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Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. The eighth volume of the book features reviews on these topics: - Key data management elements in clinical trials for oncological therapeutics- Prospects for therapeutic targeting of microRNAs in brain tumors- Breast cancer vaccines: current status and future approach- Desmocollin-3 and cancer- MDM2-p53 antagonists under clinical evaluation: a promising cancer targeted therapy for cancer patients harbouring wild-type tp53- Towards targeted therapy: anticancer agents targeting cell organelle mitochondria- Anticancer therapeutic strategies in gliomas: chemotherapy, immunotherapy, and molecularly targeted therapy in adults

Advances in technology have enabled medicinal chemists to discover and formulate several highly specific, biocompatible, and non-toxic therapeutic agents for clinical applications. Nanotechnology has achieved significant progress in the last few decades and is crucial in every field of science and technology. Nanotechnology-based pharmaceuticals offer multifaceted and alternative methodologies in comparison to the limitations of many conventional clinical therapies. Expertise in designing and developing nanoformulations has helped in targeted drug delivery. Recently, the use of innovative therapeutic agents, particularly in nanomedicine, has accounted for a significant portion of the global pharmaceutical market and is predicted to continue to grow rapidly in the near future. Nanotherapeutic Strategies and New Pharmaceuticals is an accessible multi-part reference which informs the reader about several new techniques based on nanotechnology. The chapters explain relevant topics in detail. The book is designed to encourage and help undergraduate, graduate and post-graduate students in the field of nanotherapeutics, pharmaceuticals and bio-organic chemistry through the use of didactic language and simple illustrations.Part 1 of this book set explains general advances in nanomedicine, followed by chapters covering the role of nanotherapeutics in hematology and cancer treatment, as well as specific types of nanomaterials based on different components (such as boron, graphene, silver and other metals). The book also features a chapter that summarizes the processes for designing nanoparticles tailored for specific targets. The book serves as a textbook for students in pharmacology and medical biochemistry, as well as a quick reference for researchers on bio-organic chemistry, as well as general readers interested in nanomedicine.

This reference presents comprehensive information about laser surface treatments for tribological applications. Chapters of the book highlight the importance of laser technology in modifying materials to optimize the effects of friction and lubrication, by explaining a range of surface modification methods used in industries. These methods include hardening, melting, alloying, cladding and texturing. The knowledge in the book is intended to give an in-depth understanding about the role of laser technology in tribology and the manufacture of industrial materials and surfaces for special applications. Key Features: - 10 chapters on topics relevant to tribology and industrial applications of laser material processing- Comprehensively covers laser surface modification of metals and alloys- Explains a wide range of surface modification methods (hardening, melting, alloying, cladding and texturing)- Covers material and tribological characterization of surfaces- Presents information in a simple structured layout for easy reading, with introductory notes for learners- Provides references for further reading

Scientific literature on SARS-COV-2 viruses and its variants (especially variants of concern such as the 'Delta variant') and important cellular targets is crucial to help researchers, epidemiologists, virologists and clinicians around the globe to develop a new generation of safer and more effective vaccines, and other treatments to address COVID-19 disease. The accompanying damage to the many organs and tissues of SARS-Co-2-infected people also needs to be understood and researchers are using data to devise meaningful protocols for treating these symptoms. This second volume of Coronaviruses brings together more useful information about the prevention, vaccination, and chemotherapies for the potential treatment of coronavirus infections. The volume includes eight chapters: (1) Broad spectrum antivirals to combat COVID-19 The reality and challenges, (2) COVID-19: Preventive and protective control management strategies, (3) Plant-derived extracts and bioactive compounds against coronavirus progression: preventive effects, mechanistic aspects, and structures, (4) Gastroenteritis: symptoms and epidemiology of SARS-CoV-2, (5) The chronicles of coronavirus: A Chinese king who conquered the entire world, (6) Traditional medicine as a natural remedy in ARDS & COVID-19, (7) Molecular pathogenesis of human coronaviruses of the 21st century, (8) COVID-19, mental health and neuropathophysiology of pain related to temporomandibular disorder. The volume serves as a novel compilation of key data on SARS-CoV-2 and COVID-19 and represents a resource of the utmost value for all scholars studying SARS-CoV infections. It should also be of great interest to clinicians who may be facing an overwhelming number of individuals affected with COVID-19, with over 267 million global cases documented as of the first week of December 2021).

Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. >- NMR spectroscopy for the characterization of photoprotective compounds in cyanobacteria- Coffee assessment using 1H NMR spectroscopy and multivariate data analysis: a review- Evaluation of structure-property relationship of coconut shell lignins by NMR spectroscopy: from biorefinery to high-added value products- Application of NMR spectroscopy in chiral recognition of drugs- NMR-based metabolomics: general aspects and applications in cancer diagnosis

The art of architecture is an important aesthetic element that can leave a lasting impression in one's mind about the values of a society. Today's architectural art, education, and culture have gradually turned into engineering practices and more technical pursuits. Architecture in Fictional Literature is a book written with the aim of understanding the concept of living spaces as portrayed in works of fiction and to open the doors to a new perspective for readers on the art of architecture.It is a collection of essays written by educators and literary critics about how architecture is presented in 28 selected literary works of fiction. These selected works, which include well-known works such as Hugo's Hunchback of Notre Dame, Kafka's The Castle, Swift's Gulliver's Travels, Tolkien's The Lord of the Rings, Carroll's Alice in Wonderland, Fitzgerald's The Great Gatsby, among many others, collectively attempt to illustrate facets of human life in a lucidly expressive way while also having an architectural background added in the narrative. Each essay is unique and brings a diverse range of perspectives on the main theme, while also touching on some niche topics in this area, (such as spatial analysis, urban transformation and time-period settings), all of which have exploratory potential.With this collection, the contributors aspire to initiate the transformation of architectural education by including a blend of literary criticism. By building a foundation of architectural aesthetics, they hope to bridge the gap between the artist and the architect, while also inspiring a new generation of urban planners, landscape artists, and interior designers to consider past works when designing living spaces. Architecture in Fictional Literature is also essential to any enthusiast of fictional works who wants to understand the fictional portrayal of living spaces and architecture in literature.

The Fertility Promise is a complete guide to the often emotional, expensive and confusing process of fertility treatment. The book offers clear explanations and advice to anyone undergoing fertility treatment (such as in vitro fertilization) or anyone seeking information about relevant treatment options. The information includes advice to both male and female patients, LGBT patients, IVF clinics, the IVF treatment process, the issues surrounding IVF 'add-ons', what it is really like to go through fertility treatment and what the future of IVF might look like. Covering every aspect of the topic, the book is an extremely important point of reference for all fertility patients as well as individuals who wish to broaden their perspective on fertility medicine and clinics. The Fertility Promise informs both general readers and empowers fertility patients who are looking for the correct treatment, enabling them to clearly understand the fertility treatment process and to ask appropriate and often revealing questions on the subject.

The kidneys are a vital organ present in humans and vertebrate animals. Various toxic chemicals, present in food and water adversely affect the kidneys. Plants and plant-derived compounds have been a major source for the treatment and cure of diseases since ancient times. Even today, almost 25% of the prescription drugs for renal problems are sourced from plants. An Introduction to Nephroprotective Plants gives an overview of nephrotoxicity and medicinal plants used for protecting the kidney and reducing the effect of kidney toxicity and managing renal diseases. This book is an answer to the current gaps in knowledge resources on nephroprotective plants. The reader is introduced to the basic physiology of the renal excretory system and its disorders. The introduction is followed by chapters which give information on medicinal plants used in traditional systems of medicine (both codified and noncodified). Information about plant parts used, method of use and dosage is provided along with references. Key Features: - Simple structured presentation in six chapters- Includes an introduction to the urinary system and its diseases- Includes information about codified and noncodified medicinal plants used for neuroprotection- Covers phytochemicals extracted from medicinal plants which are screened and used in modern medicine for nephroprotection in detail.- Covers ethnobotanical and polyherbal formulations- References for further reading

