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Biotechnology and Drug Development for Targeting Human Diseases is an insightful compendium on drug development technologies for professionals and students in biotechnology and pharmacology. This book meticulously explores the intersection of biotechnology with drug development, emphasizing its crucial role in creating new therapies for human disease. Central to the book is the innovative use of biotechnology in understanding and treating diseases. It begins with an exploration of multi-omics profiles, shedding light on disease mechanisms and drug development. Subsequent chapters explain in silico methods for drug design, the role of natural products in antimicrobial applications and wound healing, and the use of viruses as carriers in biotechnology. Key features of this reference include a blend of theoretical knowledge and practical insights, detailed analyses of molecular docking in drug discovery, the repurposing of drugs for various diseases, and the emerging field of omics technologies in drug interaction studies. Each chapter is comprehensive, offering current information backed by extensive references, making the book both a foundational and advanced resource.

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in neurology and allied disciplines. The twelfth volume of this series features these reviews: Chapter 1: Recent Drugs Tested in Clinical Trials for Alzheimer's and Parkinson's Diseases Treatment: Current Approaches in Tracking New Drugs Chapter 2: Neurobiology of Placebo: Interpreting Its Evolutionary Origin, Meaning, Mechanisms, Monitoring, and Implications in Therapeutics Chapter 3: Role of Gut Microbiota in Neuroinflammation and Neurological Disorders Chapter 4: The Role of Age in Pediatric Tumors of the Central Nervous System Chapter 5: Drug Repurposing in CNS and Clinical Trials: Recent Achievements and Perspectives Focusing on Epilepsy and Related Comorbidities Chapter 6: Progress on the Development of Oxime Derivatives as a Potential Antidote for Organophosphorus Poisoning.

This volume explores a diverse range of applications for automated machine learning and predictive analytics. The content provides use cases for machine learning in different industries such as healthcare, agriculture, cybersecurity, computing and transportation. Chapter 1 introduces an innovative device for automatically notifying and analyzing the impact of automobile accidents. Chapter 2 focuses on the detection of malaria using systematized image processing techniques. In Chapter 3, an intelligent technique based on LMEPOP and fuzzy logic for the segmentation of defocus blur is discussed. Predictive analytics is introduced in Chapter 4, providing an overview of this emerging field. Chapter 5 delves into discrete event system simulation, offering insights into its applications. The performance analysis of different hypervisors in OS virtualization is explored in Chapter 6. Load balancing in cloud computing is the subject of investigation in Chapter 7. Chapter 8 presents a survey on a facial and fingerprint-based voting system utilizing deep learning techniques. Chapter 9 explores IoT-based automated decision-making with data analytics in agriculture. Biometric recognition through modality fusion is investigated in Chapter 10. Chapter 11 offers a new perspective on evaluating machine learning algorithms for predicting employee performance. Pre-process methods for cardiovascular diseases diagnosis using CT angiography images are discussed in Chapter 12. Chapter 13 presents the implementation of a smart wheelchair using ultrasonic sensors and LabVIEW. Cryptography using the Internet of Things is the focus of Chapter 14. Chapter 15 explores machine learning applications for traffic sign recognition, and the book concludes with Chapter 16, which analyzes machine learning algorithms in healthcare. The book is a resource for academics, researchers, educators and professionals in the technology sector who want to learn about current trends in intelligent technologies.

Biosurfactants, derived from microbes and plants, exhibit diverse properties that help in emulsifying and foaming processes. With applications in pharmaceuticals, cosmetics, and agriculture, they also show antimicrobial and environmental benefits, such as oil removal in polluted areas. Biosurfactants show promise for pollution control and improving agriculture. This reference covers the basic science and major applications of biosurfactants. The book brings together contributions from experts in microbiology, cancer biology, pharmaceutical science, nanotechnology, plant biotechnology and environmental sciences into a single volume. The key features of the book are - Explains the basics of biosurfactants - Discusses novel applications of biosurfactants in the field of medicine, agriculture and environmental sustainability. - Includes special chapters that review the role of biosurfactants in environmental remediation and omics research - Includes detailed references in each chapter This book is an essential resource for learners and professional trainees who require knowledge about biosurfactants. It also provides information for anyone who is working on environmental sustainability projects.

