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RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics.

Electrophysiology Measurements for Studying Neural Interfaces helps readers to choose a proper cell line and set-up for studying different bio-electronic interfaces before delving into the electrophysiology techniques available. Therefore, this book details the materials and devices needed for different types of neural stimulation such as photoelectrical and photothermal stimulations. Also, modern techniques like optical electrophysiology and calcium imaging in this book provides readers with more available approaches to monitor neural activities in addition to whole-cell patch-clamp technology.

Cognitive Biases in Health and Psychiatric Disorders: Neurophysiological Foundations focuses on the neurophysiological basis of biases in attention, interpretation, expectancy and memory. Each chapter includes a review of each specific bias, including both positive and negative information in both healthy individuals and psychiatric populations. This book provides readers with major theories, methods used in investigating biases, brain regions associated with the related bias, and autonomic responses to specific biases. Its end goal is to provide a comprehensive overview of the neural, autonomic and cognitive mechanisms related to processing biases.

How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease.

The Cognitive Approach in Cloud Computing and Internet of Things Technologies for Surveillance Tracking Systems discusses the recent, rapid development of Internet of things (IoT) and its focus on research in smart cities, especially on surveillance tracking systems in which computing devices are widely distributed and huge amounts of dynamic real-time data are collected and processed. Efficient surveillance tracking systems in the Big Data era require the capability of quickly abstracting useful information from the increasing amounts of data. Real-time information fusion is imperative and part of the challenge to mission critical surveillance tasks for various applications. This book presents all of these concepts, with a goal of creating automated IT systems that are capable of resolving problems without demanding human aid.

Historical Ethnobiology presents a unique approach to analyzing human-nature interactions, using theoretical and methodological aspects to examine historical scientific knowledge. This book disseminates the notion that past local narratives of biodiversity influence the determination of both historical and modern scientific decisions. Beginning with a brief history of ethnobiology¿s development, this book delves into conceptual models, historical knowledge areas, and the theoretical matrix of ethnobiology. This book also focuses on the importance of memory including topics of memory production by human in different epochs and how individual memory records contribute to social history and the understanding of the past effects of human interaction with nature. Looking ahead, it discusses the importance of records such as these for determining future mankind¿s relationships with nature to preserve biodiversity and ensure conservation. Historical Ethnobiology is the first book to focus on past human-nature interactions and their interpretations in today¿s scientific culture. This book is an excellent resource for students and researchers in biology, ethnobiology, and anthropology.

This book draws together, for the first time, the published research on the behaviour, ecology and welfare of elephants living in zoos, circuses, logging camps and other captive environments in a single comprehensive volume. It takes a multi-disciplinary approach, considering the work of zoo biologists, animal behaviour and welfare scientists, veterinarians, philosophers, zoo educators, tourism specialists, conservation biologists, lawyers and others with a professional interest in elephants. Elephants under Human Care: The Behaviour, Ecology, and Welfare of Elephants in Captivity is a valuable resource for zoo biology and animal welfare researchers. It is also useful for students and zoo professionals and managers looking for a comprehensive guide to current research on captive elephants. Although not intended as a husbandry manual, the book discusses some of the elephant welfare standards developed by the Association of Zoos and Aquariums (AZA) and the British and Irish Association of Zoos and Aquariums (BIAZA) and their relationship to current knowledge of captive elephants.

The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters

Estimation of the Time Since Death is a current comprehensive work on the methods and research advances into the time since death and human decomposition. This work provides practitioners a starting point for research and practice to assist with the identification and analysis of human remains. It contains a collection of the latest scientific research, various estimation methods, and includes case studies, to highlight methodological application to real cases. This reference first provides an introduction, including the early postmortem period, biochemical methods, and the value of entomology in estimating the time since death, along with other factors affecting the decomposition process. Further coverage explores importance of microbial communities in estimating time since death. Separate chapters on aquatic environments, carbon 14 dating and amino acid racemization, and total body scoring will round out the reference. The final chapter ties together the various themes in the context of the longest running human decomposition facility in the world and outlines future research directions.

Risk Factors for Psychosis: Paradigms, Mechanisms, and Prevention combines the related, but disparate research endeavors into a single text that considers all risk factors for psychosis, including biological, psychological and environmental factors. The book also introduces the ethics and current treatment evidence that attempts to ameliorate risk or reduce the number of individuals with risk factors developing a psychotic disorder. Finally, the book highlights new research paradigms that will further enhance the field in the future. Psychotic disorders affect more than 50 million people worldwide, creating a devastating effect on lives and causing major financial and emotional impact on families and on society as a whole. The search for risk factors for psychosis has developed rapidly over the past decades, invigorated by changes in the thinking about the malleability and treatability of psychotic disorders. The paradigms for investigating psychosis risk have developed, often in parallel, but there has been no book to date that has summarized and synthesized the current approaches.