This book focuses on cases and studies of interest to mechanical engineers and industrial technicians. The considered applications in this volume are widely used in several industrial fields particularly in the automotive and aviation industries. Readers will understand the theory and techniques which are used in each application covered in each chapter. The book contents include the following topics: Numerical analysis of hydrokinetic turbinesComputational fluid dynamics of a CuO based nanofluid in mini-channel cross-sectionsOrthodontic biomechanics of a NiTi arch wiresReynold's number effects on fluid flow through Savonius rotorsEffect of operating parameters on Zn-Mn alloys deposited from additive-free chloride bathOptical properties and stability of a blue-emitting phosphor (Sr2P2O7: Eu2+) Under UV and VUV excitationNumerical study of the influence of nanofluid type on thermal improvement in a three dimensional mini channelElectrochemical studies and characterization of Zn-Mn coatings deposited in the presence of novel organic additivesPrediction of fire and smoke propagation under a range of external conditions>The presented case studies and development approaches aim to provide the readers, such as graduate students, PhD candidates and professionals with basic and applied information broadly related to mechanical engineering and technology.

How to Design Optimization Algorithms by Applying Natural Behavioral Patterns is a guide book that introduces readers to optimization algorithms based on natural language processing. Readers will learn about the basic concept of optimization, optimization algorithm fundamentals and the methods employed to formulate natural ideas and behaviors into algorithms. Readers will learn how to create their own algorithm from the information provided in the text. The book is a simple reference to students and programming enthusiasts who are interested in learning about optimization and the process of designing algorithms designed to mimic natural phenomena.

This book presents information about the high enzymatic reactivity of reactive oxygen species. Chapters in the book cover several aspects of the topic such as the sources, formation mechanisms, reaction centers, oxidation-reduction reactions, cellular respiration chemistry, enzymatic kinetics, mitochondrial and plastid electron transport chains, oxidation-reduction potential, reaction constants, reaction velocity and reaction mechanisms involved, cellular cytotoxicity, antioxidant defense mechanisms in plants and animals, response of plants to conditions of environmental stress, xenobiotics, and the thermodynamics inherent to oxygen metabolism. The book also features a chapter on flavonoids which highlights a paradoxical facet of the affinity of reactive oxygen species for enzymes. Flavonoids are mainly antioxidant molecules as they act as trappers of reactive oxygen species. The chapter informs readers about the metabolic pathways mediated by enzymes through wich flavonoids become promoters of these same reactive oxygen species. All chapters present the subject in a simple, analytical format, while highlighting the scientific evidence gathered by researchers so far. The volume is an interesting reference for scholars learning about the biochemistry and enzymology of oxygen and its free radical derivatives.

Bentham Briefs in Biomedicine and Pharmacotherapy brings new trends and techniques in pharmacology and medical biochemistry to the forefront through unique volumes. Each volume provides a brief review of selected topics, written by scientific experts. The book series is essential reading for graduate students and researchers in pharmacology and life sciences as well as medical professionals seeking knowledge for research oriented projects. The first volume, Oxidative Stress and Natural Antioxidants, is a compilation of articles about free radicals (which are extremely reactive, short-lived molecules with unpaired electron valency), and antioxidants (which are stabilizing agents of free radicals in the body). The volume presents 17 chapters on the biochemistry of free radicals and antioxidants, with contributions from over 60 scientists. Readers will understand the basic and clinical aspects of free radical biomedicine, the role of antioxidants in neutralizing free radicals through physiological homeostasis, as well as the range of natural compounds which can be used to combat oxidative stress. The chapters also cover special topics such as recent advances in preparation methods of antioxidants, and industrial applications of antioxidants. The range of topics in this volume provide a consolidated reference for a broad set of readers on the subject.

Essentials of Pediatric Surgery is an introductory reference on basic pediatric medicine and surgery. The book provides the reader the information on which a surgeon relies on in diagnosis and treatment. >Key Features: - 8 chapters covering introductory topics about pediatric physiology and surgery- Includes chapters which cover specialized domains in the subject based on different parts of the body- Chapters include information about clinical presentations, diagnosis and treatment of different conditions- Simple, structured layout for easy understanding>Essentials of Pediatric Surgery is a handy textbook for both medical students studying modules on pediatric surgery and residents in training in pediatric clinics.

