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Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. The updates to the Third Edition include a new section converting "descriptive" data into "predictive" data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug-drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

Computer Vision and Machine Intelligence for Renewable Energy Systems offers a practical, systemic guide to the use of computer vision as an innovative tool to support renewable energy integration.This book equips readers with a variety of essential tools and applications: Part I outlines the fundamentals of computer vision and its unique benefits in renewable energy system models compared to traditional machine intelligence: minimal computing power needs, speed, and accuracy even with partial data. Part II breaks down specific techniques, including those for predictive modeling, performance prediction, market models, and mitigation measures. Part III offers case studies and applications to a wide range of renewable energy sources, and finally the future possibilities of the technology are considered. The very first book in Elsevier’s cutting-edge new series Advances in Intelligent Energy Systems, Computer Vision and Machine Intelligence for Renewable Energy Systems provides engineers and renewable energy researchers with a holistic, clear introduction to this promising strategy for control and reliability in renewable energy grids.

Greening Our Economy for a Sustainable Future examines the green economy by balancing social needs, the environment, and the economy. It argues that different economic models must be developed to address the environment caused by economic expansion. The book not only looks at the opportunities of having a green economy, but also goes into areas such as greenwashing, social washing, sustainability, economics, and more. In addition, it addresses how one can improve well-being through a symbiotic relationship between economic growth and environmental stewardship.

Artificial Intelligence for Subsurface Characterization and Monitoring provides an in-depth examination of how deep learning accelerates the process of subsurface characterization and monitoring and provides an end-to-end solution. In recent years, deep learning has been introduced to the geoscience community to overcome some longstanding technical challenges. This book explores some of the most important topics in this discipline to explain the unique capability of deep learning in subsurface characterization for hydrocarbon exploration and production and for energy transition. Readers will discover deep learning methods that can improve the quality and efficiency of many of the key steps in subsurface characterization and monitoring. The text is organized into five parts. The first two parts explore deep learning for data enrichment and well log data, including information extraction from unstructured well reports as well as log data QC and processing. Next is a review of deep learning applied to seismic data and data integration, which also covers intelligent processing for clearer seismic images and rock property inversion and validation. The closing section looks at deep learning in time lapse scenarios, including sparse data reconstruction for reducing the cost of 4D seismic data, time-lapse seismic data repeatability enforcement, and direct property prediction from pre-migration seismic data.

Advances in Ophthalmology and Optometry reviews the year’s most important findings and updates within the field in order to provide ophthalmologists and optometrists with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Dr. Myron Yanoff, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in ophthalmology and optometry inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care.Contains 30 articles on such topics as visual snow syndrome; current management of nystagmus; same-day bilateral cataract surgery; management of dislocated IOLs; distinguishing papilledema from pseudopapilledema; multidisciplinary orbital tumors; periocular aesthetics; and more.Provides in-depth, clinical reviews in ophthalmology and optometry, providing actionable insights for clinical practice.Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Advancements in Nanotechnology for Food and Packaging explores current trends, advances and associated challenges of the applications of nanotechnology in the food sectors, such as the fabrication and characterization of functional food, developments and shelf-life extension. This book is organized into 16 chapters that cover the main concepts related to the use of nanotechnology in food processing, packaging and monitoring. Coverage includes food functionalization, quality management and control, food sensory, membrane filtration technology, nanotechnology-based sensors, sustainable packaging, regulatory aspects, and much more. This book an essential resource for materials and food scientists, technologists, researchers, academics and professionals working in nanotechnology and food science.

PEM Water Electrolysis: Fundamentals and Practice is a comprehensive reference on the design and operation of PEM water electrolyzers. Combining hydrogen production with engineering thermophysics, the book provides a unique resource for understanding the hydrogen production process, from fundamental concepts to practical implementation. Divided into four parts, the book covers the current state of hydrogen and the fundamentals of PEM water electrolysis and the various components and materials used in PEM electrolysis, including electrocatalysts, proton exchange membranes, membrane electrode assembly, porous transport layer, flow field, and corrosion, and more. Other sections explain the key processes involved in PEM electrolysis, such as two-phase flow, heat and mass transfer and delve into systems research, covering grid fluctuations, control systems, assembly, diagnosis, and commercialization. In addition, the book provides comprehensive information on the modeling of PEM electrolyzers, including heat and mass transfer and system analysis. Finally, the book contains informative videos of industrial facilities, laboratory setups, and preparation procedures.

