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In almost all cases, stem cells have to be engineered, sometimes for functional improvement, in many cases to produce large numbers of cells, and frequently to achieve efficient and specific differentiation in the cell type(s) of interest.
This book reviews the development of cell-free production platforms and offers an authoritative perspective of the latest advances and methodologies in cell-free production systems. Readers will discover the biomanufacturing potential of in vitro biotransformation (ivBT) employing purified cascade multi-enzymes, the development of hydrogel-based multi-enzymatic systems for biosynthesis, and novel insights into the optimization of biocatalytic processes. Additionally, the book explores the cell-free production and regeneration of cofactors, shedding light on strategies to enhance the efficiency and sustainability of cellular processes.In this book, particular attention is given to the progress of cell-free in vitro evolution techniques for optimizing enzyme performance, and the book also presents the integration of rapid and finely-tuned expression systems for deployable sensing applications, revolutionizing the field of biosensing. The synthesis and electrophysiological analysis of multipass voltage-gated ion channels tethered in microsomal membranes are explored, providing a deep understanding of cellular function at the molecular level. Lastly, the book covers compartmentalized cell-free expression systems for building synthetic cells, showcasing the potential for constructing artificial cellular systems with unique functionalities.Given its breadth, this book appeals to academics, researchers, and professionals interested in the forefront of biotechnology, and together with the companion volume ¿Cell-free Macromolecular Synthesis¿, both books highlight the research progresses on the basic and applied research of cell-free production systems in the last few years, being invaluable resources in the field.Chapter ¿Cell-free synthesis and electrophysiological analysis of multipass voltage-gated ion channels tethered in microsomal membranes¿ is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
This resource examines trends in modern biotechnology, covering all aspects of this interdisciplinary field.
Anaerobic digestion is a major field for the treatment of waste and wastewater. In addition, the applications for treatment of waste and wastewaters are presented along with the latest knowledge on process control and regulation of anaerobic bioprocesses.
1 G. Liebezeit: Aquaculture of "Non-Food Organisms" for Natural Substance Production.- 2 S. Lang, M. Hüners, V. Lurtz: Bioprocess Engineering Data on the Cultivation of Marine Prokaryotes and Fungi.- 3 K. Muffler, R. Ulber: Downstream Processing in Marine Biotechnology.- 4 M.-L. Bourguet-Kondracki, J.-M. Kornprobst: Marine Pharmacology: Potentialities in the Treatment of Infectious Diseases, Osteoporosis and Alzheimer¿s Disease.- 5 J. Hassfeld, M. Kalesse, T. Stellfeld, M. Christmann: Asymmetric Total Synthesis of Complex Marine Natural Products.- 6 K.H. Chu, C.Y. Tang, A. Wu, P.S.C. Leung: Seafood Allergy: Lessons from Clinical Symptoms, Immunological Mechanisms and Molecular Biology.-
This book covers trends in modern biotechnology. It treats all aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science.
This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community.This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology.
This book review series presents current trends in modern biotechnology. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.
This book review series presents current trends in modern biotechnology. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors.
Antenna Mutants, Domestication, by Roberto BassiHeterotrophic Cultivation, by William McCaffreyChlorella for industrial applications: Advances and prospective, by Feng ChenCarotinoide, by Carola GriehlEngineering the algal chloroplast for synthesis of therapeutic proteins, by Saul PurtonDesign Concepts and recent developments of photobioreactors, by Clemens PostenEfficiency of flat plate reactors, by Mario TrediciMeasuring modelling and control, by Olivier BernardMicroalgae in Life Support Systems, by Klaus SlenzkaHeterotrophic oil production, by Makato Watanabe
1 R. Levy, M.W. Jornitz: Types of Filtration.- 2 T. Meltzer: Modus of Filtration.- 3 O.W. Reif: Microfiltration Membranes: Characteristics and Manufacturing.- 4 M. W. Jornitz: Filter Construction and Design.- 5 R. Madsen: Filter Validation.- 6 M. W.Jornitz: Integrity Testing.-
Enzymes that are operationally stable at high pH (also known as alkaline active enzymes) are desirable in several applications such as detergent formulating and leather tanning processes, and they are among the major selling enzymes and the most important industrial enzymes.
In almost all cases, stem cells have to be engineered, sometimes for functional improvement, in many cases to produce large numbers of cells, and frequently to achieve efficient and specific differentiation in the cell type(s) of interest.
Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.
Alongside disposable filter capsules, membrane chromatography units, tubing, connectors, flexible containers processing or containing fluids, freezer systems, mixers and pumps, and fully c- trolled disposable bioreactors of up to 2,000 L culture volume are already available on the market.
Automated Measurement and Monitoring of Bioprocesses: Key Elements of the M3C Strategy, by Bernhard Sonnleitner Automatic Control of Bioprocesses, by Marc Stanke, Bernd Hitzmann An Advanced Monitoring Platform for Rational Design of Recombinant Processes, by G.
Alongside disposable filter capsules, membrane chromatography units, tubing, connectors, flexible containers processing or containing fluids, freezer systems, mixers and pumps, and fully c- trolled disposable bioreactors of up to 2,000 L culture volume are already available on the market.
This resource examines trends in modern biotechnology, covering all aspects of this interdisciplinary field.
Part I: Introduction.- The Sustainability and Life Cycle Assessments of Industrial Biotechnology: An Introduction.- Part II: Background.- History, Current State, and Emerging Applications of Industrial Biotechnology.- Economic Aspects of Industrial Biotechnology.- Part III: Industrial Biotechnology from an Assessment Perspective.- Environmental Aspects of Industrial Biotechnology.- Societal and Ethical Aspects of Industrial Biotechnology.- Sustainability and Life Cycle Assessments in Industrial Biotechnology: A Review of Current Approaches and Future Needs.- Social Life Cycle Assessment for Industrial Biotechnology.- Part IV: Specific Methods and Applications.- Assessing Land Use and Biodiversity Impacts of Industrial Biotechnology.- Risk Assessment of Processes and Products in Industrial Biotechnology.- Green Chemistry and its Contributions to Industrial Biotechnology.- Application of geobiotechnology in mining, mineral processing and metal recycling.- Assessing Industrial Biotechnology Products with LCA and Eco-Efficiency.
This book reviews the latest advances in multiple fields of plant biotechnology and the opportunities that plant genetics, genomics and molecular biology have offered for agriculture improvement.
This book presents the latest findings on amino acid fermentation and reviews the 50-year history of their development.
This book review series presents current trends in modern biotechnology. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors.
This book presents the latest findings on amino acid fermentation and reviews the 50-year history of their development.
This book review series presents current trends in modern biotechnology. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.
Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.
This book review series presents current trends in modern biotechnology. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.
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