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This reference reviews the reported literature on new approaches of nanocomposite material preparation and their applications in the development of physical, chemical, electrochemical, biological, fluorescence and colorimetric sensors. Sensor nanomaterials have been extensively used to amplify signals in the detection of a range of chemicals including toxic gases, biochemical nutrients, ions, explosives, pesticides and drugs to name a few. 14 chapter contributions highlight state-of-the-art sensors in recent years by outlining the synthesis, role and progress of nanocomposite materials in fabricating flexible and multifunctional sensing platforms in sensor technologies. Chapters first introduce the reader to nanocomposite materials and their role in making a wide array of sensors including metal-organic, graphene-based and polymeric sensors. The chapters then progress into applications of sensors for the detection of chemicals such as blood glucose, heavy metal and other toxic ions, hydrazine, humidity and explosive. Each chapter explains the required materials for electrodes and material components for a specific sensor platform with additional information about sample collection, threshold values and perspectives where appropriate. The book is intended as a compilation of knowledge for designing novel nanocomposite materials to be used as sensing platforms in sensor technologies. It serves as an informative resource for a broad range of readers including graduates and post-graduates, Ph. D. scholars, faculty members and professionals working in the area of material science, the healthcare industry, biological sciences, medical sciences, and environmental sciences.

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. Volume 10 of the series continues to present novel information about new and interesting approaches to treat common neurological disorders, with a focus on neurodegeneration and pain medicine. The volume presents 7 detailed reviews in total. - Neurodegenerative disease: prevention and treatment through plant extracts therapy- Emerging novel approaches and recent advances in Parkinson's disease treatment and diagnosis- Neurotrophic factors to combat neurodegeneration- Neural bases of executive function in ADHD children as assessed using FNIRS- Modulation of mesenchymal stem cells, glial cells and the immune system by oligodeoxynucleotides as a novel multi-target therapeutic approach against chronic pain- Chronic pain: focus on anticonvulsants- A review of the impact of testosterone on brain and aging-related decline in brain behavioural function

Educational technology refers to the preparation and use of electronic resources, computer applications, and audio-visual aids which are used in the teaching and learning process. For administrators, the term also includes the planning, organization validation, evaluation, and implementation of all kinds of educational programs. Educational technology is now important for the selection of appropriate teaching media as well as the development, and application of curricula.Fundamentals of Educational Technology work explains the basic facts about educational technology to inform teachers and students. The book includes 6 chapters which cover the subject in a simple manner suitable for learners in education programs. Key Features: - 6 organized chapters on the basics of educational technology and media- Simple reader-friendly organization of contents with relevant diagrams- Gives a historical perspective of the field- Gives an overview of digital and electronic tools for educators- Includes information about relevant teaching methods- Gives an overview of the role of electronic and digital media in education>Fundamentals of Educational Technology serves as a basic guide for educational instructors and administrators on educational technology and its role in teaching and designing educational programs at all levels.

Common Pediatric Diseases: An Updated Review informs the reader about common diseases in children that are encountered by pediatricians and family physicians. Each of the 14 chapters in the volume presents updated information for readers with the aim to give them a current perspective on the topic. This book is a handy and practical compendium for medical students and healthcare professionals involved in general practice and pediatric clinics.The text starts with a quick introduction to pediatric diseases, before progressing towards specific diseases in children. The list of topics in this book includes pediatric rheumatological diseases, common oral diseases, pediatric metabolic syndromes, pediatric epilepsy syndromes, pediatric demyelinating disorder, genetic epileptic encephalopathies (with an algorithmic diagnostic approach), Henoch-Schonlein purpura, atopic dermatitis, childhood-onset systemic lupus erythematosus, Severe Combined Immunodeficiency, PFAPA, aphthous stomatitis, pharyngitis, cervical adenitis syndrome and pediatric hepatoblastoma.

