Bøker av A. A. Akhrem

The numerous methods for obtaining steroids developed at the present time can be divided into four main groups: isolation from natural sources, microbiological synthesis, partial synthesis from natural raw material already containing the steroid skeleton, and, finally, total chemical synthesis from precursors of com paratively simple structure.

Birch reduction (see reviews [1-5]) is the name given to the reaction of unsaturated organic compounds with alkali metals and alcohols in liquid am monia. - i T 1 3 +--"'( a) , , ,e (NHa) NH 3) + ROH ----+ () ll. (NHa) A H H 4) H H 5) ')', ",,\\+ + RO" ~ Q + 110M,,,,,, / (NHa) . (NH:,) Q H H Ii Ij H H H H H+ X/~H M,l