This reference book explains the fundamentals of Bose Einstein Condensation (BEC) in excitons and polaritons. It presents five chapters exploring fundamental concepts and recent developments on the subject. Starting with a historical overview of BEC, the book progresses into the origins and behaviors of excitons and polaritons. Chapters also cover the unique thermalization and relaxation kinetics of excitons, and the distinctive features of polaritons, such as lasing, superfluidity, and quantized vortices. The chapters dedicated to BEC in excitons and polaritons detail experimental techniques, theoretical modeling, recent advancements, and practical applications in a simplified way for beginners. This book serves as a resource for researchers, physicists, and students interested in the phenomena of BEC, providing insights into both the theoretical foundations and the practical implications of excitons and polaritons.

This volume explores IoT architectures, their configuration, and operability in wireless sensor networks. The topics are spread across nine structured chapters covering fundamental and applied knowledge about wireless sensor networks using IoT devices. The book starts with an introduction to the subject, giving readers a quick overview of IoT enabled networks and bio-inspired approaches towards network design. This is followed by chapters explaining optimized routing protocols for accident detection, efficiency and performance analysis. The book concludes with four chapters dedicated to security applications of wireless networks, for homes, urban areas and businesses. Overall, the volume gives a balance of theoretical and practical information for readers. The book is intended as a resource for graduate and postgraduate students for understanding network design for home and embedded applications, specifically using single board computing devices. It also serves as a guide for networking courses and assessments.

Marine Biopharmaceuticals: Scope and Prospects is a collaboration of experts in pharmacology, biology and biochemistry with a focus on Marine Bioprospecting. The book provides an in-depth exploration of promising pharmaceutical compounds found in various marine biota and their therapeutic applications. The comprehensive contents cover marine ecosystems, marine biopharmaceutical, and delve into the chemistry and therapeutic applications of compounds from diverse marine organisms such as seaweeds, sponges, cnidarians, bryozoans, worms, shellfish, tunicates, and fishes. The chapters also highlight approved and marketed marine biota-derived drugs and marine biota-derived drug candidates currently under clinical trials. Marine biopharmaceutical compounds targeting SARS-CoV-2 are also covered, reflecting the latest developments in the field. The editors conclude the book by advocating for the establishment of professional grade Marine Biopharmacy courses at university level to contribute to this emerging field. This reference serves as a guide for researchers and instructors in disciplines such as Pharmaceutical Sciences, Marine Biology, Marine Microbiology, Marine Biochemistry, and Marine Biotechnology. Moreover, it is positioned as a standard reference for libraries in colleges and universities, offering critical insights for drug companies engaged in the development of new drugs from marine biopharmaceuticals.

New technologies like blockchain and Internet of Things (IoT) are constantly improving the state-of-the-art in healthcare services. The trend of keeping medical records in digital formats is also increasing the reliance of modern healthcare service providers on these new technologies. This edited book brings a collection of reviews on blockchain and IoT technologies that are driving innovation in digital and smart healthcare systems. The editors bring an academic and practical approach to assist professionals and readers in understanding computerized healthcare solutions. 16 referenced chapters provide knowledge about fundamental framework, research insights, and empirical evidence for effective smart healthcare applications. The chapters also cover benefits and challenges of specific smart health frameworks, giving an informative overview of the subject. Key themes of the book include: 1. Technological Foundations for Smart Healthcare 2. Blockchain Applications in Healthcare 3. Internet of Things (IoT) in Healthcare 4. Artificial Intelligence (AI) Integration 5. Security, Privacy, and Authentication 6. Medical Imaging and Deep Learning 7. Telemedicine The content in the book is designed to help administrators and healthcare professionals to understand the basics of blockchain tech and IoT in smart healthcare systems and strengthen the competitive advantage of their clinics.

Data Science for Agricultural Innovation and Productivity explores the transformation of agriculture through data-driven practices. This comprehensive book delves into the intersection of data science and farming, offering insights into the potential of big data analytics, machine learning, and IoT integration. Readers will find a wide range of topics covered in 10 chapters, including smart farming, AI applications, hydroponics, and robotics. Expert contributors, including researchers, practitioners, and academics in the fields of data science and agriculture, share their knowledge to provide readers with up-to-date insights and practical applications. The interdisciplinary emphasis of the book gives a well-rounded view of the subject. With real-world examples and case studies, this book demonstrates how data science is being successfully applied in agriculture, inspiring readers to explore new possibilities and contribute to the ongoing transformation of the agricultural sector. Sustainability and future outlook are the key themes, as the book explores how data science can promote environmentally conscious agricultural practices while addressing global food security concerns. Key Features:

This reference is a comprehensive review of genome editing in bacteria. The multi-part book meticulously consolidates research findings and insights on the applications of bacteria across several industries, including food processing and pharmaceutical development. The book covers four overarching themes for readers: a historical perspective of genome editing, genome editing in probiotics, applications of genome editing in agricultural microbiology and genetic engineering in environmental microbiology. The editors have also compiled chapters that provide an in-depth analysis of gene regulation and metabolic engineering through genome editing tools for specific bacteria. Key topics in part 1: - An Overview of advances in CRISPR-CAS research - Applications of CRISPR/CAS9-based genome editing for industrial microorganisms - Gut microbiome modulation to address gut dysbiosis - Bifidobacterium genome editing for probiotic development and metabolic engineering. - Insights into the use of lactic acid bacteria as starter cultures in the food - Genome editing of vegetable-derived L. Plantarum - Genome editing in Bacillus Licheniformis Genome Editing in Bacteria is a definitive reference for scholars, researchers and industry professionals navigating the forefront of bacterial genomics.

Pollution of the aquatic environment is a real threat across the globe. It is becoming a topic of intense study for researchers. It has been updated and almost completely revised. The Mediterranean Sea has been recognized as a target hotspot of the world as the pollutant concentration in this region is greater than the levels in other oceans. The book summarizes research on marine pollutants in the Mediterranean Sea. It presents 5 concise reviews focusing on microplastics, rare earth elements and biotoxins - which are now commonly found in the region. The Editors also emphasize on pollution problems in the Mediterranean region, with 2 chapters presenting studies on Lebanon and Morocco, respectively. The book adds to the collective information on Mediterranean marine pollution. Additionally, references are included at the end of each chapter for the benefit of advanced readers. The contributions also include discussions on important techniques used to monitor and control marine pollution, such as the bio-monitoring of effluents, and ecological impact assessment of microplastic pollution on fish and the environment.

The book content represents comprehensive exploration of the transformative potential and challenges of IoE-based smart cities, fueled by Artificial Intelligence (AI) and Machine Learning (ML) innovations. Key Topics: -Physical layer design considerations that underpin smart city infrastructure-Enabling technologies for intelligent systems within the context of smart computing environments-Smart sensors and actuators, their applications, challenges, and future trends in IoE-based smart cities-Applications, enabling technologies, challenges, and future trends of IoE for smart cities.-The integration of Artificial Intelligence, Natural Language Processing, and smart cities for enhanced urban experiences-Machine learning-based intrusion detection techniques for countering attacks on the Internet of Vehicles-Smartphone-based indoor positioning applications using trilateration and the role of sensors in IoT ecosystems-IoT, blockchain, and cloud-based technology for secure frameworks and data analytics-Blockchain and smart contracts in shaping the future of smart cities. This is a timely reference for researchers, professionals, and students interested in the convergence of IoT, intelligent systems and urban studies into smart city planning and design.

Environmental issues such as overexploitation, pollution and degradation of natural resources have prompted us to look for ways to devise sustainable practices across industrial and public service sectors. Researchers and scientists all over the world are involved in developing strategies and techniques that help us achieve a sustainable environment. Technology for a Sustainable Environment presents an overview of various methods and techniques that can be adapted to sustain the environment. Chapters focus on techniques such as bioremediation, nanotechnology and biotechnology that can play a very important role in achieving environmental sustainability goals. The chapters also provide a detailed account about use of biotechnology, nanotechnology and other techniques in achieving environmental sustainability. Additionally, the book includes a discussion about emerging technologies that promote environmental sustainability like green technologies, biodegradable polymers and plastics. Readers will be able to understand how modern technologies can help in monitoring environmental pollutants, remediation of environmental pollution and prevention of environmental degradation. The book is suitable for readers, professionals and scholars at all levels who require an understanding of the technology in environmental science, environmental engineering and environmental biotechnology.

