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The book presents many of the recent technological and research accomplishments in the area of nanomedicine and nanotechnology. It includes presentations of state of art in the field along with novel approaches in nanomedicine and nanotechnology, and new challenges and opportunities.

This volume addresses efforts to overcome the shortcomings of conventional dosage forms by exploiting the principles of nanoscience to deliver drugs for medical treatment. Nanodispersions are an important aspect because they possess globules/particles in sizes usually below 1000 nm in which the drug is dispersed in a continuous medium employing surface-active agents as stabilizers. With chapters written by experienced scientists and researchers in the field, this volume provides an abundance of information on various aspects of nanodispersions for drug delivery. The book is divided into several sections: nanoemulsions, nanosuspensions, and diverse dispersed systems. The chapters detail what nanodispersions have demonstrated in the past and what they are expoected to continue to do in the future as the technology further evolves.Key features: - Provides an overview of nanoemulsions for drug delivery- Introduces the general principles, classification, and methods of preparation of nanoemulsion-based drug delivery systems- Presents information relevant to specific routes of applications of nanoemulsions- Looks at the various aspects of nanosuspensions, including their formulation components, preparation methods, unique features, methods of characterization, and applications in various routes of administration- Explores nanomicellar approaches for drug delivery- Discusses the preparation, applications, and clinical considerations of nanogels for drug delivery

One of the major areas of emphasis in the field of in chemical science and engineering technology in recent years has been interdisciplinary research, a trend that promises new insights and innovations rooted in cross-disciplinary collaboration. This volume is designed for stepping beyond traditional disciplinary boundaries and applying knowledge and insights from multiple fields. This book, Chemical Science and Engineering Technology: Perspectives on Interdisciplinary Research, provides a selection of chapters on interdisciplinary research in chemical science and engineering technology, taking a conceptual, and practical approach. The book includes case studies and supporting technologies and also explains the conceptual thinking behind current uses and potential uses not yet implemented. International experts with countless years of experience lend this volume credibility.

This important new book provides innovative material, including peer-reviewed chapters and survey articles on new applied research and development, in the scientifically important field of QSAR in medicinal chemistry. QSAR is a growing field because available computing power is continuously increasing, QSAR's potential is enormous, limited only by the quantity and quality of the available experimental input, which are also continuously improving. The number of possible structures for the design of new organic compounds is difficult to imagine, and QSAR helps to predict their activities even before synthesis.The book provides a wealth of valuable information and: - Presents an overview of recent developments in QSAR methodologies along with a brief history of QSAR- Covers the available web resource tools and in silico techniques used in virtual screening and drug discovery processes, compiling an extensive review of web resources in the following categories: databases related to chemical compounds, drug targets, and ADME/toxicity prediction; molecular modeling and drug designing; virtual screening; pharmacophore generation; molecular descriptor calculation software; software for quantum mechanics; ligand binding affinities (docking); and software related to ADME/toxicity prediction- Reviews the rm2 as a more stringent measure for the assessment of model predictivity compared to traditional validation metrics, being specifically important since validation is a crucial step in any QSAR study- Presents linear model improvement techniques that take into account the conformation flexibility of the modeled molecules- Summarizes the building processes of four different pharmacophore models: common-feature, 3D-QSAR, protein-, and protein-ligand complexes- Shows the role of different conceptual density functional theory based chemical reactivity descriptors, such as hardness, electrophilicity, net electrophilicity, and philicity in the design of different QSAR/QSPR/QSTR models- Reviews the use of chemometrics in PPAR research highlighting its substantial contribution in identifying essential structural characteristics and understanding the mechanism of action- Presents the structures and QSARs of antimicrobial and immunosuppressive cyclopeptides, discussing the balance of antimicrobial and haemolytic activities for designing new antimicrobial cyclic peptides- Shows the relationship between DFT global descriptors and experimental toxicity of a selected group of polychlorinated biphenyls, exploring the efficacy of three DFT descriptors- Reviews the applications of Quantitative Structure-Relative Sweetness Relationships (QSRSR), showing that the last decade was marked by an increase in the number of studies regarding QSAR applications for both understanding the sweetness mechanism and synthesizing novel sweetener compounds for the food additive industryThe wide coverage makes this book an excellent reference for those in chemistry, pharmacology, and medicine as well as for research centers, governmental organizations, pharmaceutical companies, and health and environmental control organizations.

