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Presents a comprehensive account of established protectingΓÇôgroupΓÇôfree synthetic routes to molecules of medium to high complexity This book supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an ΓÇ£ideal synthesisΓÇ¥ and back the global need of practicing green chemistry. The only resource of its kind to focus entirely on protectingΓÇôgroupΓÇôfree synthesis, it is edited by a leading practitioner in the field, and features enlightening contributions by top experts and researchers from across the globe. The introductory chapter includes a concise review of historical developments, and discusses the concepts, need for, and future prospects of protectingΓÇôgroupΓÇôfree synthesis. Following this, the book presents information on protectingΓÇôgroupΓÇôfree synthesis of complex natural products and analogues, heterocycles, drugs, and related pharmaceuticals. Later chapters discuss practicing protectingΓÇôgroupΓÇôfree synthesis using carbohydrates and of glycosyl derivatives, glycolΓÇôpolymers and glycoΓÇôconjugates. The book concludes with a chapter on latent functionality as a tactic toward formal protectingΓÇôgroupΓÇôfree synthesis. A comprehensive account of established protectingΓÇôgroupΓÇôfree (PGF) synthetic routes to molecules of medium to high complexity Benefits total synthesis, methodology development and drug synthesis researchers Supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an ΓÇ£ideal synthesisΓÇ¥ and support the global need of practicing green chemistry Covers a topic that is gaining importance because it renders syntheses more economical ProtectingΓÇôGroupΓÇôFree Organic Synthesis: Improving Economy and Efficiency is an important book for academic researchers in synthetic organic chemistry, green chemistry, medicinal and pharmaceutical chemistry, biochemistry, and drug discovery.
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