This book presents numerical computational fluid dynamics (CFD) solutions for studying the effect of fluid-structure interaction (FSI) on evaluation of pressure waves in pipelines with cavitation. The authors develop a uniform one-dimensional model using coupled models. These models consider unsteady friction (UF), Poisson coupling, axial vibration (junction coupling), gas release and viscoelasticity. The authors consider two cases: elastic pipelines and viscoelastic (VE) pipelines. The book starts with a detailed literature review on the relevant methods for calculating transient fluid flow, followed by chapters that explain the mathematical development for calculations and the numerical steps for water hammer and transient cavitation. The concluding chapters present the results for the two pipeline cases. The book is presented in simple language intended for engineering students who want to understand CFD simulations for transient flow in pipelines. Equations are explained in simple steps for easy understanding, and concepts are illustrated with detailed diagrams. The information and the codes demonstrated in the book will equip readers with the knowledge to study hydraulic problems where transients are caused by pump starting, stopping and failure.

Principles of Automation and Control is a concise textbook that explains the basics of robust automation and control strategies. It demonstrates the essentials for meeting consumer needs and ensuring cost-effective manufacturing processes without compromising product quality. With a focus on Industry 4.0, this book explores the principles and applications of automation in industrial systems, emphasizing efficiency, profitability, and flexibility. The thirteen chapters cover automated processes, control theory, computer control devices, industrial automation tools, and practical examples of system automation. The text uses a multidisciplinary approach with simple language to cater to the needs of readers at all levels (learners, beginner engineers, and professionals) seeking to expand their knowledge in automation and control theory and practice. Real-world case studies and empirical findings are also highlighted, which show how automated business solutions can enhance performance.

Data Science and Interdisciplinary Research: Recent Trends and Applications is a compelling edited volume that offers a comprehensive exploration of the latest advancements in data science and interdisciplinary research. Through a collection of 10 insightful chapters, this book showcases diverse models of machine learning, communications, signal processing, and data analysis, illustrating their relevance in various fields. Key Themes: -Advanced Rainfall Prediction: Presents a machine learning model designed to tackle the challenging task of predicting rainfall across multiple countries, showcasing its potential to enhance weather forecasting.-Efficient Cloud Data Clustering: Explains a novel computational approach for clustering large-scale cloud data, addressing the scalability of cloud computing and data analysis.-Secure In-Vehicle Communication: Explores the critical topic of secure communication in in-vehicle networks, emphasizing message authentication and data integrity.-Smart Irrigation 4.0: Details a decision model designed for smart irrigation, integrating agricultural sensor data reliability analysis to optimize water usage in precision agriculture.-Smart Electricity Monitoring: Highlights machine learning-based smart electricity monitoring and fault detection systems, contributing to the development of smart cities.-Enhanced Learning Environments: Investigates the effectiveness of mobile learning in higher education, shedding light on the role of technology in shaping modern learning environments.-Coastal Socio-Economy Study: Presents a case study on the socio-economic conditions of coastal fishing communities, offering insights into the livelihoods and challenges they face.-Signal Noise Removal: Shows filtering techniques for removing noise from ECG signals, enhancing the accuracy of medical data analysis and diagnosis.-Deep Learning in Biomedical Research: Explores deep learning techniques for biomedical research, particularly in the realm of gene identification using Next Generation Sequencing (NGS) data.-Medical Diagnosis through Machine Learning: Concludes with a chapter on breast cancer detection using machine learning concepts, demonstrating the potential of AI-driven diagnostics.

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. Volume 18 presents 7 reviews focused on ionic materials, nanoparticles and nitrogen containing heterocycles in organic synthesis. - Recent synthetic and biological advances in anti-cancer ferrocene-analogues and hybrids - Synthesis of fused nitrogenated heterocycles: intramolecular povarov reaction - Use of barbituric acid as a precursor for the synthesis of bioactive compound - Ionic liquids as solvents and/or catalysts for organic synthesis - Zinc oxide nanomaterials for biomedical applications - Superhydrophobic polymeric nanocomposites coatings for effective corrosion protection - Morphologies and properties of virgin and waste PP nanocomposites

A Primer on Earth Pollution: Pollution Types and Disposal, is an encyclopedia of important research articles and short essays on pollution. Chapters in the initial half provide information about a wide variety of pollutants (dyes and microplastics) and contributing factors (thermal pollution and the impact of GM plants, for instance). Each chapter explains the nature of polluting agents and presents notes and references on preventive measures. Notes on the associated clinical complications due to exposure are also proved where applicable, such as the case of MDR bacteria in marine environments. The latter chapters of the book cover the biotechnology of medical waste disposal using microbes as well as nanotechnology used for limiting the spread of COVID-19.The volume is a handy reference for students and trainees in the field of environmental science as it brings a balance of basic and applied information on the subject of pollution.