Clinical Reasoning and Decision-Making Process: Child and Adolescent Assessment and Intervention presents an in-depth analysis by experienced psychologists on how to engage in clinical reasoning and decision making from assessment to intervention with children and youth. This book emphasizes the importance of using and articulating clinical reasoning within a well-defined framework and its goal in guiding diagnostic and treatment decisions. This book encourages critical thinking including reflection, judgment, inference, problem solving, and decisionmaking based on the interaction of efficient and effective clinical judgment and truth-seeking accountability.With a primary goal of providing examples of processes and procedures, this book validates and enriches the importance of clinical reasoning and decision making in psychology.

Renewable Energy for Plug-In Electric Vehicles: Challenges, Approaches, and Solutions for Grid Integration provides a holistic guide to the critical technical challenges of integrating renewable energy for grid-connected electric vehicles. Considering the impact of renewable energy integration from a wide range of perspectives, this book leverages its global range and expertise to cover problems from power stability to market strategies, fast charging, and cybersecurity. Practical solutions are provided, incorporating the latest advances in technologies across meters, sensors, batteries, storage, demand response, artificial intelligence, and power system design. Supporting broad understanding and practical solution development, the book enables researchers, students, and industry professionals to take the next steps towards renewably sourced, grid-integrated electric vehicles.

Dynamic Relationality Theory of Creative Transformation: Grounding Machinic Ecosystems in Life Experiences introduces a visionary approach to understanding the evolving relationship between technology and human experiences. It delves into the transformative potential of Machinic Generalized Intelligence (MGI), where AI and human intelligence converge harmoniously, creating a new paradigm of interactive, machinic life experiences. This book challenges the traditional tech-centric view, advocating for a life and experience-first perspective. It presents the Dynamic Relationality Theory (DRT), a novel conceptual framework that redefines our interaction with technology, emphasizing cocreative, emergent experiences over mere digital platformization.Through an interdisciplinary approach combining philosophical insights and social theories with practical applications, this book navigates the complexities of digitalized life ecosystems, employing concepts and tools from assemblage theory, category theory, sheaf theory, differential topology, and gauge theory. For readers grappling with the complexities of AI and its societal implications, this book offers clarity and direction. It provides a robust theoretical framework to understand the changing landscape of human-technology interaction. Furthermore, it integrates philosophical insights and ethical considerations into the discussion of AI and technology, providing a well-rounded perspective that aids in ethical decision-making and responsible innovation. It also delves into practical applications and future implications of AI, aiding readers in applying these concepts in real-world scenarios.By moving beyond a purely technological focus, this book equips readers with the insights needed to navigate the ethical, philosophical, and practical challenges posed by the integration of AI into daily life. A crucial resource for academics, professionals, and policymakers, this book serves as a guide to making informed decisions and fostering responsible innovation in the age of AI.

Federated Learning for Medical Imaging: Principles, Algorithms and Applications gives a deep understanding of the technology of federated learning (FL), the architecture of a federated system, and the algorithms for FL. It shows how FL allows multiple medical institutes to collaboratively train and use a precise machine learning (ML) model without sharing private medical data via practical implantation guidance. The book includes real-world case studies and applications of FL, demonstrating how this technology can be used to solve complex problems in medical imaging. In addition, it provides an understanding of the challenges and limitations of FL for medical imaging, including issues related to data and device heterogeneity, privacy concerns, synchronization and communication, etc. This is a complete resource for computer scientists and engineers as well as clinicians and medical care policymakers wanting to learn about the application of federated learning to medical imaging.

Smart Cities and Sustainable Manufacturing: Innovations for a Greener Future explores the intersection of these two essential disciplines, underscoring the transformative potential of their integration in sculpting sustainable urban landscapes. By providing cutting-edge research, case studies, success stories, and practical guidance, this book facilitates knowledge sharing and collaboration and inspires stakeholders to implement sustainable and innovative solutions. Further, it illustrates how integrating smart cities and sustainable manufacturing can contribute to a greener future by investigating the role of emergent technologies, policy frameworks, business models, and more.This essential resource covers a range of topics related to smart cities and sustainable manufacturing, including technologies for smart cities, such as IoT, AI, big data analytics, and sensor networks; sustainable infrastructure design, such as green buildings, energy-efficient transportation systems, and renewable energy integration; circular economy and waste management strategies; sustainable transportation initiatives such as intelligent transportation systems, electric mobility solutions, and shared mobility services, and much more.