21st Century Challenges in Antimicrobial Therapy and Stewardship addresses selected topics that are of importance in the practice of infectious disease management. The text starts by illustrating the global landscape of antimicrobial drug resistance, which influences antimicrobial use and therapeutic decisions in the clinic. The contributors explain the reasons for the spread of antibiotic resistance, the pharmacology of antibiotics of different classes, innovative drug delivery methods which can improve the efficacy and safety of new drug candidates and achieve targeted drug delivery as well as drug resistance monitoring techniques and issues in the practice of antimicrobial stewardship and infection control.Key Features: - 14 organized chapters on several aspects of antimicrobial therapy and stewardship- Introductory knowledge on global antimicrobial trends- Coverage of molecular basis of antimicrobial resistance in gram positive, gram negative and fungal microbes- Focused coverage on new developments in antimicrobial drug development, drug delivery, formulation and diagnostic tools- Information on unmet needs of patients and clinicians, including the treatment of difficult infections- Comprehensive coverage of issues in antimicrobial stewardship21st Century Challenges in Antimicrobial Therapy and Stewardship brings to readers - healthcare administrators, educators, pharmacists, clinicians and students, alike - the knowledge of the molecular basis of antimicrobial drug therapy, drug resistance in pathogens and current practices in antimicrobial stewardship programs. This knowledge, in turn, fosters an awareness among healthcare industry participants to collaborate in an interprofessional environment to combat multidrug resistance

Long-standing artworks and monuments show the wisdom and cultural identity of an ancient society along with the educational, material and spiritual merits of the people of that time. However, many historical artifacts and cultural monuments have been eroded over time and are in danger of deterioration beyond repair. There is a need to protect and conserve these artifacts. Restoration and preservation requires a multidisciplinary understanding of the inherent properties of these works based on the type of material and sufficient information in the properties of protective and conservation materials and research methods. Protective Material Coatings For Preserving Cultural Heritage Monuments and Artwork aims to familiarize students with the recent practices in conservation and restoration science in recent years by presenting a modern orientation on the subject focused on material coatings. Readers will be able to understand the properties of different materials in antique objects and how to adopt appropriate treatment methods based on these properties.>Protective Material Coatings For Preserving Cultural Heritage Monuments and Artwork is an ideal book for students of archeology, architecture, materials science and contemporary arts courses who are required to learn about the techniques of preserving antique buildings and works of art. It also serves as a handy reference for professionals and general readers interested in the curation of museums and the conservation of buildings, and cultural heritage sites.

This reference summarizes information about pharmaceuticals that can target infectious strains of coronaviruses to neutralize infections. Chapters focus on SARS-CoV-2, drug discovery methods and natural methods to combat the virus, which is a causative agent of COVID-19. Specifically, the book presents 5 chapters written by expert scholar on the following topics: Structure-Based Drug Discovery Approaches Applied to SARS-CoV-2 (the causative agent COVID- 19)Potential Antiviral Medicinal Plants against Novel SARS-CoV-2Infections Caused by SARS Coronaviruses: Main Characteristics, Targets and InhibitorsNatural Sourced Traditional Indian and Chinese Medicines to Combat COVID- 19Peptidomimetic and Peptide-Derived Agents Against 3CLpro from Coronaviruses The book contents present both conventional drug design and traditional approaches to discovering relevant drugs in an easy-to-read approach, which is supplemented by bibliographic references. It is intended as a reference for students (pharmacology, pharmacy) and researchers (virology) who are seeking information about antiviral drugs that can be used against coronaviruses.

The field of sleep medicine has gone through tremendous evolution since the discovery of REM sleep in 1953 and remarkable research in recent years has led to multiple advances in sleep medicine. Approvals for new medicines for treating sleep disorders along with new evidence-based interventions for insomnia and sleep apnea, have transformed sleep medicine into a medical specialty in its own right. The Latest Trends in Sleep Medicine reviews the most important improvements in sleep medicine, with contributions from over fifteen international and respected experts in the discipline. Ten chapters cover topics of interest to healthcare professionals who are focused on somnology such as the management of sleep disorders, restless leg syndrome, sleep apnea medication and surgery, REM sleep behavior disorder and cognitive behavioral therapy for insomnia. In addition to these topics in medicine, the contributors present broader picture of sleep medicine by reviewing secondary topics such as sleep and aging, and driving safety. The Latest Trends in Sleep Medicine will be useful to healthcare professionals seeking to improve their understanding about contemporary sleep medicine. It also serves as a timely update for respiratory and sleep medicine clinicians, whose efforts are still needed in treating and improving the quality and length of life in patients with complex sleep disorders.

Since ancient times, yeasts have been used for brewing and breadmaking processes. They now represent a flagship organism for alcoholic fermentation processes. The ubiquity of some yeast species also offers microbiologists a heterologous gene-expression platform, making them a model organism for studying eukaryotes. Yeasts: from Nature to Bioprocesses brings together information about the origin and evolution of yeasts, their ecological relationships, and the main taxonomic groups into a single volume. The book initially explores six significant yeast genera in detailed chapters. The book then delves into the main biotechnological processes in which both prospected and engineered yeasts are successfully employed. Yeasts: from Nature to Bioprocesses, therefore, elucidates the leading role of these single-cell organisms for industrial microbiology in environmental, health, social, and economic terms. This book is a comprehensive, multidisciplinary resource for general readers as well as scholars of all levels who want to know all about yeast microbiology and their industrial applications.

