Bøker utgitt av Elsevier Science Publishing Co Inc

Presents the evidence of this theory, demonstrating the biogeographic approach to Australia's megafauna extinction. This book examines future climate change and its effects on the planet by looking at examples buried in the past. It presents an evidence from extensive field research.

Covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This title focuses on the clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products and also addresses the advances in the field.

Covers our understanding of the role of mesenchymal stem cells (MSCs) and other mesenchymal progenitors in skeletal regeneration, encompassing bone, cartilage and whole joint regeneration. This book provides a short historical 'detour' and foundational information on founding concepts, discoveries and personalities in MSC research.

Contains 60 quality 2D NMR data sets following an introductory section describing the methodology employed. This title presents strategies for assigning resonances to known structures and for deducing structures of unknown organic molecules based on their NMR spectra.

The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. . Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development.

Human Inspired Dexterity in Robotic Manipulation provides up-to-date research and information on how to imitate humans and realize robotic manipulation. Approaches from both software and hardware viewpoints are shown, with sections discussing, and highlighting, case studies that demonstrate how human manipulation techniques or skills can be transferred to robotic manipulation. From the hardware viewpoint, the book discusses important human hand structures that are key for robotic hand design and how they should be embedded for dexterous manipulation. This book is ideal for the research communities in robotics, mechatronics and automation.

The fundamental concept of The Biology and Identification of the Coccidia (Apicomplexa) of Carnivores of the World is to provide an up-to-date reference guide to the identification, taxonomy, and known biology of apicomplexan intestinal and tissue parasites of carnivores including, but not limited to, geographic distribution, prevalence, sporulation, prepatent and patent periods, site(s) of infection in the definitive and (if known) intermediate hosts, endogenous development, cross-transmission, pathology, phylogeny, and (if known) their treatments. These data will allow easy parasite recognition with a summation of virtually everything now known about the biology of each parasite species covered. The last (very modest) and only treatise published on this subject was in 1981 so this book fills a fundamental gap in our knowledge of what is now known, and what is not, about the coccidian parasites that infect and sometimes kill carnivores and/or their prey that can harbor intermediate stages, including many domestic and game animals.