Accelerating Digital Transformation with the Cloud and the Internet of Things (IoT) is a reference for IT engineers and decision-makers who may engage in IoT platform pilot projects. The resources covered in this book help establish plans for sustainable operations and management and assist with the long-term procurement of relevant IoT technologies. The aim of the book is to be exhaustive and holistic by pointing out numerous issues and related solution options that guide with daily challenges when deploying and running IoT platforms. The book is divided into three parts where each part includes relevant theoretical chapters and applied case studies. Part One focuses on architectural and federation options for the design and implementation of IoT platforms that foster strategic collaboration opportunities. Part Two addresses vertical security challenges across IoT platform layers. Finally, Part Three shows how IoT is driving the digital transformation wheel through existing and forthcoming case studies.

Distributed Energy Storage Systems for Digital Power Systems offers detailed information of all aspects of distributed energy resources and storage systems, and their integration into modern, digital power systems, supporting higher power systems operational flexibility towards 100% renewable energy integration. Covering fundamentals, analysis, design, and operation, and supported by examples and case studies, the book also examines many new advances in terms of distributed energy storage systems for DER integration, dynamically varying loads of EV charging stations, power quality enhancements, and ancillary services. This is a valuable resource for researchers, scientists, and graduate students in energy storage, renewable energy, power systems, and engineering, as well as engineers, R&D, and other industry personnel working with renewable energy systems, energy storage, demand response, and microgrids.

Photothermal Materials and Membranes for Solar-Driven Water Treatment provides a comprehensive understanding of the chemistry of different photothermal materials, mechanistic pathways for light-to-heat energy conversion, design, and development of various 3D evaporation systems configurations, and photothermal membranes for water treatment. The book contributes to the understanding of photothermal materials to system design for efficient solar-to-heat conversion and solar-steam generation and paves the way forward to meet increasing freshwater demand through a sustainable and environmentally friendly approach. The book provides an in-depth introduction to emerging concepts such as steam generation; gives the basics of solar light and solar-light-adsorbing materials’ function, efficiency, and applications; discusses the preparation of photothermal materials and membranes; analyzes the key characteristic properties of photothermal materials; elaborates on water evaporation using nature-inspired system design; and highlights the key commercialization approaches and technologies. This book is an excellent resource for chemical engineers, materials scientists, energy technologists, environmentalists, policymakers, and regulatory bodies working on water treatment, wastewater decontamination, photothermal materials and membranes, photocatalytic materials, membrane separation, and membrane filtration.

Microbiology and Health Benefits of Traditional Alcoholic Beverages is an interdisciplinary reference for students, researchers, and academics studying anthropology and food and beverage science, especially those with interest in fermentation. Fermented beverages and alcoholic drinks are culturally and socially accepted products for consumption, drinking, entertainment, as well as for customary practices and religious purposes. Due to variation in substrates, climatic conditions, geographical locations and ethnicity, a colossal diversity of microbial community as well as major domains have been reported in the different varieties of fermented beverages of the world. This book covers the cultural context of these beverages along with their biochemistry, health benefits, and therapeutic uses. Topics include winemaking, malting and brewing of wine and beer, and culturally specific beverages and practices such as fermented palm beverages and agave.

Equity, Diversity, and Inclusion in Healthcare: From Knowledge to Practice offers a comprehensive text on the landscape of equity, diversity, and inclusion (EDI) in the health professions. Each chapter is dedicated to a health profession and is authored by an expert in EDI and workforce diversity in their respective discipline (such as medicine, dentistry, nursing, pharmacy, physiotherapy, and so on). Chapters characterize the present state of workforce diversity in the discipline, chronicle historical developments, provide rationale for systemic action, and include possible solutions and interventions in an evidence-based manner. By serving as an all-in-one reference text, this resource is meant for students, healthcare professionals, and organizational leadership who wish to understand and implement EDI in the health professions.