Every day, millions of people are unaware of the amazing processes that take place when using their phones, connecting to broadband internet, watching television, or even the most basic action of flipping on a light switch. Advances are being continually made in not only the transmission of this data but also in the new methods of receiving it. These advancements come from many different sources and from engineers who have engaged in research, design, development, and implementation of electronic equipment used in communications systems. This volume addresses a selection of important current advancements in the electronics and communications engineering fields, focusing on signal processing, chip design, and networking technology. The sections in the book cover: >Microwave and antennasCommunications systemsVery large-scale integrationEmbedded systemsIntelligent control and signal processing systems

Energy is one of the prime needs of the modern world, and energy demands have been rapidly increasing in the recent years owing to rapid advancements in industrialization and population explosion. Conventional fossil fuels are being depleted at rapid rates, and the use of conventional sources such as coal or nuclear sources cause several hazards to the environment. New sources of fuel, such as bioenergy, are an ideal option for fulfilling ever-increasing energy demands. This important book offers an exploration of these alternate fuel sources, including biohydrogen, microbial fuel cells, bioethanol, and biodiesel production, focusing on the challenges and factors hindering the real-time application of these bioenergy sources.Researchers all over the world are working in this energy sector, and this has led to drastic improvements in bioenergy research. However, the technology gap between research and industrial application still exists. This important book offers engineers and technologists from different disciplines valuable information on this multifaceted field. The field of bioenergy is interdisciplinary, requiring the knowledge of biologists, chemists, physicists, and engineers. Exploring the current trends and future prospects for biofuels, the information presented in this book will be valuable to the international industrial community for identifying new options to circumvent problems that exist in bioenergy applications. Topics include: - Thermophilic biohydrogen production- Bio-hydrogen production- Microbial fuel cells as a promising alternative energy source- Microbial fuel cell applications- Potential of Pscillatoria annae in producing bioethanol - Potential of lignocellulosic biofuels - Biodiesel production- Reactor designs for biodesel production- Long-term storage stability of Pongamia pinnata and Jatropha curcus biodiesel

Child trauma and violence is not an issue that is constrained to one nationality or one ethnicity. A staggering number of children around the world are subjected to violence and abuse, both domestic and political. The current volume examines the issue of developmental trauma from a variety of viewpoints, including sociological, epidemiological, genetic, and psychiatric. The chapters contained within are broken into the following sections: Child neglect and violence from an international perspective The effects of war and armed conflict on children's health and development The impact of childhood trauma on mental and physical health into adulthood Case studies of interventions that provide possibilities for treatment in a variety of different contextsWritten by a researcher from Harvard Medical School and Children's Hospital (Boston), this book provides an important resource for understanding violence as an almost ubiquitous presence in children's lives around the world, as well as offering directions for treatment and interventions. This book is an important resource for researchers, counselors, psychologists, child advocates, and anyone who seeks to understand how adversity in childhood affects a person's entire life.

This book focuses on the recent trends in micro- and nano-structured polymer systems, particularly natural polymers, biopolymers, biomaterials, and their composites, blends, and IPNs. This valuable volume covers the occurrence, synthesis, isolation, production, properties and applications, modification, as well as the relevant analysis techniques to reveal the structures and properties of polymer systems. Biobased polymer blends and composites occupy a unique position in the dynamic world of new biomaterials. The growing need for lubricious coatings and surfaces in medical devices-an outcome of the move from invasive to noninvasive medicines and procedures-is playing a major role in the advancement of biomaterials technology. Natural polymers have attained their cutting-edge technology through various platforms, and this book presents a multitude of information about them. Topics include biopolymer-synthetic systems, nanomaterial-polymer structures, multi-characterization techniques, polymer blends and composites, polymer gels and polyelectrolytes, and many other interesting aspects of interests to researchers.This book will be valuable to scientists, physicians, pharmacists, engineers, and other specialists in a variety of disciplines, both academic and industrial.

