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This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.

This book summarizes the recent advancements for visualized medicine in terms of fundamental principles, rapidly emerging techniques and developing frontiers. Especially with the combination of artificial intelligence (AI), medical imaging agents and medical robots, smart medical technologies have been innovated and applied to the clinical uses to serve the fatal human diseases diagnosis, treatment, prognosis and data analysis. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare, and will enable precision medicine and precision surgery further intuitively detectable, smartly analyzable and accurately operational. This book will discuss and conclude: 1) state-of-the-art definition of visualized medicine; 2) advanced techniques and clinical applications of visualized medicine in the past decade; 3) novel frontiers and brand-new technologies, e.g. artificial intelligence (AI), surgical robots, etc. 4) revolutionary impacts on disease diagnosis, treatments and prognosis; 5) future challenges and perspectives.

Cell to Organ: Electromechanical Activation.- 1 Regulation of Intracellular Calcium in Cardiac Muscle.- 2 Neuromodulation of Calcium Current by Extracellular ATP in Isolated Ventricular Myocytes.- 3 Intracellular Calcium and Myocardial Function during Ischemia.- 4 Intracellular Signaling in Vascular Smooth Muscle.- 5 Myocardial Energetics.- 6 Mechanisms of Endocardial Endothelium Modulation of Myocardial Performance.- 7 Calcium Kinetic and Mechanical Regulation of the Cardiac Muscle.- 8 Cellular Responses to Electrical Stimulation: A Study Using a Model of the Ventricular Cardiac Action Potential.- 9 Excitation-Contraction Coupling and Contractile Protein Function in Failing and Nonfailing Human Myocardium.- Mechanics and Microcirculation.- 10 Estimation of Myocardial Mechanical Properties with Dynamic Transverse Stiffness.- 11 Intramyocardial Mechanical States: Vessel-Interstitium-Muscle Interface.- 12 Myocardial Mechanics and Coronary Flow Dynamics.- 13 Modeling of Coronary Capillary Flow.- Microstructure: Mechanics and Microcirculation.- 14 Models for Coronary Pressure-Flow Relationships.- 15In VivoMyocardial Microcirculation: Evaluation with a Whole-Body X-Ray CT Method.- 16 Endocardial Coronary Microcirculation of the Beating Heart.- 17 Distribution and Control of Coronary Microvascular Resistance.- 18 Theoretical Analysis of Coronary Blood Flow and Tissue Oxygen Pressure-Control.- Microcirculation and Metabolic Transport.- 19 Adenosine Coronary Vasodilation during Hypoxia Depends on Adrenergic Receptor Activation.- 20 Chaos in Cardiac Signals.- 21 Intramyocardial Fluid Transport Effects on Coronary Flow and Left Ventricular Mechanics.- 22 Metabolic Protection of Post-Ischemic Phosphorylation Potential and Ventricular Performance.- 23 Metabolic and Mechanical Control of the Microcirculation.- Remodeling of Muscle and Vessels.- 24 Asymmetrical Changes in Ventricular Wall Mass by Asynchronous Electrical Activation of the Heart.- 25 Ventricular Remodeling after Myocardial Infarction.- 26 Arterial Remodelling after Percutaneous Transluminal Balloon Angioplasty.- 27 Structural and Functional Remodeling of Poststenotic Arteries in the Rat.- 28 Myocardial Collagen and Its Functional Role.- Cardiac Function and Circulation.- 29 Ventricular-Arterial Interaction: Cardiac Effects of Mean versus Pulsatile Arterial Load.- 30 The Veins and Ventricular Preload.- 31 Why Smaller Animals Have Higher Heart Rates.- 32 Feedback Effects in Heart-Arterial System Interaction.- Integrated Analysis.- 33 The Relationship between Altered Load and Impaired Diastolic Function in Conscious Dogs with Pacing Induced Heart Failure.- 34 Interactions: The Integrated Functioning of Heart and Lungs.- 35 Carotid-Cardiac Interaction: Heart Rate Variability during the Unblocking of the Carotid Artery.- 36 Right and Left Ventricle Interaction and Remodeling in Congenital Heart Disease.- 37 Macroscopic Three-Dimensional Motion Patterns of the Left Ventricle.- 38 Cardiovascular Flow Velocity Measurements by 2D Doppler Imaging for Assessment of Vascular Function.- The Editors.- Contributors.