Biochemistry: Fundamentals and Bioenergetics presents information about the basic and applied aspects of the chemistry of living organisms. The textbook covers the scope and importance of biochemistry, the latest physical techniques to determine biomolecular structure, detailed classification, structure and function of biomolecules such as carbohydrates, lipids, amino acids, proteins, nucleic acids, vitamins, enzymes and hormones. Readers will also learn about processes central to energy metabolism including photosynthesis and respiration, oxidative phosphorylation, DNA replication, transcription and translation, recombinant DNA technology. Key Features- logical approach to biochemistry with several examples- 10 organized chapters on biochemistry fundamentals and metabolism- focus on biomolecules and biochemical processes>Biochemistry: Fundamentals and Bioenergetics is a useful textbook for undergraduate students involved in courses in life sciences, biochemistry and other branches of natural scienc

COVID-19: Epidemiology, Biochemistry, and Diagnostics explains COVID-19 from multidisciplinary angles such as the evolution of SARS-COV, genetic techniques to study the virus, and diagnostic methodologies widely used in the global COVID-19 pandemic. The chapters in this book provide the reader with up-to-date literature about research on SARS-CoV-2 through three parts: I) Evolution and Entry of SARS-CoV-2 into the hostII) Genetic Alteration and Structural Determination of SARS-CoV-2 Proteins>Key Features: - 15 chapters on SAR-CoV-2 in a multidisciplinary context- Provides a comprehensive overview of SARS-CoV-2 evolution and genetics- Provides biochemical information about SARS-CoV-2 proteins and receptor targets (both structural and non-structural proteins)- Includes an overview of several methods of detecting SARS-CoV-2 virus particles (ELISA, PCR, Neutralizing Antibodies- Covers some critical diagnostic modalities for COVID-19 diagnosis>Readers will understand the significance of phylogenetic analysis of coronaviruses, along with the pathogenesis of COVID-19 and related diseases such as SARS and MERS. Applications of biochemical technologies such as RT-PCR and CRISPR are also demonstrated in the text. This book is a comprehensive introduction to COVID-19 research for medical researchers, microbiologists and virologists. Students in academic programs in life sciences and medicine will also benefit from the information provided in the book.

Cardiac Care and COVID-19: Perspectives in Medical Practice is an accessible reference on diagnoses and treatment modalities for cardiac diseases in general, and emergency cardiac conditions to be more specific, with respect to the current COVID-19 pandemic. Chapters in the book give updated descriptions of common problems in emergency medicine and cardiovascular disease. Each chapter is dedicated to a specific cardiovascular disease and explains management principles, diagnostic procedures and therapy. Examples of medical cases have also been used to highlight complex issues to give a concrete understanding of the cardiac care in COVID-19 patients to the medical practitioner, whether they are involved in critical care or in outpatient clinics.Key Features: - Clinical guidelines for critical care and cardiovascular management of COVID-19 patients- Topic-based information about cardiovascular diseases- Covers a range of cardiovascular problems including myocarditis, arrhythmias, chest pain, acute coronary syndrome- Information on pulmonary embolism and associated problems- Reader friendly presentation- Case-based examples for explaining conceptsThe range of topics combined with the simple presentation make this an essential reference for healthcare workers in emergency medicine, cardiology and nursing. General physicians interested in the cardiovascular impact of COVID-19 will also benefit from the information provided in the book.

Introduction to Molecular Genomics introduces the college student to the fundamental concepts of molecular biology and genomics. The text puts an emphasis on important topics in the subject that contribute to the learner's understanding. These topics include molecular genomics, biodiversity and molecular phenomenon behind evolution of species, modern molecular methods for enhanced genomics research, DNA modifications at the molecular level for transgenic animal species, the role of cell environment on the gene expression, to name a few. The have been designed to suit the requirements of taught courses in molecular biology, genomics and biochemistry. Key features- Covers basic concepts on key topics in molecular biology and genomics- Simple easy-to-read layout- Includes references for further reading- Includes a section on ethical aspects of scientific research

