Bøker utgitt av Elsevier Science Publishing Co Inc

Genome Stability: From Virus to Human Application covers the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, with the latter including major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, as well as changes in genome stability in response to aging. Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. This book teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments. The book also covers how epigenetic factors contribute to genome stability and how species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner.Includes a collection of chapters on genome stability research from various kingdoms, including topics such as epigenetics and transgenerational effectsProvides the first comprehensive coverage of the differences in the mechanisms utilized by different organisms to maintain genomic stabilityContains applications of genome instability and its effect on human diseasesExplains how various species maintain the fine balance in genome stability and genome diversification in response to their environments

In 2016 Current Topics in Developmental Biology (CTDB) will celebrate its 50th or "golden┐ anniversary.á To commemorate the founding of CTDB by Aron Moscona (1921-2009) and Alberto Monroy (1913-1986) in 1966, a two-volume set of CTDB (volumes 116 and 117), entitled Essays on Development, will be published by Academic Press/Elsevier in early 2016.á The volumes are edited by Paul M. Wassarman, series editor of CTDB, and include contributions from dozens of outstanding developmental biologists from around the world.á Overall, the essays provide critical reviews and discussion of developmental processes for a variety of model organisms.á Many essays relate the history of a particular area of research, others personal experiences in research, and some are quite philosophical.á Essays on Development provides a window onto the rich landscape of contemporary research in developmental biology and should be useful to both students and investigators for years to come.Covers the area of developmental processes for a variety of model organismsInternational board of authors Part of two 50th Anniversary volumes proving a comprehensive set of reviews edited by Serial Editor Paul M. Wassarman

Chemokines, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in chemokines, and includes sections on such topics as chemokine detection using receptors, tracking cellular responses to chemokines, recognition of GAG-bound chemokines, and the production of chemokine receptor complexes for structural and biophysical studies.Continues the legacy of this premier serial with quality chapters authored by leaders in the fieldCovers research methods in chemokinesContains sections on such topics as chemokine detection using receptors, tracking cellular responses to chemokine, recognition of GAG-bound chemokines, and the production of chemokine receptor complexes for structural and biophysical studies