Chemistry. Tetrahydrobiopterin Dependent Hydroxylases. Tetrahydrobiopterin Regenerating Enzymes. Tetrahydrobiopterin Biosynthesis. Tetrahydrobiopterin Regulation. Tetrahydrobiopterin Deficiency. Nitric Oxide Synthase. Other Functions of Tetrahydrobiopterins. Molybdopterin Cofactors. Synthesis and Biological Evaluation of AntiFolates. Dihydrofolate Reductase. Thymidylate Synthase. Folylpolyglutamate Synthetase and Hydrolase. OneCarbon Metabolism. Folate Nutrition and Transport. 165 articles. Index.

Methods and Procedures for Preparing Resealed Erythrocytes: IHP Entrapment into Human Erythrocytes; A. Mosca, et al. Resealed Erythrocytes as a Tool for Basic Studies: ATP Monitoring in Human Red Blood Cells with Luciferase Introduced Intracellularly; V.M. Vitvitsky, et al. Resealed Erythrocytes as a Cellular Bioreactors: Acetaldehayde Oxidation by Aldehyde Dehydrogenase Loaded Erythrocytes; P. Ninfali, et al. Resealed Erythrocytes as Advanced Drug Delivery Systems: Erythrocytes as Carriers of New Anti-Opioid Prodrugs; S. Noel-Hocquet, et al. Site Specific Targeting of Resealed Erythrocytes: Erythrocytes as Carriers of Ricin A Chain; N. Chestier, et al. Human and Veterinary Studies Using Resealed Erythrocytes: Susceptibility of Carrier Erythrocytes to a Natural Hemolytic System; H.J. Kirch, et al. 36 additional articles. Index.

A Perspective of Resonant Tunneling; L.L. Chang. Materials and Band-Structure Effects: Epitaxial Growth of Atomically Smooth GaAs/AlxGa1xAs Interfaces for Resonant Tunneling; K. Ploog. MBE Growth of High Performance GaAs/GaAlAs and InGaAs/GaAlAs Double Barrier Quantum Well Structures for Resonant Tunneling Devices; H. Riechert, et al. Tunneling in Polytype InAs-AlSb-GaSb Heterostructures; K.F. Longenbach, et al. Scattering and Dynamic Effects: Scattering processes, Coherent and Incoherent Transport in Resonant Tunneling Structures; B. Vinter, et al. Quantum Coherence and Phase Randomization in Series Resistors; M. Büttiker. Charge Buildup, Intrinsic Bistability and Energy Relaxation in Resoant Tunneling Structures: High Pressure and Magnetic Field Studies; L. Eaves, et al. Multiple-Barrier and Low-Dimensional Systems: Miniband Transport and Resonant Tunneling in Superlattices; J.F. Palmier. Transport in Superlattices: Observation of Negative Differential Conductance by Field Induced Localization and Its Equivalence with the Esaki-Tsu Mechanism: Scattering Controlled Resonances in Superlattices; F. Capasso, et al. Device Structures: High-Frequency Oscillators Based on Resonant Tunneling; T.C.L.G> Sollner, et al. 39 additional articles. Index.