This title includes a number of Open Access chapters.Childhood obesity is a major public health crisis nationally and internationally. This insightful compendium provides valuable information and assesses the research foundations behind several school initiatives to help combat the epidemic of obesity in children and adolescents, particularly using interventions to increase physical activity. The book looks at the issue from three levels: first, the effects of unhealthy eating and lack of exercise on a number of health outcomes in children and adolescents; second, successful small- and large-scale school-based interventions; and finally, synthesis of current literature and translation into specific guidelines and recommendations. Specific topics addressed in the book include: - The appeal and benefits of outdoor versus indoor activity- Cultural differences in physical activity - Successful interventions and their continued success, or lack of, after several years- The roles of family and community interventions- Staff involvement in children's physical activities- Specific programs, such as Plant Health, an antismoking intervention with unintended obesity intervention- Establishing healthy habits in youth This research provides schools with a strong foundation for implementing policies and practices that support healthy eating and regular physical activity. In the process, educators will be ensuring the best possible chance for increasing students' academic success, improving both physical and mental health, and decreasing the risk for myriad chronic diseases.

This title includes a number of Open Access chapters.Child obesity is a serious condition that affects children around the world in growing numbers. With obesity comes an increased risk of other chronic diseases as well, making it even more important to understand and treat this condition from a variety of angles. This current volume seeks to understand the phenomenon of child obesity and presents a range of viewpoints on its prevalence, causes, and treatments. The different sections contained within explore the following topics: - The worldwide prevalence of childhood obesity and its growing effect on children- The causes of childhood obesity and the complex interactions of genetic, environmental, social, and medical factors that contribute to its development- Proposed treatments, some intervention-based and others that aim to change how food is marketed and sold to youthThis reference volume offers a comprehensive and thorough guide to a field that is rapidly expanding and points to new directions in research and public policy. Edited by a doctor with extensive experience as a researcher, writer, and medical practitioner, The Childhood Obesity Epidemic is an authoritative and easy-to-use reference that provides resources for researchers in the field, students, and anyone who wishes to gain an overview to this important field of study.

Land represents an important resource for the economic life of a majority of people in the world. The way people handle and use land resources impacts their social and economic well-being as well as the sustained quality of land resources. Land use planning is also integral to water resources development and management for agriculture, industry, drinking water, and power generation. This valuable work brings to the forefront the state of practice of land use planning in India, highlighting governmental programs and research with wide-ranging chapters on important topics. Covering various agro-ecosystem, including irrigated, rainfed, coastal, semi-arid, arid (drylands), and hill and mountain (temperate) regions, this volume discusses a variety of issues related to sustainable agriculture and rural development. Chapters address the following questions: -What are the sources, scales, and quality of land resources and land use data for efficient planning- Which are the agroecological systems hot spots that are have been degraded? How can these areas be rejuvenated in terms of quality?- What should be the unit of planning for a holistic approach for the conservation and efficient use of natural resources at different administrative levels and domains?- What are the roles of state land use boards and district planning committees?- How can various programs be integrated and implemented by central and state agencies?- What are the technologies, new policies, and support systems required to address sustainable land use?- What are the legal issues?- What should be the role of communities in planning for poverty alleviation and integrated planning for sustainable agriculture based livelihoods?- What is the role GIS in sustainable agriculture and rural development?With high population growth, endemic poverty, and weak existing institutional capacity for land management, India (and other regions of the world) require strong scientific and strategically important land use policies and methods for sustainable development. This book helps to show the way. This volume is being published in association with the Centre for Agrarian Studies and Disaster Mitigation of the National Institute of Rural Development and Panchayati Raj (NIRD and PR).

This important volume, the ninth in the Research Advances in Sustainable Micro Irrigation book series, provides an invaluable addition to the literature and knowledge on the ever-growing need for sustainable irrigation for agricultural crops in many water-scarce parts of the world. The book specifically covers advances in fertigation for water management in general as well as for specific crops, such as peaches, maize, and citrus crops. Specific topics include: - The design of various surface and subsurface water emitters- Using information from weather stations for irrigation purposes- Ultra low drip irrigation technology- The management of weeds in crops using micro irrigation- New technology and advances in fertigationWith chapters from researchers and practitioners in agricultural engineering, water research and technology, soil conservation, and other fields, this compendium provides a wealth of useful information that can be put into practice to enhance crop production.

This volume contains peer-reviewed chapters and original research on chemistry and its broad range of applications in chemical engineering. Covering both theoretical and practical applications of modern chemistry, the book presents a different aspects of chemistry and chemical engineering. The book includes the most significant new research papers and other original contributions on the structure of single molecules and radicals, molecular assemblies, gases, liquids (including water and solutions), amorphous and crystalline solids, surfaces, films and nanoparticles (including inorganic, organic and organometallic compounds), molecular and polymeric materials, single crystals, and minerals. The aim of this multidisciplinary book is to promote communication and dialogue among researchers, scientists, engineers, and policymakers working in the areas of modern chemistry and chemical engineering and who deal with all structural aspects of modern chemistry and chemical engineering. The research provided here will be especially valuable to those interested in the principles of chemical bonding and matter organization, the impact of structural aspects on a chemical property or transformation, and the application of the newest physical methods in chemical structure research.