Supervised Machine Learning in Wind Forecasting and Ramp Event Prediction provides an up-to- date overview on the broad area of wind generation and forecasting, with a focus on the role and need of Machine Learning in this emerging field of knowledge. Various regression models and signal decomposition techniques are presented and analyzed, including least-square, twin support and random forest regression, all with supervised Machine Learning. The specific topics of ramp event prediction and wake interactions are addressed in this book, along with forecasted performance. Wind speed forecasting has become an essential component to ensure power system security, reliability and safe operation, making this reference useful for all researchers and professionals researching renewable energy, wind energy forecasting and generation. Features various supervised machine learning based regression modelsOffers global case studies for turbine wind farm layoutsIncludes state-of-the-art models and methodologies in wind forecasting

Industrial Enzymes for Biofuels Production: Recent Updates and Future Trends focuses on resolving existing bottlenecks in enzymes mediated biomass to biofuels production processes through updating recent scientific knowledge and technology developments. The book provides low cost sustainable approaches to lower the cost of enzymes production following different approaches. It is specifically focused on industrial aspects of enzymes used in biofuels production processes by presenting in-depth study of existing issues related to practical viability and long-term sustainability. The book covers detailed discussions on market scenario of industrial enzymes used in biofuels production processes and compares them on both lab and industrial scale. Users will find this to be a great resource that also helps them develop low cost green technologies for enzyme development in biofuels production. Includes recent updates in research and the technologies of industrial enzymes used in biofuels production processDescribes various developed low-cost technologies for enzyme productionExplores different, sustainable approaches currently being used

Atmospheric Satellite Observations: Variation Assimilation and Quality Assurance provides an invaluable reference for satellite data assimilation. Topics covered include linear algebra, frequently used statistical methods, the interpolation role of function fitting, filtering when dealing with real observations, minimization in data assimilation systems, 3D-Var and the inverse problem it solves, 4D-Var and adjoint techniques, and much more. The book concludes with satellite observation of hurricanes. Contains mathematical concepts from several branches of study, including calculus, linear algebra, probability theory, functional analysis, and minimizationIllustrates quality assurance for satellite observations using real data examplesIncludes a dedicated chapter on how different satellite instruments see hurricanesReviews theory, system development, and the numerical experiments of three- and four-dimensional variational data assimilation (3D-Var/4D-Var)

Quaternary Ecology, Evolution, and Biogeography offers an introduction to the study of the ecological and evolutionary processes that have shaped our present biosphere under the influence of glacial-interglacial cycles. Written by an ecologist with paleoecological expertise, this book reviews the climactic changes that have occurred during the last 2.6 million years, along with the responses of organisms and ecosystems. It offers an understanding of the evolutionary origin of extant biodiversity, its biogeographical patterns, and the composition of modern ecological communities. In addition, it explores human evolution and the influence of our activities on the biosphere, especially in the last millennia. This book offers the latest information on how studying the past can contribute to our understanding of present climate issues for a better future, and is an ideal resource for researchers and students in the natural sciences. Includes the latest developments in genomics and their relevance within Quaternary evolutionOffers a holistic view of the origin of biodiversity patterns and community assemblyDiscusses the role of climate on human evolution and the ecological consequences for natural systems

A Beginners Guide to Data Agglomeration and Intelligent Sensing provides an overview of the Sensor Cloud Platform, Converge-casting, and Data Aggregation in support of intelligent sensing and relaying of information. The book begins with a brief introduction on sensors and transducers, giving readers insight into the various types of sensors and how one can work with them. In addition, it gives several real-life examples to help readers properly understand concepts. An overview of concepts such as wireless sensor networks, cloud platforms, and device-to-cloud and sensor cloud architecture are explained briefly, as is data gathering in wireless sensor networks and aggregation procedures. Final sections explore how to process gathered data and relay the data in an intelligent way, including concepts such as supervised and unsupervised learning, software defined networks, sensor data mining and smart systems. Presents the latest advances in data agglomeration for intelligent sensingDiscusses the basic concepts of sensors, real-life applications of sensors and systems, the protocols and applications of wireless sensor networks, the methodology of sensor data accumulation, and real-life applications of Intelligent Sensor NetworksProvides readers with an easy-to-learn and understand introduction to the concepts of the cloud platform, Sensor Cloud and Machine Learning