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. Contents of this volume include: - Metal-Free and Acid-Free Activation of Carbonyl Moiety Using Molecular Halogens or N-Halamines- Anti-algal Study on Polymeric Coating Containing Metal-Metal Oxide Core-shell Nanoparticles- Functionalized Catalyst for Efficient Nucleophilic and Electrophilic Fluorination- Synthesis and Applications of Small Fluorescent Molecules- Recent Achievements in the Synthesis of Aromatic Five-Membered Heterocycles Containing One Heteroatom- Basic Ionic Liquid Catalyzed Cycloaddition Reactions for the Synthesis of 1, 2, 3-Triazoles

This book is a guide for researchers, academics and experimentalists who wish to explore density functional theory (DFT) on selected molecular systems. The salient features of the book include concise and complete coverage of DFT on biologically active molecules, a basic guide to DFT for beginners followed by its computational application using a powerful Gaussian program. Subsequently, discussions on synthetic compounds, amino acids, and natural products have been offered by the authors for the benefit of the reader. The book also features an exclusive chapter on the quantum theory of atoms in molecules and is supplemented by an appendix on the Gaussian output for methane.Key Features: - basic introduction of density functional theory- practical introduction to Gaussian program- interpretation of input and output files- explanation of calculated parameters- examples of several bioactive molecules (syenthetic and natural)- correlation between theory and experiments- exploration of the hydrogen bonds- appendix covering Gaussian outputs for methane- beginner friendly text- references at the end of each chapterDFT Based Studies on Bioactive Molecules is a suitable handbook for academics, students and researchers who are learning the basic biophysics and computational chemistry of bioactive molecules with reference to DFT models.

Mind Maps in Clinical Chemistry presents information about clinical laboratory techniques for junior healthcare professionals, medical residents and students. Each chapter enables readers to suggest, arrange and interpret clinical chemistry tests effectively with the objective of enhancing clinical care.>Key Featuresi. Topic-based presentation through 31 chapters in 6 sectionsii. Coverage of practical and theoretical knowledgeiii. Lucid and integrated presentation of conceptsiv. Wide range of topics covered including tumor detection, special topics in clinical biochemistry, the clinical chemistry of diseases, lab instrumentation, and reference ranges in medical diagnosis>Mind Maps in Clinical Chemistry is an ideal textbook for quick and easy learning of clinical laboratory knowledge for undergraduate and graduate students as well as teachers instructing courses at these levels.

Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spices have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices and Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are a common part of regional diets and folk medicine.The fourth volume of this series features the following reviews: 1. Pharmacological effects of Curcuma longa, focused on anti-inflammatory, antioxidant and immunomodulatory effects2. Ethnomedicinal uses, Phytochemistry, Pharmacological effects, Pre-clinical and Clinical studies on flaxseed: A spice and culinary herb-based formulations and its constituents3. Nigella sativa (Prophetic medicine): The Miracle Herb4. Properties of Mexican oregano (Lippia spp.) essential oils and their use in aquaculture5. Curry leaf: An insight into its Pharmacological activities, Medicinal profile, and Phytochemistry

This reference informs readers about nanoscale design and synthesis of different nanomaterials. Chapters of the book account for variable nanoarchitecture, while explaining concepts which are central to the field of nanotechnology. It explains how nanodevices and microdevices can be used for nanophotonics, biophotonics and drug delivery applications. Advanced biochemical techniques ranging from fluorescence, plasmonics, enhanced plasmonics (EP) to metal enhanced fluorescence (MEF) from colloidal dispersion to single luminescent nanoplatforms and nanospectroscopy, microfluidics, nanofluidics, silica wave-guiding, lasers, nanolasers and photonic circuits for enhanced signal detections are also presented. In addition, proof of concept ideas of microdevices and nanodevices to real applications within other allied disciplines such as genomics, biochemistry, drug delivery and clinical chemistry (based on advanced optical detection and imaging) are highlighted. The book is an informative reference for readers studying biochemistry, pharmacology, biomedical engineering and related subjects at all levels, as well as general readers who want to learn about advanced applications in optics and photonics.

