Bøker utgitt av Elsevier Science Publishing Co Inc

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy.Presents the most advanced information regarding the role of the autophagic system in life and death Contains a direct focus on the role of a novel binuclear palladacycle complex that inhibits melanoma growthIntroduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammationStates recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalitiesEdited work with chapters authored by leaders in the field from around the globe-the broadest, most expert coverage available

Linked by Blood: Hemophilia and AIDS recounts the factors responsible for the widespread infection of people with hemophilia by Human Immunodeficiency Virus (HIV)-contaminated blood and offers a prescription for addressing the challenges of future viral epidemics. The book describes the impact of AIDS on people with hemophilia, their families, and caregivers. The collection, processing, and distribution of blood in the early years of the HIV epidemic are described, including the failure of regulatory agencies to promulgate effective rules to safeguard the blood supply. The contributions of individuals and organizations that mitigated the epidemic are recognized. Linked by Blood presents recommendations for addressing the myriad medical, social, and economic challenges posed by blood-borne viral infections (AIDS, Ebola, MERS) that periodically sweep through large segments of our population.Addresses the challenges of future viral epidemicsPromotes understanding of the risks and benefits of blood transfusionDemystifies HIV/AIDS by explaining how the virus causes disease and is detected and treatedCovers the factors that led to contamination of the blood supply and contributed to the AIDS epidemicProvides background information on hemophilia: who is affected, why they bleed, how it is treated, and what complications can occurDiscusses the role of regulatory agencies in protecting the blood supply and ensuring the safety of blood and blood productsFeatures new proposals to enhance blood product safety and regulate the prices of blood, drugs, and devices that are essential for human health

Mustard Lung: Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients brings together the details regarding pathophysiology, medication, and protective issues to provide a comprehensive look at health problems associated with sulfur mustard injury. It provides a bench-to-bedside look at the long term complications of vesicant exposure in humans as well as how mustard gas exposure affects lung function. By providing guidelines and approaches for the diagnosis, pathogenesis, and treatment of SM injury cases, this book is helpful for a wide range of medical researchers and clinicians. For decades, chemical respiratory disorders were diagnosed and managed traditionally similar to other chronic respiratory diseases. However, the exact nature of chemical respiratory disorders is different and needs to be treated as such. Includes the most up-to-date basic and clinical research findings on sulfur mustard from top researchersProvides information on chemical agents, complications that arise due to sulfur mustard exposure, and drugs available to treat injuriesContains an appendix with practical prescription recommendations for patients affected by mustard lungProvides a bench-to-bedside look at the long term complications of vesicant exposure in humans as well as how mustard gas exposure affects lung function

Host-Microbe Interactions, the latest volume in the Progress in Molecular Biology series, provides a forum for the discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their respective fields, along with abundant references. This volume is dedicated to the subject of host-microbe interactions.Provides the latest research on host-microbe interactions, including new discoveries, approaches, and ideasContains contributions from leading authorities on topics relating to molecular biologyInforms and updates on all the latest developments in the field

Computational Approaches for Studying Enzyme Mechanism Part A, is the first ofá two volumes in the Methods in Enzymology series, focusses on computational approaches for studying enzyme mechanism. The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, and genetics to name a few.Focusses on computational approaches for studying enzyme mechanismContinues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in intermediate filament associated proteins, and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers

Genetics, Genomics and Fish Phenomics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions, with hhis volume focusing on genetics, genomics, and phenomics of fish.Includes a critical analysis of future directions for the study of clinical genetics Written and edited by recognized leaders in the field Presents new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics

Logarithmic Image Processing: Theory and Applications, the latest volume in the series that merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy and features cutting-edge articles on recent developments in all areas of microscopy, digital image processing, and many related subjects in electron physics. Merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy into a single volumeContains the latest information on logarithmic image processing and its theory and applicationsFeatures cutting-edge articles on recent developments in all areas of microscopy, digital image processing, and many related subjects in electron physics

In boiler furnace, there are four physical and chemical processes at the same time and same place, combustion, flow, heat transfer and mass transfer. This book covers all the typical boilers with most of the fuels. It describes the basic theory with real design, especially those basing on the meaningful experimental data and knowledge in practice.

Phenotyping Crop Plants for Physiological and Biochemical Traits presents a proven range of methodologies and practices for effective, efficient, and appropriate typing of crop plants. By addressing the basic principles and precautions needed when conducting crop-based experiments, this book guides the reader in selecting the appropriate method based on the growing environment, whether greenhouse, pot, field, or liquid (hydroponic). By addressing the quantification of seed traits related to growth experiments, including their viability and vigor, this book presents methodology options for optimum yield based on potential abiotic stresses.

Management of Hemostasis and Coagulopathies for Surgical and Critically Ill Patients: An Evidence-Based Approach offers a concise guide to a sub-specialty of transfusion medicine from the clinical laboratory perspective. It focuses on the clinical tests that may be done during preoperative assessment, intraoperative, and postoperative assessment and management of surgical or critically ill patients. Management of hemostasis and coagulopathies is approached from an evidence-based perspective¿the coagulation status of a patient according to the laboratory test results. Algorithms and decision-support software, designed by the authors, guide clinicians with an additional tool to base transfusion dosage on specific laboratory results, including the use of an artificial neural network for predicting more accurate blood use. Chapters reflect the experience of all three authors who have successfully applied the algorithm for better patient management as well as decreased wastage of expensive blood products, from both the clinical laboratory/pathology and clinical medicine perspective. This book will appeal to a broad section of clinical laboratory and medical practitioners from hematopathology, to internal medicine, surgery, and anesthesiology. For hematopathologists and pathologists who are involved in laboratory medicine and transfusion medicine, this book will help them understand the proper utilization of blood products and how to avoid unnecessary waste and costs for the hospital. For general surgery practitioners, this book will provide practical guidelines on how to use blood products rationally for best medical practice. Internists will also gain insight from this book, learning which patients are at higher risk of bleeding during surgery so that they can alert their clinical colleagues.