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This volume describes high-throughput approaches to a series of robust, established methodologies in molecular genetic studies of population samples.

Mammalian cell products such as monoclonals and cytokines dominate the biopharmaceutical industry. This book explores the interactions between biological, biochemical and engineering principles in processes derived from cell cultures.

With the end of the Human Genome Project in sight, the next important step is to determine the function of genes. Proteome Research is an important approach to this study and is the first book to comprehensively cover the application of two-dimensional electrophoresis, the central methodology in proteome research.

Paul Popescu, Directeur de Recherche at INRA, has also played a promi nent part in the development of animal cytogenetics, especially in domestic animals. She showed the fascinating correspondence between bovine and human chromosomes and the com pared gene maps of domestic bovidae.