Contemporary Endoscopic Spine Surgery brings the reader the most up-to-date information on the endoscopy of the spine. Key opinion leaders from around the world have come together to present the clinical evidence behind their competitive endoscopic spinal surgery protocols. Chapters in the series cover a range of aspects of spine surgery including spinal pain generators, preoperative workup with modern independent predictors of favorable clinical outcomes with endoscopy, anesthesia in an outpatient setting, management of complications, and a fresh look at technology advances in a historical context. The reader will have a first-row seat during the illustrative discussions of expanded surgical indications from herniated disc to more complex clinical problems, including stenosis, instability, and deformity in patients with advanced degenerative disease of the human spine. Contemporary Endoscopic Spine Surgery is divided into three volumes: Cervical Spine, Lumbar Spine, and Advanced Technologies to capture an accurate snapshot in time of this fast-moving field. It is intended as a comprehensive go-to reference text for surgeons in graduate residency and postgraduate fellowship training programs and for practicing spine surgeons interested in looking for the scientific foundation for their practice expansion into endoscopic surgery. This volume (Cervical Spine) covers the following topicsCervical Endoscopy: Historical Perspectives, Present & Future Anesthesia For Minimally Invasive Surgery Of The CervicalAlgorithms To Choose Between Anterior And Posterior Cervical EndoscopyContemporary Clinical Decision Making In Full Endoscopic Cervical Spine SurgeryIndications And Outcomes With Endoscopic Posterior Cervical RhizotomyAnterior Endoscopic Cervical DiscectomyAnterior Transcorporeal Approach Of Percutaneous Endoscopic Cervical DiscectomyAnterior Endoscopic Cervical Discectomy And Foraminoplasty For Herniated Disc And Lateral Canal StenosisPosterior Full Endoscopic Cervical Discectomy & ForaminotomyEndoscopic Decompression For Cervical Spondylotic Myelopathy

Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. The seventh volume of the book features reviews on these topics: - Essential oils and monoterpenes as potential anti-cancer agents- Drug delivery systems and emerging immunotherapeutic strategies for the treatment of glioblastoma- CTDNA in solid tumors- Cholesterol treatments (including Pitavastatin) and their potential in cancer treatment

Foods for Special Dietary Regimens is an overview of alimentation for people with specific medical conditions. Each of the nine featured chapters describes a recommended diet with special reference to the lifestyle or disease conditions in a specific patient group. The book covers a diverse range of patient groups that have special nutritional requirements including the elderly, athletes, vegetarians, diabetics and phenylketonurics to name a few. Diets for individuals affected by specific diseases such as celiac disease, autism, dyslipidemia, and COVID-19 are also recommended. Readers will gain a broad perspective about special dietary regimens, including information about what works and what does not for different patient groups, and potential avenues of research in this area. Key Features: - 9 chapters organized into a simple reader-friendly format- guidelines for patient groups on lifestyle- information for patient groups based on different clinically relevant diseases (including COVID-19)- information about general concepts and clinical research- references for further reading

The Abu Serga Church is one of the oldest known Coptic churches in Egypt, with a history of almost 1700 years. This reference work presents a comprehensive geotechnical and geophysical survey of the vicinity of the Abu Serga Church. The book details the information of the survey using classical and modern methods of geotechnical engineering while keeping contemporary issues faced by site investigators in view. Chapters provide the data of the church site while covering topics of interest to students such as seismic analysis, 3-D modeling and historical preservation principles. Advanced methods of interest to engineers such as mathematical analysis using finite element methods are also covered. This work provides key data about the Abu Sega Church site and is of interest to scholars and engineers involved in conservation engineering of architectural heritage (or built heritage), as well as readers interested in church studies.

Frontiers in Clinical Drug Research - Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research - Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology.The seventh volume of this series features these interesting reviews: - Nucleic acid and peptide aptamers as potential antiviral drugs- Host-directed, antibiotic-adjuvant combination, and antibiotic-antibiotic combinations for treating multidrug-resistant (mdr) gram-negative pathogens- Bioactive substances as anti-infective strategies against clostridioides difficile- Anti-toxoplasma drug discovery and natural products: a brief overview- Development of antimalarial and antileishmanial drugs from amazonian biodiversity

The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings.This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives.Key Features: Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students.Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19.Six chapters in the first part which focus on clinical basics of COVID-19.Six chapters in the second part which cover broader topics for practical infection control.Multiple tables and figures which summarize and highlight important points.Presents a summary of the current standards for the evaluation and diagnosis of COVID-19.Features a detailed list of references, abbreviations, and symbols.This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.