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Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Volume 168 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer''s disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, Propagation and removal of cerebral amyloid angiopathy, and much more. Includes comprehensive coverage of molecular biologyPresents ample use of tables, diagrams, schemata and color figures to enhance the reader''s ability to rapidly grasp the information providedContains contributions from renowned experts in the field

Cancer Immunotherapy, Volume 165 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to different approaches to cancer immunotherapy, with this release focusing on TNFR2 in cancer immunology and immunotherapy, From the Hellstrom paradox towards cancer cure, CAR T-cell treatment of T-cell malignancy , Immunotherapy of pancreatic cancer, Cancer stem cell immunology/immunotherapy, Cytokine release syndrome, Tumor cell-based mechanisms of resistance to immune attack, and Mushroom compounds in cancer immunotherapy.Includes comprehensive coverage of molecular biologyPresents ample use of tables, diagrams, schemata and color figures to enhance the reader''s ability to rapidly grasp the information providedContains contributions from renowned experts in the field

G Protein Signaling Pathways in Health and Disease, Volume 161 in the Progress in Molecular Biology and Translational Science series, provides informative and exciting monographs on a wide variety of research topics related to G Protein Signaling Pathways in Health and Disease. The series gives in-depth knowledge on the important molecular biological aspects of organismal physiology and function, along with insights on how this knowledge can be applied to understand and ameliorate human disease. This updated release covers Diseases associated with mutations in CNGA3, Mutations in arrestins, Diseases caused by mutations in GPR101, Diseases caused by mutations in lutropin receptor, and much more.

Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis of Cancers and Other Diseases: Past, Present and Future, Desialylation in Diseases and its Application in Diagnostic and Therapeutic Development, Proteoglycans as Miscommunication Biomarkers for Cancer Diagnosis, Fucosylation in Cancer Biology and Its Clinical Applications, Retrospective Analysis of Glycan-Related Biomarkers Based on Clinical Laboratory Data in Two Medical Centers, and many related topics. Includes comprehensive coverage of molecular biologyPresents ample use of tables, diagrams, schemata and color figures to enhance the reader''s ability to rapidly grasp the information providedContains contributions from renowned experts in the field

Matrix Metalloproteinases and Tissue Remodeling in Health and Disease Part I: Cardiovascular Remodeling is the latest volume in the Progress in Molecular Biology and Translational Science series. This volume is the first part of a thematicáand contains up-to-date information on the biology and function of matrix metalloproteinases, and how their effects on tissue remodeling are altered in diseases of the cardiovascular, pulmonary, and musculoskeletal systems and other tissues and organs, as well as cancer.á Contributors include prominent scientists and highly-recognized experts with major accomplishments in the research field of matrix metalloproteinases.Focuses on matrix metalloproteinases and their role in tissue remodeling under physiological and pathological conditionsContains up-to-date information on matrix metalloproteinases that is clearly presented in a concise fashion with helpful illustrations and supporting referencesIncludes comprehensive reviews written by prominent scientists and highly-recognized experts in the field of matrix metalloproteinases and tissue remodeling

Molecular and Cellular Changes in the Cancer Cell,the latest volume in the Progress in Molecular Biology and Translational Science series, includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. This volume examines some of the latest advances, highlighting some of the most important molecular and cellular alterations and environmental influences that collectively cause a normal cell to become cancerous. Special emphasis is given to changes that take place at the molecular and cellular level.Comprehensive and up-to-date survey of current knowledge on the cancer cellIncludes the latest advances and the most important molecular and cellular alterations and environmental influences collectively causing cells to become cancerousWritten by leading experts in the field

Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. This title discusses various discoveries, approaches, and ideas in this field.

Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume integrates toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships.

Reviews various developments in the field of membrane proteins. This title discusses different discoveries, approaches, and ideas in the field and reviews how they are being used to develop new drugs. It is suitable for researchers involved in molecular biology and related fields.

Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive organs. This title reviews the research and developments in this field. It is suitable for researchers involved in molecular biology and related fields.

Includes discussion on roles of Chromatin remodeling proteins in nuclear receptor signaling, and ANCCA regulator in cancer. This resource offers research on the progesterone receptor action in leiomyoma and endometrial cancer and roles of the ubiquitin protein system in nuclear hormone receptor signaling.