I. Intracellular Communications.- Tissue Specificity and Cell Death are Associated with Specific Alterations in Nuclear Matrix Proteins.- Mechanism of Growth Regulation in Androgen Responsive Cells.- The Impact of Androgen, Extracellular Matrix, and Stroma upon Proliferation and Differentiation of Benign and Malignant Prostate Epithelial Cells.- Therapeutic Approaches to Activating Programmed Cell Death of Androgen-Independent Prostatic Cancer Cells.- Cell Motility and Structural Harmonics in Prostate Cancer.- Panel Discussion.- II. Growth Factors - 1.- Studies of the Endocrine and Paracrine Effect of Tumor Produced Factors in Human Genitourinary Cancers.- Fibroblast Growth Factor: Implications in the Etiology of Benign Prostatic Hyperplasia.- Fibroblast-Mediated Human Epithelial Tumor Growth and Hormonal Responsiveness In Vivo.- Polyamine Requirement of Prostate Cancer Cell Proliferation.- Heparin-Binding (Fibroblast) Growth Factor/Receptor Gene Expression in the Prostate.- Characterization and Partial Purification of a Non - Heparin-Binding Prostate Growth Factor From Cancerous Human Prostate.- Panel Discussion.- Growth Factors - 2.- Transforming Growth Factor a: A Potential Autocrine Growth Regulator in Prostatic Carcinoma.- Prostatic Growth Factors (PrGFs) - From the Identification of Probasin to the Role of PrGFs.- Urogenital Sinus Derived Growth Inhibitory Factor.- Growth Factor Antagonists in Prostate Cancer: Suramin and Cytotoxic Polyamines as Potential Therapy.- Transforming Growth Factors in Human Prostate Cancer.- Gene Products as the Motivating Force in the Prostate Cell's Response to Androgens.- Panel Discussion.- III. Steroid Receptors.- Molecular Biology of Prostate - Specific Antigen.- Structure and Expression of the Androgen Receptor in Normal Tissues and in Prostate Carcinoma Cell Lines.- Structural Analysis and Gene Expression of TR2 Receptor and TR3 Receptor.- cDNA Cloning, Antibody Production and Immunohistochemical Localization of the Androgen Receptor.- New Approaches to Studies on the Androgen Receptor.- Specific Receptors for Vitamin D3 in Human Prostatic Carcinoma Cells.- Panel Discussion.- IV. Poster Presentations.- Role of Androgens and Extracellular Matrix in the Growth and Differentiation of Benign and Malignant Prostatic Epithelial Cells.- Tissue Specificity and Cell Death Are Associated with Specific Alterations in Nuclear Matrix Proteins.- ElTect of Transformation on Rat Prostatic Fibroblasts: Alterations In Extracellular Matrix and Cytoskeleton Gene Expression with Retention of Androgen Responsiveness and Androgen Receptor Expression.- A Potential Role for the MDR-1 Gene in the Development of Androgen-Independent Tumors.- Relevance of Low Androgen Levels and Adrenal Androgens in the Growth of Transplantable Human Prostatic Carcinomas.- Growth-Stimulating Effect of Growth Factor(s) from Androgen Independent Tumor Cells (CS 2-Cell) on Androgen Responsive Tumor Cells.- The Cellular Form of Human Prostatic Acid Phosphatase May Function as a Phosphotyrosyl Protein Phosphatase in Cells.- Expression of Prostate Antigen in LNCaP Cells in Culture.- Allelic Expression of the Mouse Ren-1 Genes in the Anterior Prostate (Coagulating Gland).- V. Dna Structure and Gene Expression.- Genomic Alterations in Prostatic Cancer.- Regulation of Gene Expression in the Prostate.- Androgen Regulation of HBGF I-(aFGF) and Characterization of the Androgen-Receptor mRNA in the Human Prostate Carcinoma Ceil Une - LNCaP/A-dep.- DNA Methylation, Differentiation and Cancer.- Evidence for tbe Involement of Genetic Differences and Mesenchymal Factors in the Progression of Oncogene - Induced Prostate Cancer in Reconstituted Mouse Prostate.- Differential Hybridization Analysis as a Tool to Study Prostatic Cancer Metastasis.- Molecular Biology of Androgen Acceptors in Prostatic Cancer Cells.- Panel Discussion.- Panel Discussion.- Panel Discussion.- Panel Discussion.- Panel Discussion.- Contributors.

Background on Semimagnetic Semiconductors.- Thermodynamics and Crystal Growth of Diluted Magnetic Semiconductors.- Band Structure and Theory of Magnetic Interactions in Diluted Magnetic Semiconductors.- Transport phenomena in Semimagnetic Semiconductors.- Experimental Studies of the d-d Exchange Interactions in Diluted Magnetic Semiconductors.- Bound Magnetic Polarons in Diluted Magnetic Semiconductors.- Magnetooptic Properties of Wide Gap II1?xMnxVI Semimagnetic Semiconductors.- II-Fe-VI Semimagnetic Semiconductors.- Semimagnetic IV-VI Compound Semiconductors.- Semimagnetic Semiconductor Superlattices.- Magnetism of Fe-Based Diluted Magnetic Semiconductors.

Flavonoids in the Living System: An Introduction; J.A.Manthey, B.S. Buslig. Flavonoids and Arbucular-Mycorrhizal Fungi; H. Vierheilig, et al the Role of Glycosylation in Flavonol-Induced Pollen Germination; L.P. Taylor, et al. Expression of Genes for Enzymes of the Flavonoid Biosynthetic Pathway in the Early Stages of the Rhizobium-Legume Symbiosis; H.I. McKhann, et al. Prospects for the Metabolic Engineering of Bioactive Flavonoids and Related Phenylpropanoid Compounds; R.A. Dixon, et al. Flavonoid Accumulation in Tissue and Cell Culture; Studies in Citrus and other Plant Species; M.A. Berhow. Flavonoids of the Orange Subfamily Aurantioideae; J.A. Manthey, K. Grohmann. Citrus Flavonoids: A Review of Past Biological Activity Against Disease: Discovery of New Flavonoids from Dancy Tangerine Cold Pressed Peel Oil Solids and Leaves; A. Montanari, et al. Differentiation of Soy Sauce Types by HPLC Profile Pattern Recognition: Isolation of Novel Isoflavones; E. Kinoshita, et al. Induction of Oxidative Stress by Redox Active Flavonoids; W.F. Hodnick, et al. Flavonoids in Foods as in Vitro and in Vivo Antioxidants; J.A. Vinson. 7 Additional Chapters. Index.