This title includes a number of Open Access chapters. Mental illnesses are often difficult to treat. They do not just affect individuals, they are rooted within communities and affect many other aspects of individuals' social and physical lives as well. This book examines mental health specifically in adolescents, exploring how mental illnesses interface with communities, schools, families, and peers. It also explores the connotations for educators, social workers, medical professionals, and public policymakers. The various sections cover the following topics: - The interactions of adolescent mental health with the broader cultural and socioeconomic communities - The interactions of the educational community on adolescent mental health - The impact of peer and family relationships on adolescent mental health - Case studies of successful community interventions This accessible reference volume offers a comprehensive guide to the multifaceted field of adolescent mental health. Edited by a physician at Boston Children's Hospital, this book is an important resource for educators, parents, social workers, researchers, clinicians, public policy makers, and all who wish to understand the complex interactions involved in comprehending and treating mental health disease in young people.

This title includes a number of Open Access chapters.The research contained in this valuable compendium offers a much-needed perspective on one of the most dangerous health crises our world faces today: obesity. Obesity has become an epidemic, a fact frequently discussed in the media, with many references to both childhood and adult obesity. These discussions, however, overlook an important demographic: the adolescent who is obese or overweight. The authors offer critical insights into the forces and factors that result in the numerous metabolic and psychological consequences of adolescent obesity.The book delves into the prevalence, causes and correlates, and implications and consequences of adolescent obesity, and goes on to present considerations for future action. The research covers many of the causes of adolescent obesity, including increased consumption of high carbohydrate snacks; eating too much, too fast, and too frequently; eating high-fat, cheap, convenient, and readily assessable foods; increased sedentary activities, such as TV watching and video games, accompanied by decreased physical activity; parents' and schools' lack of nutrition vigilance; and the commercial incentives to sell calorie-dense foods aggressively and relentlessly.Edited by an eminent doctor and professor, The Complexity of Adolescent Obesity is an easily accessible and well-organized volume that offers vital research context for policymakers, educators, medical providers, and families.

This title includes a number of Open Access chapters.This collection of timely chapters presents a nuanced study of environmental toxins and the risks they pose to children's development. The book details the impact of a number of commonplace environmental toxins, focusing on everyday exposure to tobacco smoke, lead, pesticides, and flame retardants. There is growing recognition that the impact of the environment on children's health is of critical importance for both current and future generations. In the last half-century, thousands of chemicals have been introduced into the environment with limited-although growing-research on the consequences of exposure. It has been proven that children and adolescents are far more vulnerable than adults to these environmental toxins by virtue of children's behaviors, higher metabolic rate, greater skin area relative to their volume, and still developing organ systems. Increased number of ear infections, poor asthma control, and learning disabilities are just some of the adverse outcomes that have been noted.This well-researched book: - Presents detailed information on why children are more vulnerable to everyday toxins- Discusses why new approaches to medical care are necessary that take into account children's unique physiology and development - Offers well-defined research on tobacco smoking on prenatal development as well as children's exposure to tobacco smoke during their early years, particularly the evidence of asthma and asthma-like symptoms- Examines the possible health effects of children born to mothers living in areas of natural gas development - Looks at the health effects of childhood exposure to environmental lead, using GIS technology to study areas of potentially high lead concentrations- Discusses the possible effects of agricultural pesticides on children's health during gestation- Presents studies on prenatal and adolescent exposure to PBDEs used as flame retardants in many household and commercial products to prevent fireThis valuable book, edited by a pediatric clinician at Boston's Children's Hospital, provides a wealth of information on this important issue. The book concludes with an article by the World Health Organization, which offers a practical and comprehensive summary of a series of action steps. The book aims to create greater awareness to spur additional research, provide vital information to clinicians, and send a powerful message to government officials, putting pressure on them to develop policies that improve the quality of the environment and spare children the detrimental effects of such exposures.