Frontiers in Clinical Drug Research - Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research - Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The fifth volume of this series features 7 reviews with a focus on thalassemia treatment and preeclampsia among other topics. - Recent advances in the diagnosis and management of pulmonary embolism- An evidence-based approach to treatment with iron chelators in transfusion- dependent thalassemia patients: present trends and future scenario- Current and future treatments of iron overload in thalassemia patients- Preeclampsia: biological and clinical aspects- Haematological modulations by fixed dose combination (FDC) of tramadol hydrochloride/paracetamol (THP)- Possible use of eculizumab in critically ill patients infected with covid-19 role of complement c5, neutrophils, and nets in the induction DIC, sepsis, and MOF hematological markers- Emerging diagnostic and therapeutic targets in preeclampsia

Many beginners find physics to be a challenging subject to learn, and the difficulty extends to each branch of physics. It would be preferable for beginners to learn about different branches of physics as quickly as possible with a simplified understanding of the relevant mathematical relationships. After learning the position of each field in physics, it becomes easier to learn details of each field. In this book, special functions are not used to explain the solutions of equations.Fundamentals of Analysis In Physics summarizes the analytical methods in different fields of physics The book covers several known fields of physics and is a useful text for beginners in physics, college and university students, and working professionals who may not have a background in mathematics or physics. Key features: - Summarizes information about different fields in physics in 150 pages- Covers 7 different fields of physics (classical mechanics, electromagnetism, quantum mechanics, relativistic quantum mechanics, statistical mechanics and more) in 7 separate chapters-Contains simple explanations without the use of special functions

Chemistry of Bipyrazoles: Synthesis and Applications covers the synthetic pathways for all types of bipyrazoles. 5 chapters cover bipyrazole systems, N, N- and N, C-bipyrazoles, namely 1,1`-bipyrazole, 1,3`-bipyrazole, 1,4`-bipyrazole, 3,3`-bipyrazoles, 3,4`-bipyrazoles and 4,4`-bipyrazoles The contents explain several types of reactions: 1) condensation reactions of hydrazines with tetracarbonyls, dihydroxydicarbonyl compounds or pyrazole-based difunctional compounds; 2) 1,3-dipolar cycloaddition of pyrazole-based hydrazonoyl halides with activated methylene compounds; 3) metal catalyzed cross-coupling reactions.>The book contents are presented in an easy-to-understand manner suitable for readers in organic chemistry at senior levels of education and industry expertise. Each chapter is supplemented with detailed references.

Advanced Techniques of Analytical Chemistry explains analytical chemistry in an accessible manner for students. The book provides basic and practical knowledge that helps the learner to understand the methods used in conducting experiments. Readers will understand the key concepts of qualitative and quantitative analysis through easy-to-read chapters written for chemistry students. Volume 1 covers the topic of volumetric analysis in detail. Topic-wise chapters introduce the reader to volumetric titrations and then explain the range of titration techniques which include aqueous acid-base titration, non-aqueous titration, redox titration, complexometric titration and some miscellaneous methods like diazotisation titration, Kjeldahl's method and the oxygen flask combustion method. The combination of basic and advanced methods makes this an ideal textbook for chemistry students at graduate and undergraduate levels as well as an ideal handbook for the laboratory instructor.

Voltammetry for Sensing Applications familiarizes readers with recent advancements in the field of electrochemical analysis. The book features 16 chapters which cover many applications of voltammetric analysis such as drug testing and analysis, sensors for point-of-care devices, sensors for diverse analysis, advanced energy storage devices, clinical sample analysis, sensors for the detection of heavy metals, nanomaterials, disease detection, immune sensors, food sample analysis, and anti-inflammatory and anticancer drug detection. Many of the current methods of voltammetry offer increased stability, repeatability, high performance, cost-effectiveness, time-saving, sensitivity, and the chapters also cover appropriate applications for the sensing tools and methodologies which are imperative in electrochemical, environment, biological, medicinal, and food safety analysis. This informative reference serves as a timely and comprehensive update on voltammetry and sensing materials for chemistry scholars and industrial chemists alike.