Cellular Mechanisms Involved in the Modulation of the Immune System by Drugs of Abuse; S.L. Chang, et al. Immunomodulation of Macrophage Functions by Opioids; R. Gomez-Flores, R.J. Weber. Morphine Accelerates the Progression of Sepsis in an Experimental Sepsis Model; S. Roy, et al. Morphine Depresses Macrophage Numbers and Function in Mouse Spleens; T.K. Eisenstein, et al. Morphine Depresses Macrophage Numbers and Function in Mouse Spleens; T.K. Eisenstein, et al. Centrally-Mediated Opioid-Induced Immunosupression: Elucidation of Sympathetic Nervous System Involvement; W.J. Brinkman, et al. The Expression of Interleukin-1beta Converting Enzyme (ICE) in Rat is Decreased Following Chronic Exposure to Morphine; Gao-de Wu, et al. Opioid Receptor Gene Expression in the Porcine Immune System; M.S. Pampusch, et al. The Effects of Interaction Between Morphine and Interleukin-1 on the Immune Response; S.L. Chang, et al. Morphine Alters the Immune Response to Influenza Virus Infection in Lewis Rats; M.E. Coussons-Read, et al. Orphan Opioid Receptor Oligonucleotide Inhibit HIV-1 Expression in Human Brain Cells; C.C. Chao, et al. Opiate Effects on in Vitro Human Retroviral Infection; S.B.Nyland, et al. FIV: A Lentivirus Model for Opiate Effects on Disease; J.-N. Billaud, T.R. Phillips. 21 Additional Articles. Index.

Session I: Left Ventricular Hypertrophy: Structural Aspects and Mechanisms.- 1. Relations of Left Ventricular Geometry and Function to Prognosis in Hypertension.- 2. Left Ventricular Hypertrophy, Arterial Compliance, and Aging.- 3. Left Ventricular Hypertrophy and Arterial Blood Pressure in Experimental Models of Hypertension.- 4. Regulation and Role of Myocardial Collagen Matrix Remodeling in Hypertensive Heart Disease.- 5. Ultrasonic Reflectivity of the Heart: A Measure of Fibrosis?.- 6. Local Angiotensin II and Myocardial Fibrosis.- 7. Left Ventricular Anatomy and Function in Primary Aldosteronism and Renovascular Hypertension.- Session II: Pathophysiological and Molecular Aspects.- 8. Hypertension Differentially Affects the Expression of the Gap Junction Protein Connexin43 in Cardiac Myocytes and Aortic Smooth Muscle Cells.- 9. Modulation of Cardiac Hypertrophy by Estrogens.- 10. Salt Sensitivity and Left Ventricular Hypertrophy.- 11. Volume Overload, Atrial Natriuretic Peptide, and Left Ventricular Hypertrophy.- 12. The Renin-Angiotensin System Gene Polymorphism and Left Ventricular Hypertrophy.- 13. Renin-Angiotensin System Gene Polymorphisms and Left Ventricular Hypertrophy: The Case against an Association.- Session III: Pathophysiological and Therapeutic Aspects.- 14. Left Ventricular Hypertrophy and Arterial Hypertrophy.- 15. Relationship between Cardiac Hypertrophy and Microalbuminuria.- 16. Physiological versus Pathological Hypertrophy: The Athlete and the Hypertensive.- 17. Bradykinin and Cardiac Protection.- 18. Left Ventricular Hypertrophy and Sympathetic Activity.- 19. Hypertension, Left Ventricular Hypertrophy, and Heart Rate Variability.- 20. Comparison of Meta-Analyses of Therapeutic Studies on Regression of Left Ventricular Hypertrophy.- 21. Comparison of Therapeutic Studies on Regression of Left Ventricular Hypertrophy.- 22. Prognostic Significance of Left Ventricular Hypertrophy Regression.- Session IV: Myocardial Ischemia.- 23. Hypertension and Coronary Microvascular Disease.- 24. Myocardial Perfusion in Hypertensive Patients with Normal Coronary Arteries.- 25. Endothelial Dysfunction in Hypertension.- 26. Endothelial Dysfunction in Hypertensives: An Uncertain Association.- 27. Hypertension, Left Ventricular Hypertrophy, and Coronary Flow Reserve.- 28. Hypertensive Heart Disease, Ventricular Dysrhythmias, and Sudden Death.- 29. Hypertension and Heart Failure.- Speakers.