This book focuses on best management practices for drip irrigated crops. It cover irrigation methods, scheduling of micro irrigation, and mulching and crop performance. Micro irrigation techniques with diverse crops are discussed, including sweet pepper, chili, tomatoes, cauliflower, wheat, sweet peas, sugarcane, and potatoes. The performance of

The aim of this new compendium is to provide a solid understanding of the recent developments in advanced polymeric materials from macro- to nano-length scales. Composites are becoming more important because they can help to improve our quality of life, such as being put into service in flight vehicles, automobiles, boats, pipelines, buildings, roads, bridges, and dozens of other products, including medical products. The chapters cover a multitude of important advances, including explanations of the significance of the new fillers, like graphene and carbon nanotubes, in different matrix systems. Coverage of the application of these materials in biological and others fields also makes this book unique. Topics include advances on the processing, properties, recyclability, and reparability, and applications for polymer matrix composites, ceramic matrix composites, carbon matrix composites, wood-based composites, biocomposites, ecocomposites, nanocomposites, and more.

This title includes a number of Open Access chapters.This book serves as an introduction to genomics, proteomics, and transcriptomics, putting these fields in relation to human disease and ailments. The various chapters consider the role of translation and personalized medicine, as well as pathogen detection, evolution, and infection, in relation to genomics, proteomics, and transcriptomics. The topic of companion diagnostics is also covered. The book is broken into five sections. Part I examines the connection between omics and human disease. Part II looks at the applications for the fields of translational and personalized medicine. Part III focuses on molecular and genetic markers. Part IV describes the use of omics while studying pathogens, and Part V examines the applications for companion diagnostics. The book: - Introduces genomics, proteomics, and transcriptomics in relation to human disease and ailments - Considers the role of translation and personalized medicine in relation to genomics, proteomics, and transcriptomics - Covers molecular and genetic markers - Considers the role of genomics, proteomics, and transcriptomics in relation to pathogen detection, evolution, and infection - Covers companion diagnostics in relation to genomics, proteomics, and transcriptomics clinical applications and research

This book is a comprehensive review of the instrumental analytical methods and their use in environmental monitoring site assessment and remediation follow-up operations.The increased concern about environmental issues such as water pollution, air pollution, accumulation of pollutants in food, global climate change, and effective remediation processes necessitate the precise determination of various types of chemicals in environmental samples. In general, all stages of environmental work start with the evaluation of organic and inorganic environmental samples. This important book furnishes the fundamentals of instrumental chemical analysis methods to various environmental applications and also covers recent developments in instrumental chemical methods.Covering a wide variety of topics in the field, the book: - Presents an introduction to environmental chemistry- Presents the fundamentals of instrumental chemical analysis methods that are used mostly in the environmental work. - Examines instrumental methods of analysis including UV/Vis, FTIR, atomic absorption, induced coupled plasma emission, electrochemical methods like potentiometry, voltametry, coulometry, and chromatographic methods such as GC and HPLC- Presents newly introduced chromatographic methodologies such as ion electrophoresis, and combinations of chromatography with pyrolysis methods are given- Discusses selected methods for the determinations of various pollutants in water, air, and landReaders will gain a general review of modern instrumental method of chemical analysis that is useful in environmental work and will learn how to select methods for analyzing certain samples. Analytical instrumentation and its underlying principles are presented, along with the types of sample for which each instrument is best suited. Some noninstrumental techniques, such as colorimetric detection tubes for gases and immnosassays, are also discussed.

This title includes a number of Open Access chapters.The rate of identification of children with neurobiological disabilities has been on the increase in recent years. Millions of dollars in research are being spent to understand the factors influencing these increases. The articles within this compendium shed vital light on this issue, confirming that various "ordinary" chemical hazards-of the sort encountered by countless children in their everyday lives-are having serious impacts on development. This volume investigates the impact of exposure to tobacco smoke, household chemicals, lead, agricultural toxins, and flame retardants.

This book will be a major resource for all academic researchers and practitioners interested in issues dealing with the development of tourism, its potential and challenges, and policy and regulatory issues in the Central Asian countries of Kazakhstan, Uzbekistan, Turkmenistan, Kyrgyzstan, and Tajikistan. These countries are gaining more attention as emerging destinations. There is limited research that focuses on these countries with respect to their potential and characteristics as tourism destinations. This book aims to be an invaluable source for both practitioners and academicians who are in international marketing and tourism. The central Asia region (also termed the Silk Road region) as an emerging destination is ripe for future tourism development. The region is rich with historical, cultural, and natural beauty that could provide significant utility to many potential visitors. This book brings together key writings on this topic in a single resource.