Drug Delivery Systems for Wound Healing explores the different delivery systems and drugs used in wound healing, outlining the many pharmaceutical approaches in wound healing and management. Bringing together interdisciplinary research on wound healing and management, this book offers the theory behind wound healing, but also has a strong focus on the practical approach where scientists involved in medication development can find suggestions. Where appropriate, clinical outcomes are given so the book can be useful as a guide for the choice by medication prescription or use. Topics in the book include types of drugs used in wound healing; types of carriers used in wound healing; clinical outcomes; biocompatibility and toxicity problems, and pipeline products. Researchers working in the pharmaceutical sciences, biomedical sciences and engineering fields will find this a useful resource.

Characterization, Properties and Methods of Spent Nuclear Fuel is a comprehensive reference focused on the backend of the nuclear fuel cycle. It is paramount that researchers and engineers involved with spent fuel have a deep understanding of the specific fuel they are handling for both safety and economic reasons, and this book presents various opportunities to optimize both nuclear facilities and processes. It starts with a summary of the topic before presenting a broad and deep analysis of the methods available, including transport, storage, disposal, reprocessing, and accidents. Fuel characterization is then presented alongside various methods, measurements, codes and calculations which the reader can follow and apply to their own research or setting. With a focus on decision making and safety, this book will benefit all readers involved in spent nuclear fuel and will equip them with a clear understanding of the safest and most economical approaches which best suit their specific setting.

A New Systems Thinking Approach to Sustainable Resource Management: Principles and Applications introduces an innovative approach to exploring systems holistically and understanding complex interconnected dynamics effectively among technical systems, natural systems, and human activities to address challenges in resource management.This book covers the fundamental principles of "systems" and "sustainability", and introduces the methodology of "new systems thinking," which comprises system modeling, mapping, integration, analysis, and sustainability assessment. The application of this new systems thinking approach is demonstrated through practical case studies, including waste management systems, food-energy-water nexus, and biorefinery systems. This is an excellent reference for academics, undergraduate and postgraduate students, professional engineers, and policymakers across various disciplines including: chemical and process engineering, environmental science, environmental engineering, and environmental management.

High-Entropy Alloys: Design, Manufacturing, and Emerging Applications presents cutting-edge advances in the field of these materials, covering their mechanics, methods of manufacturing, and applications, all while emphasizing the link between their structure/microstructure and functional properties. The book starts with a section on the fundamentals of high-entropy alloys (HEAs), with chapters discussing their thermodynamics, subgroups (transition metal; refractory; ceramics; metallic glasses and more), physical metallurgy, and microstructural characterization. The next section features chapters which look at manufacturing processes of HEAs, such as liquid metallurgy synthesis, in-situ synthesis, additive manufacturing, machine learning, friction stir welding, and fabrication of coatings for HEAs. The final section of the book covers applications of these materials, including their use as irradiation-resistant structural materials, catalyst materials, electrode materials, HEAs for solid hydrogen storage, and more. The book is a key resource for academic researchers, grad students, and industry professionals working with HEAs across a range of disciplines and applications including aerospace, functional materials, catalyst materials, gas storage, sensing, super-conducting materials, biomedical, civil engineering, energy storage, and energy materials.

Enzyme Biotechnology for Environmental Sustainability discusses recent applications of enzyme biotechnology in various industrial sectors and state-of-the-art information on novel microbial enzyme technologies for a sustainable environment. The book describes in detail the latest developments and modern methods in microbial enzyme biotechnology for wider application in bioremediation, cleaner technology for industries and waste management, green chemistry and pharmaceutical biotechnology, sustainable textiles, food production and biodegradation, and other industries. The chapters cover topics such as genetic engineering, protein engineering, nanotechnological advances of microbial enzymes, computational tools for engineering enzymes, and health risk assessment of enzymes in different sectors. With contributors from an array of experts in the field, Enzyme Biotechnology for Environmental Sustainability is an informative reference for researchers, biotechnologists, microbiologists, environmental scientists, graduate and post-graduate students working in the area of enzyme technology and their biomedical, environmental, and industrial applications.

