Winner of a 2020 Textbook Excellence Award (College) (Texty) from the Textbook and Academic Authors AssociationContains new chapters on non-coding RNA, genome defense, epigenetics and epigenomicsFeatures new and expanded coverage of RNAi, CRISPR, genome editing, giant viruses and proteomicsIncludes an Academic Cell Study Guide that ties all articles from the text with concurrent case studies Provides an ancillary package with flashcards, online self-quizzing, and PowerPoint slides with images