General Aspects: Nutritionally Related Disorders/Diseases in Africans: Highlights of Half A Century of Research, with Special Reference to Unexpected Phenomena; A.R.P. Walker. The Evolving Epidemiology of Fiber & Heart Disease; C. Humble. Complex Carbohydrates: Overview on Complex Carbohydrates; J. De Vries. Dietary Guidelines and Complex Carbohydrates; B. Schneeman. Soluble Fiber: Soluble Fiber and Hypertension; J.M. Keenan. Soluble Fiber and Energy Regulation: Current Knowledge and Future Directions; S. Roberts. Short Chain Fatty Acids: Butyrate and the Colonocyte: Production, Absorption, Metabolism and Nutrient Utilization; M.J. McBurney. Nutrients Contributing to the Fiber Effect: Resistant Starch-An Update on Its Physiological Effects; N.G. Asp. Health Benefits of Non-Digestible Oligosaccharides; M. Roberfroid. Fiber and Disease: Fiber and Cancer Protection: Mechanisms; D. Klurfeld. Dietary Fiber & Bile Acid Metabolism-An Update; J.A. Story. Workshop Reports: Dietary Guidelines/RDA/Daily Value; B. Schneeman. Soluble Dietary Fiber; J. Marlett. 19 Additional Articles. Index.

Introduction: Serpins: From the Way It Was to the Way It Is; J. Travis. Serpins: A Mechanistic Class of Their Own; S.R. Stone, et al. Coagulation: Antithrombin-A Bloody Important Serpin; I. Björk, S.T. Olson. Heparin Cofactor II; D.M. Tollefsen. Neurobiology and Cancer: Regulation of Neurons and Astrocytes by Thrombin and Protease Nexin-l: Relationship to Brain Injury; D.D. Cunningham, F.M. Donovan. Maspin: A Tumor Suppressing Serpin; R. Sager, et al.. Fibrinolysis: The Role of Reactive-Center Loop Mobility in the Serpin Inhibitory Mechanism; D.A. Lawrence. Substrate Specificity of Tissue Type Plasminogen Activator; E.L. Madison. Development and Reproduction: Biology of Progesterone-Induced Uterine Serpins; P.J. Hansen, W.-J. Liu. Serpins from an Insect, Manduca sexta; M.R. Kanost, H. Jiang. Inflammation: Serpins and Programmed Cell Death; G.S. Salvesen. Noninhibitor Serpins: Structure-Function Studies on PEDF: A Noninhibitory Serpin with Neurotropic Activity; S.P. Becerra. Abstracts: Coagulation, Neurobiology and Cancer. Fibrinolysis, Development and Reproduction. Inflammation and Noninhibitor Serpins. 10 Additional Articles. Index.

Human Reproduction-The Missing Parts of the Puzzle; B.P. Setchell. Genes, Chromosomes and Fertility: Human Y Chromosome Deletions in Yq11 and Male Fertility; P.H. Vogt. Frequency of Y-Chromosome Microdeletions; (Yq11.22-23) in Men with Reduced Sperm Quality Requesting Assisted Reproduction; A. Bonhoff, et al. Germ Cell Differentiation and Tumorigenesis: Endocrine Control of Germ Cell Proliferation in the Primate Testis: What Do We Really Know?; G.F. Weinbauer, E. Nieschlag. The Role of the Testicular Accessory Cells: Molecular Pathophysiology of the Pituitary-Gonadal Axis; M. Simoni, et al. Compartmentalization, Vascularization and Angiogenesis: Compartmentalization of the Intertubular Space in the Human Testis; A.F. Holstein, M. Davidoff. Post-Testicular Sperm Maturation: The Role of Apocrine Released Proteins in the Post-Testicular Regulation of Human Sperm Function; G. Aumüller, et al. Control of the Male and Female Tracts: Interactions Between Leukocytes and the Male Reproductive System: The Unanswered Question; A.G. Rossi, R.J. Aitken. Gamete Interaction and Fertilization: The Cell Biology of Fertilization; R.J. Aitken. 45 Additional Articles. Index.