Low Cost Water and Wastewater Treatment Systems: Conventional and Recent Advances introduces different conventional and advanced low-cost systems for water and wastewater treatment. The technologies involve conventional biological processes with low-cost and newly developed processes for improving the performance of the treatment processes. The book also contains chapters describing some main topics which discusses their principles, development, and applications: 1) low-cost biological treatment system; 2) bioremediation technologies; 3) natural-based technologies; 4) biomedia-based technologies; 5) adsorption-based technologies; 6) membrane filtration-based technologies; and 7) emerging technologies. It investigates various low-cost treatment technologies and applies these to the removal of organic matters, nutrients, and emerging micro pollutants in developing countries and worldwide.

Quick Guide to Endocrinology, The Pediatric Version, Second Edition, continues to be an essential resource which focuses on the physiology, diagnostics, and laboratory testing of endocrine (hormone-mediated) disorders encountered in the field of endocrinology with expanded coverage of pediatric endocrinology. The guide is for laboratory scientists and technicians, as well as trainees and clinicians in the field of pediatrics and pediatric endocrinology including fellows, residents, medical students, nursing students, and advance practice providers and students. It is presented in an easy to read, quick format, the physiology and method of measurement for hormones essential to many bodily processes and how their dysregulation results in disease. The characteristics of such diseases and diagnostic testing including up-to-date molecular testing is addressed.

Translational Urology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in urology, and know what is needed for successful collaboration. Further, this title is an indispensable tool in grant writing and funding efforts.This practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in urology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care.

Alexander's Nursing Practice is the most comprehensive textbook available for undergraduate nursing students today. This resource will prepare students for their future role as healthcare professionals in a variety of settings. It covers all the basics of nursing, including care of patients with common disorders, core nursing issues like medicines management and infection prevention and control, and how to nurse specific patient groups. The sixth edition has been fully updated to incorporate the latest evidence, policies and registration requirements, and reflects the transformative changes currently occurring in healthcare policies, procedures and technologies. With a host of features to enhance the learning and teaching experience, this book will make a significant contribution to preparing compassionate nurses who will deliver patient-centred, high quality and holistic care. Designed to help the reader navigate the demands of the latest NMC educational requirementsExpert team of contributors led by renowned editor, Ian Peate OBE FRCNFully updated with the latest evidence and trends - incorporates the latest practice guidelines, research findings and clinical standards relevant to the nursing fieldAddresses the role of nurses in primary care settings, general practice nursing responsibilities, chronic disease management, health screening and the delivery of integrated, patient-centred care within the UK primary care landscapeRichly illustrated throughout to reinforce key concepts, demonstrate clinical procedures and engage students in active learningIncludes a wide range of helpful learning features including case studies and critical thinking exercises - helps the reader to analyse complex situations, make evidence-based decisions and communicate effectively with patients and healthcare team membersPedagogical features to help students navigate the textbook, organise their learning and review key concepts efficientlySupplemented with online material including MCQs, image bank, critical thinking questions, extra online material (supplementary text), website figure references and extra online imagesThe latest NHS policies, guidelines and protocols; aligned to NMC standards for nursing practice, Code of Professional Conduct and regulatory requirements for nursing education in the UKDiscussion of key legislation impacting nursing practice in the UK, such as the Health and Social Care Act, Mental Capacity Act, Data Protection Act and relevant provisions of the Human Rights Act, plus a special emphasis on the important issue of Duty of CandorConsideration of clinical governance frameworks, quality assurance mechanisms and risk management strategies implemented within the NHS to ensure patient safety, accountability and continuous improvement in healthcare deliveryEmphasises the importance of collaborative practice and interdisciplinary teamwork within the UK healthcare systemIntegration of content related to patient safety initiatives and strategies endorsed by organisations such as the National Patient Safety Agency (NPSA) and the NHS Patient Safety StrategyExpanded coverage of community and public health nursing roles, responsibilities and interventionsExplores mental health nursing practice within the UK contextEnhanced discussion around parity of health ensuring equity and fairness in the provision of healthcare services, regardless of individuals' socio-economic status, ethnicity, gender, age or other characteristics

