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A collection of refereed papers from a six-week workshop on statistics in the health sciences, that brought together theoretical and applied statisticians from universities, medical and public health schools, government and private research institutions, and pharmaceutical companies involved in prediction problems in the life and social sciences and in diagnostic and screening tests. A number of papers with applications were presented and particularly lively discussions ensued involving the critical issues and difficulties in using and interpreting diagnostic tests and implementing mass screening programs. The prediction or controlling future events, such as survival, comparative survival and survival post intervention for a disease or even for certain biological or natural events was also represented by participants who presented work that devised predictive methodology for a variety of problems mainly from a Bayesian perspective.

The articles collected in this volume represent the contributions presented at the IMA workshop on "Dynamics of Algorithms" which took place in November 1997. The workshop was an integral part of the 1997 -98 IMA program on "Emerging Applications of Dynamical Systems." The interaction between algorithms and dynamical systems is mutually beneficial since dynamical methods can be used to study algorithms that are applied repeatedly. Convergence, asymptotic rates are indeed dynamical properties. On the other hand, the study of dynamical systems benefits enormously from having efficient algorithms to compute dynamical objects.

The Institute for Mathematics and its Applications (IMA) devoted its 1997-1998 program to Emerging Applications of Dynamical Systems. Dynamical systems theory and related numerical algorithms provide powerful tools for studying the solution behavior of differential equations and mappings. In the past 25 years computational methods have been developed for calculating fixed points, limit cycles, and bifurcation points. A remaining challenge is to develop robust methods for calculating more complicated objects, such as higher- codimension bifurcations of fixed points, periodic orbits, and connecting orbits, as well as the calcuation of invariant manifolds. Another challenge is to extend the applicability of algorithms to the very large systems that result from discretizing partial differential equations. Even the calculation of steady states and their linear stability can be prohibitively expensive for large systems (e.g. 10_3- -10_6 equations) if attempted by simple direct methods. Several of the papers in this volume treat computational methods for low and high dimensional systems and, in some cases, their incorporation into software packages. A few papers treat fundamental theoretical problems, including smooth factorization of matrices, self -organized criticality, and unfolding of singular heteroclinic cycles. Other papers treat applications of dynamical systems computations in various scientific fields, such as biology, chemical engineering, fluid mechanics, and mechanical engineering.

Inverse problems in wave propagation occur in geophysics, ocean acoustics, civil and environmental engineering, ultrasonic non-destructive testing, biomedical ultrasonics, radar, astrophysics, as well as other areas of science and technology. The papers in this volume cover these scientific and technical topics, together with fundamental mathematical investigations of the relation between waves and scatterers.