Lean Management Solutions for Contemporary Manufacturing Operations: Applications in the automotive industry covers recent techniques aimed at improving manufacturing activities in automotive factories in the time of the fourth industrial revolution. The book informs the reader about some improvements in hard skills (such as technical concepts, new tools, processes, and applied designs), as well as soft skills (strategic planning and the psychology of motivating human resources in manufacturing setups). The book also presents insight for managers who are working with a niche of employees with disabilities with respect to the automotive industry. Topics in the book include: Application of Graph Theory in Workplace DesignApplied DesignDisability and the 4th Industrial RevolutionPeople Development, Motivation & ResultsLow Cost Logistics SolutionsAgile Methodologies in Manufacturing ProjectsThis book is a concise, informative reference which updates the reader on recent strategies to maximize productivity in the auto manufacturing sector.

This volume presents a clear understanding of the quantum mechanics of particles with reference to the current understanding of theory of relativity, gravitation, and electromagnetism, including essential phenomena as spin, the graviton spin, black holes, and the quantum particle states in the extreme conditions of a black hole formation, and of the Schwarzschild boundary. The reader is introduced to the recent theory of the quantum particle dynamics as a distribution of matter propagating with the velocity of the waves. The text describes this distribution by a Fourier space-time series expansion, which we call the wave function. The subsequent chapters delve into the mechanics of quantum particles in a gravitational field, charged particles in a gravitational field and finally, the least action and matter-field dynamics in a gravitational field. The book also explains important rules in quantum mechanics such as the mass quantization rule, Dirac's formulation of the general theory of relativity, electromagnetic field theory, quantum particle interactions and more. The volume serves as a concise introduction to the complex topic of quantum particle mechanics for scholars involved in advanced physics courses.

This reference presents a collection of studies which highlight new developments in improving manufacturing processes and performance. The book includes 11 chapters which cover unique topics of interest to production engineers. These topics include the production of advanced composite materials and alloys to the use of sensors to evaluate production processes, product testing and evaluation (in production and storage environments), and the development and testing of an unmanned aerial vehicle.Chapters have been contributed by several scholars, who give a unique perspective on specific aspects of manufacturing and industrial production. The book also covers recent technologies such as additive manufacturing. Each chapter presents the study in an experimental manner highlighting the theory, methods, and results, where applicable. References for further reading are also provided.This book is intended to provide researchers and engineers with new data and cases for industrial manufacturing processes which may be applied in different industrial sectors.

Medicinal and Environmental Chemistry: Experimental Advances and Simulations is a collection of topics that highlight the use of pharmaceutical chemistry to assess the environment or make drug design and chemical testing more environment friendly. The ten chapters included in the first part of this book set cover diverse topics, blending the fields of environmental chemistry and medicinal chemistry and have been authored by experts, scientists and academicians from renowned institutions. The book introduces the reader to environmental contaminants and techniques for their quantification and removal. A medicinal perspective for effects and remediation of environmental hazards, and therapeutic strategies available to design new and safer drugs, is addressed with a focus on knowledge about experimental and simulation methods. To further elaborate the importance of environmentally safe chemical practice, the concept of green chemistry has also been covered. Specialized chapters have been included in the book about persistent organic pollutants, heavy metal and plastic pollutants, the effect of environmental xenoesterogens on human health and the potential of natural products to combat ecotoxicity.Key Features: 1.10 topics which blend environmental chemistry and medicinal chemistry2. Contributions from more than 30 experts3. Includes introductory topics on environmental pollutants, investigative techniques in drug design and environmental risk assessment and green chemistry4. Includes specialized topics on persistent pollutants, ecotoxicity remediation and xenoestrogens5. Bibliographic referencesThis reference is an essential source of information for readers and scholars involved in environmental chemistry, pollution management and pharmaceutical chemistry courses at graduate and undergraduate levels. Professionals and students involved in occupational medicine will also benefit from the wide range of topics covered.

Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. The eighth volume of the book features reviews on these topics: - Key data management elements in clinical trials for oncological therapeutics- Prospects for therapeutic targeting of microRNAs in brain tumors- Breast cancer vaccines: current status and future approach- Desmocollin-3 and cancer- MDM2-p53 antagonists under clinical evaluation: a promising cancer targeted therapy for cancer patients harbouring wild-type tp53- Towards targeted therapy: anticancer agents targeting cell organelle mitochondria- Anticancer therapeutic strategies in gliomas: chemotherapy, immunotherapy, and molecularly targeted therapy in adults