Bøker utgitt av Elsevier Science Publishing Co Inc

Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field.

Invertebrate Embryology and Reproduction deals with the practical and theoretical objectives of the descriptive embryology of invertebrates, along with discussions on reproduction in these groups of animals. It explains several morphological and anatomical expressions in the field and covers the embryology of invertebrate animals, starting from the Protozoa, to the Echinodermata, the Protochordate and Tunicates. These groups include economically important aquatic invertebrates, such as crustaceans, as well as medically important invertebrates and economic arthropods. Each chapter is preceded by the taxonomy of the discussed phylum and/or the species to enable the reader to locate the systematic position.

Exchange-Traded Funds in Europe provides a single point of reference on a diverse set of regional ETF markets, illuminating the roles ETFs can play in risk mitigation and speculation. Combining empirical data with models and case studies, the authors use diffusion models and panel/country-specific regressions-as well as graphical and descriptive analyses- to show how ETFs are more than conventional, passive investments. With new insights on how ETFs can improve market efficiency and how investors can benefit when using them as investment tools, this book reveals the complexity of the world's second largest ETF market and the ways that ETFs are transforming it.