Brain Tryptophan Perturbation in Hepatic Encephalopathy: Implications for Effects by Neuropsychoactive Drugs in Clinical Practice; F. Bengtsson, et al. Hepatic Encephalopathy in Acute Liver Failure: Role of the Glutamate System; A. Michalak, et al. Glutamate and Muscarinic Receptors in the Molecular Mechanisms of Acute Ammonia Toxicity and of Its Prevention; M.D. Miñana, et al. Studies on the Pharmacological Properties of Oxindole (2-Hydroxyindole) and 5-Hydroxyindole: Are They Involved in Hepatic Encephalopathy?; F. Moroni, et al. The Involvement of Ammonia with the Mechanisms That Enhance GABA-ergic Neurotransmission in Hepatic Failure; E.A. Jones, A.S. Basile. Direct Enhancement of GABA-ergic Neurotransmission by Ammonia; J.-H. Ha, et al. The Peripheral Benzodiazepine Receptor and Neurosteroids in Hepatic Encephalopathy; M.D. Norenberg, et al. Ornithine Aminotransferase as a Therapeutic Target in Hyperammonemias; N. Seiler. Sparse-Fur (spf) Mouse as a Model of Hyperammonemia: Alterations in the Neurotransmitter Systems; I.A. Qureshi, K.V.R. Rao. Abnormal Gene Expression Causing Hyperammonemia in Carnitine-Deficient Juvenile Visceral Steatosis (JVS) Mice; T. Saheki, et al. 7 Additional Articles. Index.

Introduction. Mono(ADP-ribosyl)Transferases and Related Enzymes: Emerging Gene Families; F. Koch-Nolte, F. Haag. Mono-ADP-ribosylation in Prokaryotes. Crystal Structure of Diphtheria Toxin Bound to Nicotinamide Adenine Dinucleotide; C.E. Bell, D. Eisenberg. Molecular Approaches to Eukaryotic Mono(ADP-ribosyl)Transferases. Sequence and Structural Links Between Distant ADp-ribosyltransferase Families; F. Bazan, F. Koch-Nolte. Moni(ADP-ribosyl)Transferases in the Immune System. Regulation of Cytotoxic T Cell Functions by a GPI-anchored Ecto-ADP-ribosyltransferase; J. Wang, et al. Mono-ADP-ribosylation in Other Animal Tissues. An ADP-Ribosyltransferase from Bovine Erythrocytes Apparently Specific for Cysteine Residues; S. van Heyningen, B. Saxty. Physiology of GPI-Anchored Proteins. Cell Surface Dynamics of GPI-anchored Proteins; F.R. Maxfield, S. Mayor. Relationship of ADP-Ribosyltransferases to NAD+ Glycohydrolases and ADP-ribosyl Cyclases. ADp-Ribose in Glycation and Glycoxidation Reactions; E.L. Jacobson, et al. Special Lecture Commemorating the Retirement of Professor Heinz-Günter Thiele. Appendix. 28 Additional Lectures. 24 Poster Reports. Index.

Historical Perspectives. Morphology of Chemoreceptors. Re-Examination of the Carotid body Ultrastructure with Paying Attention to the Intercellular Membrane Apposition; H. Kondo, H. Iwasa. Biochemistry of Chemoreceptor Mechanisms. Developmental Aspects of Chemoreceptors. Mechanisms of Carotid Chemoreceptor Resetting After Birth: in vitro Studies; J.L. Carroll, et al. Biophysics of Ionic Channels in Chemoreceptors. Molecular Biology of Chemoreceptors. Evaluation of Gene Expression in the Rat Carotid Body Using the Differential Display Technique; J. Chen, et al. Generation of Chemosensory Activity. transmitters Involved in Chemoreception: Acetylcholine. Release of Acetylcholine from the in vitro Cat Carotid Body; R.S. Fitzgerald, M. Shirahata. Transmitters Involved in Chemoreception: Catecholamines. Dopamine Efflux from the Carotid Body During Hypoxic Stimulation; P. Zapata, et al. Transmiters Involved in Chemoreception: Adenosine and Peptides. Transmitters Involved in Chemoreception: Carbon Monoxide and Nitric Oxide. Chemoreflex Pathways. Coherence of Chemosensor Discharges in Catas' Carotid Nerves. Cooperative Inputs or Redundant Afferences?; J. Alcayaga, et al. Chemoreceptors in Ventilatory Regulation. Chemoreflex Integration and Effectors. 65 Additional Articles. Index.