If you’re writing a research proposal for the first time, this is the book for you. It’s the only text on the market that guides you through the entire process, from designing a research study to submitting a successful proposal. It covers everything from formulating the research question to selecting the research methodology, collecting data, and navigating ethics, all supported with plenty of practical tips, real life examples and checklists for honing your proposal. How to Design Studies and Write Research Proposals is written by nursing research expert Professor Kader Parahoo, whose work is loved by students for its accessible writing style and practical approach.Takes readers through all the steps of the research process from developing research questions to research impactDeals with quantitative, qualitative and mixed methods studiesProvides examples of real proposals, most of which are freely accessible onlineMakes reference to research studies and research proposals from a wide range of countriesProvides examples from the fields of nursing, allied health sciences and social workProvides detailed checklists of items to include in proposals, at the end of each chapterProvides useful references and links that readers can access to further explore issues raised in the text.Written in a language and style that makes research easier to understand

In this issue of Immunology and Allergy Clinics, guest editor Dr. Jenny Stitt brings her considerable expertise to the topic of Urticaria and Angioedema. Top experts focus on pathophysiology, guidelines-based treatments, and emerging treatments, with coverage of inducible urticarias; urticaria: impact on quality of life and economic cost; acquired angioedema; therapeutics for hereditary angioedema: on-demand and prophylactic; and more.Contains 13 relevant, practice-oriented topics including chronic spontaneous urticaria: etiology and pathogenesis; emerging therapeutics in chronic urticaria; emerging therapeutics in hereditary angioedema; and more.Provides in-depth clinical reviews on urticaria and angioedema, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Préparez-vous à la pratique avec ce texte essentiel consacré aux questions juridiques et éthiques canadiennes ! Axé uniquement sur l'environnement en constante évolution et souvent complexe des soins de santé au Canada, Questions éthiques et juridiques dans le secteur des soins infirmiers au Canada, 5e édition couvre de manière experte les questions éthiques et juridiques souvent entremêlées auxquelles les professionnels des soins de santé sont confrontés aujourd'hui. Cette édition comprend des discussions sur les perspectives juridiques et éthiques autochtones, les défis juridiques et éthiques liés au SRAS-CoV-2, des études de cas pour le NCLEX de nouvelle génération (NGN)®, et bien plus encore. De plus, le style d'écriture clair et direct présente l'information telle que vous la rencontrerez dans votre pratique quotidienne, ce qui vous assure d'être encore mieux préparé à avoir un impact dès le début !MISE À JOUR ! Cette version entièrement révisée et élargie couvre les sujets éthiques et juridiques les plus importants concernant les populations vulnérables, les autochtones (Rapport d'enquête Joyce Echaquan), les réfugiés et les personnes 2ELGBTQI+, les technologies de pointe et la télémédecine, l'évolution des champs d'exercice des différentes catégories d'infirmières, l'aide médicale à mourir (AMM) et bien d'autres encore. NOUVEAU ! Couverture des perspectives juridiques et éthiques indigènes et des modes de connaissance et de compréhension liés à la santé, aux soins de santé et à la prise de décision. NOUVEAU ! Informations actualisées sur les défis juridiques et éthiques à l'époque du SRAS-CoV-2. NOUVEAU ! Études de cas pour le NCLEX de nouvelle génération (NGN)®/MD sur le site Evolve.

In this issue of Neuroimaging Clinics, guest editors Drs. Frederik Barkhof and Yaou Liu bring their considerable expertise to the topic of Multiple Sclerosis and Associated Demyelinating Disorders. Top experts in the field discuss advanced brain imaging in CNS demyelinating diseases; new imaging markers in MS and related disorders: smoldering inflammation and central vein sign; the use of AI in MS and white matter disease; optic nerve imaging in MS and related disorders; atypical demyelinating disorders; and more. Co-Editor Frederik Barkhof, MD, has received the National Multiple Sclerosis Society and the American Academy of Neurology’s 2018 John Dystel Prize for Multiple Sclerosis Research for his many years of outstanding research in the field of MS, especially in advancing the understanding and clinical use of brain imaging.Contains 12 relevant, practice-oriented topics including diagnostic criteria for MS, NMOSD and MOGAD; routine MRI protocol and standardization in CNS demyelinating diseases; spinal cord imaging in MS and related disorders; treatment monitoring in MS: efficacy and safety; cognitive impairment in MS and related disorders; and more.Provides in-depth clinical reviews on multiple sclerosis and associated demyelinating disorders, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.