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This book provides the practicing physician with a practical approach to the diagnosis, evaluation and management of headache disorders based on lessons learned from real-life headache patients. A wide spectrum of headache types is covered, including both primary and secondary headache disorders.

This book provides up-to-date information on all aspects of the comorbidities that are associated with the headache disorders commonly seen in the primary care and hospital settings, including migraine, tension-type headache, and cluster headache.

This book provides up-to-date information on all aspects of the comorbidities that are associated with the headache disorders commonly seen in the primary care and hospital settings, including migraine, tension-type headache, and cluster headache.

This book discusses interventional treatment options on intractable (drug resistant) headache patients and extended headache attacks and extensively reviews the reasons behind treatment failure in intractable headaches, offering potential solutions based on clinical black holes of headache outpatient practice.

This book provides essential insights into the current state of knowledge regarding the main aspects of cluster headache and trigeminal autonomic cephalgias.

This book addresses all aspects of neuromodulation therapy in the management of headache and facial pain disorders, paying particular attention to the application of this rapidly growing and fascinating therapy to different forms of headache and facial pain conditions.

Roughly one in every five patients referred to a neurologist suffers from headaches; the majority have migraines. Although headache specialists understand migraine on a clinical basis, the pathophysiological changes that provoke and accompany the development of a migraine attack continue to elude us.Several decades have passed since the pioneering electroencephalographic study by Golla and Winter (1959), which underscored the role of abnormal rhythmic activities in migraine. Since then, there have been substantial advances in the field; a wealth of neurophysiological studies has enriched our understanding of the pathophysiological facets of the migraine pathology. Virtually every known technique of clinical electrophysiology has since been used to study the migraine brain and, more recently, new neurophysiological tools have been added to the arsenal. Nevertheless, applying the principles of peripheral and central neuromodulation offers a promising way to transfer the principles of synaptic plasticity to the patient¿s bedside.This book belongs to the Headache Series endorsed by the European Headache Federation. Written by internationally recognized experts in their respective fields, it covers all aspects of clinical neurophysiological methods that represent significant advances in our understanding of the pathophysiology of migraine. It will offer a valuable toolkit for beginners, and a reference guide for experts.

This book provides essential insights into the current state of knowledge regarding the main aspects of cluster headache and trigeminal autonomic cephalgias.

Intended to promote a more appropriate and modern therapeutic approach to migraine management, this book is the first to deal with monoclonal antibodies in this context. Authored by the most respected migraine experts from around the globe and drawing on the lessons learned in both clinical trials and clinical practice, it reviews the current state of knowledge on this important therapeutic innovation, which has produced impressive data in randomized controlled trials, and the efficacy and safety of which have been confirmed in day-to-day real-world use. Given its scope, the book will appeal to a broad range of specialists, including pharmacologists, clinical pharmacologists, neurologists and internists, but also to residents and medical students.

Published in the series Headache, endorsed by the European Headache Federation, this is the first book on the novel synthetic treatment of migraine with ditans (lasmiditan) and gepants (atogepant, ubrogepant, rimegepant, vazegepant). These drugs will provide additional options for people with migraine put at risk of side effects by other medications or with unsatisfactory response to previous drugs. There is now a sufficient amount of literature published to interest a wide multidisciplinary readership (general physicians, general neurologists, clinical psychologists, neurologists in training, and medical students) facing every day this burdensome disorder in their clinical practice. The book aims therefore at offering an overview of these new drugs for both acute and prophylactic treatments of migraine, covering studies on clinical evidence, tolerability, and the different stages of clinical development.

This book provides an overview of planning and examining the methodology, analytic issues, primary and secondary endpoints and outcomes in headache trials. Throughout the book, guidance on how to design a high quality study and how to evaluate which study has relevant scientific qualification is discussed in detail. Clinical scales and patient related outcome measures (PROMs) to exclude secondary headaches, to diagnose primary headache disorders, to evaluate patients¿ health-related quality of life, to detect psychiatric comorbidities, to assess patients¿ headache-related disability and to monitor patients¿ treatment optimization are clearly and concisely outlined in the chapters. Clinical Scales for Headache Disorders highlights the components for planning an effective headache study including interpretation of primary and secondary endpoints, common clinical scales, PROMs and their clinical reliability and validation. Both clinicians and researchers willfind this book to be a useful tool for their medical and academic practices on headache and migraine.

This book provides a physician¿s pathfinder for COVID specific headache disorders as well as general headache practice in a pandemic era. Practical solutions to headache management at every level are highlighted, along with the changing nature of previous headache disorders under lockdown conditions.Headache Disorders in Pandemic Conditions examines the specific nature of headache symptoms during COVID-19 infection, the secondary causes of COVID-specific headache disorders and practical issues of previous known headache disorders during a pandemic. The book also explores the effect of lockdown on headache management and changes in headache education, practice, risks and guidelines. Neurologists, headache specialists, general practitioners, medical students and residents will find this book to be a practical and clear guide to Covid-19 specific headache disorders in clinical practice.